scholarly journals Comparative efficacy of various therapeutic protocols in the treatment of pyometra in bitches

2013 ◽  
Vol 58 (No. 5) ◽  
pp. 271-276 ◽  
Author(s):  
B. Jena ◽  
KS Rao ◽  
KCS Reddy ◽  
KBP Raghavender

This study was undertaken on canine pyometra and consisted of 28 bitches of different breeds with known breeding history and open type of pyometra. The diagnosis of pyometra was made by correlating the history and clinical signs with the findings of abdominal palpation, radiography and ultrasonography. The physiological, haematological and biochemical parameters were evaluated before and at the end of therapy. The clinical cases were divided randomly into four different groups with each group consisting of seven bitches. One untreated control group in which bitches were given only supportive therapies was included. The bitches in the other three groups were treated using natural PGF<sub>2</sub>&alpha; or synthetic PGF<sub>2</sub>&alpha; or a combination of a dopamine agonist prolactin-inhibiting drug, i.e., cabergoline and lower dose of synthetic PGF<sub>2</sub>&alpha; (Cloprostenol) along with supportive therapies. Treatment of canine pyometra by the use of different drugs was found to be successful. Though a lower dose of cloprostenol was effective in treating pyometra, it is not recommended due to high rates of recurrence and lower conception rates. Treatment of canine pyometra using a combination of a dopamine agonist prolactin-inhibiting drug (Cabergoline) and a lower dose of synthetic PGF<sub>2</sub>&alpha; (Cloprostenol) was found to be the most effective method among the three therapeutic protocols used in the present study. &nbsp;

Ultrasound ◽  
2020 ◽  
Vol 28 (3) ◽  
pp. 174-179
Author(s):  
Sonay Aydin ◽  
Berna Ucan

Introduction Acute appendicitis is the most common reason for emergency abdominal surgery in the pediatric population. Ultrasound (US) is a widely used modality to diagnose acute appendicitis. The aim of this study was to evaluate the effectiveness of portal vein diameter and flow velocity in acute appendicitis diagnosis. Methods Portal vein diameter and flow velocity were measured in children who were referred to radiology with a clinical diagnosis of acute appendicitis. The largest appendix diameter and leukocyte count of the patients were recorded. A control group was created which consisted of healthy children, and their portal vein diameter and flow velocities were also measured. Results The median age of the population was 10 years (range, 3–17 years). Mean portal vein diameter was 7.53 ± 1.55 mm in the control group, 7.92 ± 1.88 mm in the other diagnosis group, and 8.76 ± 1.91 mm in the acute appendicitis group. Mean portal vein diameter was significantly higher in the acute appendicitis group (p = 0.001). Median portal vein flow velocity was 17 cm/s (10–29 cm/s) in the control group, 18.3 cm/s (8–27 cm/s) in the other diagnosis group, and 20.5 cm/s in the acute appendicitis group. Median portal vein flow velocity was significantly higher in the acute appendicitis group (p = 0.00). Conclusion Detecting an increase in portal vein diameter and/or flow velocity in equivocal cases may support other clinical signs associated with acute appendicitis. Portal vein diameter and flow velocity can serve as additional diagnostic markers in acute appendicitis cases.


Biologia ◽  
2011 ◽  
Vol 66 (1) ◽  
Author(s):  
Ján Praslička ◽  
Janka Schlarmannová ◽  
Barbora Matejovičová ◽  
Ján Tancík

AbstractThe effectiveness of the predatory mite Typhlodromus pyri and of an application of Polysulphide-Ca was compared during 2006–2008. The experiment showed differences in infestation levels of pear leaves caused by Eriophyes pyri. The highest percentage of leaves with symptoms was found in untreated control group (⊘ 20.9%); the lowest percentage was found in plots treated with T. pyri (⊘ 3.7%); and a slightly higher percentage was found in plots treated with Polysulphide-Ca (⊘ 8.6%). During 2006–2008 the percentage of leaves with symptoms was approximately the same only in the untreated control plots (from 20.3% to 21.5%). The percentage of leaves with characteristic symptoms in plots treated with T. pyri decreased from 5.5% in 2006 to 4.3% in 2007, and to 1.3% in 2008. On the other hand, the percentage of leaves with symptoms in plots treated with Polysulphide-Ca increased from 5.5% in 2006 to 8.5% in 2007, and to 11.8% in 2008. The intensity of symptoms on infested leaves was also different depending on treatments and years. The average biological activity was 82.4% in plots receiving releases of T. pyri and 58.8% in plots treated with Polysulphide-Ca.


2019 ◽  
Vol 10 (2) ◽  
pp. 133
Author(s):  
Gaymary George Bakari ◽  
Robert Arsen Max ◽  
Shedrack Reuben Kitimu ◽  
Shaabani Mshamu ◽  
Benigni Alfred Temba ◽  
...  

The study was conducted to assess the effects of sweet potato leaves, roselle calyces and beetroot tubers on body weight, selected hematological and biochemical parameters in broiler chickens. Eighty four (84) broiler chickens aged four weeks were randomly assigned into six groups of 14 chickens each. The first group (G0) remained as untreated control while the other groups were the treated groups which received 25% of ground sweet potato leaves (G1), rosella calyces (G2), beetroot tubers (G3) and their mixtures (G4 and G5) for 28 days. Following inclusion of these different vegetables, blood samples were collected and analyzed for selected hematological and biochemical parameters on day 0, 7, 14, 21 and 28. Results showed that consumption of the three vegetables caused significant decreases (p < 0.05) in body weight, serum glucose and cholesterol. On the other hand, hemoglobin concentration, packed cell volume (PCV) and total white blood cell (WBC) counts were shown to increase significantly (p < 0.05) compared to the control group. It is concluded that the hypoglycemic and hypocholesteremic effects in chickens following consumption of the three vegetables together with their positive effects on PCV and WBC counts are important qualities which can be utilized in the management of conditions such as obesity, diabetes mellitus, hyperlipidemia and cardiovascular diseases (atherosclerosis and coronary disease) in humans. Further studies in other animals are recommended.


Foods ◽  
2020 ◽  
Vol 9 (6) ◽  
pp. 719
Author(s):  
Jonas Roberto Velasco-Chong ◽  
Oscar Herrera-Calderón ◽  
Juan Pedro Rojas-Armas ◽  
Renán Dilton Hañari-Quispe ◽  
Linder Figueroa-Salvador ◽  
...  

Potato tocosh is a naturally processed potato for nutritional and curative purposes from traditional Peruvian medicine. The aim of this study was to investigate the acute and sub-acute toxicity of tocosh flour (TF). For sub-acute toxicity, TF was administered orally to rats daily once a day for 28 days at doses of 1000 mg/kg body weight (BW). Animals were observed for general behaviors, mortality, body weight variations, and histological analysis. At the end of treatment, relative organ weights, histopathology, hematological and biochemical parameters were analyzed. For acute toxicity, TF was administered orally to mice at doses of 2000 and 5000 mg/kg BW at a single dose in both sexes. Body weight, mortality, and clinical signs were observed for 14 days after treatment. The results of acute toxicity showed that the median lethal dose (LD50) value of TF is higher than 2000 g/kg BW but less than 5000 mg/Kg BW in mice. Death and toxicological symptoms were not found during the treatment. For sub-acute toxicity, we found that no-observed-adverse-effect levels (NOAEL) of TF in rats up to 1000 g/kg BW. There were statistically significant differences in body weight, and relative organ weight in the stomach and brain. No differences in hematological and biochemical parameters were observed when compared with the control group. For sub-acute toxicity, histopathological studies revealed minor abnormalities in liver and kidney tissues at doses of 5000 mg/Kg. Based on these results, TF is a traditional Peruvian medicine with high safety at up to 1000 mg/kg BW for 28 days in rats.


2017 ◽  
Vol 9 (2) ◽  
pp. 48
Author(s):  
Samaneh Hedayati Manesh ◽  
Azam Alikhademi

This study was an attempt to examine the impact of Neurofeedback on clinical signs of Children that have attention deficit disorder and hyperactivity. The participants of this study 24 boys (6-11) that afflicted to ADHD. The participants of the study randomly divided into two groups and were selected to participate in the study. The experimental group received the Neurofeedback treatment (8 weeks, three sessions in a week). The control group, on the other hand was placed in a wait list. After treatment, CBCL, IVA, QEEG were administered between two groups. The analysis of data revealed that Nero feedback has a significant impact on ADHD children. Moreover, Neurofeedback treatment leads to improve attention deficit disorder and decrease impulsivity in ADHD children.


1995 ◽  
Vol 73 (2) ◽  
pp. 235-243 ◽  
Author(s):  
Cynthia Lokker ◽  
Paul B. Cavers

Individual flowering ramets in a large riverbank stand of Saponaria officinalis, bouncingbet, were subjected to three damage treatments at anthesis: removal of most flowers, removal of all leaves, and bending of the stem just below the inflorescence. All seeds were collected from ripened capsules of treated plants as well as from a group shaded by a canopy of Convolvulus sepium and from an untreated control group. Seeds from the defloration treatment were significantly heavier than those from the other treatments. In the control, bent stem, and shaded treatments the seed masses were distributed in a bimodal manner, with most seeds forming a normal distribution around a midpoint of 1.5–1.7 mg and a cohort of heavy seeds having a mean mass of 2.5 mg. This heavy cohort (mode) was missing from the defoliation treatment. Of the total variation in seed mass, 36% was among individuals, 54% was among inflorescences within individuals, and only 10% was within inflorescences. This suggests that resources are allocated differentially between capsules at different positions on the inflorescence but almost uniformly within the individual capsule. Key words: defoliation, defloration, bouncingbet, seed production, Saponaria officinalis.


Parasitology ◽  
2021 ◽  
pp. 1-6
Author(s):  
Amal Farahat Allam ◽  
Reham Ahmed Mostafa ◽  
Wael Lotfy ◽  
Hoda Fahmy Farag ◽  
Naglaa Fathi ◽  
...  

Abstract The present work aimed at studying the efficacy of mebendazole (MBZ) compared to artemisinin (ART) for the treatment of trichinellosis at various phases of infection. Seventy Swiss albino mice were orally infected by 300 Trichinella spiralis (T. spiralis) larvae. Mice were divided into infected untreated control group and infected groups treated with 50 mg kg−1 MBZ and 300 mg kg−1 ART for three and five consecutive days, respectively, at the enteral phase [2–4 days post infection (PI)], invasive phase (10–12 days PI) and encapsulated phase (28–30 days PI). All mice were sacrificed 35–42 days PI. MBZ and ART revealed a significant decrease in mean larval counts and increase of larval per cent reduction (LR %) when treatment was initiated during the enteral phase compared to the other phases. MBZ showed significantly higher LR % (99.7, 83.95 and 89.65%) than ART (80.58, 67.0 and 79.2%) when administered at the three infection phases. Histopathological study showed a decrease in the number of encysted larvae, their surrounding cellular infiltrates and increased regenerative muscles in all treated mice. In conclusion, ART possesses a substantial anthelmintic activity against T. spiralis infection in mice both at the enteral and encapsulated phases, yet, significantly lower than MBZ.


Author(s):  
P. Sarkar S. Basu ◽  
K. Ray A. Saren ◽  
D. Mandal S. Das ◽  
C. K. Ghosh

Pyometra is one of the most common diseases in intact bitches. The aim of the present communication was to evaluate the effectiveness of medical treatment for the close pyometra in a bitch. The diagnosis of pyometra was made by correlating the history and clinical signs with the findings of abdominal palpation and ultrasonography. The physiological, haematological and biochemical parameters were evaluated before and after treatment. Treatment of canine pyometra using a combination of progesterone receptor blocker (Mifepristone), anti-prolactin (Cabergoline) along with supportive therapy showed very efficacious alternative option over traditional ovario-hysterectomy (OHE) or which are critical for operative procedure.


1970 ◽  
Vol 6 (1) ◽  
pp. 115-119 ◽  
Author(s):  
MR Amin ◽  
M Mostofa ◽  
MA Awal ◽  
MA Sultana

The experiment was conducted in the Department of Pharmacology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh, for a period of 28 days to study the effects of garlic (Allium sativum, Linn., @100mg/kg bwt.), turmeric (Curcuma longa, Linn., @100mg/kg bwt.)  and betel leaf (Piper betle, Linn., @100mg/kg bwt.) against natural gastrointestinal nematodes in cattle. The effects of garlic, turmeric and betel leaf on some hematological parameters (TEC, Hb, PCV and TLC), biochemical parameters (ALT and AST) and clinical parameter (body weight) were also observed. Twenty four (24) naturally parasitized cattle of BAU Dairy Farm, Mymensingh were randomly divided into four groups, each consisting of six (6) cattle. Water extract of bulbs of garlic were administered orally to the cattle of group A. Cattle of group B received orally water extract of rhizome of turmeric. Cattle of group C were treated orally with leaves of betel leaf. Cattle of group D was kept as infected control group. Fecal samples, body weight, hematological and biochemical parameters were examined before treatment and on 3rd, 10th, 17th and 28th day. A significant (p < 0.01) reduction of EPG count was found following administration of garlic (20.41-40.81%), turmeric (6.09-19.27%) and betel leaf (2.91-9.8%) in cattle. The EPG count of the control group (D) were significantly (p < 0.01) increased up to the last day of experimental period. After treatment with garlic and turmeric total erythrocyte count (TEC), hemoglobin (Hb) content and packed cell volume (PCV) were gradually increased significantly (p < 0.01 and p < 0.05) in cattle. Conversely, the total leukocyte count (TLC) were decreased significantly (p < 0.01 and p < 0.05) in treated cattle. On the other hand, TEC, Hb content and PCV were gradually increased significantly (p < 0.01 and p < 0.05) on day 3 and day 10 in betel leaf treated cattle but decreased on 17th and 28th day. Conversely, the total leukocyte count (TLC) were decreased significantly (p < 0.01 and p < 0.05) on day 3 and day 10 in betel leaf treated cattle but increased significantly (p < 0.01) on 17th and 28th day. The alanine aminotransferase (ALT) and aspartate aminotransferase (AST) level were not significantly changed in the cattle. The body weight was increased significantly (p < 0.01 and p < 0.05) in garlic, turmeric and betel leaf treated cattle. On the other hand, body weight was decreased in untreated control group. The present study reveals that water extracts of garlic were moderately effective and turmeric and betel leaf were relatively less effective against gastrointestinal nematodes in cattle. Key words: Nematodes, garlic, turmeric, betel, leaf, cattle DOI = 10.3329/bjvm.v6i1.1349 Bangl. J. Vet. Med. (2008). 6 (1): 115-119


Author(s):  
L.J. Fourie ◽  
D. Stanneck ◽  
I.G. Horak

The efficacy of 2 sets of collars (Kiltix(R) Collar, Bayer AG), containing different plasticisers and impregnated with the acaricides flumethrin (2.25 %) and propoxur (10 %), was compared against adult Rhipicephalus sanguineus on experimentally infested, kennelled dogs. Thirty individually penned dogs were infested with 25 male and 25 female, unfed R. sanguineus. On the following day they were allocated to 3 groups of 10 dogs each on the magnitude of their tick burdens. Two days after infestation, medicated collars containing 1 of the plasticisers were fitted to 10 of the dogs and similar collars containing the other plasticiser were fitted to 10 others. The remaining 10 dogs were the untreated controls. Seven and 28 days after having fitted the collars, all dogs were re-infested with 50 unfed adult ticks of both sexes, and again at approximately 28-day intervals up to the 5th month, and then at approximately 14-day intervals during the 6th month. Efficacy was determined by comparing the mean number of live, attached ticks on the untreated control group with those on the collared dogs 2 days after each re-infestation. Immediate efficacy of the collars (Day +2) was > 95 %, and residual efficacy was > 98% up to and including Day +114, and > 93 % up to Day +170 on both groups of collared dogs. The mean tick counts on the 2 groups of collared dogs did not differ significantly (P < 0.0001) for any of the assessment days.


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