Effects of injecting growth hormone or thyroxine on milk production and blood plasma concentrations of insulin-like growth factors I and II in dairy cows

1987 ◽  
Vol 114 (1) ◽  
pp. 17-24 ◽  
Author(s):  
S. R. Davis ◽  
P. D. Gluckman ◽  
I.C. Hart ◽  
H. V. Henderson
Keyword(s):  
Plasma Concentration ◽  
Milk Yield ◽  
Milk Protein ◽  
Plasma Concentrations ◽  
Experimental Period ◽  
Milk Composition ◽  
Saline Control ◽  
Milk Protein Content ◽  
Igf I ◽  
The Difference

ABSTRACT Three cows received injections of thyroxine (T4; 20 mg/day), four cows GH (40 mg/day) and three cows saline (control; 10 ml/day) on days 5–8 of a 16-day experimental period during peak lactation. Milk yield increased 13% in cows given GH (from 14·6 to 16·5 kg/day) and 15% in cows given T4 (from 15·8 to 18·2kg/day) but did not change in control cows. Injection of T4 increased milkfat and lactose content but reduced milk protein content. Injection of GH was without effect on milk composition during the injection period but milk protein rose after injections ceased. Injection of T4 increased plasma concentrations of T4 and tri-iodothyronine six- to sevenfold, with maxima occurring on day 9. Injection of GH increased the plasma concentration of GH five- to tenfold 5 h after injection. The plasma concentration of insulin-like growth factor I (IGF-I) was increased in cows given GH in both morning (08.30 h) and afternoon (14.30 h) blood samples, the difference being greatest in afternoon samples in which plasma IGF-I content increased from 3·3 to 6·8 nmol/l. Injection of T4 reduced the plasma concentration of IGF-I in morning samples but the concentration in afternoon samples remained relatively constant throughout the 16-day experimental period. The plasma concentration of IGF-II rose in morning samples in all treatment groups to reach a maximum of 200–250 nmol/l by day 9. The galactopoietic response to injection of GH but not T4 was associated with an increase in plasma concentration of IGF-I. Changes in plasma concentration of IGF-II were not associated with changes in milk yield. J. Endocr. (1987) 114, 17–24

scholarly journals Effect of Ruminally-protected leucine supplement on milk yield and plasma amino acids in dairy cows

2008 ◽  
Vol 17 (4) ◽  
pp. 351 ◽  
Author(s):  
L. KRÍZOVÁ ◽  
J. TRINÁCTÝ ◽  
M. RICHTER
Keyword(s):  
Amino Acids ◽  
Milk Yield ◽  
Dry Matter ◽  
Milk Protein ◽  
Experimental Period ◽  
Dry Matter Intake ◽  
Plasma Amino Acids ◽  
Maize Silage ◽  
Milk Protein Content ◽  
Ad Libitum

The aim of this study was to determine the influence of leucine supplement in the form of rumen-protected tablets on milk yield and composition and plasma amino acids in four high-yielding lactating Holstein cows. The experiment was carried out as a cross-over procedure and was divided into 4 periods of 14 d (10 d preliminary period and 4 d experimental period). Cows were fed ad libitum a diet based on maize silage, lucerne hay and a supplemental mixture. The diet, defficient in methionine, lysine, and leucine, was supplemented with methionine+lysine (Control) or methionine+lysine+leucine (Leu) in rumen protected form. The dry matter intake, milk yield and milk yield expressed in energy corrected milk did not differ significantly between the treatments. Milk protein content and yield did not show statistically significant variation. The contents and yield of casein, fat, lactose and urea were unaffected by the treatment. Blood metabolites did not vary between the treatments. The introduction of Leu resulted in higher plasma levels of proline (p

Comparison of the effects of administration of recombinant bovine growth hormone or N-Met insulin-like growth factor-I to lactating goats

1989 ◽  
Vol 123 (1) ◽  
pp. 33-39 ◽  
Author(s):  
S. R. Davis ◽  
P. D. Gluckman ◽  
S. C. Hodgkinson ◽  
V. C. Farr ◽  
B. H. Breier ◽  
...  
Keyword(s):  
Growth Factor ◽  
Milk Yield ◽  
Plasma Concentrations ◽  
Physiological Saline ◽  
Experimental Period ◽  
Yield Response ◽  
Insulin Like Growth Factor ◽  
Lactating Goats ◽  
Igf I ◽  
Sustained Increase

ABSTRACT Five goats were injected with GH (15 mg/day), three goats received systemic infusions of insulin-like growth factor (IGF)-I (43 nmol/h) and four goats received systemic infusions of physiological saline (20 ml/h) on days 4–6 of a 10-day experimental period during mid-lactation. Milk yield increased by an average of 24% in GH-treated goats by the time of the third injection. In contrast, milk yield of IGF-I-infused goats did not differ from saline-infused animals although two of three goats did show a small increase (12%) after 36 h of IGF-I infusion. With GH and IGF-I treatments plasma IGF-I concentrations increased similarly, reaching maxima of 100–130 nmol/l within 24 h. Plasma IGF-I concentration was relatively constant in saline-infused goats at about 50 nmol/l throughout the experiment. Total IGF-I bound to 50 kDa and 150 kDa binding proteins in plasma was increased by GH and IGF-I treatments but, in contrast to IGF-I, GH increased the proportion of IGF-I bound to 150 kDa binding protein. In a second experiment, four goats received systemic infusion of IGF-I (43 nmol/h) and four goats received systemic infusion of physiological saline (20 ml/h). There was no evidence that milk yield was changed during IGF-I infusion. However, when those goats which had previously received IGF-I infusions were injected with GH, milk yield increased by 30%. While the increment in plasma IGF-I concentration during IGF-I infusion was similar to that obtained in the first experiment, the IGF-I response to GH injection was much greater, plasma concentrations rising to 230 nmol/l. The data show a lack of milk yield response in goats whose plasma IGF-I concentrations were increased by IGF-I administration. Systemic infusion of IGF-I appears to be ineffective as a means of procuring a sustained increase in milk production. Journal of Endocrinology (1989) 123, 33–39

scholarly journals EFFECT OF FEEDING OAK (Quercus aegilops) ACORNS ON MILK PRODUCTION, MILK COMPOSITION AND SOME BLOOD BIOCHEMICAL PARAMETERS OF BLACK GOATS

2021 ◽  
Vol 52 (1) ◽  
pp. 28-35
Author(s):  
Hoger M. Hidayet ◽  
Kamal N. Mustafa
Keyword(s):  
Milk Yield ◽  
Milk Protein ◽  
Control Diet ◽  
Milk Composition ◽  
Serum Glucose ◽  
Blood Biochemical ◽  
Milk Protein Content ◽  
Serum Biochemical ◽  
Daily Milk Yield ◽  
Daily Milk

 Twenty four Black goat does at 1st week post kidding were adapted to control diet for 2 weeks and then blocked into 4 groups (6 does/group) to be fed on one of the experimental diets (0, 5, 10 and 15% oak acorns) to study the effect of different levels of oak acorns on milk yield, milk composition and some serum biochemical traits. Results revealed that at 10th week of lactation, there was a significant increase in daily milk yield in does fed on 15% oak acorns. In contrast the group fed on 15% oak acorns exhibited a significant decrease in milk protein and solid non-fat contents at 10th week of lactation. The milk lactose yield was significantly higher in group fed on 15% oak acorns at 10th week of lactation. The serum glucose concentration at 8th week of lactation was significantly higher in does fed on 10% oak acorns while at 10th week; it was significantly higher in does fed 5% oak acorns. It could be concluded that feeding does on diets containing 15% oak acorns caused a significant increase in daily milk yield of Black goats and a significant decrease in milk protein content.

scholarly journals Effects of rumen-protected methionine supplementation on the performance of high production dairy cows in the tropics

2020 ◽  
Author(s):  
Valdir Chiogna Junior ◽  
Fernanda Lopes ◽  
Charles George Schwab ◽  
Mateus Zucato Toledo ◽  
Edgar Alain Collao-Saenz
Keyword(s):  
Body Weight ◽  
Milk Yield ◽  
Milk Fat ◽  
Milk Protein ◽  
Body Condition Score ◽  
Block Design ◽  
Energy Levels ◽  
Basal Diet ◽  
Experimental Period ◽  
Milk Composition

AbstractIncreasing methionine availability in dairy cow diets during the first third of lactation may enhance their performance and health. The aim of this study was to determine the effect of supplementing rumen-protected methionine (RPMet) in a lactation diet containing adequate protein and energy levels. Seventy-six multiparous Holstein cows (39.1 ± 6.8 kg of milk/d and 65 ± 28 DIM) were assigned to 1 of 2 dietary treatments (38/treatment) according to a randomized complete block design with a 2-wk (covariate) and 10-wk experimental period. Treatments were a basal diet (CON; 3.77 Lys:1Met); and CON + 14 g RPMet (2.97 Lys:1 Met). Individual milk samples were taken every 2 weeks to determine milk composition. Blood was collected from 24 cows on d+30 d to measure plasma AA levels. Body weight and body condition score (BCS) were measured at the beginning and the end of the experiment. The SM diet promoted higher milk yield (41.7 vs. 40.1 kg/d; P = 0.026), energy-corrected milk yield (41.0 vs. 38.0 kg/d; P ≤ 0.01), milk protein yield (1.30 vs. 1.18 kg/d; P ≤ 0.01), and milk fat yield (1.42 vs. 1.29 kg/d; P = 0.02). Higher milk protein (3.14% vs. 2.97%; P ≤ 0.01) and casein (2.39% vs. 2.28%; P≤ 0.01) and a trend (P = 0.06) for higher milk fat % (3.41% vs. 3.21%) were also observed. Both diets resulted in similar body weight, but CON-fed cows tended (P = 0.08) to have higher BCS. Higher plasma methionine levels were determined with SM compared with CON (29.6 vs. 18.4 μM; P < 0.01), but lysine and histidine were not different. Dietary supplementation of RPM improved productive performance by increasing milk yield and milk components yields, suggesting better dietary AA utilization when Met levels are adjusted in Lys-adequate lactation diets.

scholarly journals Effects of rumen-protected methionine supplementation on the performance of high production dairy cows in the tropics

PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0243953
Author(s):  
Valdir Chiogna Junior ◽  
Fernanda Lopes ◽  
Charles George Schwab ◽  
Mateus Zucato Toledo ◽  
Edgar Alain Collao-Saenz
Keyword(s):  
Body Weight ◽  
Milk Yield ◽  
Milk Fat ◽  
Milk Protein ◽  
Body Condition Score ◽  
Block Design ◽  
Energy Levels ◽  
Basal Diet ◽  
Experimental Period ◽  
Milk Composition

Increasing methionine availability in dairy cow diets during the first third of lactation may enhance their performance and health. The aim of this study was to determine the effect of supplementing rumen-protected methionine (Smartamine® M, SM) in a lactation diet with protein and energy levels calculated according to the literature. Seventy-six multiparous Holstein cows (39.1 ± 6.8 kg of milk/d and 65 ± 28 DIM) were assigned to 1 of 2 dietary treatments (38/treatment) according to a randomized complete block design with a 2-wk (covariate) and 10-wk experimental period. Treatments were a basal diet (CON; 3.77 Lys:1Met); and CON + 23 g SM (2.97 Lys:1 Met). Individual milk samples were taken every 2 weeks to determine milk composition. Blood was collected from 24 cows on d+30 d to measure plasma AA levels. Body weight and body condition score (BCS) were measured at the beginning and the end of the experiment. The SM diet promoted higher milk yield (41.7 vs. 40.1 kg/d; P = 0.03). Energy-corrected milk yield (41.0 vs. 38.0 kg/d), milk protein yield (1.30 vs. 1.18 kg/d), milk protein (3.14% vs. 2.97%) and casein (2.39% vs. 2.28%) were also different (P < 0.01) as well as milk fat yield (1.42 vs. 1.29 kg/d; P = 0.02). A trend (P = 0.06) for higher milk fat % (3.41% vs. 3.21%) was observed. Both diets resulted in similar body weight, but CON-fed cows tended (P = 0.08) to have higher BCS. Higher plasma methionine levels were determined with SM compared with CON (29.6 vs. 18.4 μM; P < 0.01), but lysine and histidine were not different. Dietary supplementation of RPM improved productive performance by increasing milk yield and milk components yields, suggesting better dietary AA utilization when Met levels are adjusted in Lys-adequate lactation diets.

scholarly journals Milk fatty acid profile from grazing buffaloes fed a blend of soybean and linseed oils

2015 ◽  
Vol 67 (3) ◽  
pp. 927-934 ◽  
Author(s):  
G.A. Gagliostro ◽  
E.M. Patiño ◽  
M. Sanchez Negrette ◽  
G. Sager ◽  
L. Castelli ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Milk Fat ◽  
Nutritional Value ◽  
Milk Protein ◽  
Vaccenic Acid ◽  
Total Content ◽  
Experimental Period ◽  
Fat Content ◽  
Milk Fatty Acid ◽  
Milk Protein Content

The aim of the study was to examine the changes in milk fatty acid (FA) profile of grazing buffaloes fed either low (L, 276g/d) or high (H, 572g/d) doses of a blend (70:30, wt/wt) of soybean and linseed oils. Fourteen multiparous Mediterranean buffaloes grazing on a native pasture were fed 4 kg/day of a commercial concentrate containing no supplemental oil over a pre-experimental period of ten days. The baseline milk production and composition and milk FA profile were measured over the last three days. After this pre-experimental period the animals received the same concentrate added with either the L or H oil doses for 26 additional days. Milk yield (g/animal/day) did not differ at the start (1776 ± 522 and 1662 ± 291 for L and H, respectively, P<0.622) or at the end of the trial (4590 ± 991 and 4847 ± 447 in L and H, respectively, P<0.543). Baseline milk fat content (g/kg) averaged 77.1 (±20.5) in L and 74.3 (±9.9) in H (P<0.10) and was reduced (P<0.031) to 60.7 (±23.6) and 49.4 (±11.2) (P<0.0031) respectively after L and H with no differences between treatments (P<0.277). Baseline milk protein content (L=43.2 ± 3.4 and H= 44.3 ± 6.9g/kg) increased after oil supplementation (P<0.0001) in both L (73.2 ± 6.0g/kg) and H (68.4 ± 4.9g/kg) without differences between oil doses (P<0.123). Milk fat content of 14:0 decreased after oil supplementation only in the H treatment (5.29 to 4.03, P<0.007) whereas that of 16:0 was reduced (P<0.001) at both L (24.49 to 19.75g/100g FA) and H (25.92 to 19.17g/100g FA) doses. The reduction of total content of 12:0 to 16:0 was higher (P<0.052) in H (32.02 to 23.93g/100g FA) than L (30.17 to 25.45g/100g FA). Vaccenic acid content increased (P<0.001) from 5.70 to 13.24g/100g FA in L and from 5.25 to 16.77 in H, with higher results in the in H treatment (P<0.001). Baseline rumenic acid was sharply increased (P<0.001) in L (1.80 to 4.09g/100g FA, +127%) and H (1.60 to 4.61g/100g FA, +187%) with no differences between L and H (P<0.19). Overall, these results indicate a pronounced improvement in the nutritional value of milk fat from grazing buffaloes fed little amounts (0.276g/day) of a blend of soybean and linseed oils.

scholarly journals Effect of season, genotype and lactation on milk yield and composition of local and crossbred dairy cows reared under different feed base region

2016 ◽  
Vol 19 (1-2) ◽  
pp. 50-65
Author(s):  
MA Baset ◽  
KS Huque ◽  
NR Sarker ◽  
MM Hossain ◽  
MN Islam
Keyword(s):  
Milk Yield ◽  
Milk Fat ◽  
Milk Protein ◽  
Block Design ◽  
Milk Composition ◽  
Base Region ◽  
Total Solids ◽  
Randomized Block Design ◽  
Daily Milk Yield ◽  
Daily Milk

A total of 160 cows, 10 cows in each of native (local cow) and crossbred (local × Holstein Friesian) origins differing in lactation were used in 2×2×2×2 factorial experiment using Randomized Block Design (RBD) to evaluate milk yield and composition of cows considering regions (good & poor feed base region), seasons (dry: Nov.–Feb. 2009 & wet: Jun.–Oct. 2009), genotypes and lactation. A “good and/or poor feed base” region was classified based on the availability of quantity and quality roughages throughout the year. The study revealed that the daily milk yield and 4% FCM of cows under good feed base condition were 6.76 and 6.49 kg, respectively and under poor feed base condition were 3.67 and 3.31 kg, respectively. Feed base region did not affect on milk fat and it was observed that the milk protein, lactose, solids-not-fat (SNF), minerals and total solids under good feed base condition were 37.9, 54.9, 100.9, 6.3 and 140.6 g/kg, respectively, whereas, under poor feed base condition the values were 36.3, 52.9, 98.0, 6.1 and 135.2 g/kg, respectively. Season did not affect milk yield and composition except minerals (6.5 g/kg vs. 5.9 g/kg). Genotypes significantly (p?0.01) influenced daily milk yield, the milk protein and minerals. Lactation did not affect milk yield and the milk protein, but influenced the fat, lactose, SNF, minerals and total solids. The interaction of feed base regions and seasons significantly (p?0.01) influenced milk yield and the milk fat and SNF. The milk protein and lactose was influenced by the interaction of feed bases region, seasons and lactation. Milk yield negatively correlated with fat per cent. The percentage of fat significantly (p?0.01) correlated with protein, lactose, SNF, and minerals %. The percentage protein correlated with lactose, SNF and minerals. Lactose % significantly (p?0.01) correlated with SNF%. It may be concluded that milk yield and composition depends on feed base region, genotype and lactation of cows. Season did not influence milk yield and the composition. Milk yield negatively correlated with the percentage of fat, protein, lactose, SNF and milk composition strongly correlated with each other.Bangladesh J. of Livestock Res. 19(1-2): 50-65, Jan-Dec 2012

The effect of level and type of supplement offered to grazing dairy cows on herbage intake, animal performance and rumen fermentation characteristics

2003 ◽  
Vol 76 (3) ◽  
pp. 439-454 ◽  
Author(s):  
H. J. Sayers ◽  
C. S. Mayne ◽  
C. G. Bartram
Keyword(s):  
Dairy Cows ◽  
Milk Yield ◽  
Milk Protein ◽  
Protein Composition ◽  
Experimental Period ◽  
Yield Response ◽  
Animal Performance ◽  
Two Phase ◽  
Grazed Pasture ◽  
Herbage Intake

AbstractA study was undertaken to examine the effect of level and type of supplement and changes in the chemical composition of herbage through the grazing season on herbage intake, animal performance and rumen characteristics with high-yielding dairy cows. Thirty-two high genetic merit dairy cows were allocated to one of four treatments in a two-phase change-over design experiment. The four treatments involved offering either high-fibre (HF) or high-starch (HS) supplements at either 5 or 10 kg dry matter (DM) per day. Animals rotationally grazed perennial ryegrass swards offered a daily herbage allowance of 23 kg DM. High levels of animal performance were maintained throughout the study with mean milk yields over the 21-week experimental period of 35·5 and 37·2 kg per cow per day on the 5- and 10-kg treatments respectively. Supplement type had no significant effect on herbage intake. Increasing the level of supplementation reduced herbage intake by 0·49 and 0·46 kg herbage DM per kg supplement DM and increased milk yield, with a milk yield response of 0·55 and 0·65 kg/kg supplement DM offered in phases 1 and 2. Supplement type had no significant effect on milk yield and milk butterfat content. However, in both phases 1 and 2, milk protein content was significantly higher with cows offered the HS supplement compared with the HF supplement, this being particularly evident at the higher level of supplementation. Supplement type also had marked effects on milk protein composition. These results indicate that high levels of performance can be achieved with dairy cows on grazed pasture with moderate levels of supplementation.

scholarly journals The chemical composition and technological properties of milk obtained from the morning and evening milking

2008 ◽  
Vol 56 (5) ◽  
pp. 187-198 ◽  
Author(s):  
Martin Skýpala ◽  
Gustav Chládek
Keyword(s):  
Protein Content ◽  
Milk Yield ◽  
Milk Fat ◽  
Protein Production ◽  
Milk Protein ◽  
Fat Content ◽  
Total Solids ◽  
Milk Protein Content ◽  
Solids Content ◽  
Morning Milk

Milk yield varies during lactation, following what is termed a lactation curve. ŽIŽLAVSKÝ and MIKŠÍK (1988) recorded changes in milk yield within a day, too. TEPLÝ et al. (1979) a KOUŘIMSKÁ et al. (2007) published variation within a day ± 1.10 kg in milk yield, ± 0.75 % in milk fat content and ± 0.20 % in milk protein content. Milk yield of cows can be expressed in many different ways, for instance, in kilograms per lactation or in kilograms per day. A practical parameter describing milk production is milk yield (kg) per milking.The object of experiment were 12 cows of Holstein cattle on the first lactation from the 100-day of lactation to 200-day of lactation. The samples of milk were collected from January to May 2007, once a month from the morning and evening milking (milking interval 12 h ± 15 min.). The following parameters were monitored: milk production – milk yield (kg), milk protein production (kg), milk fat production (kg); milk composition – milk protein content (%), milk fat content (%), lactose content (%), milk solids-not-fat content (%), milk total solids content (%); technological properties of milk – ti­tra­tab­le acidity (SH), active acidity (pH), rennet coagulation time (s), quality of curd (class) and somatic cell count as a parameter of udder health.Highly significant differences were found (P < 0.01) between morning milk yield (15.7 kg) and evening milk yield (13.8 kg), between morning milk protein production (0.51 kg) and evening milk protein production (0.45 kg) and between evening milk fat content (4.41 %) and morning milk fat content (3.95 %). A significant difference (P < 0.05) was found between morning milk total solids content (12.62 %) and evening milk total solids content (12.07 %). No significant differences were found between morning (M) and evening (E) values of the remaining parameters: milk fat production (M 0.62 kg; E 0.60 kg), milk protein content (M 3.24 %; E 3.27 %), milk lactose content (M 4.78 %; E 4.86 %), milk solids-not-fat content (M 7.69 %; E 7.71 %), somatic cell count (M 80 000/1 mL; E 101 000/1 mL), titratable aci­di­ty (M 7.75 SH; E 7.64 SH), active acidity (M pH 6.58; E pH 6.61), rennet coagulation time (M 189 s.; E 191 s.), quality of curd (M 1.60 class; E 1.57 class).

Effect of feeding hay vs. silages of various types to dairy cows on feed intake, milk composition and coagulation properties

2020 ◽  
Vol 87 (3) ◽  
pp. 334-340
Author(s):  
Elisa Manzocchi ◽  
Werner Hengartner ◽  
Michael Kreuzer ◽  
Katrin Giller
Keyword(s):  
Dairy Cows ◽  
Milk Yield ◽  
Feed Intake ◽  
Milk Fat ◽  
Fixed Effects ◽  
Experimental Period ◽  
Milk Composition ◽  
Processing Technology ◽  
Maize Silage ◽  
Rennet Coagulation

AbstractThis research paper addresses the hypotheses (1) that milk produced from hay-fed cows differs from that of silage-fed cows and (2) that silage type has an important impact, too. Four diets differing in forage type but with equal estimated milk production potential and a forage:concentrate ratio of 0.85 : 0.15 were compared regarding their effect on feed intake, milk yield and milk properties. The forages tested were hay, grass silage, conventional short-chopped and long-chopped maize silage subjected to a novel processing technology (Shredlage®). Twenty-four dairy cows were fed two of the four diets in two consecutive runs in an incomplete (4 × 2) Latin-square design (n = 12 per diet). Each experimental period lasted 22 d, with 12 d of adaptation and 10 d of sampling. During sampling, feed intake and milk yield were recorded daily, milk composition and coagulation properties were determined four times. The composition of the diet ingredients was analysed weekly. Data were analysed with a mixed model considering feed, period and their interaction as fixed effects. Stage of lactation, milk yield and milk composition from the pre-experimental period were used as covariates in the model. Dry matter intake was lower with the long-chopped processed maize silage compared to the other three groups. There were some diet differences in intakes of net energy for lactation and absorbable protein in the duodenum, but this did not result in changes in milk yield. The milk fat content was higher with the grassland-based diets compared to the maize silage diets. No treatment effect on milk acidity and rennet coagulation properties was observed. In conclusion, there were no indications for specific physico-chemical properties of milk from a hay-based diet, and maize processing technology was not of large effect either. Future investigations should focus on sensory differentiation of the milk produced with different forages.

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