scholarly journals Effects of dignity therapy on terminally ill patients: a systematic review

2016 ◽  
Vol 50 (6) ◽  
pp. 1014-1024 ◽  
Author(s):  
Suzana Cristina Teixeira Donato ◽  
◽  
Jéssica Yumi Matuoka ◽  
Camila Cristófero Yamashita ◽  
Marina de Goés Salvetti ◽  
...  
Keyword(s):  
Systematic Review ◽  
Search Strategy ◽  
Physical Symptoms ◽  
Inclusion Criteria ◽  
Level Of Evidence ◽  
Dignity Therapy ◽  
Literature Reviews ◽  
Will To Live ◽  
High Level

Abstract OBJECTIVE Analyzing the evidence of the effects of dignity therapy onterminally ill patients. METHOD A Systematic review of the literature conducted using the search strategy in six databases. Inclusion criteria were primary studies, excluding literature reviews (systematic or not) and conceptual articles. RESULTS Ten articles were analyzed regarding method, results and evidence level. Dignity therapy improved the sense of meaning andpurpose, will to live, utility, quality of life, dignity and family appreciationin studies with a higher level of evidence. The effects are not well established in relation to depression, anxiety, spirituality and physical symptoms. CONCLUSION Studies with a moderate to high level of evidence have shown increased sense of dignity, will to live and sense of purpose. Further studies should be developed to increase knowledge about dignity therapy.

scholarly journals EFFECT OF PILATES METHOD ON PHYSICAL FITNESS RELATED TO HEALTH IN THE ELDERLY: A SYSTEMATIC REVIEW

2019 ◽  
Vol 25 (1) ◽  
pp. 76-87
Author(s):  
Gabrielle Critine Moura Fernandes Pucci ◽  
Eduardo Borba Neves ◽  
Francisco José Félix Saavedra
Keyword(s):  
Systematic Review ◽  
Physical Fitness ◽  
The Elderly ◽  
Inclusion Criteria ◽  
Level Of Evidence ◽  
Quasi Experimental ◽  
Pilates Method ◽  
Functional Autonomy ◽  
Selection Of

ABSTRACT The objective of this review was to analyze the evidence of Pilates in physical fitness related to health in the elderly. The article indexing databases (Pubmed, Medline, Science Direct, Scielo, Lilacs, and Cochrane) were reviewed along with the Pilates, elderly and aging descriptors. A total of 41 studies with a randomized experimental and quasi-experimental design met the inclusion criteria. The selection of the studies was carried out by two researchers and the quality of the articles was assessed using the PEDro scale. Interventions ranged from 4-24 weeks with 1-3 sessions/week, and balance was the most investigated variable. The studies included in this review indicate that Pilates improves health status in the elderly, promoting gains in balance, muscle strength, flexibility, functional autonomy, muscular endurance, body composition and aerobic endurance. Despite these findings, some variables need to be further investigated. Level of Evidence II; Systematic review.

scholarly journals Are self-ligating brackets related to less formation of Streptococcus mutans colonies? A systematic review

2014 ◽  
Vol 19 (1) ◽  
pp. 60-68 ◽  
Author(s):  
Leonard Euler Andrade Gomes do Nascimento ◽  
Margareth Maria Gomes de Souza ◽  
Angela Rita Pontes Azevedo ◽  
Lucianne Cople Maia
Keyword(s):  
Systematic Review ◽  
Streptococcus Mutans ◽  
Selection Criteria ◽  
Search Strategy ◽  
Cochrane Central Register ◽  
Inclusion Criteria ◽  
Central Register ◽  
Data Collection And Analysis

OBJECTIVE: To verify, by means of a systematic review, whether the design of brackets (conventional or self-ligating) influences adhesion and formation of Streptococcus mutans colonies. METHODS: Search strategy: four databases (Cochrane Central Register of Controlled Trials, Ovid ALL EMB Reviews, PubMed and BIREME) were selected to search relevant articles covering the period from January 1965 to December 2012. Selection Criteria: in first consensus by reading the title and abstract. The full text was obtained from publications that met the inclusion criteria. Data collection and analysis: Two reviewers independently extracted data using the keywords: conventional, self-ligating, biofilm, Streptococcus mutans, and systematic review; and independently evaluated the quality of the studies. In case of divergence, the technique of consensus was adopted. RESULTS: The search strategy resulted in 1,401 articles. The classification of scientific relevance revealed the high quality of the 6 eligible articles of which outcomes were not unanimous in reporting not only the influence of the design of the brackets (conventional or self-ligating) over adhesion and formation of colonies of Streptococcus mutans, but also that other factors such as the quality of the bracket type, the level of individual oral hygiene, bonding and age may have greater influence. Statistical analysis was not feasible because of the heterogeneous methodological design. CONCLUSIONS: Within the limitations of this study, it was concluded that there is no evidence for a possible influence of the design of the brackets (conventional or self-ligating) over colony formation and adhesion of Streptococcus mutans.

scholarly journals Effectiveness of nursing interventions in preventing and treating radiotherapy side effects in cancer patients: a systematic review

2021 ◽  
Vol 55 ◽  
Author(s):  
Aline Moraes de Abreu ◽  
Duan Renato da Silva Fraga ◽  
Bruna Bastos Giergowicz ◽  
Rosália Borges Figueiró ◽  
Roberta Waterkemper
Keyword(s):  
Systematic Review ◽  
Side Effects ◽  
Oral Care ◽  
Nursing Interventions ◽  
Patient Centered ◽  
Level Of Evidence ◽  
Centered Care ◽  
Recommendation Grade ◽  
High Level

ABSTRACT Objective: To synthesize the best available evidence on the effectiveness of nursing interventions in radiotherapy patient care and to summarize the evidence on the experience and acceptability of interventions reported by health professionals involved in the prevention and treatment of side effects. Method: A mixed-method systematic review. Quantitative and qualitative studies are presented. Results: Twelve studies published between 2013 and 2017 were included. Most interventions found focused on skin care, oral care, nausea and vomiting and nursing consultation. In accordance with high level of evidence and recommendation grade of the studies, the use of Calendula officinalis and thyme honey were considered effective for preventing and treating radiodermatitis and mucositis, respectively. Conclusion: The quality of evidence of nursing interventions is weak. Although there are studies with a strong design and a high level of evidence, publication of nursing interventions is not enough and does not present a high quality to support practice to plan an effective patient-centered care.

scholarly journals Distress with Breathing in People with Lung Cancer: A Systematic Review

2009 ◽  
Author(s):  
Elizabeth Quast ◽  
Marie Williams
Keyword(s):  
Lung Cancer ◽  
Systematic Review ◽  
Daily Living ◽  
Search Strategy ◽  
Management Strategies ◽  
Common Symptom ◽  
Inclusion Criteria ◽  
Lung Cancer Patients ◽  
High Prevalence

While the prevalence of shortness of breath has been reported to be as frequent as pain in people with lung cancer, less attention has been paid to the distress associated with this symptom (dyspnea). This systematic review of the literature was undertaken to investigate how this symptom has been assessed and whether breathlessness in people with lung cancer is distressing. Using a pre-determined search strategy and inclusion criteria, thirty-one primary studies were identified and included in this review. A variety of outcome measures have been used to assess the experience of dyspnea with domains including intensity, distress, quality of life, qualitative sensation and prevalence. The distress associated with breathlessness appears to be variable, with some studies reporting it to be the most distressing sensation, while others report lower levels of distress. Overall the studies reflect a high prevalence of dyspnea in lung cancer patients, with subjects experiencing a moderate level of dyspnea intensity and interference with activities of daily living. Overall, the findings of this review indicate that dyspnea was a common symptom experienced by people with lung cancer with varying degrees of intensity and unpleasantness. Thus, if dyspnea and pain are both distressing sensations for people with lung cancer, this has potential implications for both clinical and academic areas, with regards to both management strategies and further research.

scholarly journals INTERPOSITION-ARTHROPLASTY OF THE ELBOW: SYSTEMATIC REVIEW

2021 ◽  
Vol 29 (4) ◽  
pp. 219-222
Author(s):  
THIAGO BERNARDO CARVALHO DE ALMEIDA ◽  
EDMILSON DA SILVA REIS ◽  
LUCIANO PASCARELLI ◽  
ROBERTO RANGEL BONGIOVANNI ◽  
RENATO LOUREIRO TEODORO
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Research Strategy ◽  
Inclusion Criteria ◽  
Specific Topic ◽  
Interposition Arthroplasty ◽  
Level Of Evidence ◽  
Total Arthroplasty ◽  
High Level ◽  
Positive Results

ABSTRACT Objective: To perform a systematic review of the main methods and indications of interposition arthroplasty in the rigid elbow. Methods: The research was carried out by three independent researchers, in the databases PubMed, Medline and Embase, according to the descriptors selected as a research strategy and filters selected in the inclusion criteria. Results: In total, 21 studies were found with the afore mentioned descriptors and which were considered adequate according to the design and relevance according to the type of study and inclusion filters. There was a very strong correlation between the searches of the three researchers (k = 0.809). At the end, 14 complete studies were presented, all of which were included. Conclusion: The main finding of this study was to note that there is an evident lack of research with a high level of real effectiveness and indication for interposition arthroplasty in the rigid elbow. Most studies point to positive results when the patient is young and a total arthroplasty is not indicated. No meta-analysis or randomized clinical trial was found for this specific topic, despite being a technique applied in clinical practice for some decades and showing good results. Level of Evidence V, Systematic Review.

scholarly journals Is There Any Association Between Chronic Periodontitis and Anxiety in Adults? A Systematic Review

2021 ◽  
Vol 12 ◽  
Author(s):  
Walessa Alana Bragança Aragão ◽  
de Deiweson Souza-Monteiro ◽  
Deborah Ribeiro Frazão ◽  
Yago Gecy de Sousa Né ◽  
Railson de Oliveira Ferreira ◽  
...  
Keyword(s):  
Systematic Review ◽  
Web Of Science ◽  
Case Control ◽  
Inclusion Criteria ◽  
Level Of Evidence ◽  
Clinical Trial Registration ◽  
Cross Sectional ◽  
Psychosocial Conditions ◽  
Cross Sectional Studies

Periodontitis is a multifactorial disease triggered by dysbiotic biofilms, involving the host's immune response, systemic and behavioral factors, including psychosocial conditions. This systematic review aimed to investigate the possible association between periodontitis and anxiety in adults. Searches were performed in PubMed, Scopus, Web of Science, Lilacs, Cochrane, and OpenGrey databases, without language restrictions, considering studies in adults (P-Participants), with (E-Exposure) and without periodontitis (C- Comparison) in an outcome of association with anxiety (O-outcome). Methodological quality assessment was carried out using the Newcastle-Ottawa protocol for case-control and cross-sectional studies, followed by an analysis of the level of evidence using the GRADE tool. Metanalysis was not performed due to several differences in methods applied by authors in primary studies. Eleven observational studies were selected according to the inclusion criteria from the total of 6,380 studies retrieved from databases. Eight studies demonstrated higher anxiety levels in subjects with periodontitis, among which only one study presented a high risk of bias. The GRADE tool revealed a low level of evidence for the anxiety outcome measured by the State-Trait Anxiety Inventory (STAI), both for case-control and cross-sectional studies. However, since anxiety may affect the quality of life of many subjects, it reinforces the need for further studies that evaluate this association for more extended periods.Clinical Trial Registration:PROSPERO-CRD42020190445.

The Use of a Synthetic Cartilage Implant for Hallux Rigidus: A Systematic Review

2020 ◽  
pp. 193864002093716
Author(s):  
Niall A. Smyth ◽  
Christopher D. Murawski ◽  
Charles P. Hannon ◽  
Jonathan R. Kaplan ◽  
Amiethab A. Aiyer
Keyword(s):  
Systematic Review ◽  
Polyvinyl Alcohol ◽  
Controlled Trial ◽  
Meta Analysis ◽  
Hallux Rigidus ◽  
Great Toe ◽  
Systematic Review Methodology ◽  
Level Of Evidence ◽  
High Level

Background. Hallux rigidus is a common pathology afflicting the foot, for which various joint salvage techniques have been described with a multitude of different implants. Recently, a synthetic cartilage implant composed of polyvinyl alcohol (PVA) received FDA premarket approval for the treatment of arthritis of the great toe. The purpose of this study was to (1) systematically review the clinical evidence supporting the use of a PVA implant in hallux rigidus and (2) determine the strength of the recommendation that can be made supporting the use of a PVA implant by evaluating the quality of evidence available. Methods. A systematic review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis. Using the terms “cartiva OR polyvinyl alcohol OR synthetic cartilage OR hemiarthroplasty AND hallux rigidus OR great toe arthritis OR first toe arthritis” we searched the PubMed/Medline database. The quality of the included studies was evaluated using the American Academy of Orthopaedic Surgeons Clinical Practice Guideline and Systematic Review Methodology. Results. Seven studies met the inclusion criteria, 6 of these were derived from a single randomized controlled trial. A moderate recommendation can be given for the use of a PVA implant for hallux rigidus based on short-term outcomes. A limited recommendation can be given for the use of a PVA implant for hallux rigidus based on mid-term outcomes. Conclusion. There are limited studies available detailing the outcomes of a PVA implant for hallux rigidus; however, the results that are available demonstrate a high level of evidence. Levels of Evidence: Level I: Systematic review

scholarly journals The pharmacogenetics of treatment with olanzapine

2021 ◽  
Author(s):  
Pablo Zubiaur ◽  
Paula Soria-Chacartegui ◽  
Gonzalo Villapalos-García ◽  
Juan J Gordillo-Perdomo ◽  
Francisco Abad-Santos
Keyword(s):  
Systematic Review ◽  
Genetic Polymorphism ◽  
Drug Targets ◽  
Pharmacokinetic Variability ◽  
Inclusion Criteria ◽  
Level Of Evidence ◽  
Metabolizing Enzymes ◽  
Safety And Efficacy ◽  
High Level ◽  
Actionable Variants

Genetic polymorphism in olanzapine-metabolizing enzymes, transporters and drug targets is associated with alterations in safety and efficacy. The aim of this systematic review is to describe all clinically relevant pharmacogenetic information on olanzapine and to propose clinically actionable variants. Two hundred and eighty-four studies were screened; 76 complied with the inclusion criteria and presented significant associations. DRD2 Taq1A (rs1800497) *A1, LEP -2548 (rs7799039) G and CYP1A2*1F alleles were related to olanzapine effectiveness and safety variability in several studies, with a high level of evidence. DRD2 –141 (rs1799732) Ins, A-241G (rs1799978) G, DRD3 Ser9Gly (rs6280) Gly, HTR2A rs7997012 A, ABCB1 C3435T (rs1045642) T and G2677T/A (rs2032582) T and UGT1A4*3 alleles were related to safety, effectiveness and/or pharmacokinetic variability with moderated level of evidence.

scholarly journals The quality of research on judicialization and its influence on public policies on access to medicines in Brazil: a systematic review

2021 ◽  
Vol 26 (11) ◽  
pp. 5577-5588
Author(s):  
Pollyanna Farias Castro Pereira de Lyra ◽  
Dyego Carlos Souza Anacleto de Araújo ◽  
Genival Araújo dos Santos Júnior ◽  
Bárbara Manuella Cardoso Sodré-Alves ◽  
Elisdete Maria Santos de Jesus ◽  
...  
Keyword(s):  
Systematic Review ◽  
Web Of Science ◽  
Public Policies ◽  
Access To Medicines ◽  
Inclusion Criteria ◽  
Study Selection ◽  
Final Sample ◽  
High Level ◽  
Quality Of Research

Abstract Patients without access to medicines often resort to the judicial system. However, no systematic review has discussed the quality of studies and the factors that may influence the access to medicines from judicialization. This study aimed to characterize the quality of research on access to judicialized medicines and their influence on public policies in Brazil. A search was conducted in the LILACS, PubMed/Medline, Scopus, and Web of Science databases using the terms “judicialization” and “medication”. Two reviewers identified articles that met the inclusion criteria. Only studies written in English, Portuguese, or Spanish published from 1990 to 2018 were included. The study selection resulted in a final sample of 45 articles. The retrospective descriptive design was the most common methods, based on reports and lawsuits. A high level of heterogeneity among the studies hindered the comparison and generation of evidence capable of supporting judges’ decisions based on technical-scientific criteria. This review showed that studies were heterogeneous and had low methodological quality. Moreover, they did not propose viable solutions for health managers and formulators to face the problem.

scholarly journals Prognostic factors for chronic post-surgical pain after lung or pleural surgery: a protocol for a systematic review and meta-analysis

BMJ Open ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. e051554
Author(s):  
Pascal Richard David Clephas ◽  
Sanne Elisabeth Hoeks ◽  
Marialena Trivella ◽  
Christian S Guay ◽  
Preet Mohinder Singh ◽  
...  
Keyword(s):  
Systematic Review ◽  
Prognostic Factors ◽  
Prognostic Factor ◽  
Meta Analysis ◽  
Case Series ◽  
Related Factors ◽  
Surgical Pain ◽  
Literature Reviews ◽  
Chronic Post Surgical Pain

IntroductionChronic post-surgical pain (CPSP) after lung or pleural surgery is a common complication and associated with a decrease in quality of life, long-term use of pain medication and substantial economic costs. An abundant number of primary prognostic factor studies are published each year, but findings are often inconsistent, methods heterogeneous and the methodological quality questionable. Systematic reviews and meta-analyses are therefore needed to summarise the evidence.Methods and analysisThe reporting of this protocol adheres to the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) checklist. We will include retrospective and prospective studies with a follow-up of at least 3 months reporting patient-related factors and surgery-related factors for any adult population. Randomised controlled trials will be included if they report on prognostic factors for CPSP after lung or pleural surgery. We will exclude case series, case reports, literature reviews, studies that do not report results for lung or pleural surgery separately and studies that modified the treatment or prognostic factor based on pain during the observation period. MEDLINE, Scopus, Web of Science, Embase, Cochrane, CINAHL, Google Scholar and relevant literature reviews will be searched. Independent pairs of two reviewers will assess studies in two stages based on the PICOTS criteria. We will use the Quality in Prognostic Studies tool for the quality assessment and the CHARMS-PF checklist for the data extraction of the included studies. The analyses will all be conducted separately for each identified prognostic factor. We will analyse adjusted and unadjusted estimated measures separately. When possible, evidence will be summarised with a meta-analysis and otherwise narratively. We will quantify heterogeneity by calculating the Q and I2 statistics. The heterogeneity will be further explored with meta-regression and subgroup analyses based on clinical knowledge. The quality of the evidence obtained will be evaluated according to the Grades of Recommendation Assessment, Development and Evaluation guideline 28.Ethics and disseminationEthical approval will not be necessary, as all data are already in the public domain. Results will be published in a peer-reviewed scientific journal.PROSPERO registration numberCRD42021227888.

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