Associations between metabolic syndrome and reduced lung function in young people

Aim. To reveal possible associations between metabolic syndrome (MS) and reduced lung function. Subjects and methods. In 2013—016, a cross-sectional survey was conducted in 908 Novosibirsk dwellers, which included spirometry to evaluate external respiratory function (ERF). For the detection of MS, the investigators used the 2009 All-Russian Research Society of Cardiologists criteria: waist circumference (WC) > 80 cm for women and >94 cm for men in combination with two of the following criteria: blood pressure (BP) ≥130/85 mm Hg, triglycerides (TG) ≥1.7 mmol/l, high-density lipoproteins (HDL) cholesterol

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Prevalence of the Metabolic Syndrome in Central and South American Immigrant Residents of the Washington, DC, Area

Journal of Nutrition and Metabolism ◽

10.1155/2017/9531964 ◽

2017 ◽

Vol 2017 ◽

pp. 1-6 ◽

Cited By ~ 2

Author(s):

Regina M. Gill ◽

Saira A. Khan ◽

Robert T. Jackson ◽

Marguerite Duane

Keyword(s):

Metabolic Syndrome ◽

Low Income ◽

Mexican Americans ◽

Hdl Cholesterol ◽

Epidemiological Data ◽

Washington Dc ◽

South American ◽

Cross Sectional Survey ◽

Cross Sectional ◽

The Metabolic Syndrome

The objective of this study was to estimate the prevalence of Metabolic Syndrome (MetS) and its risk components and then compare differences in the risk components among low-income, uninsured Central and South American recent immigrants to the USA. This cross-sectional survey sampled 1,042 adult patients from a medical clinic in metropolitan Washington, DC. The overall prevalence of the MetS was 26.9% estimated using the modified harmonized definition. The most common abnormal metabolic indicator for women was an elevated BMI ≥ 30 kg/m2(36.1%), while, for men, it was an elevated triglyceride level (46.5%). The risk of abnormal MetS indicators increased steadily with increasing BMI. The abnormal indicator combination identifying the most subjects with the MetS included the following: high triglycerides, low HDL cholesterol, and obesity. MetS rates were highest among subjects from El Salvador and Honduras, 31.3% and 28.0%, respectively, and lowest among subjects from Bolivia (21.7%). Dyslipidemia and high BMI increased the likelihood of having the MetS, which is consistent with studies on Mexican Americans in the San Antonio Heart Study and studies within Central and South American countries. This study adds new baseline epidemiological data for largely understudied, low-income, and mostly recent immigrant groups.

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PREVALENCE AND CHARACTERISTICS OF METABOLIC SYNDROME PATIENTS IN CIBEBER VILLAGE CIMAHI INDONESIA

10.54052/jhds.v1n1.p27-37 ◽

2021 ◽

Vol 1 (Volume 1 No 1) ◽

pp. 27-37

Author(s):

Iis Inayati Rakhmat ◽

Hadi Jusuf ◽

Sinta Rachmanita

Keyword(s):

Blood Pressure ◽

Metabolic Syndrome ◽

Pap Test ◽

Serum Triglyceride ◽

Hdl Cholesterol ◽

The Elderly ◽

Cross Sectional ◽

Descriptive Research ◽

Cholesterol Levels ◽

Cross Sectional Design

Metabolic syndrome is a health problem that often occurs among populations in Indonesia. Data on the characteristics of patients with metabolic syndrome is still very limited, despite the importance of cardiovascular disease prevention. The study aims to explain the prevalence and characteristics of patients with metabolic syndrome in Indonesia. The research methodology used descriptive research using a cross-sectional design. The number of respondents was seven men and 34 women, counted by consecutive sampling. The data was collected from the SQ-FFQ questionnaire and calculating the DQI-I score, analyzing physical activity through the GPAQ questionnaire converted into METs, measuring blood pressure, taking blood, measuring waist circumference, measuring fasting blood sugar. Through enzymatic tests, Serum triglyceride levels through the enzymatic colorimetric GPO-PAP test and HDL cholesterol levels were measured by the CHODPAP method. The results showed that the prevalence of SM was 20.45%, and the majority were women. The largest age group were the elderly. Most cases of metabolic syndrome have three components, with the largest components being central obesity (100%) and blood pressure (88.89%). Most categories of activity were moderate, and diet quality was low. All metabolic syndrome patients in this study were found not to smoke and not to consume alcohol. Based on these results, it can be concluded that SM incidence was high. Further research is needed regarding the relationship between acquired risk factors and metabolic syndrome.

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Prevalence of metabolic syndrome in 25—45-year-old Novosibirsk dwellers

Terapevticheskii arkhiv ◽

10.17116/terarkh2016881051-56 ◽

2016 ◽

Vol 88 (10) ◽

pp. 51-56 ◽

Cited By ~ 6

Author(s):

M I Voevoda ◽

N A Kovalkova ◽

Yu I Ragino ◽

N Yu Travnikova ◽

D V Denisova

Keyword(s):

Metabolic Syndrome ◽

International Diabetes Federation ◽

Density Lipoprotein ◽

Hdl Cholesterol ◽

Research Society ◽

Population Based ◽

Blood Cholesterol ◽

Cross Sectional ◽

Detection Evaluation ◽

Population Based Survey

Aim. To study the prevalence of metabolic syndrome (MS) and its components in a 25—45-year-old Novosibirsk population. Subjects and methods. The Novosibirsk Research Institute of Internal and Preventive Medicine conducted a cross-sectional population-based survey in one of the typical districts of Novosibirsk in 2013—2015. The survey covered 346 men and 408 women. The criteria of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (NCEP-ATP III, 2001), the International Diabetes Federation (IDF, 2005), the Joint Interim Statement (JIS, 2009), and the All-Russian Research Society of Cardiologists (ARRSC, 2009) were used to detect MS. According to the ARRSC criteria, MS was recorded if a waist circumference (WC) was >80 cm for women and >94 cm for men in conjunction with 2 of the following criteria: a blood pressure ≥130/85 mm Hg, triglycerides (TG) ≥1.7 mmol/l, high-density lipoprotein (HDL) cholesterol

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Metabolic syndrome in outpatients receiving antipsychotic therapy in routine clinical practice: A cross-sectional assessment of a primary health care database

European Psychiatry ◽

10.1016/j.eurpsy.2007.07.005 ◽

2008 ◽

Vol 23 (2) ◽

pp. 100-108 ◽

Cited By ~ 35

Author(s):

Antoni Sicras-Mainar ◽

Milagrosa Blanca-Tamayo ◽

Javier Rejas-Gutiérrez ◽

Ruth Navarro-Artieda

Keyword(s):

Blood Pressure ◽

Health Care ◽

Metabolic Syndrome ◽

Body Mass Index ◽

Primary Health Care ◽

Hdl Cholesterol ◽

Cross Sectional ◽

Primary Health ◽

Health Care Database ◽

Care Database

AbstractObjectiveTo determine the prevalence of metabolic syndrome (MS) in outpatients treated with antipsychotics included in a primary-health-care database.MethodsA cross-sectional study was carried out assessing an administrative outpatients claim-database from 5 primary-health-centers. Subjects on antipsychotics for more than 3 months were included. The control group was formed by the outpatients included in the database without exposition to any antipsychotic drugs. MS was defined according to the modified NCEP-ATP III criteria, and required confirmation of at least 3 of the 5 following components: body mass index >28.8 kg/m2, triglycerides >150 mg/ml, HDL-cholesterol <40 mg/ml (men)/<50 mg/ml (women), blood pressure >130/85 mmHg, and fasting serum glucose >110 mg/dl.ResultsWe identified 742 patients [51.5% women, aged 55.1 (20.7) years] treated with first- or second-generation antipsychotics during 27.6 (20.3) months. Controls were 85.286 outpatients [50.5% women, aged 45.5 (17.7) years]. MS prevalence was significantly higher in subjects on antipsychotics: 27.0% (95% CI, 23.8–30.1%) vs. 14.4% (14.1–14.6%); age- and sex-adjusted OR = 1.38 (1.16–1.65, P < 0.001). All MS components, except high blood pressure, were significantly more prevalent in the antipsychotic group, particularly body mass index >28.8 kg/m2: 33.0% (29.6–36.4%) vs. 17.8% (17.6–18.1%), adjusted OR = 1.63 (1.39–1.92, P < 0.001), and low HDL-cholesterol levels: 48.4% (44.8–52.0%) vs. 29.3% (29.0–29.6%); adjusted OR = 1.65 (1.42–1.93, P < 0.001). Compared with the reference population, subjects with schizophrenia or bipolar disorder (BD), but not dementia, showed a higher prevalence of MS.ConclusionsCompared with the general outpatient population, the prevalence of MS was significantly higher in patients with schizophrenia or BD treated with antipsychotics.

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Associations of resistin with inflammatory and fibrinolytic markers, insulin resistance, and metabolic syndrome in middle-aged and older Chinese

Acta Endocrinologica ◽

10.1530/eje-08-0427 ◽

2008 ◽

Vol 159 (5) ◽

pp. 585-593 ◽

Cited By ~ 37

Author(s):

Qibin Qi ◽

Jing Wang ◽

Huaixing Li ◽

Zhijie Yu ◽

Xingwang Ye ◽

...

Keyword(s):

Insulin Resistance ◽

Metabolic Syndrome ◽

Density Lipoprotein ◽

Hdl Cholesterol ◽

Plasminogen Activator Inhibitor ◽

Population Based ◽

Model Assessment ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Factor Α

ObjectiveResistin increases insulin resistance (IR) in mice. However, the role of resistin in human disease remains controversial. We aimed to assess plasma resistin levels and their associations with inflammatory and fibrinolytic markers, IR and metabolic syndrome (MetS) among Chinese.Design and methodsPlasma resistin was measured in a population-based cross-sectional survey of 3193 Chinese aged from 50 to 70 years in Beijing and Shanghai.ResultsThe median resistin concentration was 8.60 ng/ml (interquartile range, 5.78–14.00) among all participants, and it was higher in women than in men (P=0.008). Resistin was correlated weakly with body mass index, waist circumference, high-density lipoprotein (HDL) cholesterol (negatively), homeostatic model assessment of IR and tumor necrosis factor-α receptor 2 (TNFR2; r=0.04, 0.07, –0.09 and 0.06 respectively, all P<0.05), and more highly with C-reactive protein (CRP), interleukin (IL)6 and plasminogen activator inhibitor (PAI)1 (r=0.12, 0.12 and 0.21 respectively, all P<0.001), but only HDL cholesterol, CRP, IL6, TNFR2, and PAI1 remained significantly associated with resistin in multiple regression analysis (all P<0.05). Furthermore, elevated resistin levels were associated with the higher prevalence of IR and MetS. However, the significant relationships disappeared after adjustment for inflammatory and fibrinolytic markers especially PAI1.ConclusionsThis study suggests that resistin is more strongly associated with inflammatory and fibrinolytic markers than with obesity or IR status. The associations of resistin with IR and MetS could largely be explained by inflammatory and fibrinolytic markers especially PAI1 levels.

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Dietary Approaches to Stop Hypertension (DASH): potential mechanisms of action against risk factors of the metabolic syndrome

Nutrition Research Reviews ◽

10.1017/s0954422419000155 ◽

2019 ◽

Vol 33 (1) ◽

pp. 1-18 ◽

Cited By ~ 9

Author(s):

Masoumeh Akhlaghi

Keyword(s):

Risk Factors ◽

Blood Pressure ◽

Metabolic Syndrome ◽

Saturated Fat ◽

Hdl Cholesterol ◽

Reduce Blood Pressure ◽

Overweight And Obesity ◽

Cross Sectional ◽

Dash Diet ◽

The Metabolic Syndrome

AbstractThe metabolic syndrome is a cluster of disorders dominated by abdominal obesity, hypertriacylglycerolaemia, low HDL-cholesterol, high blood pressure and high fasting glucose. Diet modification is a safe and effective way to treat the metabolic syndrome. Dietary Approaches to Stop Hypertension (DASH) is a dietary pattern rich in fruits, vegetables and low-fat dairy products, and low in meats and sweets. DASH provides good amounts of fibre, K, Ca and Mg, and limited quantities of total fat, saturated fat, cholesterol and Na. Although DASH was initially designed for the prevention or control of hypertension, using a DASH diet has other metabolic benefits. In the present review, the effect of each dietary component of DASH on the risk factors of the metabolic syndrome is discussed. Due to limited fat and high fibre and Ca content, individuals on the DASH diet are less prone to overweight and obesity and possess lower concentrations of total and LDL-cholesterol although changes in TAG and HDL-cholesterol have been less significant and available evidence in this regard is still inconclusive. Moreover, high amounts of fruit and vegetables in DASH provide great quantities of K, Mg and fibre, all of which have been shown to reduce blood pressure. K, Mg, fibre and antioxidants have also been effective in correcting glucose and insulin abnormalities. Evidence is provided from cross-sectional investigations, cohort studies and randomised controlled trials, and, where available, from published meta-analyses. Mechanisms are described according to human studies and, in the case of a lack of evidence, from animal and cell culture investigations.

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Screening for the metabolic syndrome in subjects with migraine

Cephalalgia ◽

10.1177/0333102416672494 ◽

2016 ◽

Vol 37 (12) ◽

pp. 1180-1188 ◽

Cited By ~ 4

Author(s):

Sylvie Streel ◽

Anne-Françoise Donneau ◽

Nadia Dardenne ◽

Axelle Hoge ◽

Adelin Albert ◽

...

Keyword(s):

Metabolic Syndrome ◽

Large Scale ◽

Cardiovascular Health ◽

Smoking Status ◽

Hdl Cholesterol ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Systematic Screening ◽

The Metabolic Syndrome ◽

Low Hdl

Background Metabolic syndrome (MetS) and migraine are known to be associated. This study assessed the risk of MetS and its clinical characteristics in migraine with aura (MA) and without aura (MO) based on a large-scale cross-sectional survey. Methods The study material consisted of 751 participants in the Nutrition, Environment and CardioVascular Health (NESCaV) survey. Diagnosis of migraine was based on the ef-ID migraine questionnaire and MetS was defined according to the Revised-Adult Treatment Panel III criteria. Sociodemographic and risk factors were also recorded. Weighted logistic regression was used to assess the risk of MetS. Results After adjusting for stratification (gender, age, district) and other factors (smoking status, sedentary lifestyle, family history of stroke, myocardial infarction and hypertension), MA subjects were at higher risk of MetS (OR 3.45; 95% CI: 1.63–7.29) while MO individuals were not, when compared to non-migraineurs. When considering MetS components, MA was positively associated with low HDL-cholesterol (OR 2.26; 95% CI: 1.08–4.74), hyperglycemia (OR 2.77; 95% CI: 1.30–5.88) and abdominal obesity (OR 2.03; 95% CI: 1.07–3.86). Conclusion Migraineurs with aura are at higher risk of MetS, suggesting that these subjects, already more exposed to stroke, may benefit from a systematic screening for the metabolic syndrome.

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HDL Triglycerides: A New Marker of Metabolic and Cardiovascular Risk

International Journal of Molecular Sciences ◽

10.3390/ijms20133151 ◽

2019 ◽

Vol 20 (13) ◽

pp. 3151 ◽

Cited By ~ 9

Author(s):

Girona ◽

Amigó ◽

Ibarretxe ◽

Plana ◽

Rodríguez-Borjabad ◽

...

Keyword(s):

Metabolic Syndrome ◽

Cardiovascular Risk ◽

1H Nmr ◽

Metabolic Diseases ◽

Hdl Cholesterol ◽

Cholesterol Content ◽

University Hospital ◽

High Density Lipoproteins ◽

Strong Negative Correlation ◽

Cross Sectional

While cholesterol content in high-density lipoproteins (HDLs) is a well-established inverse marker of cardiovascular risk, the importance of HDL–triglyceride (HDL-TG) concentration is not well known. We aim to examine plasma HDL-TG concentrations, assessed by 1H-NMR, in patients with metabolic diseases and their association with classical biomarkers. In this cross-sectional study, we included 502 patients with type 2 diabetes or metabolic syndrome attending the lipid unit of our University Hospital. The presence of arteriosclerotic plaques was assessed by ultrasonography. A complete lipoprotein profile was performed by 1H-NMR (Liposcale test). HDL-TG was strongly positively correlated with total triglycerides, glycerol, and fatty liver index, while a strong negative correlation was observed with HDL-cholesterol (HDL-C) and HDL-particle number (HDL-P). HDL-TG was associated with all triglyceride-rich lipoprotein parameters and had an opposite association with HDL-C and HDL-P. It was also significantly correlated with circulating cholesterol ester transfer protein (CETP). HDL-TG concentrations were higher as metabolic syndrome components increased. HDL-TG was also higher with worsening glucose metabolism. Patients with carotid plaques also showed higher HDL-TG. In contrast to HDL-C, HDL-TG is directly associated with metabolism and arteriosclerotic vascular alterations. HDL-TG should be considered a biomarker of metabolic and cardiovascular risk and could be a marker of HDL dysfunction.

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Metabolic Syndrome Among Physicians: A Pilot Study from Chattogram, Bangladesh

Chattagram Maa-O-Shishu Hospital Medical College Journal ◽

10.3329/cmoshmcj.v20i2.56477 ◽

2021 ◽

Vol 20 (2) ◽

pp. 65-68

Author(s):

Anisul Awal ◽

Farid Uddin Ahmed

Keyword(s):

Blood Pressure ◽

Metabolic Syndrome ◽

Waist Circumference ◽

Fasting Blood Glucose ◽

Preventive Health Care ◽

Medical College Hospital ◽

High Density Lipoproteins ◽

College Hospital ◽

Cross Sectional ◽

Medical College

Background : Although the information on Metabolic Syndrome (MetS) in the general population from different parts of Bangladesh is available, the information regarding the same is scarcely available from physicians of Bangladesh. This study was aimed to assess the prevalence of MetS among physicians working at Chattogram Medical College Hospital, Bangladesh. Materials and methods : Data was collected for this cross-sectional study from 255 working physicians of Chittagong Medical College Hospital in 2018. The participants filled a structured questionnaire followed by physical and biochemical measurements including waist circumference, blood pressure, lipid profile, and fasting blood glucose. National Cholesterol Education Program’s Adult Treatment Panel III report (ATP III) defines criteria were used to identify physicians with the MetS. Results : Among 255 participants (males - 192 and females - 63), 100 (39.2%) were with MetS. Prevalence of same was higher in females (41.3%) than males (38.5%). The elderly physicians (>40 years) had a higher prevalence compared to the younger (£40 years) physicians [72 (50.3%) vs. 28 (25.0%)]. In the males, low High-Density Lipoproteins-Cholesterol (HDL-C) was the major contributor to the prevalence of MetS followed by high blood pressure. However, in females, low HDL-C and greater waist circumference contributed the maximum to MetS. Conclusion : This study showed a high prevalence of MetS among physicians of Bangladesh, and thereby warrants the urgent implementation of preventive health care strategies to reduce both morbidity and mortality related to this medical problem. Further studies ought to focus on the working conditions and lifestyles of individuals in these high-risk groups. Chatt Maa Shi Hosp Med Coll J; Vol.20 (2); July 2021; Page 65-68

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Metabolic Syndrome and Pulmonary Function Indices

Romanian Journal of Diabetes Nutrition and Metabolic Diseases ◽

10.2478/rjdnmd-2018-0030 ◽

2018 ◽

Vol 25 (3) ◽

pp. 261-269

Author(s):

Gholamreza Pouryaghoub ◽

Ramin Mehrdad ◽

Mohammad Mehraban

Keyword(s):

Metabolic Syndrome ◽

Lung Function ◽

Density Lipoprotein ◽

Forced Expiratory Volume ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Adult Men ◽

Total Prevalence ◽

Independent Association ◽

Restrictive Pattern

Abstract Background and aims: Metabolic syndrome (MetS) is a collection of metabolic risk factors including increased waist circumference (WC), elevated blood pressure (BP), increased triglyceride (TG), decreased high density lipoprotein (HDL-C) and increased fasting blood sugar (FBS). We aimed to examine the relevance between the MetS and its components with reduced lung functions in adult men. Material and method: A total of 3899 adult men underwent screening examination between 2015-2016 in a cross-sectional survey. Results: The mean (± SD) age of our population was 37.25 (± 4.9) years. The overall prevalence of MetS was 7.6%. The total prevalence of reduced lung function in men with MetS was 13.8%. The most common type of reduced lung function was the restrictive pattern (7.1%). The forced expiratory volume of first second (FEV1) and forced vital capacity (FVC) values were significantly lower in men with MetS (both p<0.001). Also these values were significantly lower in diabetic men compared to non-diabetics and those with impaired fasting glucose (IFG). WC and HDL were the most potent predictors of reduced FEV1 and FVC. Conclusions: We obtained a positive independent association between MetS and reduced lung function in adult men which may be related mainly due to increased WC and decreased HDL.

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