Low Skeletal Bone Mineral Density Does Not Affect Dental Implants

2015 ◽  
Vol 41 (5) ◽  
pp. 550-553 ◽  
Author(s):  
Pouran Famili ◽  
Jennifer M. Zavoral

The aim of this case-control study (n = 30) was to evaluate the effects of osteoporosis/osteopenia on the success of dental implants. Twenty healthy females ages 50–80 with confirmed osteoporosis or osteopenia, and 10 age- and gender-matched subjects with normal bone density (controls) received dental implants. Dual-energy X-ray absorptiometry (DXA) scans at 5 standard sites (total body, hip, spine [lateral and anterior-posterior] and radius) were measured at baseline and 24 months. Periapical and panoramic radiographs were taken at baseline before implant placement; 1 periapical radiograph was taken immediately after placement of the dental implant. Since implants are standard sizes, periapical bone loss was measured from the first implant thread to the level of alveolar bone at baseline, 12 months, and 24 months via 1 periapical radiograph. All subjects received implants of the same manufacturer (NobelBiocare). One subject was a smoker. Three subjects with osteoporosis had received prior treatment with Fosamax, 1 received Fortical, and 1 Forteo. In all 3, there was slight improvement in DXA after 24 months. All implants remained successful with no evidence of bone loss after 24 months. These investigators conclude that implants placed in individuals with confirmed skeletal osteoporosis can be successful, with no clinical differences to implants placed in healthy individuals. Although 3 subjects with osteoporosis had treatment with oral bisphosphonates, no side effects were noted and no bone necrosis of the jaw was observed. Further investigation with larger sample sizes and longer periods of time for treatment with oral bisphosphonates is recommended to confirm these results.

2020 ◽  
Vol 4 (Supplement_1) ◽  
Author(s):  
Lisa Marie Yerke ◽  
Robert E Cohen

Abstract Introduction: Hypothyroidism (HT) is an endocrine condition with autoimmune and inflammatory etiologies. Studies have shown that both periodontal disease and peri-implant bone loss are bidirectionally influenced by systemic inflammatory conditions, such as diabetes, adverse pregnancy outcomes, cardiovascular disease, and osteoporosis.1 There also is evidence that HT is associated with decreased bone metabolism, depressed bone turnover, and a prolonged bone remodeling cycle.2 Consequently, the objective of this study was to determine if the severity of bone loss around dental implants is related to the presence of HT. Methods: Following IRB approval, medical, dental, and radiographic records of patients who received dental implant placement at a university-based postgraduate program in periodontics from 2000–2017 were reviewed (1480 implants; 635 patients). Rate of bone loss in mm/year was calculated from surgical implant placement and subsequent re-evaluation radiographs, with correction for radiographic distortion. Presence of HT was confirmed by review of patient medical records, clinical diagnosis of HT, and history of thyroid hormone supplementation. Populations were adjusted for smoking, diabetes, use of systemic steroids, presence of autoimmune disease (other than HT), and systemic inflammatory conditions. Calculations were performed using IBM SPSS Statistics v25. Results: Patients with HT had a decreased rate of crestal alveolar bone loss around dental implants. Specifically, patients with HT experienced peri-implant bone loss at a rate of 0.42 mm/year, while bone loss from patients without HT was 1.34 mm/year (68.7% decrease; mean difference = 0.92 mm/year, 95% confidence interval = 0.39–1.50 mm/year, P<0.002). There were no significant differences in patient oral hygiene, or in implant service time, among any of the groups studied (P>0.05). Conclusions: The results suggest that the rate of marginal alveolar bone loss at dental implants is significantly decreased in patients with HT, and occurs independently of any of the systemic conditions noted above. The findings imply that potential changes in bone metabolism and remodeling associated with HT might result in less peri-implant alveolar bone loss following implant placement surgery. As a result, there does not appear to be an increased risk of peri-implant crestal bone loss in patients with HT. References: 1Kim J., Amar S., Odontol. 94(1):10–21, 2006. 2Tuchendler D., and Bolanowski M.,Thyroid Res. 7:12, 2014.


2018 ◽  
Vol 28 (2) ◽  
pp. 109-114 ◽  
Author(s):  
Tuba Talo Yildirim ◽  
Güliz Nigar Güncü ◽  
Mehmet Colak ◽  
Tolga Fikret Tözüm

Objectives: Sinus floor elevation and augmentation surgery is widely used as a reliable procedure to increase insufficient bone height in the posterior maxillary area. The purpose of the present clinical study was to determine the associations between periodontal bone loss (PBL), maxillary sinus lateral bone wall thickness, age, and gender using cone-beam computerized tomography (CBCT). Materials and Methods: The current retrospective study consists of 716 maxillary sinus CBCT images of 358 patients. The CBCT scans were assessed to detect the relationship between lateral wall thickness and PBL. ANOVA and Student t test analysis were used to determine the influence of PBL on sinus lateral wall thickness. Results: Sinus lateral wall thickness was significantly associated with PBL (p < 0.05) at 3, 13, and 15 mm height. There was no significant association between lateral wall thickness and gender (p > 0.05). However, there was a significant association between lateral wall thickness at 3 and 13 mm and age (p < 0.05). There were significant associations between PBL and age (p < 0.001), and PBL and gender (p < 0.05). Conclusions: PBL might have an association with maxillary sinus lateral bone wall thickness. Further studies are needed to confirm this possible relationship.


2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Vadims Klimecs ◽  
Alexanders Grishulonoks ◽  
Ilze Salma ◽  
Laura Neimane ◽  
Janis Locs ◽  
...  

Biphasic calcium phosphate ceramic granules (0.5–1.0 mm) with a hydroxyapatite and β-tricalcium phosphate ratio of 90/10 were used. Biphasic calcium phosphate ceramic granules produced in the Riga Technical University, Riga Rudolph Cimdins Biomaterials Innovation and Development Centre, were used for filling the bone loss on 18 patients with peri-implantitis. After 5 years at the minimum, clinical and 3D cone-beam computed tomography control was done. Clinical situation confirmed good stability of implants without any signs of inflammation around. Radiodensity of the previous gap and alveolar bone horizontally from middle point of dental implants showed similar radiodensity as in normal alveolar bone. This trial is registered with ISRCTN13514478.


2015 ◽  
Vol 112 (48) ◽  
pp. 14972-14977 ◽  
Author(s):  
Sofia Movérare-Skrtic ◽  
Jianyao Wu ◽  
Petra Henning ◽  
Karin L. Gustafsson ◽  
Klara Sjögren ◽  
...  

Wingless-type MMTV integration site family (WNT)16 is a key regulator of bone mass with high expression in cortical bone, and Wnt16−/− mice have reduced cortical bone mass. As Wnt16 expression is enhanced by estradiol treatment, we hypothesized that the bone-sparing effect of estrogen in females is WNT16-dependent. This hypothesis was tested in mechanistic studies using two genetically modified mouse models with either constantly high osteoblastic Wnt16 expression or no Wnt16 expression. We developed a mouse model with osteoblast-specific Wnt16 overexpression (Obl-Wnt16). These mice had several-fold elevated Wnt16 expression in both trabecular and cortical bone compared with wild type (WT) mice. Obl-Wnt16 mice displayed increased total body bone mineral density (BMD), surprisingly caused mainly by a substantial increase in trabecular bone mass, resulting in improved bone strength of vertebrae L3. Ovariectomy (ovx) reduced the total body BMD and the trabecular bone mass to the same degree in Obl-Wnt16 mice and WT mice, suggesting that the bone-sparing effect of estrogen is WNT16-independent. However, these bone parameters were similar in ovx Obl-Wnt16 mice and sham operated WT mice. The role of WNT16 for the bone-sparing effect of estrogen was also evaluated in Wnt16−/− mice. Treatment with estradiol increased the trabecular and cortical bone mass to a similar extent in both Wnt16−/− and WT mice. In conclusion, the bone-sparing effects of estrogen and WNT16 are independent of each other. Furthermore, loss of endogenous WNT16 results specifically in cortical bone loss, whereas overexpression of WNT16 surprisingly increases mainly trabecular bone mass. WNT16-targeted therapies might be useful for treatment of postmenopausal trabecular bone loss.


1992 ◽  
Vol 82 (4) ◽  
pp. 429-432 ◽  
Author(s):  
J. E. Compston ◽  
M. A. Laskey ◽  
P. I. Croucher ◽  
A. Coxon ◽  
S. Kreitzman

1. Total body areal bone mineral density was measured by dual-energy X-ray absorptiometry in eight women before and 10 weeks after a very-low-calorie diet [405 kcal (1701 kJ)/day]. 2. The mean weight loss of 15.6 kg was accompanied by a statistically significant reduction in total body bone mineral density from 1.205 ± 0.056 to 1.175 ± 0.058 g/cm2 (mean ± sd, P < 0.005). 3. After cessation of the diet, weight gradually increased and by 10 months was similar to baseline values. Total body bone mineral density also increased after stopping the diet and mean values obtained 10 months after the diet did not differ significantly from initial values. Throughout the study total body bone mineral density values in all subjects were well within the range reported for normal subjects. 4. These data indicate that diet-induced weight loss is associated with rapid bone loss, subsequent weight gain being accompanied by increases in bone mass. Further studies are required to establish the clinical significance of these findings and, in particular, the skeletal distribution of bone loss.


2020 ◽  
Vol 11 (SPL3) ◽  
pp. 358-362
Author(s):  
Rinieshah Nair R Baskran ◽  
Rajendra Prabhu Abhinav ◽  
Murugaiyan Arun ◽  
Balaji Ganesh S

Dental implants provide a strong foundation for fixed or removable prosthetic teeth that are made to match natural dentition. It has become an ideal method of oral rehabilitation after missing natural dentition has been recognised as a reliable tool for dental reconstruction and aesthetics. Marginal bone loss is characterized by a reduction in bone loss is characterized by a reduction in bone level both vertically and horizontally. The levels at which dental implants are placed include sub-crystal, equi-crestal, and supra-crestal. The crestal levels affect bone height significantly. Failure to do so will lead to peri-implant bone loss which will affect the implant function and ultimately implant failure. A retrospective study was conducted based on a university setting. 615 patients with 1141 implant sites were reviewed from June 2019 to March 2020. Excel tabulation and SPSS analysis were done for data analysis. There was a statistically significant difference between the variables that included tooth region, crestal relation and site (jaw)—[p-value<0.05] The most common crestal relation of implant placement is equi-crestal implant placement. The assessment of trends of implant placement in relation to crestal bone level shows that equi-crestal implant is the most preferred crestal relation of implant placement in Saveetha Dental College.


2019 ◽  
Vol 104 (8) ◽  
pp. 3576-3584 ◽  
Author(s):  
Sarah M Bristow ◽  
Anne M Horne ◽  
Greg D Gamble ◽  
Borislav Mihov ◽  
Angela Stewart ◽  
...  

Abstract Context Calcium intakes are commonly lower than the recommended levels, and increasing calcium intake is often recommended for bone health. Objective To determine the relationship between dietary calcium intake and rate of bone loss in older postmenopausal women. Participants Analysis of observational data collected from a randomized controlled trial. Participants were osteopenic (hip T-scores between −1.0 and −2.5) women, aged >65 years, not receiving therapy for osteoporosis nor taking calcium supplements. Women from the total cohort (n = 1994) contributed data to the analysis of calcium intake and bone mineral density (BMD) at baseline, and women from the placebo group (n = 698) contributed data to the analysis of calcium intake and change in BMD. BMD and bone mineral content (BMC) of the spine, total hip, femoral neck, and total body were measured three times over 6 years. Results Mean calcium intake was 886 mg/day. Baseline BMDs were not related to quintile of calcium intake at any site, before or after adjustment for baseline age, height, weight, physical activity, alcohol intake, smoking status, and past hormone replacement use. There was no relationship between bone loss and quintile of calcium intake at any site, with or without adjustment for covariables. Total body bone balance (i.e., change in BMC) was unrelated to an individuals’ calcium intake (P = 0.99). Conclusions Postmenopausal bone loss is unrelated to dietary calcium intake. This suggests that strategies to increase calcium intake are unlikely to impact the prevalence of and morbidity from postmenopausal osteoporosis.


Author(s):  
Soundariya Bala Muralei

Long-term stability of a dental implant depends on various factors, one among them is proper position within the alveolar bone. Pre-operative thorough examination of the surgical site is preliminary step while planning dental implants. Conventional techniques such as Intra-Oral Periapical Radiograph and Ortho Pantamogram sometimes not sufficient and clinical scenario always surprises the surgeon. Later advent of Cone-Beam Computed Tomography alleviated this problem to some extent but there are some clinical situations such as resorbed ridge where better visualisation is needed. This led to the innovation of rapid prototyping techniques for the fabrication of three-dimensional complex structures. This technology has numerous applications from the development of an instrument, 3-D printed anatomical models to the fabrication of 3-D printed tissues for regeneration procedures. A 3-D printed model is much more useful than plaster models in many aspects such as demonstrating anatomical structures, better treatment planning, and better understanding for the patient. Hence, this case series focuses on the use of 3-D printed models in the placement of dental implants.


Author(s):  
Getúlio Batista de Oliveira ◽  
◽  
Mariana de Almeida Basilio ◽  
Nara Santos Araujo ◽  
Patricia Ramos Cury ◽  
...  

For a long time, different approaches to minimize the dimensional ridge alteration following tooth extraction have been described even though none of them was capable to avoid alveolar bone loss. The Socket-Shield Technique (SST) seems to be an alternative for alveolar bone preservation in dental extraction planning. This technique conventionally uses a flapless approach and the buccal root portion retention to prevent bone loss. This case report describes the SST with an early implant placement in a patient who presented the nonrestorable tooth # 15 due to the extensive cavity. After six months of the implant placement a porcelain-fused-to-metal crown was fabricated and screwed into the implant with a satisfactory esthetic and functional result. The SST is a non-invasive and effective approach to tooth extraction and rehabilitation, especially in the aesthetic zone. Approximately two-year follow-up shows a satisfactory aesthetic maintenance.


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