scholarly journals Erythroderma caused by vancomycin in children: concentration and speed of infusion

2013 ◽  
Vol 1 (2) ◽  
Author(s):  
José F. Luna Álvarez ◽  
Mónica Gómez Vázquez ◽  
Ana L. Moreno González ◽  
Aldo Melchor Hernández ◽  
Marco A. Escamilla-Acosta ◽  
...  
Keyword(s):  
Adverse Reaction ◽  
Clinical Practice ◽  
Retrospective Study ◽  
Clinical Characteristics ◽  
Male Gender ◽  
The Other ◽  
Paediatric Hospital ◽  
Other Hand ◽  
Red Man Syndrome ◽  
Main Factors

Vancomycin is an antibiotic glycopeptide that was isolated of the Streptomyces orientalis. It was introduced in the clinical practice for treatment of infections caused by staphylococcus in which other antibiotics were proving to be ineffective. In this retrospective study, we determine its prescription, clinical characteristics as well as the factors that favor the apparition of the erythroderma or red-man syndrome in a paediatric hospital. Forty patients to which physicians administer vancomycin and presented erythroderma were evaluated. Male gender was more predominated, with a total of 25 cases (62.5 %). The average age was of 12 ± 6 years. We identified two main factors that are directly related to the appearance of erythroderma. On one hand, the "concentration of the drug", which is related to the dilution that it is realized when a dose of vancomycin is going to be administered to the patient and on the other hand the “time or speed of infusion”. In the present study, it was found a low incident of this adverse reaction and few cases of complications.

Radioimmunszintigraphie mit SPECT: Methodik, Probleme und klinische Erfahrungen

1987 ◽  
Vol 26 (05) ◽  
pp. 202-205 ◽  
Author(s):  
J. Fass ◽  
S. Truong ◽  
U. Büll ◽  
V. Schumpelick ◽  
R. Bares
Keyword(s):  
Clinical Practice ◽  
The Other ◽  
Whole Body ◽  
Blood Clearance ◽  
Planar Scintigraphy ◽  
Gastrointestinal Carcinomas ◽  
Body Regions ◽  
Other Hand ◽  
Body Retention ◽  
Klinische Erfahrungen

Radioimmunoscintigraphy (RIS) with 111ln- and 131 I-labelled monoclonal anti bodies (MAbs) against CEA and/or CA 19-9 was performed in 83 patients with various gastrointestinal carcinomas. A total of 276 body regions could be examined. The results of planar scintigraphy and SPECT were compared intraindividually. Using 111 In-labelled MAbs the sensitivity of RIS was significantly improved by SPECT (88.9 vs. 52.4% with planar scintigraphy, p <0.01). For131 l-labelled MAbs the effect was smaller (83.9 vs. 65.6% with planar scintigraphy, n.s.). This finding can be explained by different kinetics and biodistribution of the used MAb preparations.111 In-labelled MAbs with long whole-body retention and rapid blood clearance reveal ideal qualities for SPECT; on the other hand, the short whole-body retention of131 l-labelled MAbs leads to small count rates and therefore long counting times that make delayed SPECT unsuitable in clinical practice

“A Study on the Influence of Rewards on Job Satisfaction With Special Reference to Education Industry in Oman”

2019 ◽  
Vol 118 (1) ◽  
pp. 114-124
Author(s):  
Mrs Nithya Sambamoorthy ◽  
Mr Subhash Kodiyil Raman ◽  
Mr Bhraguram Thayyil
Keyword(s):  
Job Satisfaction ◽  
Special Reference ◽  
Secondary Data ◽  
The Other ◽  
Primary Data ◽  
Other Hand ◽  
Education Industry ◽  
College Of Technology ◽  
Main Factors ◽  
Structured Questionnaire

This research is an examination and a study on the influence of rewards on job satisfaction of lecturers at Shinas College of Technology (ShCT). In academic industry, rewards are one of the factors that affecting job satisfaction of the employees and this will lead to affect their performance in their jobs. So, when rewards are more the job satisfaction will be high and when rewards are less the job satisfaction will be less. On the other hand, the age will not affect the job satisfaction. Previous research reveals that Job satisfaction is very important to success the industry and the rewards are the main factors which affect job satisfaction. The main purpose of this study is to know the influence of rewards in job satisfaction among the lecturers in ShCT. Moreover, this research attempts to identify how much rewards affect the job satisfaction in ShCT.  For this study used two types of data which are: primary data and secondary data. The sources of primary data is the response from lecturers at ShCT. It is collected through structured questionnaire and distributed such to 60 respondents. Secondary data, collected from internet, books, journals, articles etc.

Computer Viruses and Their Role in Accounting Information Systems

2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Ali Shirzad ◽  
Shaban Mohammadi ◽  
Hamedesmaeili Oghaz
Keyword(s):  
Information Systems ◽  
Accounting Information ◽  
Financial Information ◽  
The Other ◽  
Accounting Information Systems ◽  
Computer Viruses ◽  
Other Hand ◽  
Main Factors

Dependence on information and rapidly changing technology can be seen in many organizations, with proper security and intelligence systems to protect themselves. But success in providing security depends on the awareness of managers and employees. The accounting information systems in organizations are the most important element. One of the factors threatening their system is virus. Malware are computer viruses that can cause a variety of disorders, including loss of data and accounting information systems are impaired in such case. On the other hand, one of the main objectives of the viruses is to steal financial information. In this paper, one of the main factors threatening the security of accounting information systems, the viruses are described.

scholarly journals Education and Social Reproduction in Schools

2015 ◽  
Vol 5 (1) ◽  
pp. 223
Author(s):  
Ibrahim Kurt
Keyword(s):  
Social Reproduction ◽  
The Other ◽  
Social Perspectives ◽  
Individual Function ◽  
Other Hand ◽  
The Social ◽  
Main Factors ◽  
Education Needs ◽  
The Individual

Education is important for all structures of the society. The structures of the society mainly classes are involved and tried to be educated in places which are separated deliberately for the aims. On the other hand, from society to society the aims and also the expectation can be changed. This article tries to explain and discuss the progressing of education as a perception for individual and society. The references will be found out according to the graduates those are the products of schools in the society and the education as a system for the classes in the structure of the society. As an instrument education needs to be given thought to on and reconsidered for the individual and social perspectives. Education is one of the main factors for the social reproduction in the society. That is a nature of the societies that they want to reproduce themselves as they are. So society cannot be separated from reproduction and education. Hence, in this paper, effort was made to establish the fact that education and social reproduction are the basic tools for cultural and individual function for the society. The paper asserts that education supports and helps social reproduction as one of the factors of socialization. For many years, in this way, education has done its duty in the society as a tool with its all stages formally or informally. The paper posits that social reproduction always goes on with its tools in the society. However it can be underline that education as a tool is changed and perception on education is considered in different ways for cultural and individual functions.

scholarly journals Standing Against to Workplace Discrimination (In the Name of Law & Order, Humanity, Religion, and Better Management): A Literature Review

2021 ◽  
Vol 04 (12) ◽  
Author(s):  
Cengiz Yılmaz ◽  
Keyword(s):  
Literature Review ◽  
Business Owners ◽  
Workplace Discrimination ◽  
The Other ◽  
Linguistic Variables ◽  
Managerial Efficiency ◽  
Efficient Management ◽  
Other Hand ◽  
Main Factors ◽  
The Law

Rational judgments and decisions should be based on solid logic and rationale as well as numeric variables. On the other hand, irrational judgments and decisions rely on feelings, linguistic variables. Appointed executives who manage acting businesses must demonstrate solid logic, numeric and linguistic justifications for their decisions to the stakeholders: business owners, government, share-stakeholders. The study examines the justification and logic of the four main factors why humanity fights against discrimination during the promotion: legally, humanitarian reasons, religious grounds, and administrative reasons. The study strongly suggests that discrimination during the promotion is against the law, religion, humanity, and efficient management. For these reasons, honest, fair people and organizations have to fight against discrimination; in the name of law, in the name of religion, in the name of humanity, and in the name of managerial efficiency. Discriminators, who are unfairly making the lives of innocent employees, their children, and partners hell, have to be punished by the law, religion, humanity, and management for realizing humanistic and holistic justice.

Pre- and post-conditioning of the heart: an overview of cardioprotective signaling pathways

2020 ◽  
Vol 19 ◽  
Author(s):  
Denise Coutinho de Miranda ◽  
Gabriela de Oliveira Faria ◽  
Milla Marques Hermidorff ◽  
Fernanda Cacilda dos Santos Silva ◽  
Leonardo Vinícius Monteiro de Assis ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Signaling Pathways ◽  
Exponential Growth ◽  
Comprehensive Evaluation ◽  
Therapeutic Agents ◽  
The Other ◽  
Other Hand ◽  
The Future

: Since the discovery of ischemic pre- and post-conditioning, more than 30 years ago, the knowledge about the mechanisms and signaling pathways involved in these processes has significantly increased. In clinical practice, on the other hand, such advancement has yet to be seen. This article provides an overview of ischemic pre-, post-, remote, and pharmacological conditioning related to the heart. In addition, we reviewed the cardioprotective signaling pathways and therapeutic agents involved in the above-mentioned processes, aiming to provide a comprehensive evaluation of the advancements in the field. The advancements made over the last decades cannot be ignored and with the exponential growth in techniques and applications. The future of pre- and post-conditioning is promising.

scholarly journals The Cost-Effective Laboratory: Implementation of Economic Evaluation of Laboratory Testing

2017 ◽  
Vol 36 (3) ◽  
pp. 238-242
Author(s):  
Natasa Bogavac-Stanojevic ◽  
Zorana Jelic-Ivanovic
Keyword(s):  
Clinical Practice ◽  
Laboratory Test ◽  
Laboratory Testing ◽  
Laboratory Tests ◽  
Clinical Decision Making ◽  
Economic Value ◽  
Cost Effective ◽  
The Other ◽  
Total Hospital Cost ◽  
Other Hand

SummaryLaboratory testing as a part of laboratoryin vitrodiagnostic (IVD) has become required tool in clinical practice for diagnosing, monitoring and prognosis of diseases, as well as for prediction of treatment response. The number of IVD tests available in laboratory practice has increased over the past decades and is likely to further increase in the future. Consequently, there is growing concern about the overutilization of laboratory tests and rising costs for laboratory testing. It is estimated that IVD accounts for between 1.4 and 2.3% of total healthcare expenditure and less than 5% of total hospital cost (Lewin Group report). These costs are rather low when compared to pharmaceuticals and medical aids which account for 15 and 5%, respectively. On the other hand, IVD tests play an important role in clinical practice, as they influence from 60% to 70% of clinical decision-making. Unfortunately, constant increases in healthcare spending are not directly related to healthcare benefit. Since healthcare resources are limited, health payers are interested whether the benefits of IVD tests are actually worth their cost. Many articles have introduced frameworks to assess the economic value of IVD tests. The most appropriate tool for quantitative assessment of their economic value is cost-effectiveness (CEA) and cost-utility (CUA) analysis. The both analysis determine cost in terms of effectiveness or utilities (combine quantity and quality of life) of new laboratory test against its alternative. On the other hand, some investigators recommended calculation of laboratory test value as product of two ratios: Laboratory test value = (Technical accuracy/Turnaround time) × (Utility/Costs). Recently, some researches used multicriteria decision analysis which allows comparison of diagnostic strategies in terms of benefits, opportunities, costs and risks. All analyses are constructed to identify laboratory test that produce the greatest healthcare benefit with the resources available. Without solid evidence that certain laboratory tests are cost-effective, laboratory services cannot be improved. Consequently, simple policy measures such as cost cutting may be imposed upon many laboratories while patients will have limited access to laboratory service.

scholarly journals HONOLULU

2003 ◽  
Author(s):  
Kirsten Møllegaard
Keyword(s):  
The Other ◽  
Edward Said ◽  
Grand Narrative ◽  
Tourist Gaze ◽  
The Past ◽  
Other Hand ◽  
Main Factors

In the grand narrative of Honolulu as the gateway to the Land of Aloha, Honolulu metaphorically negotiates a position that mediates the contrasts between a typical socio-economic, urban reality and touristic myths of pastoral excoticism. Drawing on the critical works of postcolonial scholar Edward Said in conjunction with theories on semiotics and tourism, the article posits that two main factors contribute to reinforce and repeat the (neo)-colonial paradigm’s persistence in the grand narrative on Hawaii – namely aloha and nostalgia. Aloha functions conceptually as a unifying, pacifying force amongst the local population, while it defines the tourist gaze on Hawaii as a welcoming and politically uncomplicated holiday destination. Nostalgia, on the other hand, is the ideological interpretation of the past based on utopian desires in the present. Conjoined, aloha and nostalgia favor the tourist gaze and continue the hegemonic processes that colonize the minds of tourists and locals alike.  

scholarly journals A Retrospective Study of 657 Women With Vaginal Intraepithelial Neoplasia (VaIN)

2021 ◽  
Author(s):  
Fanhui Meng ◽  
Yunyun Cao ◽  
Yudong Wang
Keyword(s):  
Retrospective Study ◽  
Clinical Characteristics ◽  
Intraepithelial Neoplasia ◽  
Diagnostic Methods ◽  
The Other ◽  
International Peace ◽  
Hpv Dna ◽  
Vaginal Intraepithelial Neoplasia ◽  
And Child Health ◽  
Health Hospital

Abstract Objective: The aim of this study was to explore the clinical characteristics of patients with VaIN and identify more sensitive diagnostic methods.Methods: This study retrospectively analyzed 657 patients with VaIN from the International Peace Maternal and Child Health Hospital in Shanghai during a ten-year period. Results: Among the 657 patients, 26.5% were diagnosed with VaIN 2/3. The proportions of patients with VaIN 2/3 among those who did and did not undergo hysterectomy were 39.5% and 24.7%, respectively. The sensitivity of cytology for VaIN in those with only VaIN, VaIN concomitant with cervical or vulvar lesions, and posthysterectomy VaIN was 56.7%, 66.5%, and 72.3%, respectively. The sensitivity of hrHPV for VaIN in the same categories was 87.7%, 86.5%, and 74.3%, respectively. The sensitivity of cytology and hrHPV cotesting for VaIN in the same categories was 95.2%, 95.6%, and 95.0%, respectively. In patients who did not undergo hysterectomy, HPV16 was detected in 9.5% of VaIN 1 lesions among the HPV DNA-positive patients, while the other 12 types of HPV were detected in 62.6% of VaIN 1 lesions. In patients who underwent hysterectomy, HPV16 was detected in 2.1% of VaIN 1 lesions, and the other 12 types of HPV were detected in 54.2% of VaIN 1 lesions.Conclusions: A combination of cytology and colposcopy could increase the sensitivity of the diagnosis of VaIN. The other 12 high-risk types of HPV positive may be more closely related to VAIN 1, more attention should be paid.

scholarly journals Higher levels of salivary α-amylase predict failure of cessation efforts in male smokers

2010 ◽  
pp. 765-771 ◽  
Author(s):  
M Dušková ◽  
K Šimůnková ◽  
M Hill ◽  
H Hruškovičová ◽  
P Hoskovcová ◽  
...  
Keyword(s):  
Gender Differences ◽  
Smoking Cessation ◽  
Clinical Practice ◽  
Stress Response ◽  
Salivary Cortisol ◽  
The Other ◽  
Active Smoking ◽  
Other Hand ◽  
Study Support ◽  
Cortisol Levels

The ability to predict the success or failure of smoking cessation efforts will be useful for clinical practice. Stress response is regulated by two primary neuroendocrine systems. Salivary cortisol has been used as a marker for the hypothalamuspituitary-adrenocortical axis and salivary α-amylase as a marker for the sympathetic adrenomedullary system. We studied 62 chronic smokers (34 women and 28 men with an average age of 45.2±12.9 years). The levels of salivary cortisol and salivary α-amylase were measured during the period of active smoking, and 6 weeks and 24 weeks after quitting. We analyzed the men separately from the women. The men who were unsuccessful in cessation showed significantly higher levels of salivary α-amylase over the entire course of the cessation attempt. Before stopping smoking, salivary cortisol levels were higher among the men who were unsuccessful in smoking cessation. After quitting, there were no differences between this group and the men who were successful in cessation. In women we found no differences between groups of successful and unsuccessful ex-smokers during cessation. In conclusions, increased levels of salivary αamylase before and during smoking cessation may predict failure to quit in men. On the other hand, no advantage was found in predicting the failure to quit in women. The results of our study support previously described gender differences in smoking cessation.

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