Effects of red wine on established markers of arterial structure and function in human studies: current knowledge and future research directions

2013 ◽  
Vol 6 (6) ◽  
pp. 613-625 ◽  
Author(s):  
Arduino A Mangoni ◽  
Creina S Stockley ◽  
Richard J Woodman
ExRNA ◽  
2019 ◽  
Vol 1 (1) ◽  
Author(s):  
Fangfang Jin ◽  
Zhigang Guo

Abstract The discovery of small non-coding RNAs, such as miRNA and piRNA, has dramatically changed our understanding of the role RNA plays in organisms. Recent studies show that a novel small non-coding RNA generated from cleavage of tRNA or pre-tRNA, called tRNA-derived small RNA (tsRNA), serves as a new regulator of gene expression. tsRNA has been determined participate in regulating some specific physiological and pathological processes. Although knowledge regarding the biological roles of miRNA and piRNA is expanding, whether tsRNAs play similar roles remains poorly understood. Here, we review the current knowledge regarding the mechanisms of action and biological functions of tsRNAs in intracellular, extracellular and intergenerational inheritance, and highlight the potential application of tsRNAs in human diseases, and present the current problems and future research directions.


2021 ◽  
Vol 5 ◽  
Author(s):  
Zixin Zhang ◽  
Yang Zhang

Abstract Melatonin is an endogenous micromolecular compound of indoleamine with multiple physiological functions in various organisms. In plants, melatonin is involved in growth and development, as well as in responses to biotic and abiotic stresses. Furthermore, melatonin functions in phytohormone-mediated signal transduction pathways. There are multiple melatonin biosynthesis pathways, and the melatonin content in plants is greatly affected by intrinsic genetic characteristics and external environmental factors. Although melatonin biosynthesis has been extensively studied in model plants, it remains uncharacterized in most plants. This article focuses on current knowledge on the biosynthesis, regulation and application of melatonin, particularly for fruit quality and preservation. In addition, it highlights the links between melatonin and other hormones, as well as future research directions.


2020 ◽  
Vol 13 (3) ◽  
pp. 795-848
Author(s):  
Alina Köchling ◽  
Marius Claus Wehner

AbstractAlgorithmic decision-making is becoming increasingly common as a new source of advice in HR recruitment and HR development. While firms implement algorithmic decision-making to save costs as well as increase efficiency and objectivity, algorithmic decision-making might also lead to the unfair treatment of certain groups of people, implicit discrimination, and perceived unfairness. Current knowledge about the threats of unfairness and (implicit) discrimination by algorithmic decision-making is mostly unexplored in the human resource management context. Our goal is to clarify the current state of research related to HR recruitment and HR development, identify research gaps, and provide crucial future research directions. Based on a systematic review of 36 journal articles from 2014 to 2020, we present some applications of algorithmic decision-making and evaluate the possible pitfalls in these two essential HR functions. In doing this, we inform researchers and practitioners, offer important theoretical and practical implications, and suggest fruitful avenues for future research.


Pedobiologia ◽  
2016 ◽  
Vol 59 (3) ◽  
pp. 129-174 ◽  
Author(s):  
Charlene Janion-Scheepers ◽  
John Measey ◽  
Brigitte Braschler ◽  
Steven L. Chown ◽  
Louise Coetzee ◽  
...  

2021 ◽  
Vol 15 ◽  
Author(s):  
Nounagnon Frutueux Agbangla ◽  
Pauline Maillot ◽  
Damien Vitiello

The cardiorespiratory hypothesis (CH) is one of the hypotheses used by researchers to explain the relationship between cardiorespiratory fitness and cognitive performance during executive functions. Despite the indubitable beneficial effect of training on brain blood flow and function that may explain the link between physical fitness and cognition and the recognition of the near-infrared spectroscopy (NIRS) as a reliable tool for measuring brain oxygenation, few studies investigated the CH with NIRS. It is still not well understood whether an increase in brain flow by training is translated into an increase in cerebral oxygenation. Thus, the objective of this mini-review was to summarize main results of studies that investigated the CH using the NIRS and to propose future research directions.


2021 ◽  
Vol 3 (3) ◽  
pp. 85-110
Author(s):  
Jildau Borwell ◽  
Jurjen Jansen ◽  
Wouter Stol

This paper addresses the importance of building knowledge on the impact of cybercrime victimization. Because the topic is understudied, it is unclear whether the impact of cybercrime differs from that of traditional crime. Our understanding of potential impact differences needs to be improved, considering that society and criminality are digitizing and, consequently, more people are likely to become victims of cybercrime. From a practical perspective, knowledge about the impact of different crimes is important to develop victim policies within law enforcement and other relevant agencies, and to treat victims appropriately. In this paper, a literature review is provided, as well as future research directions to address the current knowledge gap. The future research directions are divided in three topics: (1) distinguishing between cybercrime and traditional crime, (2) classifying cybercrime and traditional crime, and (3) measuring the victimization impact of cybercrime and traditional crime.


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