scholarly journals Emergency slaughter of pigs due to immobility

2012 ◽  
Vol 49 (No. 10) ◽  
pp. 359-364 ◽  
Author(s):  
A. Kozak ◽  
J. Holejsovsky ◽  
P. Belobradek ◽  
L. Ostadalova ◽  
P. Chloupek
Keyword(s):  
General Condition ◽  
Disease Diagnosis ◽  
Locomotor Apparatus ◽  
Heart Insufficiency ◽  
Pelvic Injuries ◽  
Limb Injuries ◽  
The Difference ◽  
Spinal Contusion ◽  
Emergency Slaughter ◽  
Slaughtered Pigs

Immobility of pigs is a reason for emergency slaughter. The goal of this project was to determine the proportion of emergency slaughters due to immobility in pigs. In a selected pig slaughter facility, emergency slaughters were monitored in the period between 1997 and 2002 and the numbers of pigs slaughtered due to immobility reasons were monitored. The conclusion was that the proportion of sows slaughtered due to immobility reasons is high (31.3%) in comparison to other pigs (9.7%) and this difference was found to be statistically significant (P < 0.01).  The objective of the project was also to determine the causes of immobility in emergency slaughtered pigs. Veterinary carcass, meat and organs inspections revealed that locomotor apparatus diseases (pelvic injuries, spinal contusion injuries or injuries of limbs, hind limb paresis, limb injuries, joint and claw inflammations) were more frequent causes of emergency slaughters due to immobility in pigs than general and other conditions (cachexia and gastrointestinal tract disorders, ataxia, tetany, circulation disorders including heart insufficiency, post-delivery complications, selection and others). In sows, the number of immobile animals with the diagnosis of locomotor apparatus diseases was high (90.0%) in comparison to the general condition and other disease diagnoses (10.0%); the difference was found to be statistically significant (P < 0.01). In other pigs, the number of immobile animals with the locomotor apparatus disease diagnosis was particularly high (96.4%) in comparison to the general condition and other disease diagnoses (3.6%); the difference was found to be statistically significant (P < 0.01). The results evidence that in sows as well as in other pigs, immobility necessitating emergency slaughters is due to unsuitable handling resulting in injuries and pareses of the locomotor apparatus rather than insufficient care leading to general conditions and other diseases.

Intraoperative Imaging in Pelvic Surgery

2018 ◽  
Vol 157 (04) ◽  
pp. 367-377 ◽  
Author(s):  
Holger Keil ◽  
Sara Aytac ◽  
Paul Alfred Grützner ◽  
Jochen Franke
Keyword(s):  
General Condition ◽  
Pelvic Ring ◽  
Intraoperative Imaging ◽  
Pelvic Surgery ◽  
Acetabular Fractures ◽  
Posterior Pelvic Ring ◽  
Data Set ◽  
Intraoperative 3D Imaging ◽  
Pelvic Injuries ◽  
Preoperative Ct

AbstractPelvic fractures may range from highly severe, life-threatening injuries to less acute clinical entities. There are several sub-entities that are summed up as pelvic injuries. Anatomically, there are fractures of the anterior or posterior pelvic ring. Apart from these, there are fractures of the acetabulum that make up about one fifth of all pelvic injuries. The indication for surgical treatment of pelvic ring injuries depends on the type of injury, involvement of anterior and/or posterior elements of the pelvic ring, demands and the general condition of the patient. In acetabular fractures, indications depend on the dislocation of the fracture and of course also the needs of the patient and his general condition. An intraarticular step-off of more than 2 mm is usually considered as an indication for open reduction and osteosynthesis. Usually in all these injuries, a preoperative CT scan is mandatory to allow precise planning of the operative approach and technique. Intraoperatively, the surgeon should be familiar with the acquisition of the 2D standard views, including 2D imaging of the pelvic ring and the acetabulum. These consist of the anteroposterior view for both pelvic ring and acetabular osteosyntheses. For further assessment of pelvic ring treatments, inlet and outlet views are achievable by angulating the C-arm cranially and caudally. To assess aspects of the anterior and posterior column of the acetabulum, iliac oblique views are used. Here, the C-arm is rotated laterally. As evaluation of 2D views can be limited due to anatomy and superposing structures, intraoperative 3D imaging has become common in the last decade. Special C-arms allow the automatic acquisition of large numbers of projections and create CT-like views of the central volume. Although this method has significantly widened the possibilities of intraoperative imaging, some issues remain. Depending on the amount of implants placed in the imaging field, assessment can be seriously impaired due to artefacts caused by the implants. Intraoperative CT imaging promises enhanced image quality for artefacts and allows a considerably larger field of view. The use of radiation-free navigation facilitates implant placement in minimally invasive procedures like screw placement in the sacroiliacal joint or the acetabulum by visualisation of instruments and implants in a pre- or intraoperative 3D data set.

scholarly journals Model-based clustering for flow and mass cytometry data with clinical information

2020 ◽  
Vol 21 (S13) ◽  
Author(s):  
Ko Abe ◽  
Kodai Minoura ◽  
Yuka Maeda ◽  
Hiroyoshi Nishikawa ◽  
Teppei Shimamura
Keyword(s):  
Probabilistic Models ◽  
Clinical Information ◽  
Real Data ◽  
Disease Diagnosis ◽  
Cell Populations ◽  
Mass Cytometry ◽  
Allocation Model ◽  
Model Based Clustering ◽  
Bayesian Data Analysis ◽  
The Difference

Abstract Background High-dimensional flow cytometry and mass cytometry allow systemic-level characterization of more than 10 protein profiles at single-cell resolution and provide a much broader landscape in many biological applications, such as disease diagnosis and prediction of clinical outcome. When associating clinical information with cytometry data, traditional approaches require two distinct steps for identification of cell populations and statistical test to determine whether the difference between two population proportions is significant. These two-step approaches can lead to information loss and analysis bias. Results We propose a novel statistical framework, called LAMBDA (Latent Allocation Model with Bayesian Data Analysis), for simultaneous identification of unknown cell populations and discovery of associations between these populations and clinical information. LAMBDA uses specified probabilistic models designed for modeling the different distribution information for flow or mass cytometry data, respectively. We use a zero-inflated distribution for the mass cytometry data based the characteristics of the data. A simulation study confirms the usefulness of this model by evaluating the accuracy of the estimated parameters. We also demonstrate that LAMBDA can identify associations between cell populations and their clinical outcomes by analyzing real data. LAMBDA is implemented in R and is available from GitHub (https://github.com/abikoushi/lambda).

A Prior-Information-Based Combination Solution for Picking the Difference of Time-of-Flight in Ultrasound Computed Tomography

2020 ◽  
Vol 10 (3) ◽  
pp. 763-768 ◽  
Author(s):  
Xiaoyue Fang ◽  
Junjie Song ◽  
Kuolin Liu ◽  
Yun Wu ◽  
Qiude Zhang ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Sound Speed ◽  
Mean Squared Error ◽  
Median Filter ◽  
Time Of Flight ◽  
Disease Diagnosis ◽  
Phantom Experiment ◽  
Squared Error ◽  
Ultrasound Computed Tomography ◽  
The Difference

Sound speed imaging is one modal of ultrasound computed tomography (USCT) which is helpful for early breast disease diagnosis. One of the most critical processes of sound speed reconstruction is time-of-flight picking. As each of the traditional time-of-flight picking methods has shortcomings for real data, in this study, a practical priorinformation-based combination (PIBC) solution for picking the difference of time-of-flight between the reference data and the object data (DTOF) is proposed to enhance the reconstruction accuracy and uniformity. By using DTOF, some system bias will be effectively alleviated. Firstly, by analyzing the signal-amplitude, the "penetrating-through-the-object" and the "bypassing-the-object" signals are distinguished. Then for the "penetrating-throughthe-object" signals, based on the 'majority rule,' the consistency of DTOF picked by different methods are calculated as a basis to combine the advantages of different picking methods; for the "bypassing-the-object" signals, the DTOF closest to zero is chosen. Finally, the DTOFs are post-processed to suppress the noise by a median filter and to fix the deficiency of the system by an interpolation operator. The new solution is verified by in vitro breast phantom experiment conducted on the home-made USCT system "Lucid." The proposed PIBC solution can quantitatively decrease Root Mean Squared Error (RMSE) and Mean Squared Error (MSE) of DTOF picking and enhance the image quality of reconstructed sound speed images with higher accuracy and uniformity. This work is significant for ray-based sound speed reconstruction and can provide a fine initial solution for high-resolution wave-based reconstruction.

scholarly journals Proliferation Cycle Transcriptomic Signatures are Strongly associated With Gastric Cancer Patient Survival

2021 ◽  
Vol 9 ◽  
Author(s):  
Jianwen Hu ◽  
Yanpeng Yang ◽  
Yongchen Ma ◽  
Yingze Ning ◽  
Guowei Chen ◽  
...  
Keyword(s):  
Gene Expression ◽  
Gastric Cancer ◽  
Treatment Options ◽  
Disease Diagnosis ◽  
Gene Expression Omnibus ◽  
The Cancer Genome Atlas ◽  
Transcriptome Data ◽  
Genomic Changes ◽  
The Difference ◽  
Gastric Cancer Patients

Gastric cancer is one of the most heterogeneous tumors with multi-level molecular disturbances. Sustaining proliferative signaling and evading growth suppressors are two important hallmarks that enable the cancer cells to become tumorigenic and ultimately malignant, which enable tumor growth. Discovering and understanding the difference in tumor proliferation cycle phenotypes can be used to better classify tumors, and provide classification schemes for disease diagnosis and treatment options, which are more in line with the requirements of today’s precision medicine. We collected 691 eligible samples from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) database, combined with transcriptome data, to explore different heterogeneous proliferation cycle phenotypes, and further study the potential genomic changes that may lead to these different phenotypes in this study. Interestingly, two subtypes with different clinical and biological characteristics were identified through cluster analysis of gastric cancer transcriptome data. The repeatability of the classification was confirmed in an independent Gene Expression Omnibus validation cohort, and consistent phenotypes were observed. These two phenotypes showed different clinical outcomes, and tumor mutation burden. This classification helped us to better classify gastric cancer patients and provide targeted treatment based on specific transcriptome data.

scholarly journals Day Ward Glaucoma Patients Have Lower Depression Levels and Higher Glaucoma Knowledge Levels than Inpatients

2019 ◽  
Vol 2019 ◽  
pp. 1-7
Author(s):  
Huiming Xiao ◽  
Wenmin Huang ◽  
Xi Qin ◽  
Chengguo Zuo ◽  
Qiongman Yang ◽  
...  
Keyword(s):  
General Condition ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Case Group ◽  
Hospital Anxiety ◽  
Day Case ◽  
Knowledge Questionnaire ◽  
Inpatient Group ◽  
The Difference ◽  
Baseline Demographic

Importance. Psychological factors and glaucoma knowledge are closely related to the effects of glaucoma treatment. Background. Studies comparing anxiety and depression levels and glaucoma knowledge between glaucoma day-case patients and inpatients are limited. Design. Randomized clinical trial. Participants. Consecutive patients undergoing surgery were prospectively enrolled. Methods. Patients were randomized into the day-case group or the inpatient group. All of the patients underwent corresponding procedures for treatment, care, and education. All participants were asked to complete the General Condition Questionnaire, the Hospital Anxiety and Depression Scale (HADS), and the Gray Glaucoma Knowledge Questionnaire (GGKQ) at admission and the HADS and GGKQ at discharge. Main Outcome Measures. The scores for the General Condition Questionnaire, the HADS, and the GGKQ. Results. In total, 216 patients were enrolled in this study, including 119 day ward patients and 97 inpatients. There were no significant differences between the two groups in terms of their baseline demographic and clinical data (P>0.05). The baseline HADS-anxiety (HADS-A), HADS-depression (HADS-D), and GGKQ scores were similar in both groups (P>0.05). Before discharge, the difference in HADS-A scores between the two groups was not significant; however, the HADS-D scores of the day-case inpatients were significantly lower (α = 0.05, P<0.001), and the GGKQ scores of day-case inpatients were significantly higher than those of the inpatients before discharge (α = 0.05, P<0.001). Conclusions and Relevance. Day ward patients had lower levels of depression and higher levels of glaucoma knowledge.

scholarly journals Analysis of Differences in Tariff for Health Service Based on Sustability of Diagnosis on Admision and Summary Discharge Form with INA-CBGs Verification

2021 ◽  
Vol 1 (3) ◽  
pp. 82-86
Author(s):  
Oktamianiza Oktamianiza ◽  
Deni Maisa Putra ◽  
Yulfa Yulia ◽  
Agni Fahira ◽  
Afridon Afridon
Keyword(s):  
Health Insurance ◽  
Health Service ◽  
Medical Treatment ◽  
Fundamental Problem ◽  
Prospective Payment System ◽  
Disease Diagnosis ◽  
Discharge Summary ◽  
Payment System ◽  
Patient Diagnosis ◽  
The Difference

The implementation of the National Health Insurance starting in January 2014 made a change in the payment system from the Retrospective Paymant System to the Prospective Payment System with INA-CBG's rates. The difference in INA-CBG's rates and hospital rates is a fundamental problem so that hospitals must make efforts to achieve quality and cost control. the purpose of this research was to determine the Analysis of Differences in Tariff for Health Service Based on sustability of Diagnosis on the admision and discharge summary form (RM1) with INA-CBGs Verification at Hospital Dr. Reksodiwiryo Padang. The results of the study found that the accuracy of disease diagnosis and patient medical treatment was on the RM1 form (21.7%), on the INA-CBGs verification (56.5%). Differences in disease diagnosis and patient medical treatment on RM1 form with INA-CBGs verification (63.0%), and differences in health service fees based on accuracy of patient diagnosis and medical treatment on RM1 form with INA-CBGs verification (63.0%) . There is a significant relationship between the difference in the Tariff of health services with the accuracy of diagnosis on the RM1 form and the INA-CBGs verification which is quite large, due to the discrepancy in writing the diagnosis on RM1 with the INA-CBGs verification.

scholarly journals Emergent Stabilization of Pelvic Bones Fractures in Polytrauma

2014 ◽  
pp. 19-25 ◽  
Author(s):  
E. A. Litvina
Keyword(s):  
General Condition ◽  
Pelvic Ring ◽  
Damage Control ◽  
Pelvic Injury ◽  
Treatment Concept ◽  
Concomitant Injuries ◽  
Surgical Interventions ◽  
Acute Period ◽  
Pelvic Injuries ◽  
Modern Treatment

Principle aspects of the management of patients with concomitant pelvic injury and injuries of other localization from the standpoint of modern treatment concept Damage control are discussed. Special attention are paid to the techniques for pelvic ring fixation, arrest of intrapelvic hemorrhage, sequence of surgical interventions depending on the pattern of concomitant injuries. The necessity of emergent pelvic injuries fixation with external devices as well as the fractures of other localization in the acute period until stabilization of patient’s general condition is substantiated

scholarly journals Emergent Stabilization of Pelvic Bones Fractures in Polytrauma

2014 ◽  
Vol 21 (1) ◽  
pp. 19-25
Author(s):  
E. A Litvina
Keyword(s):  
General Condition ◽  
Pelvic Ring ◽  
Damage Control ◽  
Pelvic Injury ◽  
Treatment Concept ◽  
Concomitant Injuries ◽  
Surgical Interventions ◽  
Acute Period ◽  
Pelvic Injuries ◽  
Modern Treatment

Principle aspects of the management of patients with concomitant pelvic injury and injuries of other localization from the standpoint of modern treatment concept Damage control are discussed. Special attention are paid to the techniques for pelvic ring fixation, arrest of intrapelvic hemorrhage, sequence of surgical interventions depending on the pattern of concomitant injuries. The necessity of emergent pelvic injuries fixation with external devices as well as the fractures of other localization in the acute period until stabilization of patient’s general condition is substantiated

Prediction of the Longitudinal Arch Angle During Running for Various Foot Strike Patterns Using a Static Longitudinal Arch Angle Measurement

2020 ◽  
Vol 110 (3) ◽  
Author(s):  
Norio Tsujimoto
Keyword(s):  
Metatarsal Head ◽  
Angle Measurement ◽  
Medial Malleolus ◽  
Navicular Bone ◽  
First Metatarsal ◽  
Longitudinal Arch ◽  
Contact Patterns ◽  
Limb Injuries ◽  
Foot Strike ◽  
The Difference

Background The medial longitudinal arch angle (LAA) of the foot has been used as an index of high and low arches. The LAA during the support phase of running (LAArun), which may be related to lower-limb injuries, is commonly predicted from the LAA at standing (LAAstand). However, it is not known whether this prediction is valid for all of the foot contact patterns. The purpose of this study was to verify whether prediction of the LAArun from the LAAstand is valid for different foot strike patterns. Methods The 26 participants were divided into a rearfoot strike group (n = 15) and a nonrearfoot strike group (n = 11). The LAA was obtained by measuring the angle formed between the line from the navicular bone to the medial malleolus and the line from the navicular bone to the first metatarsal head. The LAAstand and the minimum value of the LAArun, when the arch is most collapsed, were measured using a motion capture system. Results There were no significant differences in the LAAstand, the LAArun, and the difference (LAAstand – LAArun) between the two groups. In both groups, a very strong and significant correlation was found between the LAAstand and the LAArun. Furthermore, a nearly identical equation for predicting the LAArun from the LAAstand was derived for the two groups. Conclusions The LAArun can be predicted from the LAAstand for any foot strike pattern with almost the same equation.

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