scholarly journals Use of a commercial ELISA kit specific for glycoprotein E peptides to indirectly detect Caprine Herpesvirus 1 (CpHV-1) in the state of São Paulo, Brazil

2020 ◽  
Vol 87 ◽  
Author(s):  
Lilian Gregory ◽  
Natália Carrillo Gaeta ◽  
Astrid Bettini ◽  
Marco Ceol ◽  
Alexander Tavella

ABSTRACT: Caprine herpesvirus 1 (CpHV-1) infection is associated with clinical manifestations related to animal age, with high mortality in kids and infertility in adults. Given the scarcity of research about the epidemiological situation of this infection in Brazilian flocks, we aimed to conduct a cross-sectional descriptive study to detect antibodies against CpHV-1 in goats in the state of São Paulo, Brazil. Fifty-five male and female goats — kids and adult — were assessed in this study. Blood serum was analyzed by a commercial ELISA kit to detect antibodies against CpHV-1, which had not been used in Brazil before. No animals were reactive. Brazil lacks information about CpHV-1 infection in goat flocks. Continuing the study is crucial to understand the epidemiological situation of the disease and establish protocols for infection control.

2007 ◽  
Vol 125 (3) ◽  
pp. 180-185
Author(s):  
Ana Paula de Carvalho Panzeri Carlotti ◽  
Maria Lúcia Silveira Ferlin ◽  
Francisco Eulógio Martinez

CONTEXT AND OBJECTIVE: Neonatal resuscitation should be part of medical school curriculums. We aimed to evaluate medical school graduates' knowledge of neonatal resuscitation. DESIGN AND SETTING: Cross-sectional study on the performance of candidates sitting a medical residency exam at Hospital das Clínicas, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, in 2004. METHODS: There were two questions on neonatal resuscitation. One question in the theory test aimed at evaluating basic knowledge on the initial approach towards newly born infants. The question in the practical exam was designed to evaluate the candidate's ability to perform the initial steps of resuscitation and to establish bag-mask ventilation. RESULTS: Out of 642 candidates from 74 medical schools, 151 (23.5%) answered the theory question correctly. Significantly more physicians from public medical schools in the State of São Paulo answered correctly than did those from other schools in Brazil (52.5% versus 9.2%; p < 0.05). A total of 436 candidates did the practical exam. The grades among graduates from medical schools belonging to the State of São Paulo were significantly higher than among those from other schools (5.9 ± 2.6 versus 4.1 ± 2.1; p < 0.001). The grades for the practical question among candidates who had answered the theory question correctly were significantly higher than those obtained by candidates who had given wrong answers (p < 0.05). CONCLUSION: Medical school graduates' knowledge of neonate resuscitation in the delivery room is quite precarious. Emphasis on neonatal resuscitation training is urgently needed in medical schools.


2021 ◽  
Author(s):  
Isaac Rêgo Purificação ◽  
Allêh Kauãn Santos Nogueira ◽  
Matheus Araújo de Souza ◽  
Camila de Almeida Costa Alencar ◽  
Sancha Mohana Brito Goes Rios

Background: Cerebrovascular disease (CVD) is the world 2nd death cause and the main cause of disability. Nevertheless, there is a lack of information regarding the mortality profile for this etiology in the last decade. Objective and Methods: Using prospectively collected data available in TabNet (DataSUS) platform, a descriptive and cross-sectional study was conducted. The primary objective is to access the demographic information most associated with DCV mortality in individuals older than 50 years-old, in São Paulo (SP), from 2010 to 2019. Results: The highest mortality in the state of SP was in 2019 (16,945 deaths), according to the growing trend; in the 2010-2019 period, the annual mean by city of deaths (± standard deviation [SD]) was 14,885 (± 1,341). During these years, the number of deaths was higher in the municipality of São Paulo (57,013; 31%). The annual mean deaths (± SD) in the capital and in the interior cities were, respectively: 4,684 (± 269) and 31 (± 58). The age groups from 70 to 79 years and over 80 years were the most affected. Caucasian race represents 71% of deaths. Individuals with 1 to 3 years of school were more affected (38%). The ratio of male deaths to female deaths was 1.02. Conclusion: In the last decade, there was an increasing mortality by CVD among the elderly population, and the city of São Paulo leads the number of cases.


2014 ◽  
Vol 132 (1) ◽  
pp. 55-60 ◽  
Author(s):  
Mario Cesar Scheffer

CONTEXT AND OBJECTIVE: Given that Brazil has a universal public policy for supplying medications to treat HIV and AIDS, the aim here was to describe the forms of relationship between physicians and the pharmaceutical companies that produce antiretrovirals (ARVs). DESIGN AND SETTING: Cross-sectional epidemiological study conducted in the state of São Paulo. METHODS : Secondary database linkage was used, with structured interviews conducted by telephone among a sample group of 300 physicians representing 2,361 professionals who care for patients with HIV and AIDS. RESULTS : Around two thirds (64%) of the physicians prescribing ARVs for HIV and AIDS treatment in the state of São Paulo who were interviewed declared that they had some form of relationship with pharmaceutical companies, of which the most frequent were receipt of publications (54%), visits by sales promoters (51%) and receipt of small-value objects (47%). CONCLUSIONS: Two forms of relationship between the pharmaceutical industry and physicians who deal with HIV and AIDS can be highlighted: facilitation of professionals' access to continuing education; and antiretroviral drug brand name promotion.


2016 ◽  
Vol 49 (1) ◽  
pp. 25-30 ◽  
Author(s):  
Henrique Meiroz de Souza Almeida ◽  
Gabriel Yuri Storino ◽  
Daniele Araújo Pereira ◽  
Igor Renan Honorato Gatto ◽  
Luis Antonio Mathias ◽  
...  

2021 ◽  
Author(s):  
Paulo Roberto Hernandes Júnior ◽  
Juliana de Souza Rosa ◽  
Patrick de Abreu Cunha Lopes ◽  
Bárbara Tisse da Silva ◽  
Heloá Santos Faria da Silva ◽  
...  

Background: Cerebral hemorrhage represents 10% to 15% of all strokes, with the worst prognosis and the highest rate of morbimortality. Objectives: To analyze the panorama of conservative treatment procedures for cerebral hemorrhage in the State of São Paulo and correlate it with the current epidemiology. Methods: observational, descriptive and cross-sectional collection of conservative treatment data for cerebral hemorrhage, available at DATASUS website, from January 2008 up to December 2020 - evaluating the number of hospitalizations, public spending, complexity, mortality rate, deaths, permanence and character of care. Results: 15,327 hospitalizations were observed for such procedures in this period, representing a total expenditure of R$ 30,258,539.39. 2008 was the year with the highest number of hospitalizations (1,373), and 2020 was the year with the greatest expenditure (R$ 3,008,526.38). 552 of the were elective and 14,606 were urgent, with 4,102 occurring in the public sector and 4,510 in private one. All 15,327 considered to be of medium complexity. The mortality rate was 29.68, corresponding to 4,549 deaths, 2009 was the year with the highest mortality, 33.33 and 2008 the lowest, 24.33. Mortality rate was lower in elective procedures (15.40 versus 30.48 in urgent ones) and when carried out in public sector (27.16 versus 30.07 in private care). The hospital stay was 11.0 days, with a cost of R$ 1,974.20. Conclusion: The conservative treatment of cerebral hemorrhage represents a procedure of medium complexity with a long period of hospital stay. Higher mortality was observed in emergency care and the private sector.


2017 ◽  
Vol 43 (2) ◽  
pp. 121-128 ◽  
Author(s):  
Maria Fátima Servidoni ◽  
Carla Cristina Souza Gomez ◽  
Fernando Augusto Lima Marson ◽  
Adyléia Aparecida Dalbo Contrera Toro ◽  
Maria Ângela Gonçalves de Oliveira Ribeiro ◽  
...  

ABSTRACT Objective: The sweat test (ST) measures chloride levels in sweat and is considered the gold standard for the diagnosis of cystic fibrosis (CF). However, the reliability of a ST depends on their being performed by experienced technicians and in accordance with strict guidelines. Our aim was to evaluate how sweat stimulation, sweat collection, and chloride measurement are performed at 14 centers (9 public centers and 5 private centers) that routinely perform STs in the state of São Paulo, which has the highest frequency of CF in Brazil. Methods: This was a cross-sectional cohort study, using a standardized questionnaire administered in loco to the staff responsible for conducting STs. Results: No uniformity regarding the procedures was found among the centers. Most centers were noncompliant with the international guidelines, especially regarding the collection of sweat (the samples were insufficient in 10-50% of the subjects tested); availability of stimulation equipment (which was limited at 2 centers); modernity and certification of stimulation equipment (most of the equipment having been used for 3-23 years); and written protocols (which were lacking at 12 centers). Knowledge of ST guidelines was evaluated at only 1 center. Conclusions: Our results show that STs largely deviate from internationally accepted guidelines at the participating centers. Therefore, there is an urgent need for standardization of STs, training of qualified personnel, and acquisition/certification of suitable equipment. These are essential conditions for a reliable diagnosis of CF, especially with the increasing demand due to newborn screening nationwide, and for the assessment of a possible clinical benefit from the use of modulator drugs.


2014 ◽  
Vol 35 (3) ◽  
pp. 82-89 ◽  
Author(s):  
Carolina Bueno Somense ◽  
Erika Christiane Marocco Duran

The present study aimed to identify hygienic and motivational factors in the nursing work according to the Two-Factor Theory, as well as their relation with professional satisfaction/dissatisfaction. This exploratory-descriptive study involved nine nurses from the cardiology ward of a hospital in the interior of the State of São Paulo, between August and September 2013. A self-applied questionnaire was used, including open and closed questions. The data were categorized as hygienic and motivational. Results show the nurses' satisfaction with autonomy, work itself and teamwork, duties, content and responsibilities of the job. Dissatisfaction is related to career growth possibilities; work, political and administrative conditions at the institution, supervision and lack of institutional support. Satisfaction and dissatisfaction factors include relationships, acknowledgements and remuneration. Nurses' satisfaction is determined by multiple and often controversial factors.


2021 ◽  
Author(s):  
Isaac Rêgo Purificação ◽  
Allêh Kauãn Santos Nogueira ◽  
Matheus Araújo de Souza ◽  
João Vitor Lopes Lima ◽  
Douglas Mateus Pereira Jorge ◽  
...  

Background: The incidence of Cerebrovascular Diseases (CVD) increases significantly with age, being more frequent in the elderly. For this reason, there are still few studies that describe the epidemiological profile of these pathologies in youn g adults. Methods and Objective: From the data collected prospectively and allocated on the TabNet platform (DataSUS, MS), an observational, descriptive and cross-sectional study was carried out. As a primary objective, we seek to describe the demographic information most associated with CVD mortality in individuals between 20 and 49 years old, in São Paulo. Results: The year 2011 emerged in relation to mortality, with 1,432 deaths; in the 2010- 2019 period, the average number of deaths (± standard deviation [SD]) was 1,318 (± 61), per year. In this period, the number of deaths was higher in the capital (4,605; 34.9% of the total in the state). The mean deaths (± SD), per year, in the capital and in the interior cities were, respectively: 442 (± 58) and 2.4 (± 6.2). People with schooling from 4 to 7 years old and from 8 to 11 years old were the most affected. The ratio of male deaths to female deaths was 1.05. Conclusion: There is relative stability in relation to mortality per year among young adults in the state of SP, the capital being the city with the highest number of deaths. Male individuals, with a medium level of education were responsible for most of the deaths.


2014 ◽  
Vol 23 (1) ◽  
pp. 21-28 ◽  
Author(s):  
Bruna Pedroso Canever ◽  
Marta Lenise do Prado ◽  
Vânia Marli Schubert Backes ◽  
Mônica Motta Lino

The aim of this documentary, quantitative, exploratory and descriptive study was to characterize research groups in nursing education in the state of São Paulo and the conformity of its researchers and scientific works. Data were collected in Directory Groups of CNPq, in the 2008 census and in the Lattes platform. São Paulo has 12 Research Groups in Nursing Education, with 94 researchers, of which 91.5% are research fellows, or have a Ph.D or a master's degree. These groups have published 875 scientific articles, 62 books, 191 book chapters and 96 full papers in event annals. A total of 88.8% of scientific articles were published in Brazilian journals with Qualis/CAPES A2. São Paulo stands out in the Brazilian setting for having the largest number of research groups, qualified researchers and high-quality publications. These facts are directly related to high federal and state investments.


2010 ◽  
Vol 8 (4) ◽  
pp. 433-436 ◽  
Author(s):  
Ary Serpa Neto ◽  
Marcos Tobias-Machado ◽  
Marcelo Langer Wroclawski ◽  
Marco Akerman ◽  
Antônio Carlos Lima Pompeo ◽  
...  

ABSTRACT Objective: Prostate cancer is the second most common neoplasm among men worldwide. This study aimed to examine the trend in mortality rates of prostate cancer among the population in the state of São Paulo, Brazil, from 1980 to 2007. Methods: a descriptive study of temporal series was conducted using mortality data due to prostate cancer between1980 and 2007 in the state of São Paulo. Mortality rates were obtained from the SUS Information System on Mortality (SIM/SUS – DATASUS). The age-specific mortality rates were calculated as well as linear regression and temporal trend analysis. Results: It could be observed that mortality increased according to age, being very similar only between the age group 70-79 years and ≥ 80 years (p = 0.047). The mortality peak in the age group 50-79 years occurred at the same time; however, the drop in mortality rates since then has been much more pronounced in the group of 50-59 years. There was a linear increase and direct association between the number of biopsies and the incidence of prostate cancer (r = 0.714, p = 0.024). Conclusions: Prostate cancer is a major cause of mortality in São Paulo and effective screening and treatment measures should be adopted to improve this scenario.


Sign in / Sign up

Export Citation Format

Share Document