scholarly journals Dietary supplements containing prohibited substances: A review (Part 1)

2014 ◽  
Vol 26 (2) ◽  
pp. 59
Author(s):  
Pieter Van der Bijl

Dietary supplements and chemical agents have been used for a number of decades among athletes striving to achieve increased strength and performance. This has led to a huge, growing market for the food supplement industry. The latter’s products are classified as ‘foods’ rather than drugs and are therefore free of the stringent requirements for registration of pharmaceuticals, i.e. no safety and efficacy data are required prior to registration. During the past decade, some dietary supplements have been shown to contain pharmaceutically active components not adequately identified on their package labels. These pharmaceuticals may have unintentionally entered the product or may have been intentionally added. Although the concentrations of these substances may be low and devoid of health or performance-enhancing effects, they may lead to positive doping tests. In Part 1 of this two-part review, a selection of the World Anti-Doping Agency-prohibited illegal stimulants, i.e. ephedrine, pseudoephedrine, sibutramine and methylhexaneamine, are discussed. Certain food supplement labels do mention the presence of natural sources of illegal stimulants, e.g. Ephedra sinica (ephedrine), but do not refer to the chemical entities of ephedrine and its analogues as such. The pharmacological adverse effects of stimulants, in particular those on the cardiovascular system, are briefly reviewed. Suggestions for avoiding these pitfalls are made. 

Author(s):  
Bita SEPEHRI ◽  
Reza GHAFFARI ◽  
Alireza JEDDIAN ◽  
Fariba SALEK ◽  
Robabeh EMROUZI ◽  
...  

Background: The implementation of Family Physician Program (FPP) in Iran during the past decade, despite of its numerous achievements, has faced many challenges. We aimed to compare the implementation and the performance of FPP in Iran with selected countries, in order to analyze those challenges and suggest potential solutions. Methods: This current descriptive-comparative study was conducted in 2015. The implementation and the performance of the FPP in Iran and six countries (Canada, Australia, United Kingdom, Denmark, United States and the Netherlands) were described and compared. The criteria for selection of these countries were the existence of well-established FFPs and ease of access to data required to conduct the research. A documentation checklist of the implementation status and FPP practice was prepared. The checklist’s content validity was established by an independent 10 member expert panel, specializing in the field of Family Medicine. The conclusive checklist was finalized for each country, based on inter-rater agreement of the three researchers and used as a basis for this comparative study. Results: This study revealed significant differences in implementation of the FPP and relatively low differences in FPP performance between Iran and the selected countries. Conclusion: Implementation and performance of FPP and patient referral system in Iran struggles with serious challenges and burdens, in contrast with the selected reviewed countries. As such, modification of the FPP in Iran seems to be a must. Such modification may include developing educational programs for FPs, clearly defining the duties and practices of FPs, and revising their reimbursement and employment status.


2018 ◽  
Vol 9 (2) ◽  
pp. 55-71
Author(s):  
Pratiksha Gautam ◽  
Hemraj Saini

Over the past few decades, many tools and methods have been proposed by several researchers to detect clones automatically in programs and software. Nevertheless, it is not yet clear how to evaluate these tools in terms of accuracy, scalability, and portability. However, all of these tools have some merits and limitations but the application of these tools depends on the user requirements, so it is necessary for the user that they should be aware of the tools and its distinguishing aspects. This article presents the performance of six clone detection tools in terms of accuracy, scalability, and portability. The aim of this study is to make the selection of tools easy for detection of copied code.


2018 ◽  
Vol 6 (3) ◽  
pp. 118-123 ◽  
Author(s):  
Lailan M. Haji ◽  
Subhi R.M. Zeebaree ◽  
Karwan Jacksi ◽  
Diyar Q. Zeebaree

Through the huge growth of heavy computing applications which require a high level of performance, it is observed that the interest of monitoring operating system performance has also demanded to be grown widely. In the past several years since OS performance has become a critical issue, many research studies have been produced to investigate and evaluate the stability status of OSs performance. This paper presents a survey of the most important and state of the art approaches and models to be used for performance measurement and evaluation. Furthermore, the research marks the capabilities of the performance-improvement of different operating systems using multiple metrics. The selection of metrics which will be used for monitoring the performance depends on monitoring goals and performance requirements. Many previous works related to this subject have been addressed, explained in details, and compared to highlight the top important features that will very beneficial to be depended for the best approach selection.


Author(s):  
Michael J Schmid ◽  
Achim Conzelmann ◽  
Claudia Zuber

Talent selection in rowing is often solely based on anthropometric and performance variables, even though psychological characteristics are considered to be important contributors to successful talent development. Because multidimensional talent models and holistic theories represent the state-of-the-art in talent research, we aimed to find patterns connecting psychological and performance variables to future success in rowing. Therefore, 22 coaches rated the achievement-motivated behavior represented by the variables proactivity, ambition and commitment of 65 competitive to high-level athletes ( Mage = 17.2 ± 1.55 years) for the past year (t1). Additionally, the athletes performed several 2,000 m ergometer tests during that same period. At t2 (30 months later), each rower’s performance was evaluated based on the success at different competitions. To examine the results, we used the person-oriented Linking of Clusters after removal of a Residue (LICUR) method to identify the relationships between the achievement-motivated behavior and ergometer results at t1 and the success at t2. The rowers could be assigned to five clusters. Although the highly motivated rowers were not the fastest on the ergometer at t1, they were more likely to be in highest performance level at t2 compared to the other clusters (OR = 3.5, p < .05). By contrast, all the ambitionless rowers and unmotivated rowers were either racing at national level or had dropped out. In conclusion, certain patterns of achievement-motivated behavior and current performance are associated with future success (30 months later). The consideration of achievement-motivated behavior in the selection of rowers seems promising in this context.


2020 ◽  
pp. 133-139
Author(s):  
Sanatan Ratna ◽  
B Kumar

In the past few decades, there has been lot of focus on the issue of sustainability. This has occurred due to the growing concerns related to climate change and the growing awareness about environmental concerns. Also, the competition at global level has led to the search for the most sustainable route in the industries. The current research work deals with the selection of green supplier in a Nickle coating industry based on certain weighted green attributes. For this purpose, a hybrid tool comprising of Fuzzy AHP (Fuzzy Analytical Hierarchy) and VIKOR (VlseKriterijumska Optimizacija I Kompromisno Resenje) is used. The Fuzzy AHP is used for assigning proper weights to the selected criteria for supplier evaluation, while VIKOR is used for final supplier selection based on the weighted criteria. The three criterions for green supplier selection are, Ecological packaging, Corporate socio-environmental responsibility and Staff Training. The outcome of the integrated model may serve as a steppingstone to other SMEs in different sectors for selecting the most suitable supplier for addressing the sustainability issue.


2020 ◽  
Vol 16 (5) ◽  
pp. 685-707 ◽  
Author(s):  
Amna Batool ◽  
Farid Menaa ◽  
Bushra Uzair ◽  
Barkat Ali Khan ◽  
Bouzid Menaa

: The pace at which nanotheranostic technology for human disease is evolving has accelerated exponentially over the past five years. Nanotechnology is committed to utilizing the intrinsic properties of materials and structures at submicroscopic-scale measures. Indeed, there is generally a profound influence of reducing physical dimensions of particulates and devices on their physico-chemical characteristics, biological properties, and performance. The exploration of nature’s components to work effectively as nanoscaffolds or nanodevices represents a tremendous and growing interest in medicine for various applications (e.g., biosensing, tunable control and targeted drug release, tissue engineering). Several nanotheranostic approaches (i.e., diagnostic plus therapeutic using nanoscale) conferring unique features are constantly progressing and overcoming all the limitations of conventional medicines including specificity, efficacy, solubility, sensitivity, biodegradability, biocompatibility, stability, interactions at subcellular levels. : This review introduces two major aspects of nanotechnology as an innovative and challenging theranostic strategy or solution: (i) the most intriguing (bare and functionalized) nanomaterials with their respective advantages and drawbacks; (ii) the current and promising multifunctional “smart” nanodevices.


2017 ◽  
Vol 7 (2) ◽  
pp. 7-25
Author(s):  
Karolina Diallo

Pupil with Obsessive-Compulsive Disorder. Over the past twenty years childhood OCD has received more attention than any other anxiety disorder that occurs in the childhood. The increasing interest and research in this area have led to increasing number of diagnoses of OCD in children and adolescents, which affects both specialists and teachers. Depending on the severity of symptoms OCD has a detrimental effect upon child's school performance, which can lead almost to the impossibility to concentrate on school and associated duties. This article is devoted to the obsessive-compulsive disorder and its specifics in children, focusing on the impact of this disorder on behaviour, experience and performance of the child in the school environment. It mentions how important is the role of the teacher in whose class the pupil with this diagnosis is and it points out that it is necessary to increase teachers' competence to identify children with OCD symptoms, to take the disease into the account, to adapt the course of teaching and to introduce such measures that could help children reduce the anxiety and maintain (or increase) the school performance within and in accordance with the school regulations and curriculum.


Author(s):  
John Hunsley ◽  
Eric J. Mash

Evidence-based assessment relies on research and theory to inform the selection of constructs to be assessed for a specific assessment purpose, the methods and measures to be used in the assessment, and the manner in which the assessment process unfolds. An evidence-based approach to clinical assessment necessitates the recognition that, even when evidence-based instruments are used, the assessment process is a decision-making task in which hypotheses must be iteratively formulated and tested. In this chapter, we review (a) the progress that has been made in developing an evidence-based approach to clinical assessment in the past decade and (b) the many challenges that lie ahead if clinical assessment is to be truly evidence-based.


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