Migratory fat deposition in European quail: a role for prolactin?

1995 ◽  
Vol 146 (1) ◽  
pp. 71-79 ◽  
Author(s):  
T Boswell ◽  
P J Sharp ◽  
M R Hall ◽  
A R Goldsmith
Keyword(s):  
Food Intake ◽  
Body Mass ◽  
Strong Association ◽  
Fat Deposition ◽  
Daily Rhythm ◽  
Plasma Prolactin ◽  
Coturnix Coturnix ◽  
Ad Libitum ◽  
Ovine Prolactin

Abstract The present study addresses the role of prolactin as a regulator of migratory fattening in European quail (Coturnix coturnix). Plasma prolactin levels in captive birds undergoing migratory fattening in an outdoor aviary and in the laboratory were measured by radioimmunoassay with an antibody raised against recombinant-derived chicken prolactin. No strong association between prolactin and migratory fattening was apparent, and prolactin levels were more closely related to daylength, with the highest concentrations being reached on long days. Plasma prolactin profiles were similar in intact and castrated male quail. Prolactin was secreted in a daily rhythm, with the highest concentrations occurring early in the photophase. However, when birds were food-restricted for 50 days during a migratory phase, there was no difference in fat deposition between birds food-deprived for the first half of the daily photophase compared with those deprived for the second half. Fattening was reduced in the food-restricted birds relative to ad libitum-fed controls, but there was no difference in plasma prolactin levels between the groups. Injections of ovine prolactin (4 mg/kg) significantly increased food intake and body mass of birds maintained on long days, but there were no differences in fattening between birds injected in the morning compared with those injected in the afternoon. Collectively, these results do not support a major role for prolactin in the regulation of migratory fat deposition in European quail. Journal of Endocrinology (1995) 146, 71–79

Effects of food intake and food cue exposure on body and weight satisfaction: The moderating role of body mass index (BMI) and dietary restraint

Appetite ◽  
2008 ◽  
Vol 50 (2-3) ◽  
pp. 562
Author(s):  
P. Lattimore ◽  
A. Roefs ◽  
A. Jansen ◽  
A.-K Fett ◽  
N. Geschwind ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Food Intake ◽  
Body Mass ◽  
Dietary Restraint ◽  
Cue Exposure ◽  
Weight Satisfaction ◽  
Moderating Role

scholarly journals Red knots (Calidris canutus islandica) manage body mass with dieting and activity

2020 ◽  
Vol 223 (21) ◽  
pp. jeb231993
Author(s):  
Kimberley J. Mathot ◽  
Eva M. A. Kok ◽  
Piet van den Hout ◽  
Anne Dekinga ◽  
Theunis Piersma
Keyword(s):  
Food Intake ◽  
Metabolic Rate ◽  
Body Mass ◽  
Assimilation Efficiency ◽  
Adaptive Significance ◽  
Fine Scale ◽  
Calidris Canutus ◽  
Predation Danger ◽  
Mitochondrial Efficiency

ABSTRACTMass regulation in birds is well documented. For example, birds can increase body mass in response to lower availability and/or predictability of food and decrease body mass in response to increased predation danger. Birds also demonstrate an ability to maintain body mass across a range of food qualities. Although the adaptive significance of mass regulation has received a great deal of theoretical and empirical attention, the mechanisms by which birds achieve this have not. Several non-exclusive mechanisms could facilitate mass regulation in birds. Birds could regulate body mass by adjusting food intake (dieting), activity, baseline energetic requirements (basal metabolic rate), mitochondrial efficiency or assimilation efficiency. Here, we present the results of two experiments in captive red knots (Calidris canutus islandica) that assess three of these proposed mechanisms: dieting, activity and up- and down-regulation of metabolic rate. In the first experiment, knots were exposed to cues of predation risk that led them to exhibit presumably adaptive mass loss. In the second experiment, knots maintained constant body mass despite being fed alternating high- and low-quality diets. In both experiments, regulation of body mass was achieved through a combination of changes in food intake and activity. Both experiments also provide some evidence for a role of metabolic adjustments. Taken together, these two experiments demonstrate that fine-scale management of body mass in knots is achieved through multiple mechanisms acting simultaneously.

The role of prolactin in the reactivation of hair follicles in relation to moulting in cashmere goats

1994 ◽  
Vol 143 (3) ◽  
pp. 441-448 ◽  
Author(s):  
P Dicks ◽  
A J F Russel ◽  
G A Lincoln
Keyword(s):  
Prolactin Secretion ◽  
Hair Follicles ◽  
Plasma Prolactin ◽  
Dose Rates ◽  
Significant Difference ◽  
Natural Photoperiod ◽  
Cashmere Goats ◽  
Ovine Prolactin ◽  
Voluntary Food Intake

Abstract The effects of the suppression or elevation of plasma prolactin concentrations in spring on the timing of the reactivation of the hair follicles and the timing of the spring moult were investigated in cashmere goats. Thirty eight adult female goats, housed under conditions of natural photoperiod at 55°55′N from mid-December until May, were allocated to four groups starting on 5 January: ten served as untreated controls, eight received 2 mg ovine prolactin subcutaneously every 12 h for 7 weeks (PRL), twelve received 35 mg bromocriptine intramuscularly every 14 days for 17 weeks (BCR) and eight received injections of both ovine prolactin and bromocriptine at the above dose rates for 7 weeks (PRL+BCR). In the PRL group there was an earlier reactivation of the secondary hair follicles (PRL vs control, proportion of secondary follicles in anagen, weeks 1–5, P<0·01) associated with an earlier moult of secondary fibres (cashmere) but no significant difference in the activity of the primary hair follicles. In the BCR group there was a delay in the reactivation of both the secondary and primary hair follicles (BCR vs control, proportion of secondary and primary hair follicles in anagen, weeks 5–13, P<0·01) and a delay in the moult. In the PRL+BCR group there was an early reactivation and moult similar to the PRL group. Voluntary food intake (VFI) and liveweight were also measured. Only in the BCR group was there a decrease in VFI compared with the controls but with no effect on liveweight. It was concluded that the seasonal increase in prolactin secretion which normally occurs in spring is causally involved in the reactivation of primary and secondary hair follicles and moulting in cashmere goats. Journal of Endocrinology (1994) 143, 441–448

scholarly journals Oxytocinergic cells of the posterior hypothalamic paraventricular nucleus participate in the food entrained clock

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Mario Caba ◽  
Enrique Meza ◽  
Carolina Escobar ◽  
Angeles Jiménez ◽  
Mario Daniel Caba-Flores ◽  
...  
Keyword(s):  
Food Intake ◽  
Hypothalamic Nucleus ◽  
Restricted Feeding ◽  
Adult Rats ◽  
Peripheral Oscillators ◽  
Food Anticipatory Activity ◽  
Ad Libitum ◽  
Anticipatory Activity ◽  
Oxytocinergic Cells

AbstractThe mechanisms underlying food anticipatory activity are still poorly understood. Here we explored the role of oxytocin (OT) and the protein c-Fos in the supraoptic nucleus (SON), medial (PVNm) and posterior (PVNp) regions of the paraventricular hypothalamic nucleus. Adult rats were assigned to one of four groups: scheduled restricted feeding (RF), ad libitum (AL), fasting after restricted feeding (RF-F), to explore the possible persistence of oscillations, or ad libitum fasted (AL-F). In the SON and in the PVNm, OT cells were c-Fos positive after food intake; in contrast, OT cells in the PVNp showed c-Fos activation in anticipation to food access, which persisted in RF-F subjects. We conclude that OT and non-OT cells of the SON and PVNm may play a role as recipients of the entraining signal provided by food intake, whereas those of the PVNp which contain motor preautonomic cells that project to peripheral organs, may be involved in the hormonal and metabolic anticipatory changes in preparation for food presentation and thus, may be part of a link between central and peripheral oscillators. In addition, due to their persistent activation they may participate in the neuronal network for the clock mechanism that leads to food entrainment.

scholarly journals Oxytocinergic Cells of the Posterior Hypothalamic Paraventricular Nucleus Participate in the Food Entrained Clock

2021 ◽  
Author(s):  
Mario Caba ◽  
Enrique Meza ◽  
Carolina Escobar ◽  
Angeles Jiménez ◽  
Mario Daniel Caba-Flores ◽  
...  
Keyword(s):  
Food Intake ◽  
Hypothalamic Nucleus ◽  
Restricted Feeding ◽  
Adult Rats ◽  
Peripheral Oscillators ◽  
Food Anticipatory Activity ◽  
Ad Libitum ◽  
Anticipatory Activity ◽  
Oxytocinergic Cells

Abstract The mechanisms underlying food anticipatory activity is still not well understood. Here we explored the role of oxytocin (OT) and the protein c-Fos in the supraoptic nucleus (SON) and in the medial (PVNm) and posterior (PVNp) regions of the paraventricular hypothalamic nucleus. Adult rats were assigned to one of four groups: scheduled restricted feeding (RF), Ad libitum (AL), fasting after restricted feeding (RF-F), to explore the possible persistence of oscillations, or Ad libitum fasted (AL-F). In the SON and in the PVNm, OT cells were c-Fos positive after food intake; contrasting, OT cells in the PVNp showed c-Fos activation in anticipation to food access, which persisted in RF-F subjects. We conclude that OT cells of the SON and PVNm may play a role as recipients of the entraining signal provided by food intake, whereas those of the PVNp which contain motor preautonomic cells that project to peripheral organs, may be involved in the hormonal and metabolic anticipatory changes in preparation for food presentation and thus, may be part of a link between central and peripheral oscillators. In addition, due to their persistent activation they may participate in the neuronal network for the clock mechanism that leads to food entrainment.

Role of hormones in glucose-6-phosphate dehydrogenase adaptation of rat liver

1962 ◽  
Vol 202 (3) ◽  
pp. 401-406 ◽  
Author(s):  
Helen M. Tepperman ◽  
Jay Tepperman
Keyword(s):  
Food Intake ◽  
Hormone Treatment ◽  
Additional Increase ◽  
Phosphogluconate Dehydrogenase ◽  
Hypophysectomized Rats ◽  
Ad Libitum ◽  
Glucose 6 Phosphate Dehydrogenase ◽  
Determining Factor ◽  
Rule Out

The hepatic enzymes glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase increase markedly in activity on refeeding after a 48-hr fast in the intact rat, but fail to do so in the hypophysectomized animal. Treatment with somatotrophin, cortisone, and thyroid hormone individually and in pairs failed to restore this adaptation to refeeding, but a combination of the three repaired the defect. Similar observations were made on increases in these enzymes in response to fructose feeding in ad libitum-fed hypophysectomized rats. Triple hormone-treated animals in which the enzyme increase in response to fructose feeding was restored were the only ones which gained weight. To rule out possible effects of variations in food intake as a determining factor in the response, hypophysectomized rats fed measured amounts of a starch-fructose diet by stomach tube were compared with suitable controls. A striking increase in enzyme activity occurred in these animals even when no hormone treatment was given, and no additional increase could be induced by treating with the three hormones. It is concluded that the liver cell of the hypophysectomized rat has an autonomous capacity to modify its enzyme profile selectively without the direction or support of hormones of pituitary origin. These hormones may exert their effects in ad libitum-fed animals by influencing food intake and intestinal hexose absorption rates.

Abstract P249: ICV Infusion Of AgRP Modulates Feeding Behavior And Energy Expenditure In Mice

Hypertension ◽  
2020 ◽  
Vol 76 (Suppl_1) ◽  
Author(s):  
Vanessa Oliveira ◽  
Kirthikaa Balapattabi ◽  
John J Reho ◽  
Sebastiao D Silva ◽  
Chetan N Patil ◽  
...  
Keyword(s):  
Food Intake ◽  
Energy Expenditure ◽  
Feeding Behavior ◽  
Body Mass ◽  
High Dose ◽  
Digestive Efficiency ◽  
Genetic Ablation ◽  
Total Food Intake ◽  
Intracerebroventricular Infusion

A subset of Agouti-related protein (AgRP) neurons within the arcuate nucleus express angiotensin type 1a receptors (AT1A), and genetic ablation of AT1A in these cells disinhibits AgRP gene expression and attenuates energy expenditure (EE) in mice. To further understand the role of AgRP in metabolic control, and to establish relevant dosing schedules in this species, here we tested the effect of intracerebroventricular infusion (icv) of recombinant AgRP on metabolic functions in C57BL/6J male mice. First, we examined the effects of AgRP(82-132) (21 days, 1 or 10 nmol/d, icv) or artificial cerebrospinal fluid (aCSF) using metabolic cages. High dose AgRP reduced body mass (aCSF n=12, +0.8±0.6 vs 1 nmol/d n=14, +0.6±0.6 vs 10 nmol/d n=11, -1.5±0.5 p<0.05 g/21d), without affecting food intake (15.1±1.2 vs 14.1±1.1 vs 16.3±1.1 kcal/d) or digestive efficiency (85.2±0.5 vs 84.5±0.7 vs 85.1±0.6 %), but a significant reduction in energy efficiency (+3.8±2.0 vs +2.7±2.8 vs -5.9±2.2 p<0.05 mg/kcal) indicated increased total EE. Next, we examined the effect of AgRP(82-132) (14 days, 1 nmol/d, icv) using a multiplexed system (Promethion, Sable). AgRP had no effect on body mass (25.1±1.2, n=8 vs 26.7±0.5, n=8), overall body composition (by NMR), heat production (Weir, 24h: 0.485±0.015 vs 0.490±0.022 kcal/h), or respiratory exchange ratio (0.88±0.01 vs 0.89±0.01). AgRP increased total food intake (10.1±0.6, n=8 vs 11.9±0.5, n=8, kcal/d, p=0.03) through a synergistic effect on number of meals and median meal mass. We conclude that AgRP (1-10 nmol/d, 2-3 wk, icv) infusion causes subtle changes in feeding behavior without effect on digestive efficiency. In contrast, EE is paradoxically increased by AgRP when infused at a high dose (10 nmol/d). We postulate that these differences may reflect differential accessibility of the peptide to relevant feeding vs autonomic control regions of the hypothalamus when infused into the cerebral ventricles, and/or compensatory increases in EE secondary to changes in feeding behavior. Future studies to deconvolute the role of AgRP in the control of EE in mice will require site-specific delivery of the peptide to relevant target regions or manipulation of its receptor in those regions. Funding: HL134850, HL084207

Effects of food restriction on body mass, energy metabolism and thermogenesis in a tree shrew (Tupaia belangeri)

2018 ◽  
Author(s):  
Xue-na Gong ◽  
Hao Zhang ◽  
Di Zhang ◽  
Wan-long Zhu
Keyword(s):  
Food Intake ◽  
Metabolic Rate ◽  
Body Mass ◽  
Food Restriction ◽  
Tree Shrew ◽  
Tree Shrews ◽  
Tupaia Belangeri ◽  
Brown Adipose ◽  
Food Shortages ◽  
Ad Libitum

AbstractThis study investigates the energy strategies of a small mammal in response to food shortages as a function of food restriction (FR), metabolic rate and ambient temperature. We subjected tree shrews (Tupaia belangeri) to FR and measured body mass, survival rate, resting metabolic rate (RMR), nonshivering thermogenesis (NST) and cytochrome c oxidase (COX) activity of brown adipose tissue (BAT). Cold-exposed animals restricted to 80% of ad libitum food intake had significantly increased RMR and NST and decreased body mass and survival rates compared with those kept at room temperature on the same FR level. Animals classified has having a high RMR consumed 30.69% more food than those classified as having a low RMR, but showed no differences in body mass or survival when restricted to 80% of ad libitum food intake. These results indicate that tree shrews, known for their relatively high metabolic rates, are sensitive to periods of FR, which supports the metabolic switch hypothesis. Our findings are also consistent with the prediction that small mammals with food hoarding behaviors, like tree shrews, may have a lower tolerance for food shortages than non-hoarding species.

scholarly journals Effects of stochastic food deprivation on energy budget, body mass and activity in Swiss mice

2009 ◽  
Vol 55 (4) ◽  
pp. 249-257 ◽  
Author(s):  
Zhijun Zhao ◽  
Jing Cao ◽  
Ye Tian ◽  
Ruirui Wang ◽  
Guiying Wang
Keyword(s):  
Food Intake ◽  
Metabolic Rate ◽  
Body Mass ◽  
Food Deprivation ◽  
Energy Budget ◽  
Resting Metabolic Rate ◽  
General Activity ◽  
Swiss Mice ◽  
Ad Libitum ◽  
Shivering Thermogenesis

Abstract When small animals are faced with an unpredictable food supply, they can adapt by altering different components of their energy budget such as energy intake, metabolic rate, rate of non-shivering thermogenesis (NST) or behaviour. The present study examined the effect of stochastic food deprivation (FD) on body mass, food intake, resting metabolic rate (RMR), NST and behaviour in male Swiss mice. During a period of 4 weeks’ FD, animals were fed ad libitum for a randomly assigned 4 days each week, but were deprived of food for the other 3 days. The results showed that body mass significantly dropped on FD days compared to controls. Food intake of FD mice increased significantly on ad libitum days, ensuring cumulative food intake, final body mass, fat mass, RMR and NST did not differ significantly from controls. Moreover, gastrointestinal tract mass increased in FD mice, but digestibility decreased. In general, activity was higher on deprived days, and feeding behaviour was higher on ad libitum days suggesting that Swiss mice are able to compensate for stochastic FD primarily by increasing food intake on ad libitum days, and not by reducing energy expenditure related to RMR or NST.

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