The use of magnetic nanoparticles for immobilization and recycling of enzymes

MRS Advances ◽  
2018 ◽  
Vol 3 (61) ◽  
pp. 3581-3587
Author(s):  
Shirley Furtado ◽  
Mariana Brandes ◽  
Catalina Alamón ◽  
Santiago Botasini ◽  
Ana M.B. Cantera
Keyword(s):  
Magnetic Nanoparticles ◽  
Surface Area ◽  
Nanostructured Materials ◽  
Enzyme Immobilization ◽  
Proteolytic Enzymes ◽  
Large Surface Area ◽  
Emergent Properties ◽  
Initial Activity ◽  
Enzyme Adsorption

ABSTRACTThe use of nanostructured materials for enzyme immobilization is an active field of research due to its large surface area and the new emergent properties derived from its size. The present work is focused on the synthesis of magnetic nanoparticles for the adsorption of cysteine-proteolytic enzymes extracted from Bromelia antiacantha Bertol (Bromeliaceae) fruit. The results show that enzyme adsorption is highly dependent on the temperature and pH. The biocatalyst activity increased up to 40 %, once immobilized onto the magnetic nanoparticles. In addition, they can be recovered using a magnet allowing them to be reused up to 5 cycles with a marginal loss (5 %) of the initial activity.

A simple and low-cost route to recycle rare earth elements (La, Ce) from aqueous solution using magnetic nanoparticles of CoxMn1−xFe2O4 (x = 0.2 and 0.8): synthesis, isotherms, kinetics, thermodynamics and desorption

2017 ◽  
Vol 41 (20) ◽  
pp. 11906-11914 ◽  
Author(s):  
Misagh Ghobadi ◽  
Mahdi Gharabaghi ◽  
Hadi Abdollahi ◽  
Amir Shafiee Kisomi
Keyword(s):  
Aqueous Solution ◽  
Rare Earth ◽  
Magnetic Nanoparticles ◽  
Rare Earth Elements ◽  
Surface Area ◽  
Low Cost ◽  
Large Surface Area

Magnetic nanoparticles of CoxMn1−xFe2O4 with a large surface area have been developed for REE cations adsorption.

Functional Two-Dimensional Black Phosphorus Nanostructures towards Next-Generation Devices

2021 ◽  
Author(s):  
Mengke Wang ◽  
Jun Zhu ◽  
You Zi ◽  
Zheng-Guang Wu ◽  
Haiguo Hu ◽  
...  
Keyword(s):  
Surface Area ◽  
Biomedical Applications ◽  
Black Phosphorus ◽  
Large Surface Area ◽  
Two Dimensional ◽  
Next Generation

In recent years, two-dimensional (2D) black phosphorus (BP) has been widely applied in many fields, such as (opto)electronics, transistors, catalysis and biomedical applications due to its large surface area, tunable...

Research on metallic chalcogen-functionalized monolayer-puckered V2CX2 (X = S, Se, and Te) as promising Li-ion battery anode materials

2021 ◽  
Author(s):  
Chunmei Tang ◽  
Xiaoxu Wang ◽  
Shengli Zhang
Keyword(s):  
Surface Area ◽  
Anode Materials ◽  
Large Surface Area ◽  
Two Dimensional ◽  
Li Ion Batteries ◽  
Li Ion Battery ◽  
Li Ion ◽  
Battery Anode

Two-dimensional MXene nanomaterials are promising anode materials for Li-ion batteries (LIBs) due to their excellent conductivity, large surface area, and high Li capability.

scholarly journals Strategic use of nanotechnology in drug targeting and its consequences on human health: A focused review

2019 ◽  
Vol 11 (1) ◽  
pp. 38-54 ◽  
Author(s):  
Anand Maurya ◽  
Anurag Kumar Singh ◽  
Gaurav Mishra ◽  
Komal Kumari ◽  
Arati Rai ◽  
...  
Keyword(s):  
Human Health ◽  
Surface Area ◽  
Medical Diagnosis ◽  
Drug Targeting ◽  
Pharmaceutical Market ◽  
Large Surface Area ◽  
Mass Ratio ◽  
Disease Therapy ◽  
Significant Interest ◽  
Medical Benefits

Since the development of first lipid-based nanocarrier system, about 15% of the present pharmaceutical market uses nanomedicines to achieve medical benefits. Nanotechnology is an advanced area to meliorate the delivery of compounds for improved medical diagnosis and curing disease. Nanomedicines are gaining significant interest due to the ultra small size and large surface area to mass ratio. In this review, we discuss the potential of nanotechnology in delivering of active moieties for the disease therapy including their toxicity evidences. This communication will help the formulation scientists in understanding and exploring the new aspects of nanotechnology in the field of nanomedicine.

Synthesis of functional hollow WS2 particles with large surface area for Near-Infrared (NIR) triggered drug delivery

2021 ◽  
Vol 875 ◽  
pp. 160034
Author(s):  
Na Liu ◽  
Fan Fan ◽  
Wei Xu ◽  
Hao Zhang ◽  
Qi Zhou ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Surface Area ◽  
Near Infrared ◽  
Large Surface Area

Physico-Chemical and Morphological Changes of Sayong Kaolinite Clay Treated with Sulphuric Acid for Enzyme Immobilization

2013 ◽  
Vol 832 ◽  
pp. 589-595 ◽  
Author(s):  
N.A. Edama ◽  
A. Sulaiman ◽  
K.H. Ku Hamid ◽  
M.N. Muhd Rodhi ◽  
Mohibah Musa ◽  
...  
Keyword(s):  
Surface Area ◽  
Sulphuric Acid ◽  
Enzyme Immobilization ◽  
Morphological Changes ◽  
Chemical Properties ◽  
X Ray Diffraction ◽  
Kaolinite Clay ◽  
X Ray ◽  
Mineral Oxides ◽  
Physico Chemical

This study analyzed the effects of sulphuric acid (H2SO4) treatment on pysico-chemical properties and morphological changes of clay obtained from Sg. Sayong, Perak. The clay was ground and sieved to <150μm and treated with different concentrations of H2SO4. The treatment was completed by refluxing the clay with different concentration of H2SO4 (1M, 5M and 10M ) at 100 °C for 4 hours and followed by calcination at 500 °C for 1 hour. The physic-chemical properties and morphological changes of the untreated and treated clay were compared using Surface Area Analyser, X-Ray Diffraction (XRD), Field Emission Scanning Electron Micrograph (FESEM), X-Ray Diffraction (XRD) and Fourier Transformed Infrared Spectroscopy (FTIR). The results showed that acid treatment of 5M increased the surface area from 25 m2/g to 75 m2/g and the pore volume increased from 0.1518 cc/g to 0.3546 cc/g. The nanopore size of the clay decreased from 24.8 nm to 19.4 nm after treated with acid. This can be explained due to the elimination of the exchangeable cations and generation of microporosity. The results of XRF showed SiO2 increased from 58.34% to 74.52% and Al2O3 reduced from 34.6% to 18.31%. The mineral oxides such as Fe2O3, MgO, CaO, K2O and TiO2 also reduced. This concluded that H2SO4 treatment has led to significant removal of octahedral Al3+, Fe3+ cations and other impurities. In conclusion, this study showed the physico-chemical properties and morphology of Sayong clay were improved once treated with H2SO4 and therefore suggests better supporting material for enzyme immobilization.

Accelerating ion diffusion with unique three-dimensionally interconnected nanopores for self-membrane high-performance pseudocapacitors

Nanoscale ◽  
2017 ◽  
Vol 9 (46) ◽  
pp. 18311-18317 ◽  
Author(s):  
Yuan Gao ◽  
Yuanjing Lin ◽  
Zehua Peng ◽  
Qingfeng Zhou ◽  
Zhiyong Fan
Keyword(s):  
Aspect Ratio ◽  
Surface Area ◽  
Structural Stability ◽  
High Aspect Ratio ◽  
High Performance ◽  
Three Dimensional ◽  
Rate Capability ◽  
Large Surface Area ◽  
Nanoporous Structure ◽  
Ion Diffusion

Three-dimensional interconnected nanoporous structure (3-D INPOS) possesses high aspect ratio, large surface area, as well as good structural stability. Profiting from its unique interconnected architecture, the 3-D INPOS pseudocapacitor achieves a largely enhanced capacitance and rate capability.

Transport of Ions and Molecules in Nanofluidic Devices

2008 ◽  
Author(s):  
Rohit Karnik ◽  
Chuanhua Duan ◽  
Kenneth Castelino ◽  
Rong Fan ◽  
Peidong Yang ◽  
...  
Keyword(s):  
Surface Charge ◽  
Surface Area ◽  
Field Effect ◽  
Electrostatic Interactions ◽  
Surface Reactions ◽  
Molecular Transport ◽  
Large Surface Area ◽  
Ionic Concentrations ◽  
Nanofluidic Devices ◽  
Transport Of Ions

Interesting transport phenomena arise when fluids are confined to nanoscale dimensions in the range of 1–100 nm. We examine three distinct effects that influence ionic and molecular transport as the size of fluidic channels is decreased to the nanoscale. First, the length scale of electrostatic interactions in aqueous solutions becomes comparable to nanochannel size and the number of surface charges becomes comparable to the number of ions in the channel. Second, the size of the channel becomes comparable to the size of biomolecules such as proteins and DNA. Third, large surface area-to-volume ratios result in rapid rates of surface reactions and can dramatically affect transport of molecules through the channel. These phenomena enable us to control transport of ions and molecules in unique ways that are not possible in larger channels. Electrostatic interactions enable local control of ionic concentrations and transport inside nanochannels through field effect in a nanofluidic transistor, which is analogous to the metal-oxide-semiconductor field effect transistor. Furthermore, by controlling surface charge in nanochannels, it is possible to create a nanofluidic diode that rectifies ionic transport through the channel. Biological binding events result in partial blockage of the channel, and can thus be sensed by a decrease in nanochannel conductance. At low ionic concentrations, the effect of biomolecular charge is dominant and it can lead to an increase in conductance. Surface reactions can also be used to control transport of molecules though the channel due to the large surface area-to-volume ratios. Rapid surface reactions enable a new technique of diffusion-limited patterning (DLP), which is useful for patterning of biomolecules and surface charge in nanochannels. These examples illustrate how electrostatic interactions, biomolecular size, and surface reactions can be used for controlling ionic and molecular transport through nanochannels. These phenomena may be useful for operations such as analyte focusing, pH and ionic concentration control, and biosensing in micro- and nanofluidic devices.

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