The relationship between malnutrition and quality of life in haemodialysis and peritoneal dialysis patients

SUMMARY BACKGROUND One of the most important factors affecting the quality of life of chronic kidney disease (CKD) patients is nutrition. Prevention of malnutrition increases patients’ quality and length of life. In this study, we aimed to determine the frequency of malnutrition, quality of life, and the relationship between them in patients with end-stage renal disease (ESRD). METHOD The study was conducted with a total of 60 CKD patients including 50 haemodialysis patients and 10 peritoneal dialysis patients. Patients’ data associated with socio-demographics, body mass index (BMI), waist circumference, triceps skin-fold thickness (TSFT), pre-dialysis systolic and diastolic blood pressure, Kt/V and urea reduction ratio (URR) values, laboratory parameters, Mini-Nutritional Assessment-Short Form (MNA-SF) and European Quality of Life 5-Dimensions (EQ5D) scale were recorded. FINDINGS Of the total 60 patients; 27 were male (45%), 33 were female (55%), 83.3% were receiving haemodialysis treatment (HD), and 16.7% were receiving peritoneal dialysis treatment (PD). The mean MNA-SF score was 10.4 ± 2.8 in the HD group and 10.5 ± 2.9 in the PD group; there was no difference between the scores of the HD and PD groups. The mean EQ5D score was 0.60 ± 0.29 in the HD group and 0.68 ± 0.33 in the PD group, no significant difference was found between the HD group and the PD group. The quality of life was found lower in malnourished group (p=0.001). CONCLUSION The quality of life needs to be increased by early diagnosis and treatment of malnutrition in patients at risk.

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The Relationship of Health Literacy and General Literacy with Quality of Life among Older Adults in Bojnurd, Iran

Elderly Health Journal ◽

10.18502/ehj.v6i2.5009 ◽

2020 ◽

Author(s):

Sahel Sangsefidi ◽

Akram Ghanbari Moghaddam ◽

Safooreh Esmaielzadeh iri sofla ◽

Saeedeh Avazzade ◽

Zeinab Karbalaee ◽

...

Keyword(s):

Quality Of Life ◽

Older Adults ◽

Health Literacy ◽

Short Form ◽

Cluster Sampling ◽

Significant Difference ◽

The Mean ◽

The Relationship ◽

Score Range

Introduction: Quality of life of older adults is one of the most important issues in their health care. The aim of this study was to investigate the power of health literacy and general literacy in predicting quality of life among older adults in Bojnurd, Iran. Methods: This cross-sectional study was conducted on 180 older adults in Bojnurd city in 2016. The participants were selected by multi-stage cluster sampling method. The instruments used in this study included the demographic variables questionnaire, 12-Item Short Form Health Survey and Health Literacy for Iranian Adults. To describe and analyze the data, SPSS software was used. Descriptive statistics, Kolmogorov-Smirnov, Mann-Whitney U, ANOVA, Spearman correlation coefficient, and multifactorial regression analysis were run to analyze the data. Results: The mean health literacy score was 69.76 ± 15.05 (score range from 0 to 100) and the mean score of quality of life was 26.2 ± 6.12 (score range from 12 to 48). The level of health literacy was insufficient in 32.2% of the participants and about half of them lacked general literacy. The relationship between health literacy and quality of life was statistically significant (p < 0.001) (r = 0.54). A significant difference was observed between the illiterate and literate seniors with regard to their quality of life scores (p < 0.001). The predictive power of health literacy and general literacy was statistically significant in obtaining a higher score in quality of life with Beta coefficients of 0.65 and 0.25, respectively (p < 0.001). Conclusion: Although health literacy and general literacy affect the elderlies’ quality of life positively, health literacy is more effective. Therefore, authorities are suggested to increase their quality of health literacy to improve the seniors’ quality of life.

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Impact of Polypharmacy on Health-Related Quality of Life in Dialysis Patients

American Journal of Nephrology ◽

10.1159/000518454 ◽

2021 ◽

pp. 1-10

Author(s):

Julia M.T. Colombijn ◽

Anna A. Bonenkamp ◽

Anita van Eck van der Sluijs ◽

Joost A. Bijlsma ◽

Arnold H. Boonstra ◽

...

Keyword(s):

Quality Of Life ◽

Short Form ◽

Health Related Quality ◽

Dialysis Patients ◽

Self Rated Health ◽

Significant Difference ◽

Related Quality ◽

Health Related ◽

The Mean

Introduction: Dialysis patients are often prescribed a large number of medications to improve metabolic control and manage coexisting comorbidities. However, some studies suggest that a large number of medications could also detrimentally affect patients’ health-related quality of life (HRQoL). Therefore, this study aims to provide insight in the association between the number of types of medications and HRQoL in dialysis patients. Methods: A multicentre cohort study was conducted among dialysis patients from Dutch dialysis centres 3 months after initiation of dialysis as part of the ongoing prospective DOMESTICO study. The number of types of medications, defined as the number of concomitantly prescribed types of drugs, was obtained from electronic patient records. Primary outcome was HRQoL measured with the Physical Component Summary (PCS) score and Mental Component Summary (MCS) score (range 0–100) of the Short Form 12. Secondary outcomes were number of symptoms (range 0–30) measured with the Dialysis Symptoms Index and self-rated health (range 0–100) measured with the EuroQol-5D-5L. Data were analysed using linear regression and adjusted for possible confounders, including comorbidity. Analyses for MCS and number of symptoms were performed after categorizing patients in tertiles according to their number of medications because assumptions of linearity were violated for these outcomes. Results: A total of 162 patients were included. Mean age of patients was 58 ± 17 years, 35% were female, and 80% underwent haemodialysis. The mean number of medications was 12.2 ± 4.5. Mean PCS and MCS were 36.6 ± 10.2 and 46.8 ± 10.0, respectively. The mean number of symptoms was 12.3 ± 6.9 and the mean self-rated health 60.1 ± 20.6. In adjusted analyses, PCS was 0.6 point lower for each additional medication (95% confidence interval [95% CI]: −0.9 to –0.2; p = 0.002). MCS was 4.9 point lower (95% CI: −8.8 to –1.0; p = 0.01) and 1.0 point lower (95% CI: −5.1–3.1; p = 0.63) for the highest and middle tertiles of medications, respectively, than for the lowest tertile. Patients in the highest tertile of medications reported 4.1 more symptoms than in the lowest tertile (95% CI: 1.5–6.6; p = 0.002), but no significant difference in the number of symptoms was observed between the middle and lowest tertiles. Self-rated health was 1.5 point lower for each medication (95% CI: −2.2 to –0.7; p < 0.001). Discussion/Conclusion: After adjustment for comorbidity and other confounders, a higher number of medications were associated with a lower PCS, MCS, and self-rated health in dialysis patients and with more symptoms.

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Quality-of-life evaluation using Short Form 36: Comparison in hemodialysis and peritoneal dialysis patients

American Journal of Kidney Diseases ◽

10.1016/s0272-6386(00)70339-8 ◽

2000 ◽

Vol 35 (2) ◽

pp. 293-300 ◽

Cited By ~ 153

Author(s):

Jose A. Diaz-Buxo ◽

Edmund G. Lowrie ◽

Nancy L. Lew ◽

Hongyuan Zhang ◽

J.Michael Lazarus

Keyword(s):

Quality Of Life ◽

Peritoneal Dialysis ◽

Short Form ◽

Dialysis Patients ◽

Short Form 36 ◽

Life Evaluation

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MO822POLYPHARMACY NEGATIVELY AFFECTS HEALTH-RELATED QUALITY OF LIFE IN DIALYSIS PATIENTS

Nephrology Dialysis Transplantation ◽

10.1093/ndt/gfab098.0014 ◽

2021 ◽

Vol 36 (Supplement_1) ◽

Author(s):

Julia Colombijn ◽

Anna Bonenkamp ◽

Anita Van Eck van der Sluijs ◽

Alferso C Abrahams ◽

Joost Bijlsma ◽

...

Keyword(s):

Quality Of Life ◽

Health Related Quality ◽

Dialysis Patients ◽

Self Rated Health ◽

Therapeutic Benefits ◽

Significant Difference ◽

Related Quality ◽

Health Related ◽

The Mean

Abstract Background and Aims Dialysis patients are often prescribed a large number of medications to improve metabolic control and manage co-existing comorbidities. However, several studies suggest that a large number of medications can also detrimentally affect their health-related quality of life (HRQoL). Therefore, this study aims to provide insight in the association between the number of medications and various aspects of HRQoL in dialysis patients. Method A multicentre study was conducted among dialysis patients from Dutch dialysis centres three months after initiation of dialysis as part of the ongoing prospective DOMESTICO study. The number of medications, defined as the number of concomitantly prescribed types of drugs, was obtained from electronic patient records. Primary outcome was HRQoL measured with the Physical Component Summary (PCS) score and Mental Component Summary (MCS) score (range 0-100) of the Short Form 12. Secondary outcomes were number of symptoms (range 0-30) measured with the Dialysis Symptoms Index and self-rated health (range 0-100) measured with the visual analogue scale of the EuroQol-5D-5L. Data were analysed using linear regression and adjusted for possible confounders, including age, sex, dialysis modality, and comorbidity. Analyses for MCS and number of symptoms were performed after categorising patients in tertiles according to their number of medications because assumptions of linearity were violated for these outcomes. Results A total of 162 patients were included. Mean age of patients was 58 ± 17 years, 35% were female, and 80% underwent haemodialysis. The mean number of medications was 12.2 ± 4.5. Mean PCS and MCS were 36.6 ± 10.2 and 46.8 ± 10.0, respectively. The mean number of symptoms was 12.3 ± 6.9 and mean self-rated health 60.1 ± 20.6. In adjusted analyses, PCS was 0.6 point lower for each additional medication (95%CI -0.9 – -0.2; p=0.002). MCS was 4.9 point lower (95%CI -8.8 – -1.0; p=0.01) and 1.0 point lower (95%CI -5.1 – 3.1; p=0.63) for the highest and middle tertiles of medications, respectively, compared to the lowest tertile. Patients in the highest tertile of medications reported 4.1 more symptoms compared to the lowest tertile (95%CI 1.5 – 6.6; p=0.002) but no significant difference in the number of symptoms was observed between the middle and lowest tertile. Self-rated health was 1.5 point lower for each medication (95%CI -2.2 – -0.7; p<0.001). Conclusion After adjustment for comorbidity and other confounders, a higher number of medications was associated with a lower PCS, MCS, and self-rated health in dialysis patients and with more symptoms. This suggests that it may be relevant to weigh expected therapeutic benefits of medication against their possible harmful effects on HRQoL. An unfavourable balance between expected benefits and impact on HRQoL might be ground to deviate from clinical guidelines, especially for patients with a limited life-expectancy and for whom a kidney transplant is unattainable.

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A Prospective, Randomized Multicenter Study Comparing APD and CAPD Treatment

Peritoneal Dialysis International ◽

10.1177/089686089901900606 ◽

1999 ◽

Vol 19 (6) ◽

pp. 526-533 ◽

Cited By ~ 86

Author(s):

Susanne Bro ◽

Jakob B. Bjorner ◽

Pernille Tofte–Jensen ◽

Susanne Klem ◽

Birte Almtoft ◽

...

Keyword(s):

Quality Of Life ◽

Peritoneal Dialysis ◽

Multicenter Study ◽

Sleep Problems ◽

Short Form ◽

Complication Rates ◽

Significant Difference ◽

Therapy Costs ◽

Improve Patient

Objective The goals for maintenance dialysis treatment are to improve patient survival, reduce patient morbidity, and improve patient quality of life. This is the first randomized prospective study comparing automated peritoneal dialysis (APD) and continuous ambulatory peritoneal dialysis (CAPD) treatment with respect to quality of life and clinical outcomes in relation to therapy costs. Design A prospective, randomized multicenter study. Setting Three Danish CAPD units. Patients Thirty-four adequately dialyzed patients with high or high-average peritoneal transport characteristics were included in the study. Twenty-five patients completed the study. Interventions After randomization, 17 patients were allocated to APD treatment and 17 patients to CAPD treatment for a period of 6 months. Medical and biochemical parameters were evaluated at monthly controls in the CAPD units. Quality-of-life parameters were assessed at baseline and after 6 months by the self-administered short-form SF-36 generic health survey questionnaire supplemented with disease- and treatment-specific questions. Therapy costs were compared by evaluating dialysis-related expenses. Main Outcome Measures Quality-of-life parameters, dialysis-related complications, dialysis-related expenses. Results The quality-of-life studies showed that significantly more time for work, family, and social activities was available to patients on APD compared to those on CAPD ( p < 0.001). Although the difference was not significant, there was a tendency for less physical and emotional discomfort caused by dialysis fluid in the APD group. Sleep problems, on the other hand, tended to be more marked in the APD group. Any positive effect of APD compared to CAPD on dialysis-related hospital days or complication rates could not be confirmed. With larger patient samples, it is possible, however, that a significant difference might have been achieved. The running costs for APD treatment were US $75 per day and for CAPD treatment US $61 per day. Conclusion If APD treatment can help to keep selected patients vocationally or socially active, paying the extra cost seems reasonable.

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Social support network and quality of life in multiple sclerosis patients

Arquivos de Neuro-Psiquiatria ◽

10.1590/0004-282x20170036 ◽

2017 ◽

Vol 75 (5) ◽

pp. 267-271 ◽

Cited By ~ 10

Author(s):

David Castro Costa ◽

Maria José Sá ◽

José Manuel Calheiros

Keyword(s):

Quality Of Life ◽

Multiple Sclerosis ◽

Social Support ◽

Short Form ◽

Support Network ◽

Social Support Network ◽

The Mean ◽

Multiple Sclerosis Patients ◽

The Relationship

ABSTRACT Objective To analyse the relationship between the social support network (SSN) and health related quality of life (HRQOL) in multiple sclerosis (MS) patients. Methods The sample comprised 150 consecutive MS patients attending our MS clinic. To assess the socio-demographic data, a specifically designed questionnaire was applied. The HRQOL dimensions were measured with the Short-Form Health Survey Questionnaire-SF36 and the SSN with the Medical Outcomes Study Social Support Survey. Spearman’s correlation was used to compare the magnitude of the relationship between the SSN and HRQOL. Results The mean patient age was 41.7 years (± 10.4; range: 18–70 yr); the mean Expanded Disability Status Score was 2.5 (±2.4; range: 0–9). There was a statistically significant correlation between the structure of the SSN and the HRQOL. Conclusion The composition of the SSN, social group membership and participation in voluntary work have an important role in the HRQOL of patients with MS.

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AB0715 THE PREVALENCE OF FIBROMIYALGIA IN PATIENTS WITH FAMILIAL MEDITERRANEAN FEVER AND THE RELATIONSHIP BETWEEN FATIGUE AND QUALITY OF LIFE

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2021-eular.1288 ◽

2021 ◽

Vol 80 (Suppl 1) ◽

pp. 1389.1-1389

Author(s):

S. Ugurlu ◽

T. Civi Karaaslan ◽

Z. Toker Dincer ◽

E. Tarakci

Keyword(s):

Quality Of Life ◽

Familial Mediterranean Fever ◽

Short Form ◽

Pearson Correlation ◽

Fibromyalgia Impact Questionnaire ◽

Sf 36 ◽

Mediterranean Fever ◽

The Mean ◽

The Relationship

Background:Familial Mediterranean Fever (FMF) can cause various muscle diseases. Because it is a chronic auto inflammatory disease, painful trigger points may be encountered in the examination due to a decrease in the pain threshold (1-3).Objectives:The aim of this study was to determine the prevalence of Fibromiyalgia in patients with FMF, at the same time to identify the relationship between fatigue and quality of life.Methods:Sixtyseven patients (38 female, 29 male) with FMF were enrolled in the study. They were diagnosed with FMF based on the Livneh diagnostic criteria (4). Fibromyalgia involvement of the patients was evaluated according to the Fibromyalgia Impact Questionnaire (FIQ). Patients with diagnose with other chronic disease were excluded. Fatigue Severity Scale (FSS) was used to evaluate fatigue. Quality of life was evaluated with Short Form-36 (SF-36).Results:Respectively, the mean age, disease duration and body mass index were 34.46±12.69 years, 12.66±7.86 years and 24.96±5.42 kg/m2. In addition, 65% of the patients had no rheumatic disease in their family history. The mean of scores of FIQ was 38.66±25.14, the mean of FSS was 38.07±17.56, the mean of SF-36-PCS was 45.55±10.54 and SF36-MCS was 30.93±17.39. Patients were categorized as mild (n=28), moderate (n=24) and severe (n=15) affected according to their FİQ score. The relationships of scores of FIQ, FSS and SF-36 were demonstrated Table 1.Conclusion:Fibromyalgia symptoms can be seen in FMF. According to our results, it has been shown that patients with moderate and severe symptoms have increased fatigue levels and decreased quality of life. In the light of these results, we can say that also the fibromyalgia symptom of patients with FMF should be considered in the treatment.References:[1]Sari, Ismail; Birlik, Merih; Kasifoglu, Timucin. Familial Mediterranean fever: an updated review. European journal of rheumatology, 2014, 1.1: 21.[2]Alayli G, Durmus D, Ozkaya O, Sen HE, Genc G, Kuru O. Frequency of juvenile fibromyalgia syndrome in children with familial Mediterranean fever: effects on depression and quality of life. Clin Exp Rheumatol 2011; 29: S127-32.[3]Langevitz P, Buskila D, Finkelstein R, Zaks N, Neuman L, Sukenik S, et al. Fibromyalgia in familial Mediterranean fever. J Rheumatol 1994; 21: 1335-7.[4]Bashardoust, Bahman. Familial Mediterranean fever; diagnosis, treatment, and complications. Journal of nephropharmacology, 2015, 4.1: 5.Table 1.The correlations of FIQ, FSS and SF-36 scores.FSSSF-36 PCSSF-36 MCSFIQ-mildmean±sd23.78±14.8853.34±7.0140.98±13.73r0.595**-0.014-0.551**p0.0010.9440.002FIQ-moderatemean±sd45.75±10.8341.09±8.8938.13±9.19r0.053-0.379-0.145p0.8060.0680.498FIQ-severemean±sd52.46±10.1138.13±9.1920.32±15.68r0.622*-0.548*-0.268p0.0130.0350.333-Pearson CorrelationDisclosure of Interests:None declared

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Nutritional status as a predictor of comprehensive activities of daily living function and quality of life in patients with stroke

Neurorehabilitation ◽

10.3233/nre-201540 ◽

2021 ◽

pp. 1-7

Author(s):

Ya-Chen Lee ◽

En-Chi Chiu

Keyword(s):

Quality Of Life ◽

Nutritional Status ◽

Activities Of Daily Living ◽

Daily Living ◽

Nutritional Assessment ◽

Short Form ◽

Mini Nutritional Assessment ◽

Cross Sectional ◽

Cross Sectional Design

BACKGROUND: Nutritional status could affect functional capacity and reduce quality of life in patients with stroke. Although the associations between nutritional status, basic activities of daily living (BADL)/Instrumental ADL, and quality of life (QOL) in older people have been identified, the relationships have not yet been examined in patients with stroke, using the full Mini Nutritional Assessment (MNA) or MNA-short form (MNA-SF). OBJECTIVE: This study aimed to examine the relationship between nutritional status (using full MNA and MNA-SF), comprehensive ADL function, and QOL in patients with stroke. METHODS: Eighty-two patients with ischemic stroke participated in this cross-sectional design study. Each participant was assessed with the full MNA, MNA-SF, comprehensive ADL function (including Barthel Index and Frenchay Activities Index), and WHO Quality of Life-BREF (WHOQOL-BREF) once. RESULTS: The MNA-SF was only significantly correlated with the comprehensive ADL function (rho = 0.27, p = 0.013), whereas, the full MNA was found to be significantly correlated with the comprehensive ADL function and WHOQOL (rho = 0.24, p = 0.029 and rho = 0.30, p = 0.005). The MNA-SF was a significant predictor of comprehensive ADL function, accounting for 44% of the variance. The full MNA was the only significant predictor of the WHOQOL-BREF, explaining 17% of the variance. CONCLUSIONS: This study has revealed a relationship between nutritional status, comprehensive ADL function, and QOL among patients with stroke. Patients with stroke with better nutritional status had higher ADL function as well as better QOL. The MNA-SF was useful in predicting comprehensive ADL, whereas, the full MNA could be used to predict QOL. Knowledge and evidence of the association and predictive power of the MNA-SF and full MNA could guide clinicians to choose tools for assessing the nutritional status of patients with stroke more effectively.

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Assessment of Quality of Life among Beta-Thalassemia Major Patients Attending the Hematology Outpatient Clinics at Cairo University Hospital

Open Access Macedonian Journal of Medical Sciences ◽

10.3889/oamjms.2021.5692 ◽

2021 ◽

Vol 9 (E) ◽

pp. 156-160

Author(s):

Mona Hamdy ◽

Iman Hassan Draz ◽

Inas Talaat El Sayed ◽

Azza Ali Fahmy Ayyad ◽

Marwa Rashad Salemd

Keyword(s):

Quality Of Life ◽

Blood Transfusion ◽

Short Form ◽

Age At Onset ◽

Thalassemia Major ◽

University Hospital ◽

Sf 36 ◽

Significant Difference ◽

The Mean

AIM: This paper aimed at assessing the quality of life (QoL) among beta (β)-thalassemia major patients using the short-form-36questionnaire (SF-36) and determining the factors associated with it. METHODS: A cross-sectional study was conducted among β-thalassemia major patients who were attending the hematology outpatient clinic at Cairo University Hospital using the consecutive sampling technique. Data were collected between October 2016 and March 2017. The QoL was assessed for patients aged ≥17 years. During the study period, a total number of 112 patients were included for participation. RESULTS: The mean age of the studied group was 18.32 ± 1.33 years. Most of the included patients (93.63%) had 1 monthly blood transfusion. The mean total score of SF-36 was 44.90 ± 7.54. Among the QoL domains of the studied patients, the “general health perception” domain was the most affected one with a mean score of (add the value of the score here), while the “vitality” domain was the least affected one. No statistically significant difference was reported between males and females regarding different QoL domains except for the “vitality” domain which mean score was significantly higher in males compared to females (p = 0.05). The age at onset of the disease and at first blood transfusion was the most documented factors to be positively correlated with the QoL among the studied patients. CONCLUSION: This study revealed that the QoL in thalassemia major patients is compromised. QoL assessment should be performed for all thalassemia patients to determine and implement the necessary interventions that focus on the affected domains.

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