scholarly journals Effectiveness of Russian current in bone regeneration process in rats

2017 ◽  
Vol 30 (2) ◽  
pp. 329-336
Author(s):  
Renata Aparecida de Oliveira Lima ◽  
Ana Paula Coelho Figueira Freire ◽  
Alcides Guimarães ◽  
Caroline Pereira Santos ◽  
Francis Lopes Pacagnelli
Keyword(s):  
Bone Tissue ◽  
Tissue Repair ◽  
Low Cost ◽  
Intervention Group ◽  
Average Frequency ◽  
Repair Process ◽  
Control Group ◽  
Stimulation Protocol ◽  
Treatment Results ◽  
Adult Rats

Abstract Introduction: Russian current is an electric current of average frequency that is able to restore the properties of skeletal muscle at a low treatment cost. It is essential to know the effects of Russian current in bone tissue, since electromagnetic energy could be an efficient and low cost method to treat bone disorders. Objective: The aim of the study was to evaluate the effectiveness of Russian current in the consolidation of tibia fracture in adult rats. Methods: 24 adult male Albinus Wistar rats wereused. The animals were divided randomly into two groups: control group (CG), composed of 12 animals, and Intervention Group (IG) consisting of 12 animals, both groups were submitted to osteotomy (proximal medial surface of the tibia). The IG underwent an electrical stimulation protocol with Russian current, while the CG did not undergo any kind of intervention. Euthanasia was performed in three animals of each group on the following days: 5, 10, 20, and 30 days of treatment. Results: The results suggested higher primary ossification, intense osteogenic activity, and increased thickness of the periosteum, characterizing more advanced ossification and a greater presence of trabecular bone marrow in rats in the group subjected to the treatment. In this way, we can assign one more beneficial effect to interventions with Russian current, for the treatment of postfracture rehabilitation. Conclusion: In both groups the bone tissue repair process occurred, but in the electrically stimulated group the osteogenesis process was more advanced.

P578Use of a smartphone application to increase adherence to medical treatment in patients with acute coronary syndrome: a randomized clinical trial

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
C M Garmendia ◽  
P Miranda ◽  
E Verello ◽  
M A Goyeneche ◽  
J F Furmento ◽  
...  
Keyword(s):  
Medication Adherence ◽  
Medical Treatment ◽  
Low Cost ◽  
Intervention Group ◽  
Standard Of Care ◽  
Smartphone Application ◽  
Secondary Outcome ◽  
Control Group ◽  
Post Discharge ◽  
Coronary Syndrome

Abstract Background Adherence to cardiovascular medications following acute coronary syndrome (ACS) hospitalization is generally poor and is associated with increased risk of rehospitalization and mortality. There are still significant opportunities to identify simple and low-cost interventions that improve medication adherence and clinical outcomes. Purpose To evaluate the use of a digital platform for smartphones to improve adherence to medical treatment and outcomes for 90-days post discharge in patients hospitalized for ACS with or without ST-elevation. Methods This was a unicentric, single-blinded, randomized controlled trial enrolling 90 patients with an ACS event requiring hospitalization. The intervention consisted of a smartphone application which allowed for the loading of medication prescription together with reminder of the daily compliance. Patients in the intervention group (n=46) were equipped with the smartphone application. Patients in the control group (n=44) received written and oral instructions as per standard of care. The primary outcome was adherence to medical treatment measured at 90-days post discharge using the 8-item Morisky Medication Adherence Scale (MMAS-8). The secondary outcome was a composite of re-hospitalizations for ACS, consultations to the emergency department (ED), or unplanned visits to the clinic. Results The mean age of the population was 63.2±9.9 and 75.6% were male. At 90 days, 64.7% of patients using the smartphone application were adherent compared with 20.5% of patients in the control group (p<0.001). Patients in the intervention group had higher adherence (mean MMAS-8 score 7.52±1.25) compared with the control group (mean MMAS-8 score 6.47±1.23; p<0.001). The secondary outcome measures showed that there were no significant differences in patients using the smartphone application versus the standard of care (4.3% vs 15.9%, p=0.07, respectively). Table 1 Variables Global (n=90) Control (n=44) Intervention (n=46) p MMAS-8 score 7±1.34 6.47±1.23 7.52±1.25 <0.001 Adherents 40 (44.4%) 9 (20.5%) 31 (67.4%) <0.001 Events 9 (10.1%) 7 (15.9%) 2 (4.3%) 0.071 ED consultations 9 7 2 Score assessment 8.85±1.4 Conclusions In patients with ACS, the use of a smartphone application increased the medication adherence compared with the standard of care. These data suggest that there is potential for a simple, low-cost intervention to help patients adhere to medications. ClinicalTrials.gov unique identifier: NCT03766789.

Avaliação do Efeito da Microcorrente na Reparação de Feridas Cutâneas em Ratos

UNICIÊNCIAS ◽  
2018 ◽  
Vol 22 (2) ◽  
pp. 62
Author(s):  
Belle Virginia Da Silva Coimbra Rodrigues ◽  
Suellen Borges de Souza ◽  
Thayanne Caroline Pereira Munhoz ◽  
Gracieli Nonato Bressanin ◽  
Alessandra Aparecida Cunha Lopes ◽  
...  
Keyword(s):  
Tissue Repair ◽  
Specific Treatment ◽  
Low Frequency ◽  
Repair Process ◽  
Skin Lesions ◽  
Treated Group ◽  
Therapeutic Modality ◽  
Cervical Region ◽  
Control Group ◽  
And Control

A bioeletricidade tem se tornado cada vez mais reconhecida no mundo científico devido a sua importante contribuição na cicatrização de feridas. Dentro desta modalidade terapêutica está inserida a terapia com microcorrente, que por ter baixa frequência e pequena intensidade é capaz de promover o restabelecimento do potencial elétrico das células. Por se tratar de uma corrente de elevado potencial, durante o processo de reparação tecidual, esta pode atuar tanto na fase inflamatória quanto na proliferativa. Dessa maneira, este estudo teve por objetivo principal avaliar a resposta cicatricial quanto ao efeito da microcorrente em lesões cutâneas em ratos. Para tanto, foram utilizados 28 ratos Wistar, divididos em dois grupos: grupo tratado (GT) e grupo controle (GC). Os animais de ambos os grupos foram submetidos a procedimento cirúrgico de lesão cutânea região cervical dorsal, seguido de tratamento com microcorrente durante 21 dias no GT, e sem tratamento específico no GC. Também foi realizada a avaliação termográfica a cada três dias de todos os animais. Após este período, foi feita eutanásia com posterior coleta de pele na região da lesão para avaliação histopatológica. Os resultados obtidos mostraram, a partir dos parâmetros analisados, a presença de um recurso capaz de incrementar a formação de novos vasos, embora não apresentasse efeito significativo em relação à proliferação de fibroblastos. Diante disso, sugere-se que a utilização da microcorrente possa ter favorecido a neovascularização nos tecidos dos animais analisados. Palavras-chave: Rato. Microcorrente. Angiogênese. Reparo tecidual. AbstractBioelectricity has become increasingly recognized in the scientific world because of its important contribution to wound healing. Within this therapeutic modality the therapy with microcurrent is inserted, which because of low frequency and small intensity is able to promote the reestablishment of the cells electric potential. Because it is a  high potential v during the tissue repair process, it can act both in the inflammatory and proliferative phases. Thus, this study had as main objective to evaluate the healing response regarding the microcurrent effect  on rats’ skin lesions. For this, 28 Wistar rats were divided into two groups: treated group (GT) and control group (CG). The animals of both groups underwent a surgical procedure of skin lesion in the dorsal cervical region, followed by treatment with microcurrent for 21 days in the GT, and without specific treatment in the CG. A thermographic evaluation was also performed every three days of all the animals. After this period, euthanasia was performed with subsequent skin collection in the lesion region for histopathological evaluation. The obtained results showed, from the analyzed parameters, the presence of a resource able to increase the  new vessels formation, although it did not present significant effect in relation to the  fibroblasts proliferation. Therefore, it is suggested that the use of microcurrent may have favored neovascularization in the tissues of the animals analyzed.Keywords: Mouse. Microcurrent. Angiogenesis. Tissue repair. 

Perioperative Intranasal Mupirocin for the Prevention of Surgical-Site Infections: Systematic Review of the Literature and Meta-Analysis

2005 ◽  
Vol 26 (12) ◽  
pp. 916-922 ◽  
Author(s):  
Alexander J. Kallen ◽  
Chad T. Wilson ◽  
Robin J. Larson
Keyword(s):  
Systematic Review ◽  
Surgical Site Infection ◽  
Low Cost ◽  
Meta Analysis ◽  
Intervention Group ◽  
Surgical Site Infections ◽  
Control Group ◽  
Site Infection ◽  
Before And After ◽  
Intranasal Mupirocin

AbstractObjective:To review the evidence evaluating perioperative intranasal mupirocin for the prevention of surgical-site infections according to type of surgical procedure.Design:Systematic review and meta-analysis of published clinical trials.Setting:Studies included were either randomized clinical trial or prospective trials at a single institution that measured outcomes both before and after an institution-wide intervention (before-after trial). In all studies, intervention and control groups differed only by the use of perioperative intranasal mupirocin in the intervention group.Patients:Patients undergoing general or nongeneral surgery (eg, cardiothoracic surgery, orthopedic surgery, and neurosurgery).Main Outcome Measure:Risk of surgical-site infection following perioperative intranasal mupirocin versus usual care.Results:Three randomized and four before-after trials met the inclusion criteria. No reduction in surgical-site infection rate was seen in randomized general surgery trials (summary estimates: 8.4% in the mupirocin group and 8.1% in the control group; relative risk [RR], 1.04; 95% confidence interval [CI95], 0.81 to 1.33). In nongeneral surgery, the use of mupirocin was associated with a reduction in surgical-site infection in randomized trials (summary estimates: 6.0% in the mupirocin group and 7.6% in the control group; RR, 0.80; CI95, 0.58 to 1.10) and in before-after trials (summary estimates: 1.7% in the mupirocin group and 4.1% in the control group; RR, 0.40; CI95, 0.29 to 0.56).Conclusions:Perioperative intranasal mupirocin appears to decrease the incidence of surgical-site infection when used as prophylaxis in nongeneral surgery. Given its low risk and low cost, use of perioperative intranasal mupirocin should be considered in these settings.

scholarly journals Effects of dimethylsulfoxide and pentoxifylline in the vitality of cutaneous flaps in rats

2017 ◽  
Vol 44 (5) ◽  
pp. 457-464 ◽  
Author(s):  
Stephanie Luzia da Costa Pedretti ◽  
Cícero de Lima Rena ◽  
Maria Christina Marques Nogueira Castãnon ◽  
Ana Paula do Nascimento Duque ◽  
Fernando Henrique Pereira ◽  
...  
Keyword(s):  
Single Dose ◽  
Tissue Repair ◽  
Wistar Rats ◽  
Inflammatory Infiltrate ◽  
Histological Analysis ◽  
Distal Segment ◽  
Repair Process ◽  
Control Group ◽  
Skin Flaps ◽  
Cutaneous Flap

ABSTRACT Objectives: to verify the influence of dimethylsulfoxide and pentoxifylline on the vitality of cutaneous flaps in rats and the tissue repair process. Methods: were studied 30 Wistar rats, submitting them to a 2cm wide by 8cm long dorsal cutaneous flap, of caudal base. We distributed the animals in three groups: Control Group (n=10) with application gauze moistened with 0.9% Saline in the flap bed for 30 seconds; Dimethylsulfoxide group (n=10), with administration of 1ml of 5% dimethylsulfoxide divided into five injections of 0.2ml in the transition of the flap segments; Pentoxifylline group (n=10), with administration of pentoxifylline 20mg/kg, diluted to 1ml and divided into five injections of 0.2ml in the transition of the flap segments. Drugs were administered intraoperatively, in a single dose and subcutaneously. We observed the skin flaps for changes in color and texture. On the 10th postoperative day, we checked the dimensions of viable and necrotic tissues, followed by excision of the specimen for histological analysis. Results: the measurements of length of the viable and necrotic tissues between groups showed no differences. Histological analysis showed that the Dimethylsulfoxide group presented neovascularization, inflammatory infiltrate with leukocytes and more structured conjunctival stroma. The Pentoxifylline group showed neovascularization and inflammatory infiltrate, with moderate to intense granulation. The control group evolved with a higher rate of necrosis in the distal segment. Conclusion: dimethylsulfoxide and pentoxifylline influenced the vitality of the flap and the tissue repair process. However, they did not prevent necrosis macroscopically.

scholarly journals The photobiomodulation (658, 830 and 904nm) on wound healing in histomorphometric analysis

2020 ◽  
Vol 33 ◽  
Author(s):  
Letícia Sandis Barbosa ◽  
Julia Risso Parisi ◽  
Lucas do Carmo Viana ◽  
Marcella Bernucci Carneiro ◽  
Josie Resende Torres da Silva ◽  
...  
Keyword(s):  
Tissue Repair ◽  
Repair Process ◽  
Skin Lesions ◽  
Volume Density ◽  
Collagen Fibers ◽  
Control Group ◽  
Type Iii Collagen ◽  
Type Iii ◽  
Significant Difference ◽  
Injured Region

Abstract Introduction: Photobiomodulation (PBM) assists in the processes of angiogenesis and cellular mitosis after skin lesion, contributing to tissue repair. Objective: to investigate the effects of photobiomodulation (during the proliferative phase) of 658 nm, 830 nm and 904 nm in the repair of skin lesions in an animal model. Method: 658 nm (G658), 830 nm (G830), 904 nm (G904) PBM, and control group (CG) integrated the research. We submitted the animals to an excisional wound and treatment at different wavelengths for 14 days. On the seventh and 14-1485004059th postoperative days, we calculated the area and percentage of lesion contraction. The animals were sacrificed on the 14-1485004056th postoperative day and cutaneous section of the injured region was collected for histomorphometric evaluation of the cellularity, neovascularization, thickness of the epidermis and volume density of collagen fibers colored with H&E and Picross Sirius respectively. For the statistical analysis, we applied the ANOVA test. Results: the G658 presented higher cellularity than GC (p = 0.03). The animals in the G658 group showed a significant increase in the neovascularization in relation to the CG (p = 0.01). Type III collagen significantly increased in G904 compared to G830 (p < 0.0001) and CG (p < 0.0001). The G658 had a significant increase in type III collagen fibers compared to G830 (p < 0.0001) and GC (p < 0.0001). We found no significant difference in the thickness of the epidermis, wound area, and in the percentage wound of contraction between the analyzed groups. Conclusion: PBM was effective to stimulate the tissue repair process, with better results for the 658 nm wavelength.

scholarly journals Faecal contamination of water and fingertip-rinses as a method for evaluating the effect of low-cost water supply and sanitation activities on faeco-oral disease transmission. II. A hygiene intervention study in rural north-east Thailand

1990 ◽  
Vol 105 (2) ◽  
pp. 377-389 ◽  
Author(s):  
J. V. Pinfold
Keyword(s):  
Disease Transmission ◽  
Intervention Study ◽  
Low Cost ◽  
Intervention Group ◽  
Oral Disease ◽  
Control Group ◽  
Plastic Container ◽  
North East ◽  
Hygiene Intervention ◽  
Verbal Messages

SUMMARYAn intervention study was developed from risk-factors associated with faecooral transmission, based on the levels of contamination in stored water and fingertip-rinses from households in rural north-east Thailand. This was designed to improve: (a) handwashing, particularly before cooking/eating and after defecation; (b) washing dishes immediately after use. Verbal messages were administered to two intervention groups, one also received a plastic container with a tap to assist these activities. Indicators of compliance were the direct observation of soaking dishes and the presence of faecal streptococci from fingertip-rinses; the main outcome indicator was Escherichia coli contamination of stored water. The intervention group receiving the container was significantly better than the control for indicators of compliance (P < 0·001 and P < 0·01) and its stored water was significantly less contaminated (P < 0·001). There was no significant improvement to the other intervention group, although some features of the intervention had clearly been made available to the control group. Humidity was significantly correlated with fingertip contamination (r = 0·2; P < 0·001) and with the peak of reported diarrhoea around the beginning of the rainy season.

Exercise intervention improves quality of life in older adults after myocardial infarction: randomised clinical trial

Heart ◽  
2020 ◽  
Vol 106 (21) ◽  
pp. 1658-1664 ◽  
Author(s):  
Gianluca Campo ◽  
Elisabetta Tonet ◽  
Giorgio Chiaranda ◽  
Gianluigi Sella ◽  
Elisa Maietti ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Performance ◽  
Older Patients ◽  
Exercise Intervention ◽  
Low Cost ◽  
Intervention Group ◽  
Daily Activities ◽  
Control Group ◽  
Coronary Syndrome

ObjectiveTo establish the benefits of an early, tailored and low-cost exercise intervention in older patients hospitalised for acute coronary syndrome (ACS).MethodsThe study was a multicentre, randomised assessment of an exercise intervention in patients with ACS ≥70 years with reduced physical performance (as defined by the short physical performance battery (SPPB), value 4–9). The exercise intervention included four supervised sessions (1, 2, 3, 4 months after discharge) and home-based exercises. The control group attended a health education programme only. The outcomes were the 6-month and 1-year effects on physical performance, daily activities, anxiety/depression and quality of life. Finally, 1-year occurrence of adverse events was recorded.ResultsOverall, 235 patients with ACS (median age 76 (73–81) years) were randomised 1 month after ACS. Exercise and control groups were well balanced. Exercise intervention improved 6-month and 1-year grip strength and gait speed. Exercise intervention was associated with a better quality of life (as measured by EuroQol-visual analogue scale at 6 months 80 (70–90) vs 70 (50–80) points, p<0.001 and at 1 year 75 (70–87) vs 65 (50–80) points, p<0.001) and with a reduced perception of anxiety and/or depression (6 months: 21% vs 42%, p=0.001; 1 year 32% vs 47%, p=0.03). The occurrence of cardiac death and hospitalisation for cardiac cause was lower in the intervention group (7.5% vs 17%, p=0.04).ConclusionsThe proposed early, tailored, low-cost exercise intervention improves mobility, daily activities, quality of life and outcomes in older patients with ACS. Larger studies are needed to confirm the clinical benefit.Trial registration numberNCT03021044.

scholarly journals The Effects of Thermomechanical VICO to The Level of Pain during Vaccination

2019 ◽  
Vol 8 (1) ◽  
pp. 32-38
Author(s):  
Ika Subekti Wulandari
Keyword(s):  
Nursing Students ◽  
Emotional Experience ◽  
Low Cost ◽  
Intervention Group ◽  
Control Group ◽  
P Value ◽  
Control Group Design ◽  
Group Design ◽  
Average Pain ◽  
Psychological Perceptions

ABSTRAK Pengalaman nyeri saat injeksi vaksin akan berpengaruh terhadap persepsi psikologis mahasiswa terhadap nyeri dimasa mendatang. Nyeri merupakan pengalaman sensorik dan emosional yang tidak menyenangkan. Perlu intervensi yang optimal efektif dan efisien untuk mengatasi hal tersebut. Perawat berperan penting dalam mengatasi masalah nyeri akibat tindakan invasif dan mengurasi distres emosional pada anak dan remaja. Berbagai tehnik mengatasi nyeri saat ini banyak dikembangkan baik secara farmakologi dan nonfarmakologi. Tehnik nonfarmakologi yang murah, efektif, efisien dan mudah digunakan sangat dibutuhkan untuk mengatasi nyeri saat injeksi terutama saat vaksinasi. Salah satu metode yang digunakan adalah kombinasi antara kompres dingin dan vibrasi. Kedua metode tersebut dapat menurunkan sensasi nyeri tanpa efek samping dan berbiaya ringan. Penelitian ini bertujuan untuk mengetahui efektivitas Thermomechanical VICO (Vibration and Cold) terhadap nyeri saat injeksi vaksinasi pada mahasiswa keperawatan STIKes Kusuma Husada Surakarta yang diteliti dengan menggunakan desain postest only with control group design. Hasil penelitian menunjukkan bahwa rata-rata tingkat nyeri pada kelompok intervensi adalah 2,97 sedangkan pada kelompok kontrol adalah 4,75. Kesimpulan penelitian ini adalah pemberian Thermomechanical VICO sebelum injeksi efektif untuk menurunklan nyeri dengan nilai p value 0,000. Kata kunci : Thermomechanical, Nyeri, Vaksinasi   ABSTRACT   The experience of pain when injecting vaccines will affect students' psychological perceptions of pain in the future. Pain is an unpleasant sensory and emotional experience. Need effective and efficient optimal interventions to overcome this. Nurses play an important role in overcoming pain problems due to invasive actions and reducing emotional distress in children and adolescents. Various techniques to deal with pain are currently being developed both pharmacologically and non-pharmacologically. Cheap, effective, efficient and easy to use nonfarmacology techniques are needed to deal with pain during injection, especially during vaccination. One method used is a combination of cold compresses and vibrations. Both methods can reduce the sensation of pain without side effects and are low-cost. This study aims to determine the effectiveness of Thermomechanical VICO (Vibration and Cold) against pain during vaccination injection in nursing students of STIKes Kusuma Husada Surakarta who were studied using posttest only with control group design. The results showed that the average pain level in the intervention group was 2.97 while in the control group it was 4.75. The conclusion of this study was the provision of Thermomechanical VICO before effective injection to decrease pain levels with a p value of 0,000. Keywords : Thermomechanical, Pain, Vaccination

scholarly journals Pengaruh Terapi Humor dengan Media Film Komedi terhadap Penurunan Tekanan Darah Pada Lansia Dengan Hipertensi

2019 ◽  
Vol 4 (1) ◽  
pp. 29
Author(s):  
Dewi Masruroh ◽  
Eka Misbahatul M.Has ◽  
Rista Fauziningtyas
Keyword(s):  
Blood Pressure ◽  
Statistical Tests ◽  
Low Cost ◽  
Intervention Group ◽  
Blood Pressure Level ◽  
The Body ◽  
Control Group ◽  
P Value ◽  
Control Group Design ◽  
Kolmogorov Smirnov

Introduction: Hypertension or high blood pressure often occur without symptoms, so called the silent killer. Based on these problems, humour therapy can be used to reduce the incidence of hypertension and decrease blood pressure at low cost, easily done. Humour therapy most economical to fight against hypertension. Humour therapy also stimulates endorphins hormone. Endorphins stimulate relaxes tense muscles, blood vessels dilate to accelerate the flow of blood the body. This study was aimed to determine the effectiveness of humour therapy in decreasing blood pressure in elderly with hypertension.Method: Design study that used is quasi-experiment pretest-posttest with control group design. The sample used amounted to fifty-three respondents to the intervention group by random sampling. The instrument used sphygmomanometer. Independent variable was humour therapy by using comedy film, and dependent variable was blood pressure. Data analysed by Wilcoxon Signed Ranks Test and Kolmogorov Smirnov with significant value p=0.05. Result: Statistical tests of Wilcoxon Signed Ranks Test on treatment group showed p-value systole 0.000 and p-value diastole 0.002. Kolmogorov Smirnov test showed the result p-value systole 0.000 and p-value diastole 0.815, which means there was change of systole blood pressure level before and after humour therapy by using comedy film.Conclusion: Humor Therapy affects decreased in systolic blood pressure in the elderly with hypertension. humour therapy can be used as an alternative choice to reduce the incidence of hypertension

scholarly journals The addition of mobile SMS effectively improves dengue prevention practices in community: an implementation study in Nepal

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Ashmin Hari Bhattarai ◽  
Guardian Yoki Sanjaya ◽  
Anil Khadka ◽  
Randeep Kumar ◽  
Riris Andono Ahmad
Keyword(s):  
Low Cost ◽  
Intervention Group ◽  
Shared Responsibility ◽  
Control Group ◽  
Enabling Factors ◽  
Promising Tool ◽  
Sms Intervention ◽  
Dengue Prevention ◽  
Dengue Control ◽  
Private Network

Abstract Background Dengue is an emerging vector disease with frequent outbreaks in Nepal that pose a major threat to public health. Dengue control activities are mostly outbreak driven, and still lack systematic interventions while most people have poor health-related knowledge and practices. Mobile Short Message Service (SMS) represents a low-cost health promotion intervention that can enhance the dengue prevention knowledge and practices of the affected communities. This study aimed to explore the acceptability, appropriateness, and effectiveness of mobile SMS intervention in improving dengue control practices. Methods This study was an implementation research that used mixed-methods design with intervention. A total of 300 households were divided into three groups, i.e. one control group, one dengue prevention leaflet (DPL) only intervention group and one DPL with mobile SMS intervention group (DPL + SMS). We used a structured questionnaire to collect information regarding participants’ knowledge and practice of dengue prevention. We conducted in-depth interviews with key informants to measure acceptability and appropriateness of intervention. Mean difference with standard deviation (SD), one-way ANOVA, paired t-test and regression analyses were used to assess the effectiveness of the interventions. Thematic analysis was used to assess the acceptability, and appropriateness as well as barriers and enablers of the intervention. Results The DPL + SMS intervention produced significantly higher mean knowledge difference (32.7 ± 13.7 SD vs. 13.3 ± 8.8 SD) and mean practice difference (27.9 ± 11.4 SD vs 4.9 ± 5.4 SD) compared to the DPL only group (p = 0.000). Multivariate analysis showed that the DPL + SMS intervention was effective to increase knowledge by 28.6 points and practice by 28.1 points compared to the control group. The intervention was perceived as acceptable and appropriate by the study participants and key stakeholders. Perceived barriers included reaching private network users and poor network in geographically remote areas, while enabling factors included mobile phone penetration, low cost, and shared responsibility. Conclusions Mobile SMS is an effective, acceptable and appropriate health intervention to improve dengue prevention practices in communities. This intervention can be adopted as a promising tool for health education against dengue and other diseases.

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