scholarly journals A CLINICAL STUDY ON THE MANAGEMENT OF STHAULYA BY TRIKATU CHURNA

2020 ◽  
Vol p4 (05) ◽  
pp. 2382-2388
Author(s):  
Ankur Saxena ◽  
Sunil K Gupta ◽  
Jolly Saxena ◽  
Niranjan S
Keyword(s):  
Diabetes Mellitus ◽  
Clinical Trial ◽  
Clinical Study ◽  
Signs And Symptoms ◽  
Morbidity Rate ◽  
Mortality And Morbidity ◽  
Anxiety Depression ◽  
Positive Results

Sthaulya / Atisthaulya in Ayurveda comes under the heading of Medoroga which results due to dysfunc-tion of Meda Dhatvagni (factor responsible for nourishment / metabolism of Meda dhatu) and in modern parlance it is equated with Obesity due to its close similarities. It is the main cause for so many complica-tions like Hypertension, Diabetes mellitus, Osteoarthritis, Infertility, Impotency etc. as well as psychologi-cal disturbances like anxiety, depression etc. Thus, the mortality and morbidity rate were high in obese per-sons compared to others. This shows the importance of the need for further researches of effective measures in the management of Sthaulya. Hence in the present study a clinical trial was carried out with Trikatu Churna in the management of Sthaulya (obesity) for 30 days. 30 patients were selected with diag-nosis of Sthaulya out of which 24 completed the treatment. The study concluded with the positive results of Trikatu churna in reducing the signs and symptoms of Sthaulya.

scholarly journals CONTROLLED RANDOMIZED CLINICAL TRIAL ON USING TALISADI TAILAM FOR TREATING PATIENTS OF TINEA PEDIS W.S.R TO ALASA

AYUSHDHARA ◽  
2021 ◽  
pp. 3104-3108
Author(s):  
Gupta Sudesh ◽  
Manhas Raman, Prasher Aarushi, Sharma Sakshi, Sharma Arun
Keyword(s):  
Clinical Trial ◽  
Clinical Study ◽  
Fungal Infection ◽  
Tinea Pedis ◽  
External Surface ◽  
Signs And Symptoms ◽  
The Body ◽  
Skin Disorders ◽  
Before And After ◽  
Athlete’S Foot

Skin is the general covering of the entire external surface of the body. Because of a large number of its functions, the skin is regarded as an important organ of the body. There are so many skin disorders of which Tenia pedis is a very common fungal infection that affects a significantly large number of people globally. This fungal infection is called Athlete’s foot because it is commonly seen in athletes. In Ayurveda, various skin disorders are described under the heading of kshudraroga. A brief description about Kshudraroga has been given in many Ayurvedic classics. Alasa is a variety of Kshudraroga occurring in between the skin of toes manifesting with Kleda, Kandu, Daha and Ruja. Talisadi tailam mentioned in Sushruta Samhita is an excellent formulation prepared of drugs which are effective against this disease. Current study includes 30 patients from OPD Department of Shalya Tantra, Jammu Institute of Ayurveda and Research, Jammu and Sri Sain Charitable Hospital, Janipur, Jammu diagnosed to have Tenia pedis based on signs and symptoms. Therapeutic effect was evaluated before and after treatment. The present clinical study has shown symptoms of Kandu, Daha, Ruja, Kleda significantly reduced after application of Talisadi tailam.

scholarly journals Transpersonal Psychotherapy At The General Practitioner Office Short Report On A Clinical Trial Evaluating The Efficacy Of Transpersonal Psychotherapy Treatment In Anxiety-Depression

2018 ◽  
Vol 11 (11) ◽  
pp. 78
Author(s):  
Claudio Calcina ◽  
Carmela Sollecito ◽  
Giovanna Calabrese
Keyword(s):  
Clinical Trial ◽  
Full Article ◽  
Clinical Study ◽  
General Practitioner ◽  
Clinical Research ◽  
Short Report ◽  
Transpersonal Psychotherapy ◽  
Anxiety Depression ◽  
Research Studies

The authors report about a clinical study conducted to evaluate the efficacy of Biotransenergetica, a transpersonal psychotherapy approach, in a general practitioner office. In addiction to prove the efficacy of Biotransenergetica this study demonstrates that there is no ostracism or rejection when research is conducted with rigorous methods. (This study will be published as a full article in International Journal Transpersonal Research). KEYWORDS Transpersonal Psychotherapy, Biotransenergetica, Clinical research Studies, Anxiety, Depression.

scholarly journals Clinical Study on Effect of Swarnamritaprashana (Modified Swarna Prashana) in the Management of Shayyamutra in Children

2020 ◽  
Vol 07 (3&4) ◽  
pp. 4-10
Author(s):  
Sudheer Sharma ◽  
Keyword(s):  
Clinical Trial ◽  
Clinical Study ◽  
Diagnostic Criteria ◽  
Nocturnal Enuresis ◽  
Signs And Symptoms ◽  
The Other ◽  
Outpatient Department ◽  
Control Group ◽  
Study Group ◽  
Psychosomatic Problems

Background: The psychosomatic problems of children vary widely in accordance with many factors, which are responsible for children’s physical, mental and emotional progress. In this connection there are so many developmental, behavioral disorders of childhood. Out of them Shayyamutra (enuresis) is the most common messy disorder which is psychosomatic in nature, commonly seen in growing children. Along with other medhya and balya drug it can give better results in Shayyamutra along with Satvavajayachikitsa, that is the reason this study was taken. Materials and Methods: 40 patients of Shayyamutra satisfying diagnostic criteria and age 6-16 years were selected from outpatient department of Kaumarbhritya, SDM College of Ayurveda and Hospital, Hassan. Among them, 20 patients were treated with swarnamritaprashana capsule daily once for two month along with satvavajaya chikitsa in study group. The other 20 patients were treated with ghrita bharjita Godhuma capsule (placebo) daily once for two month along with satvavajaya chikitsa in control group .The patients were assessed on the completion first month, second month and followed again after third month. It was open labelled standard control non-randomized prospective clinical trial from August 2016 to Feb 2017. Result: Statistically significant effect (p<0.05) of swarnamritaprashana capsule along with satvavajaya chikitsa in reduction of all signs and symptoms of nocturnal enuresis after treatment were observed. Conclusion: Swarnamritaprashana along with satvavajaya chikitsa is effective in reducing the signs and symptoms of Shayyamutra.

Hyperglycemia Induced by COVID-19 with and without Present Diabetes: A Systematic Review

2021 ◽  
Vol 2 (2) ◽  
pp. 64-74
Author(s):  
Gembong Satria Mahardhika
Keyword(s):  
Diabetes Mellitus ◽  
Glucose Level ◽  
High Glucose ◽  
Cell Structure ◽  
Host Cells ◽  
Google Scholar ◽  
Morbidity Rate ◽  
Mortality And Morbidity ◽  
Glucose Levels ◽  
English Manuscript

Abstract—COVID-19 is a major emerging disease that affects any certain condition. However, a recent report suggests the occurrence of hyperglycemia without any present diabetes in COVID-19 patients. This study aimed to systematically review recent evidence on hyperglycemia in COVID-19 patients. Literature research was done using four search engines, consist of Google Scholar, PubMed, ScienceDirect, and ProQuest, and limited to English manuscript only and published from February 2020 to September 2020. SARS-CoV-2 could damage the pancreas by causing the destruction of the β-cell structure that leads to impairment of glucose metabolism and worsen pre-existing diabetes or determine the appearance of hyperglycemia in non-diabetes. Inflammation also plays a major important role in hyperglycemia related to COVID-19.  Hyperglycemia increased the vulnerability of the lung, by promoting and facilitating the entry of the SARS-CoV-2 into the host cells, and decreasing lung function. Moreover, the mortality and morbidity rate conceivable increased due to hyperglycemia. The presence of high glucose levels is linked with the progression of COVID-19 severity. Thus, the glucose level should be concerned, either in a patient with present diabetes or without any presence of diabetes. Examination and monitoring of glucose levels might be a useful tool to prevent the seriousness of COVID-19 Keywords: diabetes mellitus, SARS-CoV-2, high glucose level, pulmonary infection   Abstrak—COVID-19 adalah penyakit yang muncul yang mempengaruhi kondisi  tertentu.Namun, sebuah laporan baru-baru ini menunjukkan terjadinya hiperglikemia tanpa adanya diabetes pada pasien COVID-19. Penelitian ini bertujuan untuk meninjau secara sistematis bukti terbaru tentang hiperglikemia pada pasien COVID-19. Penelitian literatur dilakukan dengan menggunakan empat mesin pencari, yaitu Google Scholar, PubMed, ScienceDirect, dan ProQuest, dan terbatas hanya pada manuskrip berbahasa Inggris dan diterbitkan dari Februari 2020 hingga September 2020. SARS-CoV-2 dapat merusak pankreas dengan menyebabkan kerusakan pada pankreas. struktur sel β yang menyebabkan gangguan metabolisme glukosa dan memperburuk diabetes yang sudah ada sebelumnya atau menentukan munculnya hiperglikemia pada kelompok non-diabetes. Peradangan juga memainkan peran penting utama dalam hiperglikemia terkait COVID-19. Hiperglikemia meningkatkan kerentanan paru-paru, dengan mendorong dan memfasilitasi masuknya SARS-CoV-2 ke dalam sel inang, dan menurunkan fungsi paru-paru. Selain itu, angka mortalitas dan morbiditas yang diperkirakan meningkat karena hiperglikemia. Adanya kadar glukosa yang tinggi dikaitkan dengan perkembangan keparahan COVID-19. Dengan demikian, kadar glukosa harus diperhatikan, baik pada pasien dengan diabetes saat ini atau tanpa adanya diabetes. Pemeriksaan dan pemantauan kadar glukosa mungkin menjadi alat yang berguna untuk mencegah derajat keparahan COVID-19. Kata kunci: diabetes mellitus, SARS-CoV-2, peningkatan kadar glukosa, infeksi paru

scholarly journals A CLINICAL STUDY ON THE EFFECTIVENESS OF AVARTHAKI CHOORNA IN PRAMEHA W.S.R. TO DIABETES MELLITUS

2020 ◽  
pp. 1-8
Author(s):  
Krishnan Mooss E.T ◽  
Veerakumara K ◽  
G Shrinivasa Acharya
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Clinical Study ◽  
Large Population ◽  
P Value ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Single Blind ◽  
Positive Results

With a prevalence rate of 424.9 million globally and 72.9 million in India, the disease Diabetes Mellitus affects a large population in our society. The prospective understanding of this disease from etiology to complication is when understood, retrospective analysis of the same in Ayurvedic perspective is characterized by Prabhoota and Avila Mootrata due to the accumulation of excess Medas in Basti leading to Prameha. The same can be understood by the theory of Osmtic diuresis in Diabetes Mellitus. The drug Virapreeta Lajjalu explained in Rajanighantu is used in the study, which has direct reference for Prameha and has not been evaluated yet. Aim: To assess the effectiveness of Avarthakichoorna in the management of Prameha w.s.r to Diabetes Mellitus and to evaluate the quality of life. Materials and Methods: A single blind clinical study where 21 patients were given the Avarthaki Choorna for a period of 14 days. Observation and Results: The statistical analysis of study revealed that the intervention was beneficial in Prabhoota Mootrata with a p value <0.001 and for Avila Mootrata it was clinically observed even though the p value 0.008. The blood glucose levels FBS and PPBS was also improved with a p value <0.001 for both. The life style assessment did also seem to be giving positive results with a p value <0.001. Conclusion: The drug Avarthaki Choorna was found to be effective in treating the Diabetes Mellitus or Prameha in terms of subjective and objective parameters. It also improves the lifestyle of a person.

A Clinical Study to evaluate Pragbhakta and Adhobhakta Bhaishajya Kala in Janu Sandhigata Vata

2019 ◽  
Vol 4 (04) ◽  
Author(s):  
Yamuna S. Reddy ◽  
K Savitha R. Shenoy ◽  
Sri Nagesh KA
Keyword(s):  
Clinical Trial ◽  
Statistical Analysis ◽  
Clinical Study ◽  
Treatment Success ◽  
Signs And Symptoms ◽  
Therapeutic Effects ◽  
Important Principle ◽  
Group A ◽  
Group B

Bhaishajya Kala is an important principle in our classics, which is to be considered while treating a disease. During treatment, success can be achieved only when there is proper combination of Desha, Kala, Pramana, Satmya, Asatmya, Pathya and Apathya. [1] Among these seven, Kala is given second position which reflects importance of Kala in Chikitsa. The relation between Aushadha and Kala is well established in classics. Acharya Charaka states that “medicine administered at appropriate Kala is more efficacious than one given in inappropriate Kala. ”[2] To highlight its role in Chikitsa, there is a necessity to analyze this concept which is the need of the hour. With the intention of practically validating this concept “Janu Sandhigatavata” has been taken up for the study. Panchatikta Guggulu Ghrita which has been taken for the study is seen to have beneficial therapeutic effects on Sandhigatavata as evidently seen in the Phalashruti. [3] As Bhaishajya Kala is not specifically mentioned for any Vatavyadhi so also for Janu Sandhigatavata, this study intends to find the appropriate Bhaishajya Kala for the same. Among all the Bhaishajya Kalas, in the present study only two Kalas were taken up which were suitable for Janu Sandhigatavata. The clinical trial was carried out on 40 patients. They were divided into two groups Group A and Group B consisting of 20 patients each. The results were analyzed based on the signs and symptoms. Statistical analysis between Group A and Group B for the parameters Sandhi Shoola, Shotha, Prasaranaakunchanyo Vedana, ROM and VAS painscale found no significant changes in the group. Individually each Group had highly significant results. But in the observation parameter of Atopa there was a difference of value between the groups, Group A was higher than Group B.

scholarly journals Assessment Strategies to Improve the Diagnosis of Osteomyelitis in Diabetic Foot Using Radiography

2018 ◽  
Vol 1 (06) ◽  
pp. 34-36
Author(s):  
Jose Maria Pereira De Godoy
Keyword(s):  
Diabetes Mellitus ◽  
Clinical Trial ◽  
Diabetic Foot ◽  
Diabetic Patients ◽  
Bone Surface ◽  
Bacterial Cultures ◽  
System Disease ◽  
Diagnostic Window ◽  
Assessment Strategies ◽  
Positive Results

Background:  Diabetes mellitus is a multi-system disease that affects people of both genders and any age or ethnic group. Foot wounds are common and can lead to loss of limb in cases of therapeutic failure. Aim: The aim of this study was to correlate initial diagnoses of osteomyelitis by radiography with bacterial cultures and identify ways to improve the diagnosis using this method. Method: In a prospective random clinical trial, the correlation between radiographs and bacterial cultures were evaluated in diabetic patients undergoing amputation of toes or part of the foot in Hospital de Base in the period from October 2010 to January 2012. Radiographs were considered suggestive of osteomyelitis if they identified an irregular bone surface, obliteration, bone resorption or periosteal resorption. The diagnostic impression from imaging was compared to the results of a bacterial growth culture prepared using bone removed during surgery. Results: An analysis of the radiographs identified 29 patients with results that were suggestive of osteomyelitis. Of these, the results of 27 bacterial cultures were positive. Eight of the 22 radiographs that were not suggestive of osteomyelitis were negative and 14 were positive. Conclusion: The diagnosis of osteomyelitis in diabetic foot can be improved by stratifying the results, taking the positive results and creating a diagnostic window with another diagnostic evaluation in cases that are initially negative.

Development of clinical trial guideline for Diabetes Mellitus on traditional Korean medicines

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
JH Baek ◽  
JP Lee ◽  
JY Park ◽  
JH Lee ◽  
CH Cho ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Clinical Trial

Drug-Induced Agranulocytosis: A Mini Review

2016 ◽  
Vol 2 (1) ◽  
pp. 57-59
Author(s):  
Pavithra D ◽  
Praveen D ◽  
Vijey Aanandhi M
Keyword(s):  
Bone Marrow ◽  
Complete Blood Count ◽  
Genetic Manipulation ◽  
White Blood Cells ◽  
Deep Infection ◽  
Morbidity Rate ◽  
Drug Induced ◽  
Serious Adverse Event ◽  
Mortality And Morbidity ◽  
The Individual

Agranulocytosis is also known to be granulopenia, causing neutropenia in circulating blood streams .The destruction of white blood cells takes place which leads to increase in the infection rate in an individual where immune system of the individual is suppressed. The symptoms includes fever, sore throat, mouth ulcers. These are commonly seen as adverse effects of a particular drug and are prescribed for the common diagnostic test for regular monitoring of complete blood count in an admitted patient. Drug-induced agranulocytosis remains a serious adverse event due to occurrence of severe sepsis with deep infection leading to pneumonia, septicaemia, and septic shock in two/third of the patient. Antibiotics seem to be the major causative weapon for this disorder. Certain drugs mainly anti-thyroid drugs, ticlopidine hydrochloride, spironolactone, clozapine, antileptic drugs (clozapine), non-steroidal anti-inflammatory agents, dipyrone are the potential causes. Bone marrow insufficiency followed by destruction or limited proliferative bone marrow destruction takes place. Chemotherapy is rarely seen as a causative agent for this disorder. Genetic manipulation may also include as one of the reason. Agranulocytosis can be recovered within two weeks but the mortality and morbidity rate during the acute phase seems to be high, appropriate adjuvant treatment with broad-spectrum antibiotics are prerequisites for the management of complicated neutropenia. Drugs that are treated for this are expected to change as a resistant drug to the patient. The pathogenesis of agranulocytosis is not yet known. A comprehensive literature search has been carried out in PubMed, Google Scholar and articles pertaining to drug-induced agranulocytosis were selected for review.

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