scholarly journals Validity of the Katz Index to assess activities of daily living by informants in neuropathological studies

2015 ◽  
Vol 49 (6) ◽  
pp. 944-950 ◽  
Author(s):  
Renata Eloah de Lucena Ferretti-Rebustini ◽  
Marcos Alencar Abaide Balbinotti ◽  
Wilson Jacob-Filho ◽  
Flávio Rebustini ◽  
Claudia Kimie Suemoto ◽  
...  

Abstract OBJECTIVE To analyze the evidences of construct validity of the Katz Index for the retrospective assessment of activities of daily living (ADL) by informants, to assist neuropathological studies in the elderly. METHOD A cross-sectional study analyzed the functional ability of ADL measure by the Katz Index, of 650 cases randomly selected from the Brazilian Brain Bank of the Ageing Brain Study Group (BBBABSG) database. Sample was divided in two subsamples for the analysis (N=325, each) and then stratified according to cognitive decline assessed by the Clinical Dementia Rating Scale (CDR). Factor analyses with calculations of internal consistency and invariance were performed. RESULTS Factor analysis evidenced a unidimensional instrument with optimal internal consistency, in all subgroups. Goodness of fit indices were obtained after two treatments of covariance, indicating adequacy of the scale for assessing ADL by informants. The scale is invariant to cognitive decline meaning that it can be used for subjects with or without cognitive impairment. CONCLUSION Katz Index is valid for the retrospective assessment of basic ADL by informants, with optimal reliability.

2018 ◽  
Vol 3 (1) ◽  
pp. 31-38
Author(s):  
W Ibowo

Proses penuaan yang dialami lansia tidak hanya berhubungan pada segi kehidupan tetapi juga akan diikuti dengan kemunduran fisik dan mental. Gangguan mental yang sering dijumpai pada lansia adalah kecemasan dan depresi serta gangguan faal tubuh. Tingkat depresi itu sendiri berbeda-beda pada setiap lansia. Saat memasuki usia tua, para lansia memiliki perubahan struktur otak yang menyebabkan kemunduran kualitas hidup yang berimplikasi pada kemandirian dalam melakukan aktivitas sehari-hari atau ADL (Activities of Daily Living). Metode penelitian menggunakan penelitian deskriptif korelasi dengan desain penelitian cross sectional yang bertujuan untuk melihat  hubungantingkat depresi  lansia terhadap tingkat kemandirian lansia dalam pemenuhan kebutuhan Activity Daily Living (ADL). Populasi dalam penelitian ini adalah para lansia yang datang ke posyandu,tehnik sampling yang digunakan adalah total sampling dengan jumlah sampel sebanyak 76 responden  dengan menggunakan alat ukur Geriatric Depression Scale (GDS) dan KATZ Index. Uji statistik yang digunakan adalah uji statistik non parametrik, yaitu uji Korelasi Rank Spearmen menggunakan aplikasi SPSS 20 for nilai signifikansi atau Sig. (2-tailed) sebesar 0,413. Karena nilai Sig. (2-tailed) 0,413 > 0,05 level (2-tailed) maka artinya tidak ada hubungan yang signifikan antara tingkat depresi dengan tingkat kemandirian pada lansia.   Kata Kunci: Depresi, Activities of Daily Living, Lansia


2019 ◽  
Vol 35 ◽  
pp. 153331751987139 ◽  
Author(s):  
Daiki Ishimaru ◽  
Hiroyuki Tanaka ◽  
Yuma Nagata ◽  
Shinichi Takabatake ◽  
Takashi Nishikawa

Background: The authors examined associations between physical activity, cognitive function, activities of daily living, and behavioral and psychological dementia symptoms (BPSD) in severe and moderate dementia. Methods: A cross-sectional study was conducted to assess severe and moderate dementia groups according to the Clinical Dementia Rating. An actigraphy measured physical activity. Other measures included Mini-Mental State Examination, Cognitive Test for Severe Dementia, Hyogo Activities of Daily Living Scale, and Neuropsychiatric Inventory-Nursing Home. Results: Sixty-three participants were assessed (mean age = 89.3 ± 6.4). Physical activity was not associated with cognitive function among participants with severe dementia, although there was a trend-level association with cognitive function among those with moderate dementia. Physical activity was significantly associated with BPSD, specifically agitation/aggression symptoms, for participants with severe dementia, and there was a trend-level association with anxiety for participants with moderate dementia. Conclusions: Physical activity appears to be associated with BPSD among individuals in the advanced stages of dementia.


2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Shunsuke Sato ◽  
Mamoru Hashimoto ◽  
Kenji Yoshiyama ◽  
Hideki Kanemoto ◽  
Maki Hotta ◽  
...  

Abstract Background This study aimed to clarify the neuropsychiatric symptoms of right-sided predominant semantic dementia (SD-R) by comparing them with those of behavioral variant frontotemporal dementia (bvFTD), left-sided predominant SD (SD-L), and Alzheimer’s disease (AD). This study also aimed to identify clinical factors related to caregiver burden for bvFTD, SD-R, and SD-L. Methods The neuropsychiatric symptoms of 28 patients with bvFTD, 14 patients with SD-R, 24 patients with SD-L, and 43 patients with AD were evaluated using the Neuropsychiatric Inventory (NPI) and the Stereotypy Rating Inventory (SRI). Cognitive function was assessed using the Mini-Mental State Examination (MMSE). Dementia severity was assessed using the Clinical Dementia Rating. Activities of daily living were assessed using the Lawton Instrument Activities of Daily Living (IADL) scale and the Physical Self-Maintenance Scale. We compared the NPI and SRI scores among the four groups using the Kruskal-Wallis test. In addition, clinical factors related to caregiver burden, represented by the Japanese version of the Zarit Burden Interview (J-ZBI), were analyzed using multiple regression analysis in the bvFTD, SD-R, and SD-L groups. Results The NPI total score and the NPI subscale scores of apathy and disinhibition were significantly higher in the bvFTD group than in the SD-L and AD groups. The SD-R group scores were closer to those of the bvFTD group than the SD-L group. The SRI total score and SRI subscale scores for eating and cooking and speaking were significantly higher in the bvFTD, SD-R, and SD-L groups than in the AD group. The NPI total score was significantly associated with the J-ZBI score in the bvFTD group. The NPI total score and Lawton IADL scale score were independently associated with the J-ZBI score in the SD-R group. Furthermore, the NPI total score and MMSE score were independently associated with the J-ZBI score in the SD-L group. Conclusions SD-R seemed to be a similar condition to bvFTD rather than SD-L regarding behavioral symptoms. Our results suggest that each frontotemporal dementia subgroup requires different approaches to reduce the caregiver burden.


Author(s):  
Mohamed Tanveer Ahmed ◽  
Jyothi Jadhav ◽  
Ranganath Timmanahalli Sobagaiah ◽  
Vishwanatha .

Background: Developing countries including India are in epidemiologic health transition resulting in increased life expectancy and increase in geriatric population. Geriatric population is considered the most vulnerable population. Many factors such as age, income, education, environment have a significant impact on quality of life. Hence our study aims at assessing the Quality of life and activities of daily living among geriatric population in Bengaluru city. Methods: A cross sectional study was carried out for a period of 3 months - August to October 2016 among 250 geriatric study participants residing in the slums of Bangalore. Data was collected using WHOQOL-BREF scale and Katz Index of Independence of Activities of Daily Living by interview method. Results: Out of 250 study participants, males were 127 (50.8%) and females were 123 (49.2%). Quality of life was found to be average with a mean score of 50.02 (11.13) and with a least score of 44.55 (12.54) for environmental domain. Conclusions: Significant association was found between quality of life and factors like age, functional capacity, education and environment. Improving access of elderly to health facilities, providing health education, psychological support, and modification of environment helps to improve the quality of life among aged population. 


Neurology ◽  
2001 ◽  
Vol 57 (3) ◽  
pp. 481-488 ◽  
Author(s):  
R. C. Mohs ◽  
R. S. Doody ◽  
J.C. Morris ◽  
J. R. Ieni ◽  
S. L. Rogers ◽  
...  

Objective: To examine the effects of donepezil compared with placebo on the preservation of function in patients with AD over a 1-year period.Methods: This was a prospective, 54-week, double-blind, placebo-controlled, survival to endpoint study. Patients were required to have at entry: a diagnosis of probable AD (National Institute of Neurological and Communicative Disorders and Stroke criteria); Mini-Mental State Examination score of 12 to 20; Clinical Dementia Rating of 1 or 2; modified Hachinski ischemia score ≤4; and capability of performing 8 of 10 instrumental activities of daily living and 5 of 6 basic activities of daily living. Patients (n = 431) were randomized to placebo or donepezil (5 mg/day for 28 days, 10 mg/day thereafter). Outcome measures were the AD Functional Assessment and Change Scale, the Mini-Mental State Examination, and Clinical Dementia Rating scale. At each visit, investigators determined whether predefined criteria for clinically evident decline in functional status had been met. Patients who met the endpoint criteria were discontinued per protocol.Results: Donepezil extended the median time to clinically evident functional decline by 5 months versus placebo. The probability of patients treated with donepezil remaining in the study with no clinically evident functional loss was 51% at 48 weeks, compared with 35% for placebo. The Kaplan–Meier survival curves for the two treatment groups were different (p = 0.002, log-rank test).Conclusions: Patients with AD continue to show detectable disease progression over time, but treatment with donepezil for 1 year was associated with a 38% reduction in the risk of functional decline compared with placebo.


2007 ◽  
Vol 29 (4) ◽  
pp. 350-353 ◽  
Author(s):  
Jefferson C Folquitto ◽  
Sonia E Z Bustamante ◽  
Sérgio B Barros ◽  
Dionisio Azevedo ◽  
Marcos A Lopes ◽  
...  

OBJECTIVES: To investigate the applicability of the Bayer - Activities of Daily Living scale and its efficiency in differentiating individuals with mild to moderate dementia from normal elderly controls. METHOD: We selected 33 patients with diagnosis of mild to severe dementia, according to ICD-10 criteria, and 59 controls. All the subjects were evaluated with the Mini-Mental State Examination and the Clinical Dementia Rating Scale and the Bayer - Activities of Daily Living scale was applied to informants. RESULTS: The internal consistency of the Bayer - Activities of Daily Living was high (Cronbach's alpha = 0.981). Mean Mini-Mental State Examination and Bayer - Activities of Daily Living scores of demented patients and controls were significantly different (p < 0.001). Mean Mini-Mental State Examination and Bayer - Activities of Daily Living scores were significantly different between Clinical Dementia Rating Scale 0 (controls; n = 59) versus Clinical Dementia Rating Scale 1 (mild dementia; n = 15), Clinical Dementia Rating Scale 0 versus Clinical Dementia Rating Scale 2 (moderate dementia; n = 13), and for Clinical Dementia Rating Scale 1 versus Clinical Dementia Rating Scale 2 (p < 0.003). DISCUSSION: The Bayer - Activities of Daily Living scale and Mini-Mental State Examination differentiated elderly controls from patients with mild or moderate dementia, and patients with mild dementia from those with moderate dementia. CONCLUSIONS: The results suggest that the Bayer - Activities of Daily Living scale applied to an informant can help in the diagnosis and follow-up of Brazilian patients with mild to moderate dementia.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Mon S. Bryant ◽  
Gu Eon Kang ◽  
Elizabeth J. Protas

Abstract Background Many persons living with Parkinson’s disease (PD) have difficulty rising from a chair. Impaired ability to perform the chair rise may be associated with low physical activity levels and reduced ability to perform activities of daily living (ADL). Methods Cross-sectional analysis was performed in 88 persons with PD to study the association of chair rising ability with ADL and physical activity. Results We found that the participants who pushed themselves up from the chair had more severe PD, higher motor impairment and more comorbidity than those who rose from a chair normally. The Unified Parkinson’s Disease Rating Scale ADL (UPDRS-ADL), Schwab and England Activities of Daily Living Scale (SE-ADL) and the Physical Activity Scale for the Elderly (PASE) scores for the participants who pushed themselves up to rise (17.20 ± 7.53; 76.67 ± 13.23; 46.18 ± 52.64, respectively) were significantly poorer than for those who rose normally (10.35 ± 3.79; 87.64 ± 8.30; 112.90 ± 61.40, respectively) (all p < .05). Additionally, PASE scores were significantly poorer for participants who pushed themselves up to rise compared to those who rose slowly (95.21 ± 60.27) (p < .01). Pushing up to rise from a chair was a significant predictor of UPDRS-ADL (β = .357; p < .001; R2 = .403), SE-ADL (β = −.266; p = .009; R2 = .257) and PASE (β = −.250; p = .016; R2 = .162). Conclusions Ability to rise from a chair was associated with ADL limitation and physical activity in persons with PD. Poor ability to rise from a chair may prevent persons from living independently and engaging in physical activity.


2010 ◽  
Vol 68 (6) ◽  
pp. 855-861 ◽  
Author(s):  
Sheilla de Medeiros Correia ◽  
Lilian Schafirovits Morillo ◽  
Wilson Jacob Filho ◽  
Leticia Lessa Mansur

OBJECTIVE: To characterize the problems of feeding and swallowing in individuals with moderate and severe Alzheimer´s disease (AD) and to correlate these with functional aspects. METHOD: Fifty patients with AD and their caregivers participated in this study. The instruments used were: Clinical Dementia Rating (CDR), Mini-Mental State Examination, Index of Activities of Daily Living, Assessment of Feeding and Swallowing Difficulties in Dementia, Functional Outcome Questionnaire for Aphasia, and Swallowing Rating Scale. RESULTS: Problems with passivity, distraction and refusal to eat were encountered in the CDR2 group. Distraction, passivity and inappropriate feeding velocity were predominant in the CDR3 group. The problems were correlated with communication, swallowing severity of AD individuals and caregiver schooling. CONCLUSION: Given the inexorable functional alterations during the course of the disease, it is vital to observe these in patients with a compromised feeding and swallowing mechanism. The present study supplies the instruments to orient caregivers and professionals.


2019 ◽  
Vol 5 (2) ◽  
Author(s):  
Mariapaola Nastri ◽  
Giulio Bartoli ◽  
Paolo De Colle

The anticholinergic burden (ACB) is known to be associated with the worsening of functional and cognitive status. This study aims at demonstrating a correlation between the ACB and the malnutrition, given the widespread effect on the digestive tract of anticholinergic medications. From 2012 to 2018, 2843 patients were recruited among the new admissions to our Geriatric Unit. For each patient the activities of daily living (ADL), the instrumental activities of daily living (IADL), the mini mental state examination (MMSE), the cumulative illness rating scale (CIRS), the mini nutritional assessment (MNA) and the ACB of medications were evaluated. The correlations between the ACB and the ADL (P<0.001), the IADL (P<0.001), the MMSE (P<0.001) scores were confirmed, and a significant correlation was also found between the ACB and the MNA (P<0.001) score. The CIRS and the ACB scores resulted to be independent predictors of all outcomes considered, in a linear regression model adjusted for age, sex, comorbidity and number of prescribed drugs. Therefore, ACB seems to have by itself an impact on physical and cognitive functions and on nutritional status.


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Agnieszka Ćwirlej-Sozańska ◽  
Agnieszka Wiśniowska-Szurlej ◽  
Anna Wilmowska-Pietruszyńska ◽  
Bernard Sozański

Abstract Background The extension of the life span has led to an increase in the number of older people and an increase in the prevalence of disability in people over 60 years of age. The aim of this study was to assess the prevalence of ADL and IADL disability and to analyze its determinants among people aged 60 and older living in southeastern Poland. Methods This cross-sectional study was carried out among a randomly selected, representative population of people aged 60 and older living in southeastern Poland. Disability was assessed using the Katz Index of Independence in Basic Activities of Daily Living and Instrumental Activities of Daily Living. Logistic regression models were used to identify the factors related to ADLs and IADLs. For the variables that were included in the above models, their clustered influence on the increase in the odds ratio for the occurrence of an ADL or IADL limitation was also examined. Results The research results show that 35.75% of the participants reported at least one problem with IADLs. At least one problem with ADLs was reported by 17.13% of the participants. The most significant modifiable factors influencing the occurrence of disability were the presence of barriers in the participant’s environment, poor relations with relatives, a lack of social contacts, multimorbidity and pain. A multiple increase in the odds ratio of disability was found with the presence of pairs of analyzed factors. The highest odds ratio of at least one ADL limitation was observed for the combination of barriers in the participant’s environment with multimorbidity (OR 74.07). With regard to IADL disability, the highest odds ratio was observed for the combination of pain on the VAS scale ≥3 points with older age (OR 19.47). Conclusions The study showed a high prevalence of ADL and IADL disability in older people living in southeastern Poland. It also indicated the extent to which modifiable factors influenced the occurrence of disability and the extent to which the risk of disability increased with the presence of pairs of factors, especially those that included environmental barriers in the participant’s environment.


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