scholarly journals Non-communicating small intestinal duplication in a dog: a case report

2017 ◽  
Vol 62 (No. 9) ◽  
pp. 516-521 ◽  
Author(s):  
TS Hwang ◽  
DI Jung ◽  
JH Kim ◽  
SC Yeon ◽  
HC Lee
Keyword(s):  
Physical Examination ◽  
Complete Blood Count ◽  
Postoperative Recovery ◽  
Histopathological Diagnosis ◽  
Intestinal Segment ◽  
Radiographic Images ◽  
Intestinal Duplication ◽  
National University ◽  
Enteric Duplication ◽  
Small Intestinal

Enteric duplication is rare in dogs. Here, we report the rarest form of duplication in which two segments are parallel and share a wall for most of their lengths. A nine-year-old spayed female Yorkshire terrier was referred to the Veterinary Medical Teaching Hospital at Gyeongsang National University due to anorexia and diarrhoea. Physical examination, haematological examination, radiography, and ultrasonography were performed. On physical examination, dry, pale mucous membrane was identified. Moderate anaemia with decreased packed cell volume was detected in complete blood count. Serum urea nitrogen and creatinine levels were mildly increased. Radiographic images revealed no significant findings. On ultrasonographic examination, a multi-layered appearance of a focal small intestinal segment was identified in the left mid abdomen. Following the lesion, it was divided into two small intestinal segments. Based on imaging findings, intussusceptions or enteric duplication were suspected. To resect the abnormal small intestinal segment, enterectomy was performed. Follow-up was not performed because the patient expired during the postoperative recovery time. The histopathological diagnosis was non-communicating small intestinal duplication. Non-communicating intestinal duplication is related to embryologic abnormalities and is usually concurrent with other anomalies such as vertebral malformations and urogenital duplications. However, this case had no other anomalies associated with the malformation of the intestine.

scholarly journals Pseudomyxoma Peritonei Originating from an Intestinal Duplication

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Julie Lemahieu ◽  
André D'Hoore ◽  
Stijn Deloose ◽  
Raf Sciot ◽  
Philippe Moerman
Keyword(s):  
Pseudomyxoma Peritonei ◽  
Villous Adenoma ◽  
Histopathological Diagnosis ◽  
Low Grade ◽  
Intestinal Duplication ◽  
Peritoneal Implants ◽  
Disseminated Peritoneal Adenomucinosis ◽  
Uncommon Condition ◽  
Small Intestinal ◽  
Upper Abdominal

Alimentary tract duplications are rare congenital anomalies. They most often become symptomatic in childhood and rarely undergo malignant transformation. Pseudomyxoma peritonei (PMP) is an equally uncommon condition, most frequently originating from a primary appendiceal mucinous neoplasm. We report an extremely unusual case of PMP arising from an intestinal duplication. A 67-year-old woman presented with vague upper abdominal pain, and, unexpectedly, explorative laparoscopy revealed diffuse jelly-like peritoneal implants. The histopathological diagnosis of a low-grade PMP or “disseminated peritoneal adenomucinosis” was made. At that moment, no primary tumor was found. During later surgery, a cystic lesion located in the mesentery of the small bowel could be resected. Histologically, the cyst wall clearly showed the concentric layering of a normal bowel wall. The mucosa, however, displayed a diffuse low-grade villous adenoma. We concluded that this histological picture was most consistent with a small intestinal duplication, containing a low-grade villous adenoma. The adenoma caused a mucocele, which subsequently leaked or ruptured, giving rise to noninvasive mucinous peritoneal implants or low-grade PMP, also known as “disseminated peritoneal adenomucinosis” (DPAM).

Development of a portocaval shunt using a small intestinal segment in rats

Microsurgery ◽  
2010 ◽  
Vol 30 (4) ◽  
pp. 302-306 ◽  
Author(s):  
Toshiyuki Hata ◽  
Junji Iwasaki ◽  
Shuji Hishikawa ◽  
Yasuhiro Fujimoto ◽  
Shinji Uemoto ◽  
...  
Keyword(s):  
Portocaval Shunt ◽  
Intestinal Segment ◽  
Small Intestinal

scholarly journals Tubular subtotal form of the small intestinal doublication

2020 ◽  
Vol 10 (1) ◽  
pp. 75-80
Author(s):  
Andrei V. Pisklakov ◽  
Denis A. Fedorov ◽  
Sergey V. Moroz ◽  
Vyacheslav I. Ponomarev ◽  
Anatoly V. Lysov ◽  
...  
Keyword(s):  
Gastric Mucosa ◽  
Mucous Membrane ◽  
Complete Removal ◽  
Proximal Part ◽  
Pancreatic Tissue ◽  
Intestinal Duplication ◽  
Common Wall ◽  
Rare Malformation ◽  
Small Intestinal ◽  
Mini Laparotomy

Duplication of the gastrointestinal tract is a relatively rare malformation. The incidence is approximately 1 in 10 000 live births with the small intestinal duplication in most cases. Malformations with a long duplication part are considered technically complex. A successfully treated clinical case of the subtotal small intestinal duplication in a child is presented in the article. The mid-median mini-laparotomy was performed and a subtotal 1 meter length small intestinal duplication was revealed (from the Treitzs ligament to the ileum in 50 cm from the ileocolic valve). The proximal part of the intestinal duplication and its mucous membrane of the distal part with the common wall were completely removed. Histological examination found ectopia of the gastric mucosa and pancreatic tissue. Surgical treatment of this malformation is aimed at the complete removal of the duplication part due to possible ectopia of the gastric mucosa or pancreatic tissue. If the resection of an entire part of the intestinal duplication is technically impossible, the mucous membrane can be removed.

scholarly journals Anastomosing Haemangioma of the Kidney Involving a Segmental Branch of the Renal Vein

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Ayodeji Oluwarotimi Omiyale ◽  
Anurag Golash ◽  
Amandeep Mann ◽  
Dimitris Kyriakidis ◽  
Karthik Kalyanasundaram
Keyword(s):  
Renal Vein ◽  
Renal Mass ◽  
Incidental Finding ◽  
Postoperative Recovery ◽  
Tumour Recurrence ◽  
Laparoscopic Nephrectomy ◽  
Genitourinary Tract ◽  
Histopathological Diagnosis ◽  
Vascular Tumour ◽  
Capillary Haemangioma

Anastomosing variant of capillary haemangioma is a rare and recently described vascular tumour with a proclivity for the genitourinary tract. Here we present the case of a 64-year-old man with incidental finding of 3.4 cm renal mass on CT who had laparoscopic nephrectomy with a good postoperative recovery. Histopathological diagnosis of anastomosing haemangioma of the kidney was made and the patient was followed up for 10 months without evidence of tumour recurrence.

scholarly journals SUBCORNEAL PUSTULAR DERMATOSIS IN A 47-YEAR-OLD WOMAN

2015 ◽  
Vol 7 (3) ◽  
Author(s):  
Niken Ernaningtyas ◽  
Nana N. Jayadi ◽  
Herry E. J. Pandaleke
Keyword(s):  
Physical Examination ◽  
Complete Blood Count ◽  
Histopathological Examination ◽  
The Body ◽  
Unknown Etiology ◽  
Inflammatory Infiltration ◽  
Gram Staining ◽  
Subcorneal Pustular Dermatosis ◽  
Erythematous Skin ◽  
Laboratory Examinations

Abstrak: Subcorneal pustular dermatosis (SPD) adalah penyakit inflamasi kulit yang jarang dan kronik-rekuren. Penyakit ini umumnya didapatkan pada wanita usia diatas 40 tahun dengan etiologi belum diketahui. Gambaran klinis yang khas berupa pustul atau vesikel yang dengan cepat berubah menjadi pustul di atas dasar kulit eritematosa, menyebar periferal, central healing, dan menyembuh meninggalkan area eritematosa berbentuk polisiklik disertai munculnya lesi baru. Lesi mengenai area intertriginosa, batang tubuh, dan daerah fleksural ekstremitas. Kami melaporkan kasus seorang perempuan usia 47 tahun dengan keluhan lepuh di hampir seluruh tubuh sejak setahun lalu. Lepuh mudah pecah dan meninggalkan erosi. Status dermatologis menunjukkan generalisata makula eritematosa et hiperpigmentasi, multipel, diskret, ukuran lentikular-plakat; vesikel multipel dan pustul di atasnya; dan pustul yang pecah dengan erosi dan krusta. Pada pasien dilakukan anamnesis, pemeriksaan laboratorium, serta biopsi kulit. Pemeriksaan Gram lepuh menunjukkan hanya terdapat leukosit PMN. Laboratorium darah lengkap normal, hitung eosinofil 1,9%, hitung limfosit 24,3%, LED 70 mm/jam, dan IgE total 831.000 IU/mL. Pemeriksaan histopatologik menunjukkan spongiosis, lepuh subkorneal berisi fibrin, neutrofil, sedikit eosinofil di epidermis. Pada dermis tampak superficial perivascular inflammatory infiltration (neutrofil, limfosit, sedikit eosinofil). Pada kasus ini, diagnosis ditegakkan berdasarkan anamnesis, pemeriksaan fisik, dan pemeriksaan histopatologik yang khas untuk SPD.Kata kunci: subcorneal pustular dermatosis, pemeriksaan histopatologikAbstract: Subcorneal pustular dermatosis (SPD) is a pustular eruption which is rare, chronic, and recurrent. This condition is commonly found in women over the age of 40 years with unknown etiology. It is characterized with symmetrical pustules/vesicles that quickly develop to pustules on erythematous skin with peripherally spreading. The pustules undergo central healing leaving polycyclic erythematous areas in which new pustules arise. The lesions typically involve the intertriginous areas, trunks, and flexor of limbs. We reported a case of a 47-year-old woman with blisters and pustules all of the body surface since a year ago. The blisters ruptured easily and became erosions. The dermatological status indicated generalized erythematous hyperpigmented macules which were multiple, discrete, lenticular-plaques in size, multiple vesicles with pustules on them, and ruptured pustules leaving erosions as well as crusted areas. Anamnesis, physical examination, laboratory examinations, and a skin biopsy were performed. The Gram staining of the blister showed only PMN leukocytes. There were a normal complete blood count, eosinophil count 1.9%, lymphocyte count 24.3%, elevated ESR 70 mm/hour, and the total IgE 831.000 IU/mL. The histopathological examination indicated spongiosis, subcorneal blister consisting of fibrin, neutrophils, and few eosinophils in the epidermis. The dermis revealed superficial perivascular inflammatory infiltration (neutrophils, lymphocytes, some eosinophils). These findings were typical for SPD. Conclusion: This case was diagnosed as subcorneal pustular dermatosis based on anamnesis, physical examination, and a histopathological examination.Keywords: subcorneal pustular dermatosis, histopathological examination

Clinical characteristics and causes of chest pain in 380 children referred to a paediatric cardiology unit

2012 ◽  
Vol 23 (3) ◽  
pp. 361-367 ◽  
Author(s):  
Ahmet Sert ◽  
Ebru Aypar ◽  
Dursun Odabas ◽  
Cem Gokcen
Keyword(s):  
Chest Pain ◽  
Physical Examination ◽  
Clinical Characteristics ◽  
Complete Blood Count ◽  
Exercise Stress ◽  
Child Psychiatrist ◽  
Stress Tests ◽  
Paediatric Cardiology ◽  
Premature Cardiovascular Disease ◽  
History Of

AbstractBackgroundChest pain is a common presenting complaint to paediatrics, paediatric cardiology, and paediatric emergency departments. In this study, we prospectively evaluated clinical characteristics and causes of chest pain in children referred to our paediatric cardiology unit.MethodsA total of 380 children were included. Associated symptoms and past and family histories were evaluated. All patients underwent physical examination. The following studies were performed: complete blood count in all patients; fasting lipid profiles in overweight and obese children and children with a family history of premature cardiovascular disease; and electrocardiogram, chest X-ray, and echocardiogram in all patients. If necessary, 24-hour electrocardiogram monitoring or exercise stress tests were performed. Patients with a history of positive psychological findings were evaluated by a child psychiatrist.ResultsThe most common causes of chest pain were musculoskeletal disorders (37.1%), idiopathic chest pain (29.2%), and miscellaneous disorders, for example precordial catch syndrome (15%), respectively. Only 1 of 380 (0.3%) patients had chest pain due to a cardiac disorder. Electrocardiograms were abnormal in 4 of 380 (1.1%) patients. A total of 9 of 380 patients (2.3%) had dyslipidaemia.ConclusionsAlthough a paediatric cardiology referral may provide reassurance to the primary care and emergency department physicians, our results show that cardiac aetiologies for paediatric chest pain are very rare. We think that many patients in our study were adequately evaluated only by careful history, and physical examination. Therefore, we suggest that it may not be necessary to use echocardiogram in the routine evaluation of children with chest pain.

scholarly journals Intestinal Hypoxia-inducible Factor-2α (HIF-2α) Is Critical for Efficient Erythropoiesis

2011 ◽  
Vol 286 (22) ◽  
pp. 19533-19540 ◽  
Author(s):  
Erik R. Anderson ◽  
Xiang Xue ◽  
Yatrik M. Shah
Keyword(s):  
Serum Iron ◽  
Essential Role ◽  
Blood Count ◽  
Iron Absorption ◽  
Complete Blood Count ◽  
Hypoxia Inducible Factor ◽  
Wild Type ◽  
Reverse Transcription Pcr ◽  
Small Intestinal

Erythropoiesis is a coordinated process by which RBCs are produced. Erythropoietin, a kidney-derived hormone, and iron are critical for the production of oxygen-carrying mature RBCs. To meet the high demands of iron during erythropoiesis, small intestinal iron absorption is increased through an undefined mechanism. In this study, erythropoietic induction of iron absorption was further investigated. Hypoxia-inducible factor-2α (HIF-2α) signaling was activated in the small intestine during erythropoiesis. Genetic disruption of HIF-2α in the intestine abolished the increase in iron absorption genes as assessed by quantitative real-time reverse transcription-PCR and Western blot analyses. Moreover, the increase in serum iron following induction of erythropoiesis was entirely dependent on intestinal HIF-2α expression. Complete blood count analysis demonstrated that disruption of intestinal HIF-2α inhibited efficient erythropoiesis; mice disrupted for HIF-2α demonstrated lower hematocrit, RBCs, and Hb compared with wild-type mice. These data further cement the essential role of HIF-2α in regulating iron absorption and also demonstrate that hypoxia sensing in the intestine, as well as in the kidney, is essential for regulation of erythropoiesis by HIF-2α.

scholarly journals Ossifying fibroma – diagnosis, treatment, and follow-up: case report and literature review

2017 ◽  
Vol 32 (1) ◽  
pp. 54
Author(s):  
Fernando De Oliveira Andriola ◽  
Leonardo Matos Santolim Zanettini ◽  
Bernardo Ottoni Braga Barreiro ◽  
Valéria Rodrigues Saraiva ◽  
Fábio Luiz Dal Moro Maito ◽  
...  
Keyword(s):  
Bone Repair ◽  
Panoramic Radiograph ◽  
Ossifying Fibroma ◽  
Surgical Removal ◽  
Histopathological Diagnosis ◽  
Postoperative Rehabilitation ◽  
Radiographic Images ◽  
Effective Option ◽  
History Of

OBJECTIVE: This article presents a case of ossifying fibroma (OF), including its diagnosis, treatment, and 15-month clinical and radiographic follow-up as well as a review of the literature about this pathology.CASE REPORT: A routine panoramic radiograph of a 27-year-old, systemically healthy, white woman revealed a radiolucent lesion with well-defined sclerotic margins of approximately 3 × 2 cm in the mandible. The histopathological diagnosis revealed it was an OF. Lower Right Canine and Lower Right First Premolar teeth were endodontically treated for later surgical removal of the tumor. There was no history of trauma in the region.CONCLUSION: OF is a benign fibro-osseous tumor of the craniofacial bones commonly involving the jaws, especially the mandible. The diagnosis is based on a combination of clinical, radiographic and histologic criteria. Conservative treatment is an effective option that reduces morbidity and simplifies postoperative rehabilitation. We emphasize the importance of properly documenting individual cases and interpreting postoperative radiographic images along with the patients in order to avoid possible confusion between areas of bone repair and of potentially suspicious lesions in the future.

scholarly journals Are preoperative complete blood count parameters in peripheral nerve sheath tumors useful diagnostic tools?

2021 ◽  
Vol 32 (2) ◽  
pp. 340-346
Author(s):  
Mesut Mısırlıoğlu ◽  
Aliekber Yapar ◽  
Erdem Aras Sezgin ◽  
Emin Kürşat Bulut ◽  
Galip Beltir ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Blood Count ◽  
Complete Blood Count ◽  
Control Group ◽  
Histopathological Diagnosis ◽  
Lymphocyte Ratio ◽  
Nerve Sheath Tumors ◽  
Peripheral Nerve Sheath Tumors ◽  
Nerve Sheath ◽  
Pre Treatment

Objectives: This study aims to evaluate the diagnostic value of complete blood count (CBC) parameters in patients with peripheral nerve sheath tumors (PNSTs). Patients and methods: A total of 181 patients (83 males, 98 females; median age: 44 years; range, 15 to 83 years) who underwent surgical treatment for PNSTs in our tertiary oncology center between January 2010 and December 2019 were retrospectively analyzed. Eighty-two patients were diagnosed with a neurofibroma, 79 with a schwannoma, and 20 with a malignant PNST (MPNST). The patient group was evaluated as malignant (n=20) and benign (n=161). Age- and sex-matched patients admitted to our outpatient clinic of orthopedic and traumatology with non-specific symptoms other than tumor, infection, fracture, and rheumatological or hematological diseases were included as the control group (n=165). Data including age, sex, definitive histopathological diagnosis, and pre-treatment CBC values were obtained from the hospital records. Pre-treatment CBC values such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and lymphocyte-to-monocyte ratio (LMR) were calculated for both malignant and benign groups and control groups. Diagnostic values of NLR, PLR, and LMR between PNST groups were assessed using the receiver operating characteristic (ROC) curve analysis. Results: Neurofibroma, schwannoma, and MNPST groups had significantly higher median NLR, compared to the control group (p<0.001), while the median LMR was significantly lower in these groups (p<0.05). However, the median PLR was higher only in the MPNST group, compared to the control group (p<0.001). Post-hoc analyses revealed that median NLR, PLR, and LMR ratios were similar in PNST groups, compared to the control group. In addition, the median NLR, PLR, and LMR ratios were similar between malignant and benign patient groups. The highest area under the curve (AUC) was found for NLR (AUC=0.756) and LMR (AUC=0.716) in the MPNST group. Conclusion: Our study results suggest that NLR, PLR, and LMR may have an added value in the early diagnosis of PNSTs and are valuable for differentiating patients from healthy individuals, although their value in differential diagnosis is still unclear.

scholarly journals Feline Idiopathic Pulmonary Fibrosis

2019 ◽  
Vol 47 ◽  
Author(s):  
Paula Elisa Brandão Guedes ◽  
Jeane Martinha dos Anjos Cordeiro ◽  
Roueda Aboud Said ◽  
Luci Ana Fernandes ◽  
Alexandre Dias Munhoz ◽  
...  
Keyword(s):  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Physical Examination ◽  
Respiratory Distress ◽  
Complete Blood Count ◽  
Clinical Care ◽  
Respiratory Arrest ◽  
Histopathological Findings ◽  
Microscopic Evaluation ◽  
History Of

Background: Feline idiopathic pulmonary fibrosis is an irreversible disease that is rarely reported in veterinary clinical routine, with this case as the second reported in Brazil. This study aimed to describe a case of idiopathic pulmonary fibrosis in a domestic cat.Case: A 10-year-old female cat with a history of respiratory distress was treated at the Veterinary Hospital of the State University of Santa Cruz (HV-UESC). The first signs were observed three months before clinical care, characterized mainly by dyspnea that was more pronounced during nighttime. There was no history of previous illnesses or prior drug use. The cat lived with two other domiciled cats, did not have access to the street, and had restricted access to the terrace of the building, from where other animals could have possibly entered. Physical examination showed a poor body condition with a temperature of 37°C and dehydration estimated at 9%.The animal was observed to remain in an orthopedic position, with tachypnea (109 mvm), wheezing through the mouth, and severe expiratory dyspnea. Pulmonary auscultation detected fine discontinuous adventitious noises. There were no changes in the cardiac function in terms of rhythm, frequency, or auscultation. Oxygen therapy and slow administration of 0.9% NaCl solution were performed; moreover, blood was collected for complete blood count, in which no abnormalities were observed. Thoracic radiography was performed on the cat, and the results showed a mixed pulmonary pattern characterized by bronchiectasis, thickening of the bronchiolar wall, and an unstructured interstitial pattern throughout the pulmonary area. Shortly after the beginning of the clinical care, the animal died due to respiratory arrest and was necropsied. The main macroscopic finding was pulmonary edema. Lung samples were subjected to microscopic evaluation, which revealed extensive multifocal areas of alveolar septa thickening characterized by smooth muscle hyperplasia, hypertrophy associated with intense fibroplasia, type II pneumocyte hyperplasia, and discrete intra-alveolar and interstitial lymphohistiocytic inflammatory infiltrate. Based on the clinical, radiographic, macroscopic, and histopathological findings, the diagnosis of idiopathic pulmonary fibrosis was established. Discussion: This is the second case of feline idiopathic pulmonary fibrosis reported in Brazil. The observations in the physical examination, namely, the orthopedic positioning, dyspnea, and mouth breathing, are characteristic of respiratory distress and showed the severity of the lesions in the respiratory system. The clinical manifestation of idiopathic pulmonary fibrosis in cats reveals that gas exchange had already been compromised, which indicates an advanced stage of disease. In addition to respiratory signs, systemic signs such as apathy, anorexia, weight loss, and dehydration also confirm the severity of the condition. Because of the severity of the clinical condition at the time of the clinical care, it was not possible to adopt a more aggressive therapeutic approach, and the animal eventually died. Taken together, the clinical, radiographic, macroscopic, and histopathological findings led to the diagnosis of idiopathic pulmonary fibrosis. Literature states that the diagnosis of idiopathic pulmonary fibrosis requires clinical, radiographic, and histopathological findings consistent with the alterations observed in this cat. Much remains to be understood with regard to idiopathic pulmonary fibrosis in felines, since the currently available information is sparse and divergent. The description of these cases is extremely important to increase the available knowledge and to improve the prognosis and therapy for this serious disease.

Sign in / Sign up

Export Citation Format

Share Document