scholarly journals An Experimental Study of the Influence of Sensory Nerve Fibers on Merkel Cell Differentiation in the Labial Mucosa of the Rabbits

1983 ◽  
Vol 46 (4) ◽  
pp. 469-477 ◽  
Author(s):  
Tamiko TACHIBANA ◽  
Yasunori SAKAKURA ◽  
Kiyoto ISHIZEKI ◽  
Shuichi IIDA ◽  
Tokio NAWA
Keyword(s):  
Experimental Study ◽  
Cell Differentiation ◽  
Sensory Nerve ◽  
Nerve Fibers ◽  
Merkel Cell

scholarly journals EFEKTIVITAS PIJAT PUNGGUNG TERHADAP INTENSITAS NYERI REMATIK SEDANG PADA WANITA LANJUT USIA DI DESA KARYAWANGI KABUPATEN BANDUNG BARAT

2017 ◽  
Vol 3 (1) ◽  
pp. 53
Author(s):  
Pera Siahaan ◽  
Nurhayati Siagian ◽  
Yunus Elon
Keyword(s):  
Rheumatoid Arthritis ◽  
Experimental Study ◽  
Sensory Nerve ◽  
Pain Scale ◽  
Nerve Fibers ◽  
Young Age ◽  
Rheumatic Pain ◽  
Joint Problem ◽  
Before And After ◽  
Back Massage

ABSTRAK Pendahuluan: Rematik merupakan masalah persendian yang menimbulkan rasa nyeri baik wanita maupun laki-laki dan sering terjadi pada orang tua dibandingkan pada usia muda. Penanganan yang tepat untuk menangani rematik secara nonfarmakologis salah satunya adalah pijat punggung. Pijat punggung dapat menurunkan rasa nyeri, hal ini disebabkan pijat punggung menghasilkan pelepasan endorphin serta menstimulasi serabut saraf sensorik delta –A dan serabut C sehingga menurunkan impuls nyeri. Penelitian ini dilakukan untuk mengetahui efektifitas pijat punggung terhadap intensitas skala nyeri sedang pada wanita lanjut usia di Desa Karyawangi Kabupaten Bandung Barat. Penelitian ini merupakan penelitian eksperimen dengan one group pretest-posttest designt. Subjek dalam penelitian ini sebanyak 17 orang sesuai dengan kriteria penelitian. Tingkat nyeri rematik menggunakan Rheumatoid Arthritis Pain Scale (RAPS). Perolehan data nyeri rematik sebelum dan sesudah pemberian intervensi dihitung menggunakan rumus mean. Kemudian dilanjutkan dengan uji statistik melaui uji-t sampel paired. Hasil uji statistik pada pijat punggung menunjukkan bahwa thitung (8,641) > ttabel (2,120) dengan taraf kepercayaan 95% α = 0,05 yang berarti bahwa Ho yang menyatakan tidak ada perbedaan pemberian pijat punggung pada wanita lanjut usia di Desa Karyawangi Kabupaten Bandung Barat di tolak. Kesimpulan dari penelitian ini adalah terdapat penurunan yang signifikan terhadap penurunan skala nyeri rematik pada wanita lanjut usia di Desa Karyawangi Kabupaten Bandung Barat. Diskusi: Pemberian intervensi pijat punggung selama dua hari dapat menurunkan skala nyeri sedang rematik.   Kata Kunci: Nyeri Rematik, Pijat Punggung   ABSTRACT Introduction: Rheumatism is a joint problem that it was happen in both women and men also often going on old man than at a young age. The best proper handling to handle rheumatism in nonfarmakologi in one exception is backing massage. Back massage can reduce pain this is because back massage produce to release of endorphin and stimulate sensory nerve fibers-A delta and fibers C thus reducing pain impulses. This study was conducted to know the effectiveness of back massage to scale the intensity of pain was in women aged in Karyawangi Village West Bandung. This study was an experimental study with one group pretest and postest design. Subjects of this study were 17 in accordance with the criteria. The level of rheumatism pain data before and after intervention administration was calculated using mean formula and continued with statistic test through paired test-t sample. The result of statistic test of back massage was showed that tcount (8,642) > ttable (2,120) with level of confidence 95 % α = 0,05 it mean that Ho there is no significance different administration in back massage for elder women in Karyawangi Village West Bandung Rejected. The conclusion from the study there was decrease in scale a rheumatic pain in women aged in Karyawangi Village West Bandung. Discussion: The gived of intervention is backing massage can reduce pain often. Keywords: Rheumatic pain, Back Massage

Localization of Merkel cells at hairless and hairy human skin sites using keratin 18

1995 ◽  
Vol 73 (9-10) ◽  
pp. 635-639 ◽  
Author(s):  
Julie Fradette ◽  
Marie-Josée Godbout ◽  
Martine Michel ◽  
Lucie Germain
Keyword(s):  
Human Skin ◽  
Basal Layer ◽  
Sensory Nerve ◽  
Neurosecretory Cells ◽  
Nerve Fibers ◽  
Hair Follicles ◽  
Merkel Cells ◽  
Merkel Cell ◽  
Skin Receptor ◽  
And Function

Merkel cells are neurosecretory cells of the skin with epithelial features such as desmosomes and expression of keratins 8, 18, 19, and 20. Merkel cells are scarcely distributed in adult human skin. Although they are present in hair follicles, their density is higher at hairless anatomic sites such as palms and soles. These cells are often innervated by sensory nerve fibers and are thought to be specialized mechanosensory skin receptor cells. However, their precise origin and function are not clearly established. The aim of this study was to localize Merkel cells in human hairless and hairy skin by immunohistochemistry with antibodies Ks18.174 and Ks19.1 directed against keratins 18 and 19, respectively. In glabrous skin of palm and sole, Merkel cells have been localized at the bottom of the rete ridges, in the epidermal basal layer. To study Merkel cell distribution at hairy anatomic sites, we have chosen breast skin, a tissue containing small hair follicles typical of those covering most of the body's surface. Merkel cells were present in the interfollicular epidermis. In hair follicles, they have been identified in the isthmus region.Key words: skin, human, Merkel cell, keratin, hair follicle.

scholarly journals Axon typing of rat muscle nerves using a double staining procedure for cholinesterase and carbonic anhydrase.

1991 ◽  
Vol 39 (12) ◽  
pp. 1617-1625 ◽  
Author(s):  
M J Szabolcs ◽  
A Windisch ◽  
R Koller ◽  
M Pensch
Keyword(s):  
Carbonic Anhydrase ◽  
Cross Sections ◽  
Sensory Nerve ◽  
Histological Section ◽  
Trapezius Muscle ◽  
Motor Units ◽  
Conventional Technique ◽  
Nerve Fibers ◽  
Staining Procedure ◽  
Muscle Nerve

We developed a method for detecting activity of axonal cholinesterase (CE) and carbonic anhydrase (CA)--markers for motor and sensory nerve fibers (NFs)--in the same histological section. To reach this goal, cross-sections of muscle nerves were sequentially incubated with the standard protocols for CE and CA histochemistry. A modified incubation medium was used for CA in which Co++ is replaced by Ni++. This avoids interference of the two histochemical reactions because Co++ binds unspecifically to the brown copper-ferroferricyanide complex representing CE activity, whereas Ni++ does not. Cross-sections of the trapezius muscle nerve containing efferent and afferent NFs in segregated fascicles showed that CE activity was confined to motor NFs. Axonal CA was detected solely in sensory NFs. The number of labeled motor and sensory NFs determined in serial cross-sections stained with either the new or the conventional technique was not significantly different. Morphometric analysis revealed that small unreactive NFs (diameter less than 5 microns) are afferent, medium-sized ones (5 microns less than d less than 7 microns) are unclassifiable, and large ones (d greater than 7 microns) are efferent. The heterogenous CE activity of thick (alpha) motor NFs is linked to the type of their motor units. "Fast" motor units contain CE reactive NFs; "slow" ones have CE negative neurites.

scholarly journals Prion Infection of Skeletal Muscle Cells and Papillae in the Tongue

2004 ◽  
Vol 78 (13) ◽  
pp. 6792-6798 ◽  
Author(s):  
Ellyn R. Mulcahy ◽  
Jason C. Bartz ◽  
Anthony E. Kincaid ◽  
Richard A. Bessen
Keyword(s):  
Skeletal Muscle ◽  
Sensory Nerve ◽  
Meat Products ◽  
Muscle Cells ◽  
Nerve Fibers ◽  
Skeletal Muscle Cells ◽  
Lingual Papillae ◽  
Intracerebral Inoculation ◽  
Axon Terminals ◽  
Prion Infection

ABSTRACT The presence of the prion agent in skeletal muscle is thought to be due to the infection of nerve fibers located within the muscle. We report here that the pathological isoform of the prion protein, PrPSc, accumulates within skeletal muscle cells, in addition to axons, in the tongue of hamsters following intralingual and intracerebral inoculation of the HY strain of the transmissible mink encephalopathy agent. Localization of PrPSc to the neuromuscular junction suggests that this synapse is a site for prion agent spread between motor axon terminals and muscle cells. Following intracerebral inoculation, the majority of PrPSc in the tongue was found in the lamina propria, where it was associated with sensory nerve fibers in the core of the lingual papillae. PrPSc staining was also identified in the stratified squamous epithelium of the lingual mucosa. These findings indicate that prion infection of skeletal muscle cells and the epithelial layer in the tongue can be established following the spread of the prion agent from nerve terminals and/or axons that innervate the tongue. Our data suggest that ingestion of meat products containing prion-infected tongue could result in human exposure to the prion agent, while sloughing of prion-infected epithelial cells at the mucosal surface of the tongue could be a mechanism for prion agent shedding and subsequent prion transmission in animals.

Lumbosacral intersegmental epispinal axons and ectopic ventral nerve rootlets

1987 ◽  
Vol 67 (2) ◽  
pp. 269-277 ◽  
Author(s):  
Wesley W. Parke ◽  
Ryo Watanabe
Keyword(s):  
Nerve Root ◽  
Sensory Nerve ◽  
Conus Medullaris ◽  
Spinal Nerve ◽  
Nerve Fibers ◽  
Ventral Horn ◽  
Spinal Nerve Roots ◽  
Nerve Roots ◽  
Content Type ◽  
Almost All

✓ An epispinal system of motor axons virtually covers the ventral and lateral funiculi of the human conus medullaris between the L-2 and S-2 levels. These nerve fibers apparently arise from motor cells of the ventral horn nuclei and join spinal nerve roots caudal to their level of origin. In all observed spinal cords, many of these axons converged at the cord surface and formed an irregular group of ectopic rootlets that could be visually traced to join conventional spinal nerve roots at one to several segments inferior to their original segmental level; occasional rootlets joined a dorsal nerve root. As almost all previous reports of nerve root interconnections involved only the dorsal roots and have been cited to explain a lack of an absolute segmental sensory nerve distribution, it is believed that these intersegmental motor fibers may similarly explain a more diffuse efferent distribution than has previously been suspected.

HISTOLOGY AND HISTOCHEMISTRY OF THE PINEAL ORGAN IN THE SOCKEYE SALMON, ONCORHYNCHUS NERKA WALBAUM

1967 ◽  
Vol 45 (1) ◽  
pp. 117-126 ◽  
Author(s):  
M. A. Hafeez ◽  
P. Ford
Keyword(s):  
Sockeye Salmon ◽  
Pineal Organ ◽  
Subcommissural Organ ◽  
Sensory Nerve ◽  
Nerve Fibers ◽  
Supporting Cells ◽  
Dependent Behavior ◽  
Aldehyde Fuchsin ◽  
Pineal Nerve ◽  
The Brain

The morphohistology and some histochemical aspects of the pineal organ in the sockeye salmon were studied. The distal part of the organ lies in a pineal fossa in the cranial roof. Photosensory cells and two kinds of ependymal supporting cells are present throughout its epithelium, which is entirely devoid of either melanin or lipofuchsin. Besides sensory nerve fibers, efferent end-loops are present on the photosensory as well as the supporting cells. The dorsal pineal nerve tract probably contains both sensory and efferent fibers. The apocrine secretion of sensory as well as some supporting cells is probably associated with either the maintenance of a constant chemical composition of the cerebrospinal fluid or with supply of certain chemical substances to the brain tissue. The secretion in the pineal and the subcommissural organ consists of glycogen, mucopolysaccharides, mucoproteins, and aldehyde fuchsin positive granules.It is proposed that the pineal organ is photosensory as well as secretory and that its photosensitivity might be of some significance in the light-dependent behavior of this species in terms of intensity detection.

P 25. Investigating cytoskeletal integrity in the sensory nerve fibers in healthy individuals

2021 ◽  
Vol 132 (8) ◽  
pp. e11-e12
Author(s):  
K. Metzner ◽  
A. Rödiger ◽  
N. Gaur ◽  
R. Steinbach ◽  
H. Axer ◽  
...  
Keyword(s):  
Sensory Nerve ◽  
Nerve Fibers ◽  
Healthy Individuals

Functional relationships between sensory nerve fibers and mast cells of dura mater in normal and inflammatory conditions

Neuroscience ◽  
1997 ◽  
Vol 77 (3) ◽  
pp. 829-839 ◽  
Author(s):  
V Dimitriadou ◽  
A Rouleau ◽  
M.D Trung Tuong ◽  
G.J.F Newlands ◽  
H.R.P Miller ◽  
...  
Keyword(s):  
Mast Cells ◽  
Dura Mater ◽  
Sensory Nerve ◽  
Nerve Fibers ◽  
Functional Relationships ◽  
Inflammatory Conditions

scholarly journals Fast-spiking GABA circuit dynamics in the auditory cortex predict recovery of sensory processing following peripheral nerve damage

eLife ◽  
2017 ◽  
Vol 6 ◽  
Author(s):  
Jennifer Resnik ◽  
Daniel B Polley
Keyword(s):  
Peripheral Nerve ◽  
Auditory Cortex ◽  
Sensory Processing ◽  
Cortical Neurons ◽  
Sensory Nerve ◽  
Intracortical Inhibition ◽  
Nerve Fibers ◽  
Nerve Damage ◽  
Inhibitory Neurons ◽  
Sound Processing

Cortical neurons remap their receptive fields and rescale sensitivity to spared peripheral inputs following sensory nerve damage. To address how these plasticity processes are coordinated over the course of functional recovery, we tracked receptive field reorganization, spontaneous activity, and response gain from individual principal neurons in the adult mouse auditory cortex over a 50-day period surrounding either moderate or massive auditory nerve damage. We related the day-by-day recovery of sound processing to dynamic changes in the strength of intracortical inhibition from parvalbumin-expressing (PV) inhibitory neurons. Whereas the status of brainstem-evoked potentials did not predict the recovery of sensory responses to surviving nerve fibers, homeostatic adjustments in PV-mediated inhibition during the first days following injury could predict the eventual recovery of cortical sound processing weeks later. These findings underscore the potential importance of self-regulated inhibitory dynamics for the restoration of sensory processing in excitatory neurons following peripheral nerve injuries.

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