scholarly journals AB0715 THE PREVALENCE OF FIBROMIYALGIA IN PATIENTS WITH FAMILIAL MEDITERRANEAN FEVER AND THE RELATIONSHIP BETWEEN FATIGUE AND QUALITY OF LIFE

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1389.1-1389
Author(s):  
S. Ugurlu ◽  
T. Civi Karaaslan ◽  
Z. Toker Dincer ◽  
E. Tarakci
Keyword(s):  
Quality Of Life ◽  
Familial Mediterranean Fever ◽  
Short Form ◽  
Pearson Correlation ◽  
Fibromyalgia Impact Questionnaire ◽  
Sf 36 ◽  
Mediterranean Fever ◽  
The Mean ◽  
The Relationship

Background:Familial Mediterranean Fever (FMF) can cause various muscle diseases. Because it is a chronic auto inflammatory disease, painful trigger points may be encountered in the examination due to a decrease in the pain threshold (1-3).Objectives:The aim of this study was to determine the prevalence of Fibromiyalgia in patients with FMF, at the same time to identify the relationship between fatigue and quality of life.Methods:Sixtyseven patients (38 female, 29 male) with FMF were enrolled in the study. They were diagnosed with FMF based on the Livneh diagnostic criteria (4). Fibromyalgia involvement of the patients was evaluated according to the Fibromyalgia Impact Questionnaire (FIQ). Patients with diagnose with other chronic disease were excluded. Fatigue Severity Scale (FSS) was used to evaluate fatigue. Quality of life was evaluated with Short Form-36 (SF-36).Results:Respectively, the mean age, disease duration and body mass index were 34.46±12.69 years, 12.66±7.86 years and 24.96±5.42 kg/m2. In addition, 65% of the patients had no rheumatic disease in their family history. The mean of scores of FIQ was 38.66±25.14, the mean of FSS was 38.07±17.56, the mean of SF-36-PCS was 45.55±10.54 and SF36-MCS was 30.93±17.39. Patients were categorized as mild (n=28), moderate (n=24) and severe (n=15) affected according to their FİQ score. The relationships of scores of FIQ, FSS and SF-36 were demonstrated Table 1.Conclusion:Fibromyalgia symptoms can be seen in FMF. According to our results, it has been shown that patients with moderate and severe symptoms have increased fatigue levels and decreased quality of life. In the light of these results, we can say that also the fibromyalgia symptom of patients with FMF should be considered in the treatment.References:[1]Sari, Ismail; Birlik, Merih; Kasifoglu, Timucin. Familial Mediterranean fever: an updated review. European journal of rheumatology, 2014, 1.1: 21.[2]Alayli G, Durmus D, Ozkaya O, Sen HE, Genc G, Kuru O. Frequency of juvenile fibromyalgia syndrome in children with familial Mediterranean fever: effects on depression and quality of life. Clin Exp Rheumatol 2011; 29: S127-32.[3]Langevitz P, Buskila D, Finkelstein R, Zaks N, Neuman L, Sukenik S, et al. Fibromyalgia in familial Mediterranean fever. J Rheumatol 1994; 21: 1335-7.[4]Bashardoust, Bahman. Familial Mediterranean fever; diagnosis, treatment, and complications. Journal of nephropharmacology, 2015, 4.1: 5.Table 1.The correlations of FIQ, FSS and SF-36 scores.FSSSF-36 PCSSF-36 MCSFIQ-mildmean±sd23.78±14.8853.34±7.0140.98±13.73r0.595**-0.014-0.551**p0.0010.9440.002FIQ-moderatemean±sd45.75±10.8341.09±8.8938.13±9.19r0.053-0.379-0.145p0.8060.0680.498FIQ-severemean±sd52.46±10.1138.13±9.1920.32±15.68r0.622*-0.548*-0.268p0.0130.0350.333-Pearson CorrelationDisclosure of Interests:None declared

The Relationship of Opiate Analgesia to Quality of Life in an Adult Sickle Cell Population.

Blood ◽  
2007 ◽  
Vol 110 (11) ◽  
pp. 2261-2261
Author(s):  
Soheir S. Adam ◽  
Jude C. Jonassaint ◽  
Charles R. Jonassaint ◽  
Laura M. De Castro ◽  
Marilyn J. Telen
Keyword(s):  
Quality Of Life ◽  
Pain Management ◽  
Sickle Cell ◽  
Short Form ◽  
Limiting Factor ◽  
Opioid Analgesia ◽  
Sf 36 ◽  
The Mean ◽  
The Relationship

Abstract Pain is a limiting factor in the daily life activities of sickle cell disease (SCD) patients. Opioid analgesics are widely used for management of SCD-related chronic pain in the community. To date there have been no studies on the use of opioids and their impact on quality of life (QoL) measures in this population. Patients on long-term opioid pain management may also be on hydroxyurea (HU), which is often used to decrease the frequency of painful episodes and other SCD sequelae. HU is also known to affect some QoL measures. The aim of this study was to determine the effect of opioid analgesia on QoL measures in an adult SCD population. This study included 185 patients, 92 females and 93 males, from the outpatient clinic at Duke University Medical Center. 117 patients either had homozygous SCD or were doubly heterozygous for Sβ0 thalassemia; 68 patients were of different genotypes. Data were collected by patient interviews as well as review of medical records after informed consent. The Medical Outcome Study 36-item Short Form (SF-36) was used to determine QoL measures, and the results were scored in standard fashion. Differences in variables of interest between narcotic users and narcotic non-users were analyzed using t-tests. ANOVAs were used to identify combined effects of narcotics, HU and their interaction with SF-36 scores. Gender, age and genotypes were included as covariates. Patient data were classified in 4 groups based on report of regular use of opioids (at least 30 days within the preceding year) and HU (any use during the preceding year) as follows: no HU or narcotics (none); narcotics only; HU only; and narcotics and HU. SF-36 scores for all physical and mental domains were significantly lower in individuals on opiates vs those not on opiates, in all age groups (p<.01). Controlling for HU use did not affect the association of opioid use with lower SF-36 scores. We also examined the relationship between hemoglobin, white blood cell count (WBC) and oxygen saturation in the different medication groups. WBC counts were significantly higher in individuals using opioids when compared to those who were not on opioids. Patients on HU and narcotics also had higher WBC than those on HU alone. The frequency of hospitalization was significantly higher in the opioid only group, as compared to the other 3 groups (p=.02). While HU was found to have a positive impact on certain aspects of QoL, it added very little to QoL in individuals who were on both HU and narcotics. Since the efficacy of HU was strongly related to the decrease in WBC, we compared the mean values of WBC in all medication groups. HU significantly lowered the WBC count, but the concurrent use of opioids partially obliterated this effect. This cannot be explained by poor compliance, as the mean WBC were lower in the HU and opiates than in the opiate only group. Our results suggest that further studies are needed to determine whether other factors play a role in QoL outcomes. Other pain management strategies should also be investigated due to the apparent association of opioid analgesia with lower QoL in this patient population. Figure Figure

scholarly journals The Relationship Between Physical Activity Level with Quality of Life and General Health among COVID-19 Recovered Individuals

2021 ◽  
Author(s):  
Mahnaz Azmodeh ◽  
Rastegar Hoseini ◽  
Ehsan Amiri
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Physical Activity Level ◽  
General Health ◽  
Short Form ◽  
Pearson Correlation ◽  
Activity Level ◽  
Men And Women ◽  
The Relationship

Abstract Background: New coronavirus (COVID-19) has a major impact on the individual's physical activity level (PAL); The COVID-19 quarantine outbreak caused a decrease in the PAL. Accordingly, it might also affect the general health and quality of life (QoL). This study aimed to evaluate the relationship between PAL with QoL and general health (GH) among COVID-19 recovered individuals (CRI).Methods: In this descriptive-analytical study, using the multi-stage (Cluster) sampling techniques, 890 CRI (male (n = 438) and female (n = 452)) were volunteered from different COVID-19 testing centers in Kermanshah province. After filling out the consent form, the PAL, GH, and QoL questionnaires were completed and anthropometric parameters were measured. The PAL was assessed using the international physical activity questionnaire (IPAQ-SF), GH was assessed using the GHQ questionnaire and the QoL was measured by the QoL questionnaire (short-form-SF-12). The independent t-test was used to compare the mean of variables between men and women and the Pearson correlation coefficient test was used to evaluate the relationship between variables using SPSS software version 24 at a significant level of (P≤0.05). Results: The findings of the present study showed that men and women with COVID-19 had inadequate PAL (876.11±40.23;739.08±27.02), insufficient GH (50.13±3.1; 54.15±4.28), and poor QoL (22.02±2.28; 19.23±1.87), respectively. The results also showed that men had significantly higher PAL (P=0.035), GH (P=0.047), and QoL (P=0.023) compared to women. Also, the results show that increasing the PAL improves GH and QoL. Conclusions: Considering the prevalence of COVID-19 and its negative impact on GH and QoL, maintaining adequate PAL can be considered as one of the effective strategies for improving physical and GH, and immune systems, by observing the hygiene protocol.

Hemodialysis and peritoneal dialysis—health-related quality of life: systematic review plus meta-analysis

2021 ◽  
pp. bmjspcare-2021-003182
Author(s):  
Samira Raoofi ◽  
Fatemeh Pashazadeh Kan ◽  
Sima Rafiei ◽  
Zahra Hoseinipalangi ◽  
Sepide Rezaei ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Short Form ◽  
Meta Analysis ◽  
Health Condition ◽  
Factors Affecting ◽  
Sf 36 ◽  
Wide Range ◽  
Health Related ◽  
The Mean

BackgroundPatients with end-stage renal disease undergoing haemodialysis experience a variety of stressors leading to decreased level of quality of life (QoL). Thus, in this study, we aimed to review the current literature and identify factors affecting the health-related QoL (HRQoL) in these patients.MethodsA total of 147 studies were extracted from databases of Web of Science, PubMed, Scopus, Google Scholar, and Embase published between January 2000 and December 2020. Data were analysed using R software and results were reported with reference to Preferred Reporting Items for Systematic Reviews and Meta-Analyses standards.ResultsA total of 623 728 patients undergoing dialysis participated in 147 studies in which QoL was assessed by means of two valid questionnaires, including Short-Form 36 (SF-36) and Kidney Disease Quality of Life (KDQOL)-short form V.1.3. Total HRQoL score for patients undergoing dialysis measured by KDQOL was 64.25 (95% CI 55.67 to 72.82). Based on SF-36, the mean score of mental health items was higher than the mean score of physical health condition. Furthermore, meta-regression based on the geographical place of residence revealed that the highest QoL in patients was observed in Japan, 66.96 (95% CI 63.65 to 70.28) and Brazil, 58.03 (95% CI 53.45 to 62.6).ConclusionStudies conducted on HRQoL among patients undergoing dialysis recommend useful strategies to clinicians, letting them assess patients’ QoL in terms of a wide range of physical, mental and environmental aspects.

scholarly journals Social support network and quality of life in multiple sclerosis patients

2017 ◽  
Vol 75 (5) ◽  
pp. 267-271 ◽  
Author(s):  
David Castro Costa ◽  
Maria José Sá ◽  
José Manuel Calheiros
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Social Support ◽  
Short Form ◽  
Support Network ◽  
Social Support Network ◽  
The Mean ◽  
Multiple Sclerosis Patients ◽  
The Relationship

ABSTRACT Objective To analyse the relationship between the social support network (SSN) and health related quality of life (HRQOL) in multiple sclerosis (MS) patients. Methods The sample comprised 150 consecutive MS patients attending our MS clinic. To assess the socio-demographic data, a specifically designed questionnaire was applied. The HRQOL dimensions were measured with the Short-Form Health Survey Questionnaire-SF36 and the SSN with the Medical Outcomes Study Social Support Survey. Spearman’s correlation was used to compare the magnitude of the relationship between the SSN and HRQOL. Results The mean patient age was 41.7 years (± 10.4; range: 18–70 yr); the mean Expanded Disability Status Score was 2.5 (±2.4; range: 0–9). There was a statistically significant correlation between the structure of the SSN and the HRQOL. Conclusion The composition of the SSN, social group membership and participation in voluntary work have an important role in the HRQOL of patients with MS.

scholarly journals AB0064 EVALUATION OF QUALITY OF LIFE IN RHEUMATOID ARTHRITIS USING SF-36 AND HAQ SCALES

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1063.1-1063
Author(s):  
M. Brahem ◽  
M. Hassayoun ◽  
H. Hachfi ◽  
R. Sarraj ◽  
M. Ardhaoui ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Rheumatoid Arthritis ◽  
Disease Activity ◽  
Short Form ◽  
Bodily Pain ◽  
Global Score ◽  
Sf 36 ◽  
The Mean ◽  
The Impact

Background:The assessment of health-related quality-of-life (HRQoL) in rheumatoid arthritis (RA) is becoming a common tool in clinical practice. The medical outcomes survey short form 36 (SF- 36) is one of the most widely used tools for measuring HRQoL in RA as well as the HAQ scale.Objectives:The aim of our study is to evaluate the impact of the RA in the quality of life (QoL) of our patients using the SF-36 and the HAQ questionnaires.Methods:This is a cross-sectional study during a period of the year 2020, including 70 patients followed in the department of Rheumatology in Mahdia, Tunisia. All patients were diagnosed with RA based in ACR 1987/EULAR 2010. We evaluated for each patient, the mean global scale and the eight domains of SF-36 (physical functioning (PF), role physical (RP), bodily pain (BP), general health (GH), vitality (VT), a social functioning (SF), role emotional (RE) and mental health (MH)), scored from 0 (worst) to 100 (best).Results:Our study included 70 patients (59 females/11males) with an age ranged from 21 to 76 years. The mean age was 54 ± 12 years. The mean duration of the disease was 11 ± 10 years [1-40]. The mean number of tender joints was 9.7 ±9.4 and swollen joints were 4.2 ±6.1. The mean disease activity score (DAS28) was 4.6 ±1.9 [1.2-8.4]. The mean HAQ score was 1.5±1.3, 47.1% of patients had specific joint deformations, 82.9% had radiologic involvement and 31.4% had osteoporosis. The biologic analysis showed that the mean ESR was 46.7 ± 30.5 and the CRP was 15.8 ±23.3. Rheumatoid factors were positive in 42.9% of cases, the ACPA were positive in 50% of cases. 84.3% of RA patients were treated by methotrexate, 4.3% were treated by salazopyrin and 11.4% were treated by biologic treatments.The SF-36 global score was 50.4 ± 26.3 [15.3-92.8]. 46 patients (65.7% of cases) had impaired QoL (SF-36<66.7). The means of different domains (PF, RP, BP, GH, VT, SF, RE, MH) were respectively 51; 41.4; 51.4; 50; 51.2; 57.7; 41.9; 59.2. The most severely impacted domains were the RP and RE.Our study showed a significant correlation between the SF-36 global score and the number of tender joints (p=0.002), the DAS28 (p=0.017) and the HAQ(p=0.000).Conclusion:Our study showed that 65.7% of RA patients presented impaired QoL (SF-36<66.7), which is associated with high disease activity. So it’s important to jugulate the disease, in order to ameliorate the quality of life of our patients.References:[1]Matcham, F., Scott, IC, Rayner, L., Hotopf, M., Kingsley, GH, Norton, S.,… Steer, S. (2014). L’impact de la polyarthrite rhumatoïde sur la qualité de vie évalué à l’aide du SF-36: une revue systématique et une méta-analyse. Séminaires sur l’arthrite et les rhumatismes, 44 (2), 123-130. doi: 10.1016 / j.semarthrit.2014.05.001.Disclosure of Interests:None declared

scholarly journals AB1024 EVALUATION OF CLINICAL FEATURES IN PATIENTS DIAGNOSED WITH JUVENILE AND ADULT-ONSET FAMILIAL MEDITERRANEAN FEVER

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1804.2-1805
Author(s):  
D. Erdem Gürsoy ◽  
H. H. Gezer ◽  
S. Acer Kasman ◽  
N. Öz ◽  
A. Ozer ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Familial Mediterranean Fever ◽  
Disease Activity ◽  
Clinical Features ◽  
Categorical Variables ◽  
Adult Onset ◽  
Juvenile Onset ◽  
Sf 36 ◽  
Mediterranean Fever

Background:Familial Mediterranean Fever (FMF), which is more common in groups in the Mediterranean basin, is a monogenic auto inflammatory disease characterized by recurrent attacks of febrile peritonitis, pleuritis and arthritis.Objectives:The aim of this study is to investigate the clinical features of patients diagnosed with juvenile and adult-onset Familial Mediterranean Fever (FMF).Methods:Patients with FMF were included in the study consecutively without sample selection. Data about age, sex, disease duration (month), symptom duration, age at diagnosis, diagnosis delay time, comorbid diseases, and medications were noted. Patients with onset of symptoms ≤ 20 years old were classified as juvenile-onset, those > 20 years old were classified as adult-onset FMF. The frequency and characteristics of attacks and the presence of amyloidosis will be recorded.Disease activity was assessed with the PRAS disease activity score. The Health Assessment Questionnaire (HAQ) and SF-36 were used to evaluate physical disability and quality of life, respectively.The descriptive analysis was done for all parameters. Differences between categorical variables were assessed by Chi-square test and Fisher’s exact test. The Mann Whitney-U test was used to compare two sample means. P<0.05 accepted as significant. SPSS 20.0 (Statistical package for social sciences for Windows 20.0) program was used for the statistical analysis.Results:The mean age of 86 patients (63 female, 23 male) with FMF was 38.38 (SD: 12.13) years. The patients with the juvenile-onset FMF were 26.7% of the patients.There were no differences between juvenile and adult-onset FMF groups in terms of gender, frequency of attacks, duration of attacks, acute phase values between attacks, colchicine dose, presence of colchicine resistance, and presence of amyloidosis (p>0.05). The latency to diagnosis was significantly higher in patients with adult-onset FMF (p<0.005).The PRAS disease activity scores were significantly higher in the juvenile-onset FMF group (p=0.001). There were no significant differences between the two groups in terms of SF-36 and HAQ scores (p> 0.05).Conclusion:While there were no differences between juvenile and adult-onset FMF patients in terms of quality of life and functional disability, the PRAS disease activity scores were higher in patients with juvenile-onset FMF.References:[1]Shinawi M, Brik R, Kepten I, Berant M, Gersoni B. Familial Mediterranean fever: high gene frequency and heterogenous disease among Israeli-Moslem Arab population. J Rheumatol 2000;27:1492–5.Disclosure of Interests:None declared

scholarly journals Comparing the SF-36 and SF-12 in Psychometric Properties as Measuring Quality of Life among Adolescent in China: a Large Sample Cross-sectional Study

2020 ◽  
Author(s):  
Yanwei Lin ◽  
Yulan Yu ◽  
Jiayong Zeng ◽  
Xudong Zhao ◽  
Chonghua Wan
Keyword(s):  
Quality Of Life ◽  
Psychometric Properties ◽  
Item Difficulty ◽  
Short Form ◽  
Pearson Correlation ◽  
Cross Sectional Study ◽  
Load Factor ◽  
Cross Sectional ◽  
Sf 36

Abstract Objective: By comparing psychometric properties of the SF-36 and the SF-12, supplied evidence for the election of instruments of the quality of life (QOL) and decision-making processes to promote the Quality of Life of adolescent. Methods: Stratified cluster random sampling was adopted. The Short-Form 36 (SF-36) was used to assess QOL. Pearson Correlation Coefficient was used to show correlation. Cronbach’s Alpha and Construct Reliability (CR) were used to evaluate reliability of SF-36 and the Short-Form 12 (SF-12), Criterion Validity and Average Variance Extracted (AVE, Convergence Validity) for validity. Confirmatory factor analysis was used to calculate load factor for each item, then obtained CR and AVE. The Semejima grade response model (Logistic two-parameter module) in the item response theory was used to estimate the Item Discrimination, Item Difficulty and Item Average Information of each item. Results: 19,428 samples were included in the study. The mean age was 14.78 years (SD=1.77). High correlations between corresponding domains and components of both scales were found. Reliability of sf-36 each domain was better than that corresponding domain of sf-12. Domains of PF, RP, BP, and GH in SF-36 had good construct reliability (CR,>0.6). The Criterion Validities of SF-36 were little higher in some corresponding dimensions except PCS. Convergence validities of SF-12 were higher than SF-36 in PF, RP, BP and PCS. The items of BP, SF, RP and VT in SF-12 had acceptable discriminations of items and higher than in SF-36. The items Average Amounts of Information of BP, VT, SF, RE and MH in SF-36 and SF-12 were poor. Conclusion: Two components (PCS and MCS) measurements of SF-12 appeared to perform at least as well as the SF-36 in cross-sectional settings in adolescence. Some domains, for instance SF and BP, were suitable for adolescents or not need study further.

scholarly journals Care Burden and Related Factors on the Caregivers of Patients Receiving Service from Hemodialysis Unit

2021 ◽  
Author(s):  
Mucahit AKCIN ◽  
Mahcube CUBUKCU
Keyword(s):  
Quality Of Life ◽  
Short Form ◽  
Demographic Data ◽  
Hemodialysis Patients ◽  
Related Factors ◽  
Care Burden ◽  
Hemodialysis Unit ◽  
Sf 36 ◽  
The Mean

Introduction Caregivers of hemodialysis patients may experience stress, depression, fatigue, and decreased quality of life. This study aimed to examine the caregiver burden and related factors in patients’ caregivers under dialysis treatment. Method Our study was conducted between February and April 2019 in the Hemodialysis Unit of our Hospital Internal Diseases Clinic. Eighty-three people providing primary care to patients who had received hemodialysis service for at least three months were included in the study. The socio-demographic data of the caregivers were recorded. Care burden was evaluated by Zarit Burden Interview (ZBI) and dependency status with Katz Activities of Daily Living (ADL) instrument. Quality of life was evaluated with the 36-Item Short Form Survey (SF-36). Results The mean age of 183 caregivers included in the study was 46.35 ± 24.20 years; 67.5% of them were female. The mean ZBI score of the caregivers was 32.5 ± 14.4. Care burden was observed to be absent or very mild in 20.5% of the caregivers, mild-moderate in 57.8%, moderate-heavy in 19.3%, and heavy in 2.4%. The care burden was higher in those who felt insufficient to provide care or did not receive help from other family members for patient care (p<0.05). Besides, if the hemodialysis frequency was more than three times a week, the care burden was higher (p=0.003). Care burden was higher in functionally dependent patient (p=0.013). ZBI was negatively correlated with the SF-36 subscales, except for the physical function subscale (p<0.05). Conclusion The care burden was high in primary caregivers of hemodialysis patients. The care burden was higher in caregivers of patients with bedridden, high frequency of hemodialysis, and low quality of life. In addition to hemodialysis patients’ routine treatment, it may be appropriate to develop support groups and new care approaches for caregivers to reduce the care burden.

scholarly journals Comparing the reliability and validity of the SF-36 and SF-12 in measuring quality of life among adolescents in China: a large sample cross-sectional study

2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Yanwei Lin ◽  
Yulan Yu ◽  
Jiayong Zeng ◽  
Xudong Zhao ◽  
Chonghua Wan
Keyword(s):  
Quality Of Life ◽  
Item Difficulty ◽  
Short Form ◽  
Pearson Correlation ◽  
Geographical Location ◽  
Reliability And Validity ◽  
Cross Sectional ◽  
Sf 36 ◽  
Better Than

Abstract Objective We compare the reliability and validity of the Short Form 36 (version 1, SF-36) and the Short Form 12 (version 1, SF-12) in adolescence, the period of life when a child develops into an adult, i.e., the period from puberty to maturity terminating legally at the age of majority (10–19 years), thus supplying evidence for the selection of instruments measuring the quality of life (QOL) and decision-making processes of adolescents in China. Methods Stratified cluster random sampling was adopted according to geographical location, and the SF-36 was administered to assess QOL. The Pearson correlation coefficient was used to show correlation. Cronbach’s alpha and construct reliability (CR) were used to evaluate the reliability of SF-36 and SF-12, while criterion validity and average variance extracted (AVE, convergence validity) were used to evaluate validity. Confirmatory factor analysis was used to calculate the load factors for the items of the SF-36 and SF-12, then to obtain the CR and AVE. The Semejima grade response model (logistic two-parameter module) in item response theory was used to estimate item discrimination, item difficulty, and item average information for the items of the SF-36 and SF-12. Results 19,428 samples were included in the study. The mean age of respondents was 14.78 years (SD = 1.77). Reliability of each domain of the SF-36 was better than for the corresponding domain of the SF-12. The domains of PF, RP, BP, and GH in SF-36 had good construct reliability (CR > 0.6). The criterion validities of some domains of the SF-36 were a little higher in some corresponding dimensions of the SF-12, except for PCS. The convergence validities of the SF-12 were higher than the SF-36 in PF, RP, BP, and PCS. The items of BP, SF, RP, and VT in the SF-12 had acceptable discrimination of items that were higher than in the SF-36. The items’ average amounts of information on BP, VT, SF, RE, and MH in the SF-36 and SF-12 were poor. Conclusion Two component (PCS and MCS) measurements of the SF-12 appeared to perform at least as well as the SF-36 in cross-sectional settings in adolescence, but the reliability and validity of the 8 domains of the SF-36 were better than those of the SF-12. Some domains, for instance SF and BP, were not suitable for adolescents or need to be studied further.

scholarly journals Melatonin Improves Mood Status and Quality of Life and Decreases Cortisol Levels in Fibromyalgia

2018 ◽  
Vol 21 (1) ◽  
pp. 22-29 ◽  
Author(s):  
M. Yolanda Castaño ◽  
Maria Garrido ◽  
Ana Beatriz Rodríguez ◽  
M. Ángeles Gómez
Keyword(s):  
Quality Of Life ◽  
Short Form ◽  
Fibromyalgia Impact Questionnaire ◽  
Baseline Period ◽  
The State ◽  
Urinary Cortisol ◽  
Sf 36 ◽  
Cortisol Levels ◽  
Different Doses

Background: Mood disturbances are implicated in the pathogenesis of fibromyalgia. The aim of this study was to assess the effect of different doses of melatonin on quality of life, mood status, pain, anxiety, and urinary cortisol levels in patients with fibromyalgia. Methods: After a 10-day baseline period for the collection of data about participants’ initial status, participants took different doses of melatonin for 10 consecutive days each, with placebo given during the 10 days either before or between melatonin doses. Participants’ moods, quality of life, and pain levels were assessed using the Fibromyalgia Impact Questionnaire (FIQ), a Numerical Pain Scale (NPS), the State-Trait Anxiety Test (STAI), a Visual Analog Scale (VAS), and the Short Form-36 Health Survey (SF-36). Urinary cortisol levels were measured using enzyme-linked immunoassay. Results: Doses of 9, 12, and 15 mg of melatonin were associated with decreases in the total score of the FIQ, NPS scores, and urinary cortisol levels. The State-Anxiety subscale of the STAI improved after the 12 mg dose. The scores on the VAS improved after the 9 mg dose. The dimensions evaluated in the SF-36 questionnaire improved after the 9 mg dose. Conclusion: Melatonin improved mood, anxiety levels, and quality of life while decreasing cortisol levels in patients with fibromyalgia.

Sign in / Sign up

Export Citation Format

Share Document