Clinical presentations of polycystic ovary syndrome in a tertiary care centre of southern Rajasthan, India

Introduction: The study of lower genital tract trauma has become important in gynaecological practice. There is paucity of reports on this clinical entity from our settings. The main aim of this study is to document injuries in female lower genital tract in Mid-Western Nepal. Methods: Sixty female patients admitted to the hospital with genital tract injuries caused by coitus or accidents were included in the study. Details of the causes of trauma clinical presentations and management were recorded. Results: These injuries were grouped according to etiological factors. This study included 33 (55%) coital injuries and 27 (45%) non- coital injuries. Out of coital injury, 12 cases were criminal assault (rape) in age group of 4 to 18 years. Four unmarried girls had consensual sex. Non-coital injuries were due to fall from height, cattle horn injuries, straddle type of trauma, vulvar haematoma and anorectal injuries. Conclusions: Appropriate surgical intervention can avert morbidity and mortality. Keywords: accident; lower genital tract; Nepal; trauma.

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Prevalence of metabolic syndrome in women with polycystic ovary syndrome attending an infertility clinic in a tertiary care hospital in south India

Journal of Human Reproductive Sciences ◽

10.4103/0974-1208.97791 ◽

2012 ◽

Vol 5 (1) ◽

pp. 26 ◽

Cited By ~ 19

Author(s):

Korula George ◽

Kavita Mandrelle ◽

MohanS Kamath ◽

DianJ Bondu ◽

Achamma Chandy ◽

...

Keyword(s):

Metabolic Syndrome ◽

Polycystic Ovary Syndrome ◽

South India ◽

Tertiary Care Hospital ◽

Polycystic Ovary ◽

Tertiary Care ◽

Care Hospital ◽

Ovary Syndrome

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Evaluation of Various Etiological Factors & Clinical Presentations of Epididymo-Orchitis at a Tertiary Care Centre

Journal of Medical Science And clinical Research ◽

10.18535/jmscr/v4i5.48 ◽

2016 ◽

Author(s):

Navneet Parashar ◽

Keyword(s):

Tertiary Care ◽

Care Centre ◽

Tertiary Care Centre ◽

Etiological Factors ◽

Clinical Presentations

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Assessment of serum adiponectin levels in women with polycystic ovary syndrome

Obsgyne Review: Journal of Obstetric and Gynecology ◽

10.17511/joog.2021.i02.01 ◽

2021 ◽

Vol 7 (2) ◽

pp. 21-27

Author(s):

Dr. Mukund B. Patel ◽

◽

Dr. Ramesh C. Patel ◽

Keyword(s):

Polycystic Ovary Syndrome ◽

Polycystic Ovary ◽

Tertiary Care ◽

Fasting Blood Glucose ◽

Hdl Cholesterol ◽

Study Groups ◽

Reproductive Age ◽

Serum Adiponectin ◽

Ovary Syndrome ◽

Healthy Women

Background and Aim: Serum adiponectin levels were found to be altered in women with polycysticovary syndrome (PCOS) due to the increased adiposity commonly observed in them. Accordingly,earlier studies have reported decreased adiponectin levels in PCOS women. the present study wasconducted to measure serum adiponectin levels in women with PCOS and to evaluate its associationwith the biochemical parameters studied.Material and Methods: The present study included 50women of reproductive age attending the department of Gynecology, tertiary care institute of Indiaand diagnosed with polycystic ovary syndrome based on Rotterdam criteria. Fifty age-matchedhealthy women were recruited as controls. t. Adiponectin levels were measured along withmeasurement of fasting blood glucose, lipid profile using commercial kits and insulin resistance(HOMA-IR) was calculated. Results: Both the study groups were matched concerning age, however,PCOS women were obese when compared to healthy women (p<0.001). Serum total cholesterol andtriglyceride levels were significantly higher (p≤0.05) and serum adiponectin concentration wassignificantly lower in PCOS women when compared to controls (p≤0.05). HDL cholesterol, fastinginsulin and HOMA-IR were similar between cases and controls. Adiponectin did not show significantassociation with any of the parameters studied (Table 2). Conclusion: Serum adiponectin levels aresignificantly lower in women with polycystic ovary syndrome compared to healthy women. Thehyperandrogenemia which is one of the characteristic features of PCOS leads to a state of adipositywhich can further cause a decrease in adiponectin levels.

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A study of metabolic syndrome in women with polycystic ovary syndrome at tertiary care center

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20212187 ◽

2021 ◽

Vol 10 (6) ◽

pp. 2427

Author(s):

Chelsae Kuntal ◽

Jyotsna Vyas ◽

Asha Chaudhary ◽

Sunita Hemani ◽

Lata Rajoria

Keyword(s):

Insulin Resistance ◽

Metabolic Syndrome ◽

Polycystic Ovary Syndrome ◽

Urban Areas ◽

Polycystic Ovary ◽

Tertiary Care ◽

Reproductive Age ◽

Ovary Syndrome ◽

Hormonal Profile ◽

Increased Risk

Background: Polycystic ovary syndrome is a common endocrinopathy in women of reproductive age with prevalence of 6-10% which is characterized by hyper androgenic features and chronic oligo – anovulation and polycystic ovary morphology. Most women with polycystic ovary syndrome are also characterized by metabolic abnormalities like insulin resistance, hyperinsulinemia, dyslipidemia and abdominal obesity, these forming risk factors for metabolic syndrome. The objective of the study was to compare the clinical, biochemical and hormonal profile of polycystic ovary syndrome patients with and without metabolic syndrome.Methods: A comparative cross- sectional study was undertaken on 79 PCOS women diagnosed with PCOS according to Rotterdam criteria, in which the clinical data and hormonal profile of two groups of polycystic ovary syndrome women with and without metabolic syndrome was compared.Results: The mean age of 79 patients in this study group with and without metabolic syndrome was 26.17±3.18 and 25.57±3.41 years respectively. There were more patients from urban areas as compared to rural areas and maximum patients. Significantly higher number of PCOS women with metabolic syndrome had hirsutism and acanthosis nigricans than those without metabolic syndrome. Mean value of Waist circumference, systolic BP pressure, diastolic BP, S. Triglyceride and fasting glucose were higher and HDL levels were lower in women with metabolic syndrome than those without metabolic syndrome. Fasting insulin and HOMA-IR values were significantly higher in PCOS women with metabolic syndrome in comparison to those without metabolic syndrome.Conclusion: PCOS is not only is the most frequent cause of anovulation, but it is also associated with characteristic metabolic disturbances that may have important implications for the long term health. Metabolic syndrome is a cluster of endocrine disturbances, including insulin resistance, dyslipidemia, obesity, and hypertension. It is associated with a two-fold increased risk of cardiovascular disease and a five-fold increased risk of type 2 diabetes. This illustrates the importance of early detection of insulin resistance and metabolic syndrome with subsequent application of preventive measures in women with polycystic ovary syndrome.

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Effects of calcium-vitamin D and metformin on the menstrual cycle and ovulation in polycystic ovary syndrome patients in a tertiary care teaching hospital

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20211117 ◽

2021 ◽

Vol 10 (4) ◽

pp. 1442

Author(s):

Gowthami Mummalaneni ◽

Krishna Kumari Myneni

Keyword(s):

Vitamin D ◽

Polycystic Ovary Syndrome ◽

Polycystic Ovary ◽

Tertiary Care ◽

Treated Group ◽

Open Label ◽

Ovary Syndrome ◽

Menstrual Cycles ◽

Follicular Response

Background: Polycystic ovary syndrome (PCOS) is a heterogeneous hormonal disorder of reproductive aged women characterized by chronic anovulation, irregular menstrual cycles and hyperandrogenism. The present study aimed to investigate the effects of metformin and calcium-vitamin D on follicular maturation and regularity of menstrual cycles in patients with PCOS.Methods: A prospective, open-label, multiple arms, randomized clinical trial. Group 1 participants received 1,000 mg of calcium and 400 IU of vitamin D per day, orally, group 2 participants received 1,500 mg of metformin per day, orally and group 3 participants received combination of above drugs. The patients were treated for 3 months and followed up for a further 3 months. Menses regularity, number of dominant follicles (≥14 mm) and pregnancy rates were compared among the three groups.Results: A total of sixty infertile women with PCOS were recruited. Calcium-vitamin D plus metformin treated patients showed highest percentage improvement (50%) menstrual regularity as compared to other two groups (p<0.001) also showed significant follicular response (p<0.014). Calcium-vitamin D plus metformin treated group showed better follicular response in the second and third month of follow-up and 30% of women showed high quality dominant large (≥14 mm) follicles at the end of follow-up period.Conclusions: Calcium-vitamin D plus metformin combination is more effective in terms of follicle maturation and restoring menstrual disturbances as compared to individual drug treatment.

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