Three-Dimensional Facial Characteristics of Caucasian Infants without Cleft and Correlation with Body Measurements

2004 ◽  
Vol 41 (6) ◽  
pp. 593-602 ◽  
Author(s):  
Jill E. White ◽  
Ashraf F. Ayoub ◽  
Marie-Therese Hosey ◽  
Mitchum Bock ◽  
Adrian Bowman ◽  
...  

Objective The aim of this study was to characterize the soft tissue facial features of infants without cleft and to report on the correlation between these with weight, length, and head circumference. Design This was a prospective study using a noninvasive three-dimensional (3D) stereophotogrammetry (C3D) system to capture the images of the participants. Landmarks were identified on the 3D facial images. Means and SDs were derived for facial distances and angles. A facial asymmetry score was calculated for each image. Two sample Student's t tests, Pearson's correlation coefficients and analysis of covariance were used to ascertain any gender differences and determine whether these could be explained by weight differences. Participants Eighty-three infants, 41 boys and 42 girls, were captured at rest with their lips apart, at approximately 3 months of age. Results Significant sex differences, of 1 to 2 mm, were found in several facial dimensions, such as face height and nose width. The larger facial measurements correlated significantly with body measurements. Analysis of variance confirmed these differences could be explained by differences in weight. There were no sex differences in the nose/mouth width ratios or in any of the angles measured, suggesting that there may be little sex difference in shape. A slight degree of asymmetry in the faces of infants without cleft was detected. Conclusions Comparisons between noncleft controls and infants with cleft should take cognizance of normal age and sex variations in height and weight that occur among infants.

2019 ◽  
Vol 90 (3) ◽  
pp. 397-404 ◽  
Author(s):  
Zhuoxing Xiao ◽  
Zijin Liu ◽  
Yan Gu

ABSTRACT Objective To evaluate three-dimensional (3D) accuracy and reliability of nonradiographic dentofacial images integrated with a two-step method. Methods 3D facial images, cone-beam computed tomography (CBCT) images and digital maxillary dental casts were obtained from 20 pre-orthodontic subjects. Digital dental casts were integrated into 3D facial images using a two-step method based on the anterior tooth area. 3D coordinate values of five dental landmarks were identified in both dentofacial images and CBCT images. The accuracy of the integration method was assessed with paired t-tests between dentofacial images and CBCT-based reference standards. Intraclass correlation coefficients (ICCs) were assessed for the reliability of dentofacial images and CBCT-based images. Analysis of variance and Kruskal-Wallis tests evaluated the accuracy of the method in different dimensions. Results There was no statistical difference between dentofacial images and CBCT reference standards in both translational and rotational dimensions (P > .05). Translational mean absolute errors for full dentitions were within 0.42 mm and ICCs were over 0.998 in x, y, and z directions. Rotational mean absolute errors for full dentitions were within 0.92° and ICCs over 0.734 in pitch, yaw, and roll orientations. Integration errors were significantly greater in the first molar, z-translation, and pitch rotation (P < .05). Conclusions Integrating 3D dentofacial images with the two-step method is precise and acceptable for clinical diagnostics and scientific purposes. Errors were greater in the molar region, z-translation, and pitch rotation.


2007 ◽  
Vol 44 (4) ◽  
pp. 391-395 ◽  
Author(s):  
Mark F. Devlin ◽  
Arup Ray ◽  
Peter Raine ◽  
Adrian Bowman ◽  
Ashraf F. Ayoub

Objective: The aim of this study was to assess the outcome of bone grafting using a corticocancellous block of iliac crest to reconstruct the support for the deformed, volume-deficient alar base in treated patients with unilateral cleft lip and palate (UCLP). The main outcome being measured was nasal symmetry. Design: This was a prospective study using a noninvasive three-dimensional stereophotogrammetry system (C3D) to assess the position of the alar base. Images were captured immediately preoperatively and at 6 months following the augmentation of the alar base with a block of bone graft. These images were used to calculate facial symmetry scores and were compared using a two sample Student's t test to assess the efficacy of the surgical method in reducing facial/nasal asymmetry. Patients: This investigation was conducted on 18 patients with one patient failing to attend for follow-up. The results for 17 patients are presented. Results: Facial symmetry scores improved significantly following the insertion of the bone graft at the deficient alar base (p = 0.005). Conclusions: 3D stereophotogrammetry is a noninvasive, accurate, and archiveable method of assessing facial form and surgical change. Nasal symmetry can be quantified and measured reliably with this tool. Bone grafting to the alar base region of treated UCLP patients with volume deficiency produces improvement in nasal symmetry.


2012 ◽  
Vol 83 (2) ◽  
pp. 253-258 ◽  
Author(s):  
Jasmina Primozic ◽  
Giuseppe Perinetti ◽  
Stephen Richmond ◽  
Maja Ovsenik

ABSTRACT Objective: To assess the degree of facial asymmetry associated with subjects with unilateral functional crossbite (CB) in the primary, early/intermediate, and late mixed dentition phases in comparison with a group of subjects without CB. Subjects and Methods: A group of 234 white subjects, 78 with CB (42 girls and 36 boys) and 156 without CB (73 girls and 83 boys), aged 3.9–11.9, grouped according to the dentition phase, were included. Three-dimensional laser scans of the subjects' faces were used to assess facial asymmetry. For each part of the face two-way multivariate analysis of covariance was performed to assess differences among the subjects, and an independent sample t-test was used to assess the significance of the differences between data sets. Results: Within all dentition phases, the subjects with CB had statistically significantly greater facial asymmetry of the whole face than the subjects without CB, with the greatest values in the lower part of the face (P < .05). In the middle part of the face a significant difference was observed in the mixed dentition phases. Conclusions: Children with unilateral functional CB exhibited a greater facial asymmetry than children without this malocclusion in all the dentition phases herein investigated. The greatest differences were seen for the lower part of the face. Further, facial asymmetry in the middle part of the face became clinically relevant in combination with the transition from primary to mixed dentition phase.


2020 ◽  
Vol 12 (6) ◽  
pp. 1-10
Author(s):  
Patrick Danuor ◽  
Emmanuel Ampoma Affum

The spectral efficiency of three-dimensional (3D) massive MIMO is impaired due to the spatial correlation (SC) between closed-spaced elements of antenna arrays (AAs). This paper investigates the impacts of arbitrary Q-power variations of the Power Cosine distribution for a precise characterization of the SC. This is done by presenting mathematical expressions characterizing the SC of cylindrical antenna array (CAA) regarding Student's -t, Von Mises and Cosine distributions, for the direction of arrival (DoA) of the electromagnetic waves impinging on the receiving antenna. Unlike the Student's -t and Von Mises distribution, our outcome recorded huge mismatch between theoretical and simulation correlation coefficients for arbitrary Q-power values above ten (10) which also reduced the downlink channel capacity. The practical relevance is that even though higher Q-power values are the key parameters for system performance, meticulous selection of arbitrary Q-power values above ten (10) is essential to minimize errors regarding channel modelling.


2016 ◽  
Vol 27 (3) ◽  
pp. 76 ◽  
Author(s):  
B Olivier ◽  
AV Stewart ◽  
AC Green ◽  
W McKinon

Background. The cricket pace bowler utilises various strategies, including a more extended front knee angle, to achieve optimal performance benefits. At times this is done to the detriment of injury  prevention.Objective. To investigate the relationship between three-dimensional (3D) knee kinematics during pace bowling action, injury incidence and bowling performance at the start and end of a cricket season.Methods. Knee angle and ball release (BR) speed of injury-free premier league (club level) cricket pace bowlers over the age of 18 years were measured at the start and end of the cricket season. Kinematic, injury- and bowling performance-related (BR speed and accuracy) data were analysed using paired and independent Student's t-tests, Pearson's correlation coefficient,χ2 test and a two-way analysis of covariance with repeated measures.Results. Thirty-one bowlers participated in this study, and kinematic data of a subset of 17 were  analysed. Nine bowlers (53%) sustained injuries during the cricket season. No statistically significant relationship was found between knee angle and injury. Bowlers who did not sustain an injury bowled with more knee flexion at the start of the season (mean (standard deviation) 157.07° (12.02°)) than at the end of it (163.95° (6.97°)) (p=0.01). There was no interaction between accuracy and knee angle. There  was a good to excellent inverse correlation between BR speed and knee angle among bowlers who  remained injury free (r=.0.79; p=0.18).Conclusion. Bowlers who remain injury free during the course of the season may use strategies other than the front knee angle to facilitate high BR speeds. Technique-related variables which are more  'protective' against injuries while allowing for higher BR speeds should be further investigated among bowlers.


Author(s):  
I.M. Vorotnikov ◽  
V.A. Razin ◽  
I.M. Lamzin ◽  
M.N. Sokolova ◽  
M.E. Khapman ◽  
...  

Anemia is one of the most common complications of blood donation. Thus, the objective of the paper was to assess the risks of anemia development in donors according to the regularity of donation and inherited predisposition. Materials and Methods. The authors carried out a prospective study, which included 241 blood donors, using random sampling and case-control techniques. Depending on blood donation frequency, the donors were divided into 2 groups: Group 1 consisted of 122 people (51.5 %) frequently donating blood; Group 2 included 119 people (48. 5 %) rarely donating blood. We studied the initial indicators of a general blood test and the same indicators a year after the first blood donation. Additionally, we performed HLA typing of donors. Statistica v. 8.0 software package (Stat Soft Inc., USA) was used for statistical analysis. To compare two independent samples, we used a nonparametric Mann-Whitney U-test and a parametric Student’s t-test (depending on the type of distribution). To assess anemia risks, the odds ratio was calculated. Results. One year after the first blood donation, anemia was diagnosed in 13 people (10.6 %) in Group 1 and in 7 people (5.9 %) in Group 2 (p=0.179). A11 and B7 HLA antigens did not increase anemia risks in group 1 (OS=1.257 (95 % CI 0.318–4.973) and OS=0.240 (95 % CI 0.051–1.134, respectively). HLA-antigens A11 and B7 did not increase anemia risks in Group 1 (OR=1.257 (95 % CI 0.318-4.973) and OR=0.240 (95 % CI 0.051–1.134), respectively). In group 2, antigen-A11 was also an insignificant factor (OS=2.902 (95 % CI 0.606-13.889)) for anemia development. Whereas, antigen-B7 increased anemia risks by 14 times (OS=14.364 (95 % CI 1.644-124.011)). Conclusion. In rare blood donors, it is the genetic factor that plays the main role in anemia development. High prevalence rates of anemia in frequent blood donors are probably determined by other factors. Keywords: anemia, blood donors, HLA typing. Механизмы развития анемий и факторы, их индуцирующие, остаются до конца не изученными. Целью исследования стало изучение риска развития анемии у доноров крови в зависимости от частоты донации и наличия наследственной предрасположенности к развитию анемии. Материалы и методы. Проведено проспективное исследование, выполненное методами случайной выборки и «случай-контроль», в которое вошел 241 донор крови. В зависимости от частоты сдачи доноры были поделены на 2 группы: группу 1 составили 122 чел. (51,5 %), часто сдающие кровь; группу 2 – 119 чел. (48,5 %), редко сдающих кровь. Изучались исходные показатели общего анализа крови и через год от начала донации. Дополнительно проводилось HLA-типирование доноров. Статистический анализ осуществлялся с применением программы Statistica v. 8.0 (Stat Soft Inc., США). Для сравнения двух независимых выборок использовался непараметрический U-критерий Манна–Уитни и параметрический t-критерий Стьюдента (в зависимости от типа распределения). Для оценки риска возникновения анемии рассчитывалось отношение шансов. Результаты. Через год с момента первой сдачи крови в группе 1 выявлено 13 чел. (10,6 %) с анемией, в группе 2 – 7 чел. (5,9 %) (р=0,179). Наличие HLA-антигенов А11 и B7 не повышало риск развития анемии в группе 1 (ОШ=1,257 (95 % ДИ 0,318–4,973) и ОШ=0,240 (95 % ДИ 0,051–1,134 соответственно). В группе 2 наличие гена А11 также являлось незначимым фактором (ОШ=2,902 (95 % ДИ 0,606–13,889), присутствие гена В7 в 14 раз повышало риск развития анемии (ОШ=14,364 (95 % ДИ 1,664–124,011). Выводы. Высокий риск развития анемии у редко сдающих кровь доноров обусловливается генетическими факторами. Высокая распространённость анемии у часто сдающих кровь доноров, вероятно, определяется другими факторами. Ключевые слова: анемия, доноры крови, HLA-типирование.


2020 ◽  
Vol 13 (12) ◽  
pp. e239286
Author(s):  
Kumar Nilesh ◽  
Prashant Punde ◽  
Nitin Shivajirao Patil ◽  
Amol Gautam

Ossifying fibroma (OF) is a rare, benign, fibro-osseous lesion of the jawbone characterised by replacement of the normal bone with fibrous tissue. The fibrous tissue shows varying amount of calcified structures resembling bone and/or cementum. The central variant of OF is rare, and shows predilection for mandible among the jawbone. Although it is classified as fibro-osseous lesion, it clinically behaves as a benign tumour and can grow to large size, causing bony swelling and facial asymmetry. This paper reports a case of large central OF of mandible in a 40-year-old male patient. The lesion was treated by segmental resection of mandible. Reconstruction of the surgical defect was done using avascular fibula bone graft. Role of three-dimensional printing of jaw and its benefits in surgical planning and reconstruction are also highlighted.


1994 ◽  
Vol 14 (3) ◽  
pp. 236-239 ◽  
Author(s):  
Edward C. Kohaut ◽  
F. Bryson Waldo ◽  
Mark R. Benfield

Objectives To determine the effect of changing dialysate volume on urea and glucoseequilibration curves and to determine, if dialysate volume is prescribed on the basis of body surface area, whether equilibration curves will be consistent in patients of different sizes and ages. Design A prospective study wherein children with acute or chronic renal failure had peritoneal equilibration studies done with dwell volumes of 30 mL/kg, 40 mL/kg, and 1200 mL/m2. Patient Population Twenty-two children: 7 under 3 years of age; 8 between 3 and 10 years of age; 7 older than 10 years of age. Statistics Student's t-test. Results Urea and glucose equilibrated rapidly at dwell volumes of 30 mL/kg, slower at dwell volumes of 40 mL/kg, and slowest at dwell volumes of 1200 mL/m2. Equilibration curves were similar in children of different ages when dialysate volumes of 1200 mL/m2 were infused. Conclusion Dialysate volumes of 1200 mL/m2 should be used when equilibration studies are being done to compare individuals of different ages and sizes.


2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Zhe Li ◽  
Guanzhi Liu ◽  
Run Tian ◽  
Ning Kong ◽  
Yue Li ◽  
...  

Abstract Background Our objective was to obtain normal patellofemoral measurements to analyse sex and individual differences. In addition, the absolute values and indices of tibial tuberosity-trochlear groove (TT-TG) distances are still controversial in clinical application. A better method to enable precise prediction is still needed. Methods Seventy-eight knees of 78 participants without knee pathologies were included in this cross-sectional study. A CT scan was conducted for all participants and three-dimensional knee models were constructed using Mimics and SolidWorks software. We measured and analysed 19 parameters including the TT-TG distance and dimensions and shapes of the patella, femur, tibia, and trochlea. LASSO regression was used to predict the normal TT-TG distances. Results The dimensional parameters, TT-TG distance, and femoral aspect ratio of the men were significantly larger than those of women (all p values < 0.05). However, after controlling for the bias from age, height, and weight, there were no significant differences in TT-TG distances and anterior-posterior dimensions between the sexes (all p values > 0.05). The Pearson correlation coefficients between the anterior femoral offset and other indexes were consistently below 0.3, indicating no relationship or a weak relationship. Similar results were observed for the sulcus angle and the Wiberg index. Using LASSO regression, we obtained four parameters to predict the TT-TG distance (R2 = 0.5612, p < 0.01) to achieve the optimal accuracy and convenience. Conclusions Normative data of patellofemoral morphology were provided for the Chinese population. The anterior-posterior dimensions of the women were thicker than those of men for the same medial-lateral dimensions. More attention should be paid to not only sex differences but also individual differences, especially the anterior condyle and trochlea. In addition, this study provided a new method to predict TT-TG distances accurately.


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