scholarly journals Perforation of the palate - A report of two Syphilitic Gumma cases

2020 ◽  
Vol 75 (6) ◽  
pp. 311-315
Author(s):  
Fadi Titinchi ◽  
Nashreen Behardien ◽  
Jean Morkel ◽  
Johan Opperman
Keyword(s):  
Human Immunodeficiency Virus ◽  
Differential Diagnosis ◽  
Cocaine Abuse ◽  
Bacterial Infections ◽  
Fungal Infections ◽  
Treponema Pallidum ◽  
Definitive Diagnosis ◽  
Tertiary Syphilis ◽  
Immunodeficiency Virus ◽  
Compromised Patients

Syphilis has recently shown resurgence in its incidence especially in immune-compromised patients. We present two cases of tertiary syphilis in middle-aged males with large perforations in the hard and soft palates, one of which had Human Immunodeficiency Virus (HIV) co-infection. Diagnosis was initially difficult due to non-specific features mimicking other conditions such as perforation of cocaine abuse aetiology, neoplastic conditions, sarcoi-dosis, fungal infections, bacterial infections other than Treponema pallidum and Wegeners granulomatosis. With special investigations including Anti-Treponema Immunohistochemistry and histology, however, a definitive diagnosis of syphilitic gumma was reached. Intravenous penicillin was the mainstay of management along with treatment of the underlying medical conditions. A removable acrylic obturator was used to close the oro-nasal fistula to improve swallowing and speech. Syphilis should be included as a differential diagnosis in cases of palatal perforation.

scholarly journals The Antiviral Properties of Cyclosporine. Focus on Coronavirus, Hepatitis C Virus, Influenza Virus, and Human Immunodeficiency Virus Infections

Biology ◽  
2020 ◽  
Vol 9 (8) ◽  
pp. 192 ◽  
Author(s):  
Paulina Glowacka ◽  
Lidia Rudnicka ◽  
Olga Warszawik-Hendzel ◽  
Mariusz Sikora ◽  
Mohamad Goldust ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Influenza Virus ◽  
Hepatitis C ◽  
Beneficial Effect ◽  
Bacterial Infections ◽  
Viral Infections ◽  
Skin Diseases ◽  
Current Knowledge ◽  
Immunosuppressive Treatment ◽  
Immunodeficiency Virus

This review updates current knowledge regarding the risk of viral infections, including COVID-19, in patients treated with cyclosporine. We also shortly refer to bacterial infections and parasitic infestations in patients treated with cyclosporin. Cyclosporine is an immunosuppressive drug, which is widely used in medicine, including in the treatment of autoimmune skin diseases in dermatology, rheumatology, ophthalmology and nephrology, and in organ transplantation. A usual concern associated with immunosuppressive treatment is the potential risk of infections. Interestingly, several data indicate a relatively low risk of infections, especially viral infections, in patients receiving cyclosporine. It was shown that cyclosporine exerts an inhibitory effect on the replication of some viruses, or may have a potentially beneficial effect on the disease course in infections. These include hepatitis C, influenza virus, rotavirus, human immunodeficiency virus and coronavirus infections. Available data indicate that cyclosporine may have a beneficial effect on COVID-19, which is caused by the coronavirus SARS-COV2.

scholarly journals Prevalence of Sexually Transmitted Diseases and Transmission of HIV in Dhaka, Bangladesh

2009 ◽  
Vol 3 (1) ◽  
pp. 27-33
Author(s):  
Tahmina Shirin ◽  
Saidur Rahman ◽  
Fareha Jesmin Rabbi ◽  
Md Humayun Kabir ◽  
KZ Mamun
Keyword(s):  
Human Immunodeficiency Virus ◽  
Herpes Simplex ◽  
Chlamydia Trachomatis ◽  
Sexually Transmitted Diseases ◽  
Treponema Pallidum ◽  
Enzyme Linked Immunosorbent Assay ◽  
Sexually Transmitted ◽  
Immunodeficiency Virus ◽  
Simplex Virus

The prevalence of sexually transmitted diseases (STDs) among patients attending out patients department of Skin and Venereal diseases of Dhaka Medical College Hospital, Dhaka and Shahid Sohrawardy Hospital, Dhaka was studied. A total of 230 patients were enrolled in the study during the period of July, 2006 to May, 2007. Urethral and endocervical swabs were collected from the participants for detection of Neisseria gonorrheae (by culture), Chlamydia trachomatis (by immunochromatoghraphy) and blood samples for the detection of Treponema pallidum antibody (by rapid plasma regain and Treponema pallidum haemagglutination assay), Herpes simplex virus type 2 antibody (both IgM and IgG by enzyme linked immunosorbent assay) and Human Immunodeficiency virus antibody (by enzyme linked immunosorbent assay). Socio-demographic data and data regarding high-risk sexual behavior were also collected. Out of 230 participants, 199 (86.5%) were positive for STDs pathogens studied, among them, 98 (42.6%) were infected with single pathogen and 101 (43.9%) were suffering from multiple infections. The prevalences of N. gonorrheae, C. trachomatis, T. pallidum, and HSV type 2 were 90 (39.1%), 110 (47.8%), 28 (12.2%) and 88 (38.2%) respectively. However, none of them were positive for HIV infection. Use of condom was significantly associated with protection of the participants against STDs. Keywords: Sexually Transmitted Diseases, Neisseria gonorrhoeae, Chlamydia trachomatis, Treponema pallidum, Herpes simplex virus type-2, Human Immunodeficiency virus   doi: 10.3329/bjmm.v3i1.2968 Bangladesh J Med Microbiol 2009; 03 (01): 27-33

scholarly journals Trypanosoma cruzi meningoencephalitis and myocarditis in a patient with acquired immunodeficiency syndrome

1993 ◽  
Vol 35 (2) ◽  
pp. 205-208 ◽  
Author(s):  
Ademir Rocha ◽  
Marcelo S. Ferreira ◽  
Sergio A. Nishioka ◽  
Marcos Silva ◽  
Marcius K. N. Burgarelli ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Differential Diagnosis ◽  
Chagas Disease ◽  
Acquired Immunodeficiency Syndrome ◽  
The Other ◽  
Post Mortem ◽  
Immunodeficiency Virus ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome ◽  
Male Heterosexual

We report the case of a 52-year-old male heterosexual patient with acquired immunodeficiency syndrome (AIDS) and reactivation of Chagas' disease manifested by meningoencephalitis and myocarditis, diagnosed post-mortem. Unexplained reactivation of Chagas' disease should be included among the diagnostic criteria of AIDS in human immunodeficiency virus positive patients. On the other hand, AIDS should be considered in the differential diagnosis of patients with unexplained reactivation of Chagas' disease.

CROSSOVER OF PLACEBO PATIENTS TO INTRAVENOUS IMMUNOGLOBULIN CONFIRMS EFFICACY FOR PROPHYLAXIS OF BACTERIAL INFECTIONS AND REDUCTION OF HOSPITALIZATIONS IN HUMAN IMMUNODEFICIENCY VIRUS-INFECTED CHILDREN

PEDIATRICS ◽  
1995 ◽  
Vol 96 (2) ◽  
pp. 408-409
Author(s):  
Alan Alvarado ◽  
David Fuentes ◽  
William T. Shearer
Keyword(s):  
Human Immunodeficiency Virus ◽  
Intravenous Immunoglobulin ◽  
Bacterial Infections ◽  
Immunodeficiency Virus

Monthly IVIG infusions reduced bacterial infections and hospitalizations in HIV-infected children. In this cohort, the benefit obtained from IVIG appeared to be independent of trimethopnim-sulfamethoxazole prophylaxis for PCP, and the benefit persisted for at least 3 years.

scholarly journals Dermatomyositis with Kaposi’s Sarcoma in a Patient without Human Immunodeficiency Virus-1 Infection

1991 ◽  
Vol 5 (1) ◽  
pp. 1-4
Author(s):  
Dana Liang ◽  
Andrew Szilagyi ◽  
Robin C Billick ◽  
Herbert Srolovitz ◽  
Ricardo Bullen
Keyword(s):  
Human Immunodeficiency Virus ◽  
Kaposi's Sarcoma ◽  
Kaposi’S Sarcoma ◽  
Definitive Diagnosis ◽  
Gastrointestinal Involvement ◽  
Cutaneous Lesions ◽  
First Case ◽  
Immunodeficiency Virus ◽  
Human Immunodeficiency Virus 1

The first case of dermatomyositis complicating cutaneous and visceral Kaposi’s sarcoma is presented in a 75-year-old man without human immunodeficiency virus infection. Dermatomyositis preceded a definitive diagnosis of Kaposi’s sarcoma by six months, although in retrospect unrecognized lesions may have presented simultaneously. He was treated with prednisone and azathioprine, thus raising the possibility of the role of immunosuppression in promoting progression of the sarcoma. It is suggested that although the association between dermatomyositis and Kaposi’s sarcoma occurs rarely, dermatomyositis should be considered a paraneoplastic syndrome of Kaposi’s sarcoma. Further, the finding of cutaneous lesions of Kaposi’s sarcoma could predict gastrointestinal involvement when dermatomyositis and Kaposi’s sarcoma occur in the same patient.

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