scholarly journals Assessment Strategies to Improve the Diagnosis of Osteomyelitis in Diabetic Foot Using Radiography

2018 ◽  
Vol 1 (06) ◽  
pp. 34-36
Author(s):  
Jose Maria Pereira De Godoy
Keyword(s):  
Diabetes Mellitus ◽  
Clinical Trial ◽  
Diabetic Foot ◽  
Diabetic Patients ◽  
Bone Surface ◽  
Bacterial Cultures ◽  
System Disease ◽  
Diagnostic Window ◽  
Assessment Strategies ◽  
Positive Results

Background:  Diabetes mellitus is a multi-system disease that affects people of both genders and any age or ethnic group. Foot wounds are common and can lead to loss of limb in cases of therapeutic failure. Aim: The aim of this study was to correlate initial diagnoses of osteomyelitis by radiography with bacterial cultures and identify ways to improve the diagnosis using this method. Method: In a prospective random clinical trial, the correlation between radiographs and bacterial cultures were evaluated in diabetic patients undergoing amputation of toes or part of the foot in Hospital de Base in the period from October 2010 to January 2012. Radiographs were considered suggestive of osteomyelitis if they identified an irregular bone surface, obliteration, bone resorption or periosteal resorption. The diagnostic impression from imaging was compared to the results of a bacterial growth culture prepared using bone removed during surgery. Results: An analysis of the radiographs identified 29 patients with results that were suggestive of osteomyelitis. Of these, the results of 27 bacterial cultures were positive. Eight of the 22 radiographs that were not suggestive of osteomyelitis were negative and 14 were positive. Conclusion: The diagnosis of osteomyelitis in diabetic foot can be improved by stratifying the results, taking the positive results and creating a diagnostic window with another diagnostic evaluation in cases that are initially negative.

scholarly journals Staphylococcus aureus strains isolated from diabetic foot ulcers. Identification of the antibiotic resistant phenotypes

2013 ◽  
Vol 20 (4) ◽  
pp. 389-393 ◽  
Author(s):  
Teodora Chiţă ◽  
Delia Muntean ◽  
Luminiţa Badiţoiu ◽  
Bogdan Timar ◽  
Roxana Moldovan ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Staphylococcus Aureus ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Foot Ulcers ◽  
Resistance Pattern ◽  
Diabetic Patients ◽  
Diabetic Foot Ulcers ◽  
Bacterial Strains ◽  
Diabetes Clinic

Abstract Background and aims: Infected foot ulcer is one of the most feared complications of diabetes mellitus. Staphylococcus aureus is the most frequently isolated pathogen in diabetic foot infections. The aim of this study was to evaluate the prevalence of S. aureus strains involved in producing foot infections in diabetic patients and the antibiotic resistance pattern of these strains. Material and methods: The study included 33 S. aureus strains isolated from 55 diabetic foot ulcers. The subjects were selected from the 2465 patients with diabetes mellitus hospitalized in the Timişoara Diabetes Clinic, between 2011 and 2013. Germs’ identification relied on cultural and biochemical characteristics. Final identification and antimicrobial testing were performed using the Vitek 2 (Bio Merieux France) automatic analyzer. Results: All the 55 samples collected from diabetic foot ulcers were positive. We isolated 64 bacterial strains (some samples were positive for 2 microorganisms). The most frequently isolated germ was S. aureus, in 33 samples (51.56%). All these S. aureus strains showed resistance to benzylpenicillin, while only 33.33% were methicillin-resistant (MRSA). Conclusions: The most frequently isolated germ in the wound secretions from diabetic foot ulcers was S. aureus. The highest percentage of antimicrobial resistance was recorded to benzylpenicillin and erythromycin.

scholarly journals Prevalence of Diabetic Foot Ulcer and Associated Factors among Adult Diabetic Patients Who Attend the Diabetic Follow-Up Clinic at the University of Gondar Referral Hospital, North West Ethiopia, 2016: Institutional-Based Cross-Sectional Study

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Tesfamichael G. Mariam ◽  
Abebaw Alemayehu ◽  
Eleni Tesfaye ◽  
Worku Mequannt ◽  
Kiber Temesgen ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Cross Sectional Study ◽  
Care Practice ◽  
Diabetic Patients ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated

Diabetes mellitus is a metabolic disorder which is characterized by multiple long-term complications that affect almost every system in the body. Foot ulcers are one of the main complications of diabetes mellitus. However, there is limited evidence on the occurrence of foot ulcer and influencing factors in Ethiopia. An institutional-based cross-sectional study was conducted in Gondar University Hospital, Ethiopia, to investigate foot ulcer occurrence in diabetic patients. Systematic random sampling was used to select 279 study participants. Bivariate and multivariable logistic regression model was fitted to identify factors associated with diabetic foot ulcer. Odds ratio with 95% confidence interval was computed to determine the level of significance. Diabetic foot ulcer was found to be 13.6%. Rural residence [AOR = 2.57; 95% CI: 1.42, 5.93], type II diabetes mellitus [AOR = 2.58; 95% CI: 1.22, 6.45], overweight [AOR = 2.12; 95% CI: 1.15, 3.10], obesity [AOR = 2.65; 95% CI: 1.25, 5.83], poor foot self-care practice [AOR = 2.52; 95% CI: 1.21, 6.53], and neuropathy [AOR = 21.76; 95% CI: 8.43, 57.47] were factors associated with diabetic foot ulcer. Diabetic foot ulcer was found to be high. Provision of special emphasis for rural residence, decreasing excessive weight gain, managing neuropathy, and promoting foot self-care practice would decrease diabetic foot ulcer.

scholarly journals The Prevalence of Giardia Intestinalis in Dyspeptic and Diabetic Patients

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Gözde Derviş Hakim ◽  
Şafak Kızıltaş ◽  
Hilmi Çiftçi ◽  
Şafak Göktaş ◽  
İlyas Tuncer
Keyword(s):  
Diabetes Mellitus ◽  
Giardia Intestinalis ◽  
Diabetic Patients ◽  
Elisa Method ◽  
Number Of Patients ◽  
Significant Difference ◽  
Patients With Diabetes ◽  
Stool Specimens ◽  
Positive Results ◽  
Healthy Persons

Background and Aims. We aimed to investigate the prevalence of Giardiasis in patients with dyspepsia and patients with diabetes mellitus. Methods. 400 patients and 100 healthy persons were included in this clinical prospective study. The number of patients in each group was equal, 200 dyspeptic and 200 diabetic, respectively. The antigen of G. lntestinalis was determined in the stool specimens by ELISA method. Results. The frequency of Giardiasis was 7% in dyspeptic and 15% in diabetic patients. There was no positive results in any of the healthy persons. There was a significant difference in prevalence rate of Giardiasis between patients with dyspepsia and diabetes mellitus (P<0.05). Conclusions. These results revealed that the prevalence of Giardiasis in dyspepsia and with diabetes mellitus was high in our country. This is the first study investigating the prevalence of Giardiasis in diabetic patients. To investigate Giardiasis in diabetic patients, who have dyspepsia or not, may be a good approach for public health.

scholarly journals Effect of Health Education on Improving the Knowledge among Diabetes Mellitus Patients in the Prevention of Diabetic Ulcer in Regional Hospital of Tidore Island

2021 ◽  
Vol 4 (4) ◽  
pp. 379-384
Author(s):  
Haeril Amir ◽  
Nur Wahyuni Munir
Keyword(s):  
Diabetes Mellitus ◽  
Health Education ◽  
Diabetic Foot ◽  
Regional Hospital ◽  
Foot Ulcers ◽  
Control Group ◽  
Diabetic Patients ◽  
Diabetic Foot Ulcers ◽  
Diabetic Ulcer ◽  
Diabetic Ulcers

International  Diabetes  Federation  (IDF) reported that the number of diabetes mellitus patients worldwide increases every year. Diabetes mellitus is a chronic disease due to damage to the pancreas in producing enough insulin and characterized by impaired metabolism of fats, increased blood sugar, carbohydrates and protein both absolutely and relatively. Diabetic foot ulcers (DFU) are among the most common complications in diabetic patients and are associated with high mortality, morbidity, and health costs.   This study was to determine the effect of health education on knowledge improvement about diabetic ulcers in the regional hospital of Tidore Islands.  This research is a quasi-experimental type with a pretest-posttest without a control group design. The research sample consisted of 30 respondents who met the inclusion criteria. Data were analyzed using a paired test and processed with statistic version 21. Based on the research results, there was an improved knowledge in pre and post-health education counseling, where the average score before health education counseling was 11.6. After health counseling, the average value was 15.0. The results showed the effect of knowledge in the prevention of diabetic ulcers with a p-value =0,000.  Health education is an effort to improve patient's ability to prevent diabetic foot ulcers that have been proven in several scientific studies. Health education methods provide additional information so that patients who previously wondered about their disease can directly ask health workers. Health education affects the knowledge improvement of Diabetes Mellitus patients in the Regional hospital of Tidore Islands  

scholarly journals Evaluating the Effects of Spraying Oxytetracycline on Diabetic Foot Ulcers: A Randomized Clinical Trial

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Gholam Hosein Kazemzadeh ◽  
Hasan Ravari ◽  
Masomeh Nabavizadeh ◽  
Saeid Pasban Noghabi
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Diabetic Foot ◽  
Intervention Group ◽  
Purulent Discharge ◽  
Foot Ulcers ◽  
Diabetic Patients ◽  
Diabetic Foot Ulcers ◽  
Significant Difference ◽  
And Control

Background: Diabetic foot ulcers (DFUs) can be created due to neuropathy and peripheral vascular disease in the lower limbs. Objectives: This study aimed to evaluate the effects of spraying oxytetracycline on DFU. Methods: This randomized clinical trial was conducted on 60 diabetic patients suffering from DFU. The patients were randomly assigned into two equal groups of intervention and control (n = 30 each). While all subjects received antibiotic therapy, blood sugar control, and, if necessary debridement, the intervention group received oxytetracycline spraying on the DFUs twice a day. After the intervention, the patients were visited every week (for three weeks), photos were taken of the DFUs by special software, and the size of the DFUs was checked. The DFUs were also studied in terms of purulent discharge, the smell, and erythema, and edema around the ulcer. After three weeks, the healing of ulcers were compared in the two groups. Data were gathered and analyzed using the SPSS software version 11.5, descriptive statistical test, chi-square, and t-test. Results: Before the study, the size of the DFUs in the intervention and control groups was 110.87 ± 38.3 and 127.12 ± 40 mm2, respectively. After the treatment, the alterations in the intervention group in the first, second, and third weeks were 14.90 ± 14.41, 26.93 ± 18.86, and 41.25 ± 19.51, respectively. Also, in the control group, the alterations were 19.45 ± 1.35, 23.78 ± 5.31, and 13.29 ± 8.75, respectively. There was a statistically significant difference in the size of DFUs between the two groups (P < 0.05). Conclusions: According to the results, spraying oxytetracycline on DFUs facilitated the process of healing. Thus, it can be used as an affordable, available, and effective method.

scholarly journals A CLINICAL STUDY ON THE MANAGEMENT OF STHAULYA BY TRIKATU CHURNA

2020 ◽  
Vol p4 (05) ◽  
pp. 2382-2388
Author(s):  
Ankur Saxena ◽  
Sunil K Gupta ◽  
Jolly Saxena ◽  
Niranjan S
Keyword(s):  
Diabetes Mellitus ◽  
Clinical Trial ◽  
Clinical Study ◽  
Signs And Symptoms ◽  
Morbidity Rate ◽  
Mortality And Morbidity ◽  
Anxiety Depression ◽  
Positive Results

Sthaulya / Atisthaulya in Ayurveda comes under the heading of Medoroga which results due to dysfunc-tion of Meda Dhatvagni (factor responsible for nourishment / metabolism of Meda dhatu) and in modern parlance it is equated with Obesity due to its close similarities. It is the main cause for so many complica-tions like Hypertension, Diabetes mellitus, Osteoarthritis, Infertility, Impotency etc. as well as psychologi-cal disturbances like anxiety, depression etc. Thus, the mortality and morbidity rate were high in obese per-sons compared to others. This shows the importance of the need for further researches of effective measures in the management of Sthaulya. Hence in the present study a clinical trial was carried out with Trikatu Churna in the management of Sthaulya (obesity) for 30 days. 30 patients were selected with diag-nosis of Sthaulya out of which 24 completed the treatment. The study concluded with the positive results of Trikatu churna in reducing the signs and symptoms of Sthaulya.

scholarly journals Awareness of diabetic foot disease among patients with diabetes mellitus in Al-Ahsa Saudi Arabia

2021 ◽  
Vol 8 (12) ◽  
pp. 3506
Author(s):  
Abdulaziz S. Aldhafar ◽  
Mohamed Abdullah ◽  
Abdulaziz K. Althafar
Keyword(s):  
Diabetes Mellitus ◽  
Saudi Arabia ◽  
Diabetic Foot ◽  
Diabetic Patients ◽  
Foot Care ◽  
Cross Sectional ◽  
Attitude And Practice ◽  
Diabetic Foot Disease ◽  
Foot Disease ◽  
Knowledge Attitude And Practice

Background: The prevalence of diabetes mellitus (DM) in Saudi Arabia is 18.3% in 2020. One of the most common complications that affects diabetic patients is diabetic foot disease (DFD). Patient education is the most effective way to reduce the complications of DFD.Methods: A cross-sectional study was conducted in the period from January to May 2021. A pretested standardized questionnaire was used to collect information upon knowledge, attitude and practice toward diabetic foot care. Data entry was performed using SPSS.Results: The responses of 480 of which 294 male and 186 female, 41.6% have high school degree, 19.3% have bachelor’s degree and 2.2% have master or Ph. D. degree. The mean age of the respondents was 47 years. The 58% of the participant agreed that they might develop reduce flow to their feet. half of the participant were not aware that smoking can reduce blood flow in their feet. There were only 2.3% of the respondents attended a class on how to care of the foot. Participants who received information about foot care from a nurse and physician were 23% and 9.2% respectively. The 97.5% of the participant would like to know how to care for their foot. 75.8% of participants walk barefoot and 42.2% use a comfortable coated shoe.  Conclusions: Participants have inadequate knowledge, attitude and practice about DFD. providing a structured educational program about diabetic foot care has significant impact on diabetic patient to improve their knowledge and practices and to motivate them to have a positive attitude toward diabetic foot care.

Medical management of the diabetic patient during podiatric surgery

1994 ◽  
Vol 84 (9) ◽  
pp. 432-438 ◽  
Author(s):  
SB Lewis ◽  
CF Biondo ◽  
JC Page
Keyword(s):  
Diabetes Mellitus ◽  
Wound Healing ◽  
Diabetic Foot ◽  
Postoperative Care ◽  
Medical Management ◽  
Perioperative Management ◽  
Diabetic Patients ◽  
Foot Surgery ◽  
Podiatric Surgery ◽  
Enhance Wound Healing

Diabetes mellitus commonly causes complications of the foot that can lead to surgery. The appropriate perioperative management of diabetic patients can reduce the morbidity and mortality associated with diabetic foot surgery and enhance wound healing. The authors review the effects of hyperglycemia, detail preoperative, intraoperative, and postoperative care, and describe anesthetic choices. An algorithm for management of hypoglycemia is offered.

scholarly journals The Association between Cognitive Impairment and Diabetic Foot Care: Role of Neuropathy and Glycated Hemoglobin

2020 ◽  
Vol 27 (1) ◽  
pp. 14-27
Author(s):  
Lorenzo Brognara ◽  
Iacopo Volta ◽  
Vito Michele Cassano ◽  
Emmanuel Navarro-Flores ◽  
Omar Cauli
Keyword(s):  
Diabetes Mellitus ◽  
Cognitive Impairment ◽  
Cognitive Function ◽  
Glycemic Control ◽  
Cognitive Dysfunction ◽  
Cognitive Functions ◽  
Diabetic Foot ◽  
Glycated Hemoglobin ◽  
Diabetic Patients ◽  
Adherence To Treatment

Diabetes mellitus is associated with impairment in cognitive functions which can complicate adherence to self-care behaviors. We evaluated the incidence of cognitive impairment in patients with diabetes mellitus to determine the strength of the association between diabetic foot (a complication that occurs in about 10% of diabetic patients), adherence to the clinician’s recommendations, glycemic control, and cognitive function. A prospective study was carried out in a probabilistic sample of older patients with diabetic foot living in three nursing homes. Cognitive functions were evaluated by the MMSE (Mini-Mental State Examination), the Trail Making test (TMT), and the Michigan neuropathy screening instrument (MNSI). There were no significant associations between cognitive function and neuropathy or foot alterations, although glycated hemoglobin (HB1Ac > 7%) significantly (p < 0.05) associated with MMSE and adherence to treatment in the 1 month follow-up visit. Receiver operating characteristic curve analysis showed that both HB1Ac and the MNSI score significantly (p < 0.05) discriminate subsequent adherence to treatment for foot complication, with a sensitivity of 80.0–73.3% and specificity 70.6–64.7%, respectively. Proper control of foot complications in diabetic patients involves appropriate glycemic control and less severe neuropathy, and seems to be unrelated to cognitive dysfunction, and warrants further studies in order to tailor appropriate treatments to central and peripheral nervous system disorders. Poor glycemic control (Hb1Ac level > 7%) and a neuropathy score of 5.5 in the MNSI are the best-cut off points to discriminate poor adherence to the clinician’s recommendations for self-care behaviors in people with diabetic foot complication. In this study, we observed that foot disorders were associated with impaired global cognitive function in elderly patients (aged ≥ 65). Podiatrists and physicians should consider cognitive dysfunction as an important chronic complication in the management of diabetic foot.

scholarly journals Impact on the Quality of Life and Physiological Parameters in Patients with Diabetes Mellitus

2021 ◽  
Vol 11 (15) ◽  
pp. 6829
Author(s):  
María Reina-Bueno ◽  
Inmaculada C. Palomo-Toucedo ◽  
Manuel Ángel Medina-Núñez ◽  
Pedro V. Munuera-Martínez ◽  
Aurora Castro-Méndez ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Diabetic Foot ◽  
Physiological Parameters ◽  
Physical Parameters ◽  
Diabetic Patients ◽  
Life Questionnaire ◽  
Adult Women ◽  
Patients With Diabetes

The co-existence of complications and diabetes mellitus is related to a worsening in quality of life compared to not presenting comorbidities. This study aimed to investigate whether there is a different impact on quality of life according to gender and to establish the physiological parameters that these patients have in relation to diabetes-related complications. The sampling was continuous non-probabilistic, involving legal age patients with diabetes mellitus. All of the participants were administered the generic SF-36 quality of life questionnaire. The presence of peripheral artery disease was considered from an ankle brachial index <0.9 and grade II to grade IV of the Leriche–Fontaine classification. Nerve dysfunction was detected from a neurotensiometer test, and the presence of diabetic foot was detected from a dermal examination and co-existence with arteriopathy and/or neuropathy. Men presented significantly better quality of life values on the mental health, emotional role and health transition scales. Despite this, in the presence of complications such as vasculopathy, neuropathy or diabetic foot, the perception of well-being changes, showing that men and women face the disease in different ways. Despite the fact that the physical parameters of diabetic patients are similar according to the complications that they present, the adult women in our environment have lower levels of quality of life than men in most cases. This may be related not only to pathophysiological differences but also to sociocultural factors.

Sign in / Sign up

Export Citation Format

Share Document