scholarly journals Etiological classification of seizures in pediatric age group (6-12years) – MRI study

2021 ◽  
Vol 9 (4) ◽  
pp. 257-262
Author(s):  
Dr. Nirmalkumar Gopalakrishnan ◽  
◽  
Dr. Mohammed Ansari Gaffoor ◽  

Background: A seizure is an occurrence of signs or symptoms due to abnormal excessive orsynchronous neuronal activity in the brain. The present study aims to study the etiological factorsand clinical profile for new-onset seizures in children aged 6-12 years and to determine thefrequency of Magnetic resonance imaging (MRI) abnormalities in the pediatrics age group with new-onset unprovoked seizure and those with inadequately investigated longstanding epilepsy andclassify the etiology based on the MRI findings. Methods: A prospective study involving a total of 50patients was recruited aged between 6 to 12 years. All of them underwent neuro-imaging with MRI.Uncooperative patients were imaged following sedation and monitoring by the anesthetist. Allchildren aged 6-12 years who presented with new-onset seizures were included. All MR images wereobtained at a 3-mm section thickness except magnetization-prepared rapid gradient-echo images,which are obtained at a 1.8-mm section thickness. Results: Of the 50 patients 28 presented withgeneralized tonic-clonic seizures, 12 with simple partial seizures, 10 with complex partial seizures.Generalized seizures were a more common presentation than partial seizures in children 6-12 yearsof age. Conclusion: With the positivity of the MRI in the new-onset seizure in children between 6-12 years in our study gives an important aspect of the essential factor of imaging in pediatric new-onset seizures.

Author(s):  
Nishant Raj ◽  
Rajasbala Pradeep Dhande

Background: Seizures are a common presenting complaint in pediatric patients. There are many underlying causes which may present as seizures in pediatric population, for example: febrile seizures, hypoxic ischemic encephalopathy, congenital malformations, certain neoplasms etc. Magnetic resonance imaging(MRI) plays a fundamental role in evaluation of these causes and is especially of use in identifying the structural lesions presenting as seizures. Objectives: To assess the role of MRI(1.5 Tesla) in evaluation pediatric seizures and to study spectrum of MRI findings associated with various causes. Methodology: A prospective study will be conducted at “Acharya Vinoba Bhave Rural Hospital, Sawangi”, involving 138 pediatric patients coming to Radiology department. Results: After statistical analysis, we expect to find effectiveness of MRI in evaluation of pediatric seizures. Conclusion: In this study we expect to find usefulness of MRI as a diagnostic tool in assessment of pediatric seizures especially in those with structural lesions.


Cephalalgia ◽  
1983 ◽  
Vol 3 (2) ◽  
pp. 115-118 ◽  
Author(s):  
G. Lanzi ◽  
U. Balottin ◽  
A. Ottolini ◽  
F. Rosano Burgio ◽  
E. Fazzi ◽  
...  

A retrospective method was used to estimate the incidence of recurring motion-sickness, cyclic vomiting and abdominal pain considered as different manifestations of a so-called periodic syndrome in 100 migraine sufferers, 100 epileptics and 100 control subjects in the pediatric age group. Such recurrent symptoms are significantly more frequent in those suffering from migraine than in the other two groups. Examination of subgroups of patients affected by particular forms of migraine (classical and common) and of epilepsy (generalized seizures, simple partial seizures, complex partial seizures) contributed little new to our understanding of the nature of periodic syndrome. It is concluded that the above symptoms of periodic syndrome should generally be considered as manifestations of a migrainous rather than of an epileptic disorder.


2021 ◽  
Vol 11 (2) ◽  
pp. 253-257
Author(s):  
Sunil Kumar Agarwalla

Seizure in children are generally indicating a potentially serious underlying systemic or CNS disorders that require thorough clinical examination, investigation and management. It is therefore important to establish accurate diagnosis of seizure and its etiology to manage such patients appropriately. We carried out this study to evaluate different etiology of seizures and its correlation with abnormal EEG & abnormal neuroimaging in the age group of 2mo to 14 years. 200 children presented with seizure to our department from January 2019 to November 2020 were enrolled in this prospective hospital-based study. Detailed history, clinical examination, investigation with special emphasis to EEG & neuroimaging was done and different correlation was drawn by using SSPS 18.0 statistical analysis. Among 200 cases, 6 to 10yr. age group constituted maximum (49%) number of cases. Male to female ratio is 1.5:1. GTCS is the predominant pattern of seizure (60%) in all age groups. EEG abnormality is found in 45%, mostly in focal seizure type. Neuroimaging abnormality found in 29%. Maximum cases (30%) had infectious etiology. Childhood seizure needs detailed history taking and careful examination. Vedio recording shown by parents / caregivers really help towards differentiating seizure from seizure mimics. EEG has a role in specific seizure type; Neuroimaging at times helps in diagnosis. There are few studies that describe neuroimaging [Computed Tomography (CT) and Magnetic Resonance Imaging (MRI)] and Electroencephalogram (EEG) data in children who present with new-onset seizures. The EEG is recommended as a part of the neurodiagnostic evaluation of the child with an apparent first unprovoked seizure.


2020 ◽  
pp. 63-64
Author(s):  
Srenivas. A ◽  
Sathiya Suresh

Seizures represent signal of neurological disease in the newborn period and these convulsive phenomena are the most frequent of the overt manifestation of neonatal neurological disorders.. The objective of this study was to study the incidence of pediatrics (0-12 years) seizures. To study the etiology and pattern of seizures. Methods: 200 Subjects who had seizures were included in the study. Relevant history was ascertained from a patient’s parents or a reliable relative or attendant, medical records and the referring physicians note, specifically from mother in case of neonatal seizures i.e. age at onset of seizures, seizure activity with special emphasis on occurrence of 1st seizures, duration of seizures, number and type of seizures, associated autonomic changes, medications required to control seizures, response time to medications, and possible causes for determination of etiology. A detailed antenatal, natal and postnatal history was taken. Results: Out of 200 study subjects 35.89% were in neonatal age group, of which 64.10% and 35.90% were male and female respectively and 64.11%. out of neonatal seizures, 64.10% neonates were male and 35.90% were female. Male: Female ratio was 1.79:1. The seizures were common in male neonates. Subtle seizures were the commonest type of seizures observed both in term and preterm neonates. Conclusions: The various types of seizure were compared with the preterm and term neonates and it was found statistically significant


1992 ◽  
Vol 27 (2) ◽  
pp. 241-245 ◽  
Author(s):  
P. Dillon ◽  
H. Maurer ◽  
J. Jenkins ◽  
T. Krummel ◽  
D. Parham ◽  
...  

2019 ◽  
Vol 6 (2) ◽  
pp. 774
Author(s):  
Rinu Dwivedi ◽  
P. Sudha Priya ◽  
P. Padmavathi

Background: Seizures are common in pediatric age group and less than 1/3rd of seizures in children are caused by epilepsy. Aim of present study was to analyze the etiological factors and clinical profile of new onset seizures in children aged 3-12 years.Methods: This was a prospective study done at a tertiary care center of south India. Authors analyzed 98 children aged 3-12 years presenting with new onset seizures. Proper history and investigations including EEG, and CT brain were done to confirm the etiology.Results: Out of 98 children 51 were 3-5 yrs of age and 47 were 6-12 years. 66.3% had generalized seizure and 33.6% had partial seizure. Partial seizure were more common in 5-12 years of age. Intracranial infections were the leading cause (73/98) which included neurotuberculosis (26/73), NCC (20), bacterial meningitis (12), cerebral malaria (8) and viral encephalitis (7). Intracranial infections  were the  leading cause in both age groups. Space occupying lesions were more common in 6-12 years (46.8%) as compared to 3-5 years (19.6%). NCC and Tuberculoma were the leading CT findings in both age groups. There was significantly high incidence of focal EEG changes in partial seizure group compared to generalized seizure group.Conclusions: Intracranial infections were leading cause of new onset seizures especially GTCS. Good clinical evaluation and judicious use of investigations should be ensured. CT brain and EEG are more likely to be informative in partial seizures than in generalized seizures.


2020 ◽  
pp. 1-3
Author(s):  
Sandhya Bordia ◽  
Praveen Kumar Jain*

OBJECTIVE: The purpose of this prospective study is to study the spectrum of pediatric solid malignancies at our institution. METHOD: This study is under taken to evaluate the incidence and morphological features of solid malignant paediatric tumors in eighteen years and below. The material for present study is obtained from FNAC in cytology and biopsy specimen in histology department of RNT Medical college, Udaipur. RESULT: A total number 60 cases of malignant solid pediatric tumors of age group 0-18 years were diagnosed in Department of Pathology RNT Medical college Udaipur, during a period of two years. The number of malignancies diagnosed by Cytology accounted for 53.33% while Histopathology contributed 46.67% respectively. The male: Female ratio of childhood solid malignancies was 1.73:1. In malignant solid pediatric tumors CNS tumors were the commonest constituting 30% followed by Lymphoma 23.33%, Bone tumors 11.67% and neuroblastoma, retinoblastoma & spindle cell neoplasm 3.33% each. CONCLUSION: Our study concluded that solid malignant pediatric tumors contribute also a health problem in Udaipur region affecting all pediatric age group but more prevalent in the age group 6-10 years & 15-18 years.


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