scholarly journals Calculation of the efficacy of vaccines against tick infestations on cattle

2013 ◽  
Vol 22 (4) ◽  
pp. 571-578 ◽  
Author(s):  
Rodrigo Casquero Cunha ◽  
Renato Andreotti ◽  
Marcos Valério Garcia ◽  
André de Abreu Rangel Aguirre ◽  
Alexandre Leitão
Keyword(s):  
Control Method ◽  
The Other ◽  
Economic Losses ◽  
Tick Population ◽  
Scientific Publications ◽  
Cattle Ticks ◽  
Resistant Strains ◽  
Main Factors ◽  
Method Of Assessment ◽  
Vaccine Effect

Cattle ticks are responsible for great economic losses in cattle farming worldwide, and their main control method, chemicals, has been showing problems, whether resulting from the development of resistant strains of ticks or environmental contamination. Research studies directed toward developing vaccines against ticks are emerging. One way to evaluate those vaccines is to calculate the percentage of efficacy. The aim of this study was to analyze scientific publications archived in PubMed that used this method of assessment and discuss the main factors that may affect its calculation. Thus, 25 articles addressing this subject were selected. The percentage of efficacy was usually calculated in one of two ways, with one considering the reduced fertility of eggs and the other not. The latter method may underestimate the vaccine efficacy, and the most complete formula for calculating the efficacy reflects how much the vaccine actually affects the infestation. In our view, the use of the complete formula for calculating the percentage of efficacy is broader and more representative of the vaccine effect on the tick population.

scholarly journals Evaluation of the Immune Response of a Candidate Phage-Based Vaccine against Rhipicephalus microplus (Cattle Tick)

Pharmaceutics ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 2018
Author(s):  
Alejandro González-Mora ◽  
Kenny Misael Calvillo-Rodríguez ◽  
Jesús Hernández-Pérez ◽  
Marco Rito-Palomares ◽  
Ana Carolina Martínez-Torres ◽  
...  
Keyword(s):  
Control Method ◽  
Ex Vivo ◽  
Rhipicephalus Microplus ◽  
Economic Losses ◽  
Cattle Tick ◽  
Severe Problem ◽  
Promising Alternative ◽  
In Vivo Assay ◽  
Cattle Ticks

Cattle tick (Rhipicephalus microplus) represents a severe problem causing substantial economic losses, estimated in billions of dollars annually. Currently, chemical acaricides represent the most widely used control method. However, several problems such as resistance have been described. Phage-based vaccines represent a fast and low-cost tool for antigen delivery. In this regard, the objective of the present work was to develop a candidate phage-based vaccine displaying a cattle tick antigen (Bm86-derived Sbm7462 antigen) on the surface of bacteriophage M13. Phage ELISA and dot blotting analysis confirmed the display of the antigen. Vaccine immunogenicity was evaluated using a bovine monocyte-derived dendritic cell-based ex vivo assay and a murine in vivo assay. The ex vivo model showed the maturation of dendritic cells after being pulsed with the phage-based vaccine. The humoral response was confirmed in the in vivo assay. These results demonstrated the capacity of the phage-based vaccine to induce both humoral and cellular immune-specific responses. Importantly, this is the first report describing a control method for cattle ticks using a candidate phage-based vaccine. Further studies to evaluate the immunogenicity in a bovine model are needed. The current approach represents a promising alternative to control cattle tick infestations.

scholarly journals Distribution of the cattle ticks from mid hills to plains of Nepal

2018 ◽  
Vol 1 (1) ◽  
pp. 197-205
Author(s):  
Bigya Dhital ◽  
Sulav Shrestha ◽  
Krishna Kaphle ◽  
Rameshwor Pudasaini
Keyword(s):  
Animal Husbandry ◽  
Body Part ◽  
Vascular Supply ◽  
Economic Losses ◽  
Tick Population ◽  
Body Parts ◽  
Cattle Ticks ◽  
Geographical Regions ◽  
Thin Skin ◽  
Study Sites

Ticks cause serious economic losses in livestock production worldwide. A study was conducted in 2017/18 to determine the abundance of tick population on different geographical regions and body parts of cattle. Three study sites were taken from mid hill, inner terai and terai region of Nepal. A total of 45 dairy cattle (15 from each region) were included randomly for the study. Regarding the distribution of ticks in cattle body part, higher number of ticks were recorded on dewlap (38.61%) followed by perineum and udder (25.10%), ear base (15.06%), tail base (9.07%), abdomen (7.34%) and withers (4.83%). Similarly, highest numbers of ticks were recorded in Chitwan (19.46 ticks on an average) cattle followed by Dang (9.13 ticks on an average) and least in Lamjung (5.73 ticks on an average) cattle. This result indicates that higher tick infestation was found in warm, moist, hidden sites with good vascular supply and thin skin in cattle body. Similarly, more tick were recorded in cattle keeping with poor animal husbandry practices.

scholarly journals Analysis of Bm86 conserved epitopes: is a global vaccine against Cattle Tick Rhipicephalus microplus possible?

2018 ◽  
Author(s):  
Isabella Maiumi Zaidan Blecha ◽  
Bárbara Guimarães Csordas ◽  
André de Abreu Rangel Aguirre ◽  
Rodrigo Casquero Cunha ◽  
Marcos Valério Garcia ◽  
...  
Keyword(s):  
Control Method ◽  
Phylogenetic Analyses ◽  
Rhipicephalus Microplus ◽  
Economic Losses ◽  
Antigenic Determinants ◽  
Cattle Tick ◽  
Universal Vaccine ◽  
Cattle Ticks ◽  
Geographical Regions ◽  
Different Populations

Abstract The cattle tick Rhipicephalus microplus causes significant economic losses in agribusiness. Control of this tick is achieved mainly through the application of chemical acaricides, often resulting in contamination of animal food products and of the environment. Another major concern associated with acaricide use is the increasing reports of resistance of this tick vector against the active ingredients of many commercial products. An alternative control method is vaccination. However, the commercially available vaccine based on a protein homologous to Bm86 exhibits variations in efficacy relative to the different geographical locations. This study aimed to identify antigenic determinants of the sequences of proteins homologous to Bm86. Phylogenetic analyses were performed to determine the extent of divergence between different populations of R. microplus to identify the sequence that could be used as a universal vaccine against the multiple geographically distinct populations of R. microplus and related tick species. Considering the extensive sequence and functional polymorphism observed among strains of R. microplus from different geographical regions, we can conclude that it may be possible to achieve effective vaccination against these cattle ticks using a single universal Bm86-based antigen.

“A Study on the Influence of Rewards on Job Satisfaction With Special Reference to Education Industry in Oman”

2019 ◽  
Vol 118 (1) ◽  
pp. 114-124
Author(s):  
Mrs Nithya Sambamoorthy ◽  
Mr Subhash Kodiyil Raman ◽  
Mr Bhraguram Thayyil
Keyword(s):  
Job Satisfaction ◽  
Special Reference ◽  
Secondary Data ◽  
The Other ◽  
Primary Data ◽  
Other Hand ◽  
Education Industry ◽  
College Of Technology ◽  
Main Factors ◽  
Structured Questionnaire

This research is an examination and a study on the influence of rewards on job satisfaction of lecturers at Shinas College of Technology (ShCT). In academic industry, rewards are one of the factors that affecting job satisfaction of the employees and this will lead to affect their performance in their jobs. So, when rewards are more the job satisfaction will be high and when rewards are less the job satisfaction will be less. On the other hand, the age will not affect the job satisfaction. Previous research reveals that Job satisfaction is very important to success the industry and the rewards are the main factors which affect job satisfaction. The main purpose of this study is to know the influence of rewards in job satisfaction among the lecturers in ShCT. Moreover, this research attempts to identify how much rewards affect the job satisfaction in ShCT.  For this study used two types of data which are: primary data and secondary data. The sources of primary data is the response from lecturers at ShCT. It is collected through structured questionnaire and distributed such to 60 respondents. Secondary data, collected from internet, books, journals, articles etc.

Computer Viruses and Their Role in Accounting Information Systems

2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Ali Shirzad ◽  
Shaban Mohammadi ◽  
Hamedesmaeili Oghaz
Keyword(s):  
Information Systems ◽  
Accounting Information ◽  
Financial Information ◽  
The Other ◽  
Accounting Information Systems ◽  
Computer Viruses ◽  
Other Hand ◽  
Main Factors

Dependence on information and rapidly changing technology can be seen in many organizations, with proper security and intelligence systems to protect themselves. But success in providing security depends on the awareness of managers and employees. The accounting information systems in organizations are the most important element. One of the factors threatening their system is virus. Malware are computer viruses that can cause a variety of disorders, including loss of data and accounting information systems are impaired in such case. On the other hand, one of the main objectives of the viruses is to steal financial information. In this paper, one of the main factors threatening the security of accounting information systems, the viruses are described.

The Parallel Mechanism and Variable Acceleration Control Method

2013 ◽  
Vol 579-580 ◽  
pp. 659-664
Author(s):  
Xiang Bo Ouyang ◽  
Ke Tian Li ◽  
Hong Jian Xia ◽  
Su Juan Wang ◽  
Huan Wei Zhou ◽  
...  
Keyword(s):  
Parallel Mechanism ◽  
Control Method ◽  
The Other ◽  
Connecting Rod ◽  
Motion Platform ◽  
The Third ◽  
Symmetric Structure ◽  
Slide Block ◽  
Operation Process ◽  
Moving Platform

t presents the parallel mechanism and variable acceleration control method, which is composed of slider, connecting rod, moving platform and linear guide etc. The motion platform is supported by three connecting rods through hinging, the other end of the connecting rods are respectively hinged with two sliders. Among them two pairs of connecting rod, two sliders and the moving platform formed a symmetric structure that is the so called Parallel Mechanism. The third connecting rod is parallel to one of two connecting rods, so that the two parallel connecting rods, slide block and the moving platform formed a parallelogram structure, it makes that the moving platform is always parallel to liner guiderail in the process of movement. By controlling the two sliders moving in the way of variable acceleration, it can make the trajectory curve, speed curve and acceleration curve of the moving platform are continuous, smooth, so impact and vibration of the moving platform is limited in the operation process.

scholarly journals In vitro activity of the hydroalcoholic extract of Chenopodium ambrosioides against engorged females of Rhipicephalus (Boophilus) microplus

2018 ◽  
Vol 84 (0) ◽  
Author(s):  
Eduardo Oliveira ◽  
Manoela da Silva ◽  
Lew Sprenger ◽  
Daniela Pedrassani
Keyword(s):  
High Efficiency ◽  
Boophilus Microplus ◽  
Vitro Activity ◽  
Economic Losses ◽  
Cattle Tick ◽  
Distilled Water ◽  
In Vitro Activity ◽  
Chenopodium Ambrosioides ◽  
Cattle Ticks

ABSTRACT: Rhipicephalus (Boophilus) microplus, known as the cattle tick, is a cause of great economic losses for dairy cattle farming because of its high frequency of occurrence and the difficulty in controlling it. The aim of this study was to evaluate the in vitro activity of Chenopodium ambrosioides extract on R. (B.) microplus. For this purpose, 125 females were selected and classified into five groups according to their weight, in order to ensure that the females used presented homogeneous weight. The treatments comprised 40 and 60% extracts of Chenopodium ambrosioides, distilled water, ethanol (70ºGL) and 12.5% amitraz. The extracts of C. ambrosioides (40 and 60%) showed effectiveness of 99.7 and 100% and higher percentages of dead females than the other treatments: 64 and 96%, respectively (p<0.001). In the groups exposed to distilled water and ethanol (70º GL), 92 and 88% of the females maintained oviposition. In the females exposed to 40 and 60% extracts, oviposition of 36 and 4% occurred, respectively. It was concluded that the extract of Chenopodium ambrosioides, at both concentration evaluated, had high efficiency against engorged females of cattle ticks.

Vegetation of temporary ponds in cold holes in the Taurus mountain chain (Turkey)

Biologia ◽  
2010 ◽  
Vol 65 (4) ◽  
Author(s):  
Ali Kavgaci ◽  
Andraž Čarni ◽  
Saime Başaran ◽  
Mehmet Ali Başaran ◽  
Petra Košir ◽  
...  
Keyword(s):  
Intermediate Zone ◽  
The Other ◽  
Temporary Ponds ◽  
Marsh Vegetation ◽  
Vegetation Zonation ◽  
Stellarietea Mediae ◽  
Main Factors ◽  
Grassland Communities ◽  
Mountain Chain ◽  
New Syntaxa

AbstractThe work deals with vegetation zonation in temporary ponds within cold holes in the Western Taurus mountain chain. There are two main factors that cause differentiation within the studied vegetation: one relates to the microtopography, the other to altitude. In the bottom of temporary ponds, marsh vegetation of Ranunculo argyrei-Tanacetea argentei (Sedo nani-Convolvuletalia galactici) appears (an endemic class vicariant to Scheuchzerio-Caricetea fuscae); in the intermediate zone, the vegetation is dominated by therophytes of Stellarietea mediae (Thero-Brometalia) and in the upper part, there is vegetation of hygrophilous grassland communities of Molinio-Arrhenatheretea (Potentillo-Polygonetalia). This zonation of communities can be found at lower altitudes (up to 1600 m); whereas at higher altitudes, the intermediate zone dominated by therophytes gradually disappears and then also the hygrophilous grasslands. The work also provides a description of new syntaxa, to wit: Ranunculo argyrei-Tanacetea argentei, Sedo nani-Convolvuletalia galactici, Rorippo aureae-Eleocharidion quinqueflorae, Sedo nani-Ranunculetum argyrei, Trifolio caudati-Hordeion geniculati, Taeniathero caput-medusae-Hordeetum geniculati, Alopecuro vaginati-Trifolion resupinati and Ornithogalo lanceolati-Elymetum repentis.

scholarly journals Microbiological analysis and sensitivity profile of Staphylococcus spp. in subclinical mastitis of dairy goats

2016 ◽  
Vol 68 (2) ◽  
pp. 336-344
Author(s):  
S.R.S. Salaberry ◽  
A.B.S. Saidenberg ◽  
E. Zuniga ◽  
F.F. Gonsales ◽  
P.A. Melville ◽  
...  
Keyword(s):  
Subclinical Mastitis ◽  
Economic Losses ◽  
Microbiological Analysis ◽  
Dairy Goats ◽  
Milk Samples ◽  
California Mastitis Test ◽  
Resistant Strains ◽  
Staphylococcus Spp ◽  
Sensitivity Profile

Subclinical mastitis in goats causes economic losses and risks to public health. Given the need for research that shows the most isolated staphylococci species and sensibility tests comparing the resistance between coagulase-negative (CNS) and positive Staphylococcus (CPS) goats with subclinical mastitis, the aim of this study was to identify the microorganisms isolated from milk samples of goats with subclinical mastitis, as well as define the staphylococci species and determine the sensitivity profile of Staphylococcus spp. to antimicrobials. To collect samples, tests were performed for mug of black background and California mastitis test (CMT), collecting milk from CMT positive animals. A total of 226 samples from seven herds of dairy goats was collected and forwarded to the laboratory, where they were seeded for the isolation of the microorganism and implementing the antibiotic sensibility test. Of these, 122 samples had bacterial growth and the most isolated staphylococci species were: S. epidermidis (24.55%), S. lugdunensis (15.40%) and S. intermedius (13.64%). Samples showed increased resistance to antimicrobials: penicillin (81.8%), oxacillin (60.0%) and ampicillin (55.5%). Greater sensitivity to: enrofloxacin (99.1%), erythromycin (98.2%), gentamicin (98.2%) and vancomycin (98.2%) were observed. The S. epidermidis showed higher antimicrobial resistance to amoxicillin and penicillin than S. lugdunensis and S. intermedius. Similar resistance in vitro between CNS and CPS was observed to most antimicrobials. It is important to control the overuse of antibiotics to prevent the emergence of resistant strains.

scholarly journals Erythroderma caused by vancomycin in children: concentration and speed of infusion

2013 ◽  
Vol 1 (2) ◽  
Author(s):  
José F. Luna Álvarez ◽  
Mónica Gómez Vázquez ◽  
Ana L. Moreno González ◽  
Aldo Melchor Hernández ◽  
Marco A. Escamilla-Acosta ◽  
...  
Keyword(s):  
Adverse Reaction ◽  
Clinical Practice ◽  
Retrospective Study ◽  
Clinical Characteristics ◽  
Male Gender ◽  
The Other ◽  
Paediatric Hospital ◽  
Other Hand ◽  
Red Man Syndrome ◽  
Main Factors

Vancomycin is an antibiotic glycopeptide that was isolated of the Streptomyces orientalis. It was introduced in the clinical practice for treatment of infections caused by staphylococcus in which other antibiotics were proving to be ineffective. In this retrospective study, we determine its prescription, clinical characteristics as well as the factors that favor the apparition of the erythroderma or red-man syndrome in a paediatric hospital. Forty patients to which physicians administer vancomycin and presented erythroderma were evaluated. Male gender was more predominated, with a total of 25 cases (62.5 %). The average age was of 12 ± 6 years. We identified two main factors that are directly related to the appearance of erythroderma. On one hand, the "concentration of the drug", which is related to the dilution that it is realized when a dose of vancomycin is going to be administered to the patient and on the other hand the “time or speed of infusion”. In the present study, it was found a low incident of this adverse reaction and few cases of complications.

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