scholarly journals SERO-EPIDEMIOLOGICAL STUDY OF HEPATITIS B, C, HIV AND TREPONEMA PALLIDUM AMONG BLOOD DONORS IN HODEIDA CITY- YEMEN

2019 ◽  
Author(s):  
Ahmed Mohsen Al-kadassy ◽  
Abdulmalik Faisal Saleh Al-Ashiry ◽  
Hassan Abdulwahab Al-Shamahy
Keyword(s):  
Blood Transfusion ◽  
Blood Donors ◽  
Blood Donation ◽  
Age Groups ◽  
Treponema Pallidum ◽  
Research Center ◽  
Age Group ◽  
Test Results ◽  
Current Prevalence

Infections transmitted in blood transfusions are the most significant concern associated with blood donation. The purpose of this study was to establish the current prevalence of hepatitis viruses (B and C), HIV and T.pallidium among blood donors at National Blood Transfusion and Research Center (NBTRC) Hodeida Branch, Hodeida city, Yemen. Serological markers of HBV, HCV, HIV 1, 2, T. pallidium antibodies were studied in 25446 (males) using commercially available kits, over a period of 3 years from January 2016 to April 2018 at National Blood Transfusion and Research Center (NBTRC) Hodeida Branch , Hodeida city, Yemen. Also, the prevalence of confirmed-positive test results of these infections was evaluated among different ages. The sero-prevalence of HBV and HCV, HIV, T. pallidium infections based on confirmation tests, were 0.74%, 0.19%, 0.38% and 0.18% respectively. The prevalence of HBV was significantly higher in age groups 37-46 years and 47-56 years with significant associated OR equal to 2.3 (p<0.001) and OR=2.7 (p=0.02) respectively. The prevalence of HCV was significantly higher in age groups 47-56 years with significant associated OR equal to 6.5 (p=0.003). The prevalence of T.pallidium was significantly higher in age group 37-46 years with significant associated OR equal to 3.6 (p<0.001). In conclusion: this study highlights the prevalence of HBV, HCV, HIV, and T. pallidium among different male ages. The prevalence varies from one age group to another, being the lowest among younger and very older age groups. Therefore, extensive recruitment of young donors should help ensure a long-term increase in the blood supply without jeopardizing safety.

scholarly journals Prévalence de la syphilis chez les donneurs de sang à la Banque du Sang d’Abéché au Tchad

2020 ◽  
Vol 14 (3) ◽  
pp. 1085-1092
Author(s):  
Djamalladine Mahamat Doungous ◽  
Abdelsalam Adoum Doutoum ◽  
Adawaye Chatte ◽  
Richard Laougangta Dounbe ◽  
Elysée Gondimo Gabdibe ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Blood Donors ◽  
Blood Donation ◽  
Treponema Pallidum ◽  
Blood Bank ◽  
Sub Saharan Africa ◽  
Prise En Charge ◽  
Afrique Subsaharienne ◽  
Cross Sectional ◽  
Transfusion Sanguine

En Afrique subsaharienne, les infections transmissibles par la transfusion sanguine comme la syphilis sont très répandues, avec une prévalence pouvant atteindre 25% chez les donneurs de sang. La présente étude avait pour objectif de déterminer la prévalence de la syphilis chez les donneurs de sang au niveau de la Banque du Sang d’Abéché. Nous avons mené une étude transversale à visée descriptive, qui s’est déroulée de mai à août 2017. Les échantillons de sang des donneurs ont été testés par immunochromatographie pour la détection des anticorps anti-tréponémiques (Biomnis®). Sur 789 donneurs de sang inclus dans l’étude, la prévalence de la syphilis était de 4,9 %. Les donneurs étaient à 96,1% de sexe masculin et 3,9% de sexe féminin. Cette prévalence était plus élevée chez les sujets âgés de [21-30] ans, chez les femmes, les donneurs non scolarisés, divorcés et les domestiques/ménagères habitant la zone d’Abéché urbaine. Ces résultats montrent qu’il est nécessaire de mettre en place une politique de suivi et de prise en charge médicale des donneurs de sang atteints de la syphilis.Mots clés: Transfusion sanguine, receveurs, Treponema pallidum, don de sang.   English Title: Prevalence of syphilis in blood donors at Abéché blood bank in ChadIn sub-Saharan Africa, infections transmitted by blood transfusion such as syphilis are widespread, with prevalence up to 25% in blood donors. The purpose of this study was to determine the prevalence of syphilis in blood donors at the Blood Bank of Abéché. It was a descriptive cross-sectional study, which ran from May to August 2017. Donor blood samples were tested by immunochromatography for the detection of anti-treponemal antibodies (Biomnis®). Of the 789 blood donors included in the study, the prevalence of syphilis was 4.9%. Donors were 96.1% male and 3.9% female. This prevalence was higher in subjects aged [21-30] years, women, out-of-school, divorced and domestic / household donors living in the urban Abéché area. These results shows that it is necessary to set up a policy of monitoring and medical care of blood donors with syphilis.Keywords: Blood transfusion, recipients, Treponema pallidum, blood donation.

scholarly journals Safety of Family Replacement Donors vs. Voluntary Non-Remunerated Donors in Komfo Anokye Teaching Hospital, Ghana: A Comparative Study

2015 ◽  
Vol 4 (1) ◽  
pp. 11-16
Author(s):  
O Addai-Mensah ◽  
PA Bashiru ◽  
EE Dogbe
Keyword(s):  
Hepatitis B ◽  
Teaching Hospital ◽  
Blood Donors ◽  
Blood Donation ◽  
Age Groups ◽  
Rapid Test ◽  
Developed Countries ◽  
Sub Saharan Africa ◽  
Age Group ◽  
Cross Sectional

Blood safety remains a challenge to many countries in sub-Saharan Africa including Ghana due to poorly planned blood donation exercises in the various communities. Blood and its products usual-ly come from two main sources; voluntary non-remunerated donors (VNRD) and family replace-ment donors (FRD). In Ghana, and in many developing countries, FRDs seem to be the major source of blood supply whilst in developed countries VNRDs are the major source. This study de-termined and compared the prevalence of four transfusion transmissible infections (TTIs); HIV, hepatitis B virus (HBV), hepatitis C virus (HCV), and Treponema palladium (TP) among FRDs and VNRDs at the Komfo Anokye Teaching Hospital to compare the safety of blood from these two groups. This cross-sectional study was undertaken at the transfusion medicine unit (TMU) of the Komfo Anokye Teaching Hospital between March and May 2014. A total of 400 blood donors (200 FRDs and 200 VNRDs) were enrolled in this study after obtaining written informed consent. Blood samples from each of the donors were then tested for HIV, hepatitis B and C, and syphilis using rapid test kits. ABO and Rhesus blood groups were also determined for all the samples. Prev-alence of TTIs was higher among FRDs (23.5%) than in VNRDs (3.5%) with males (47) been more infected than females (7). Age group 21- 30 years was the most infected, followed by age groups 31- 40 years, 11- 20 years, 41- 50 years and 51- 60 years respectively. FRDs among the younger age group, 17- 30 years, were also more infected than their VNRD counterparts. Repeat blood donors among the VNRD group, were found to be safer than their first-time counterparts. Overall, TTIs were significantly higher in the FRD group than in the VNRD group. The prevalence rates of all the infections tested were higher in the FRD group compared to the VNRD group. FRDs were the higher risk population for TTIs in comparison to VNRDs. VNRDs should therefore be encouraged to donate blood regularly.Keywords: Transfusion Transmissible Infections, HBsAg, HCV, HIV, Treponema pallidum

scholarly journals Malaria Seroprevalence in the Blood Donors of Malaria Endemic Regions of Northern Andhra Pradesh, India.

2020 ◽  
Vol 6 (8) ◽  
pp. 493-497
Author(s):  
Dr. C. Sitalata ◽  
◽  
Dr. K. Kalyan ◽  
Keyword(s):  
Blood Transfusion ◽  
Andhra Pradesh ◽  
Blood Donors ◽  
Blood Donation ◽  
Transfusion Practice ◽  
Test Results ◽  
Blood Safety ◽  
Medical Sciences ◽  
Endemic Areas ◽  
Blood Bag

Introduction: Transmission of malaria through blood transfusion continues to be a major threat tosafe blood transfusion practice. Transfusion-transmitted malaria occurs at an estimated rate of 0.25cases per 1 million blood units collected. It is significantly more common in endemic areas. Aim: Tostudy the Seroprevalence of Malaria among the blood donors in the endemic areas of NorthernAndhra Pradesh. Materials and methods: The present survey was carried out at the blood bank ofMaharaja institute of medical sciences, Vizianagaram. This includes the analysis of seroprevalence ofMalaria in the blood donors during the period of 1 year from February 2018 to January 2019. Two mlof the blood sample was collected in the labeled pilot tube at the time of collection of blood fromdonor tubing of the blood bag. The serum was separated. The samples were tested for Malaria byrapid antigen detection test. Results: Out of the total of 3096 blood donors, replacement donors(86.91%) were more in comparison to voluntary donors (13.08%). The seroprevalence among thereplacement blood donors was more compared to voluntary blood donors. Conclusion: Voluntaryblood donation, increasing awareness about blood donation in the general population, selection ofrepeat, non-remunerated, regular voluntary blood donors and diligent donor selection, sensitivescreening tests are most important to increase blood safety and prevent transmission of Malariathrough blood transfusion.

scholarly journals ANALYSIS OF PRE-DONATION DEFERRAL REASONS AMONGST BLOOD DONORS IN VADODARA, GUJARAT.

2019 ◽  
Vol 3 (7) ◽  
Author(s):  
Dr. Jhalak Patel ◽  
Dr. Milind Dighe ◽  
Dr. Farzana Kothari ◽  
Dr. Rahul Rajvanshi
Keyword(s):  
Blood Transfusion ◽  
Blood Donor ◽  
Health Care Policy ◽  
Blood Donors ◽  
Blood Donation ◽  
Blood Bank ◽  
Age Group ◽  
Donor Pool ◽  
Gender Based ◽  
Safe Blood

Background: Blood transfusion saves lives and improves health, but many patients requiring transfusion do not have timely access to safe blood. Providing safe and adequate blood should be an integral part of every country’s national health care policy and infrastructure. Aim: The main aim of the study was to analyze the reasons for pre-donation deferral amongst blood donors attending our blood bank and outdoor camp organized by our blood bank and to evaluate and categorize the reasons into temporary and permanent deferral. Materials and methods: It is a Record based Retrospective Study conducted in Department of Immunohematology and blood transfusion over a period of two years from July 2015 to July 2017. The reasons of deferral were analyzed after classification into following categories, namely, temporary- permanent deferral, in-house –camp blood donors, gender-based (male -female), and various age group categories. Results: A total of 30,022 prospective blood donors registered for blood donation out of which 2241 blood donors were deferred (7.46%) with low hemoglobin level, medication and hypertension as top three causes. The majority of deferral was seen in 18-25 years of age group which mainly comprises the youth population. The female donors were rejected eight times the male donors. Conclusion: The knowledge of the deferral incidences and their causes in a particular region helps in deciding the magnitude and the direction of the blood donor recruitment efforts. This knowl­edge also helps in calculating the eligible and the potential blood donor pool. Keywords: Blood Donors, Pre-Donation, Deferral, Temporary, Permanent.

scholarly journals Predictive Value of Technical Throwing Skills on Nomination Status in Youth and Long-Term Career Attainment in Handball

2022 ◽  
Vol 8 (1) ◽  
Author(s):  
Till Koopmann ◽  
Franziska Lath ◽  
Dirk Büsch ◽  
Jörg Schorer
Keyword(s):  
Logistic Regression ◽  
National Level ◽  
Age Groups ◽  
Age Group ◽  
Regression Analyses ◽  
Chi Square ◽  
Career Attainment ◽  
Future Performance ◽  
Younger Age

Abstract Background Research on talent in sports aims to identify predictors of future performance. This study retrospectively investigated 1) relationships between young handball field players’ technical throwing skills and (a) their potential nomination to youth national teams and (b) their long-term career attainment 10 years later, and 2) associations between nomination status and career attainment. Results Results from retrospectively predicting nomination status and career attainment using logistic regression analyses show that technical throwing skills were partly able to explain players’ nomination status (Nagelkerke R2: females 9.2%, males 13.1%) and career attainment (Nagelkerke R2: 9.8% for female players). Here, variables throwing velocity and time on exercise showed statistically significant effects. In addition, nomination status and career attainment were shown to be associated using chi-square tests (w of .37 and .23 for female and male players, respectively) and nomination status as a predictor increased the prediction of career attainment remarkably (Nagelkerke R2: females 20.3%, males 12.7%). Conclusions Given these results, basic technical throwing skills may serve rather as a prerequisite in this age group on national level, emphasizing its importance already on lower levels and in younger age groups. Furthermore, advantages from entering the national TID system early especially for females are discussed.

scholarly journals Blood Transfusion Service and Hospital Blood Rotation: The Implications on Transfusion Safety in Nigeria

2019 ◽  
Vol 2 (1) ◽  
pp. 19-24
Author(s):  
O D Damulak ◽  
E D Jatau ◽  
E Ekam ◽  
E Rumji ◽  
R Yakubu ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Diagnostic Test ◽  
Rapid Diagnostic Test ◽  
Blood Donors ◽  
Blood Donation ◽  
Tertiary Hospital ◽  
Sub Saharan Africa ◽  
High Rate ◽  
Blood Transfusion Service ◽  
First Time

Blood donation is not readily an altruistic sacrifice in sub-Saharan Africa where microbial infections, maternal haemorrhages, malaria and other tropical diseases that frequently require blood transfusion are daily diagnoses. Blood transfusion safety is hindered by the combined prevailing high rate of Transfusion-Transmissible Infections (TTIs) and poor screening techniques. This study determined the rate of Enzyme-Linked Immuno-Sorbent Assay (ELISA) positive reactions to transfusion-transmissible infections in rapid diagnostic test negative family replacement blood units, compared to the first time voluntarily donated blood. We studied records of blood units collected in a tertiary hospital from donors who scaled pre-donation Rapid diagnostic test (RDT) screening for the human immunodeficiency virus, hepatitis B and hepatitis C viruses and syphilis and rescreened by ELISA techniques at the National Blood Transfusion Service Centre in Jos, along with units from first-time voluntary blood donors. A total of 19562 blood units; 5945 (30.39%) rapid diagnostic tests negative from a linkage hospital and 13617 (69.61%) from first time voluntary donors were screened by ELISA methods for HIV, HBV, HCV, and syphilis. The overall TTIs detected by ELISA was 16.08%, significantly lower among pre-donation rapid screened family replacement blood donors [495(8.32%)] compared to 2651 (19.47%) among first-time voluntary donors; P=0.0001. Fifty-seven (0.96%) HIV, 166 (2.79%) HBV, 137 (2.31%) HCV and 137 (2.31%) syphilis were still detected respectively by ELISA in the pre-screened negative family replacement blood units. The outcome of ELISA screenings of blood collected from first-time volunteer donors were; 143 (1.05%) HIV, 1,486 (10.91%) HBV, 683 (5.02%) HCV, and 339 (2.49%) syphilis. Blood for transfusion should be screened negative at least with ELISA.

scholarly journals A milk-borne outbreak of Campylobacter infection

1980 ◽  
Vol 84 (3) ◽  
pp. 415-419 ◽  
Author(s):  
Ian A. Porter ◽  
Thomas M. S. Reid
Keyword(s):  
Campylobacter Jejuni ◽  
Attack Rate ◽  
Age Groups ◽  
Age Group ◽  
Sex Distribution ◽  
Unpasteurized Milk ◽  
Group Recovery ◽  
Campylobacter Infection ◽  
Culture Positive

SUMMARYCampylobacter jejuni was isolated from the stools of 148 patients with symptoms and 57 symptomless subjects, and from a milk sock filter, following an outbreak of enteritis associated with consumption of unpasteurized milk. The incubation period rantged from 2–11 days with a peak at 5 days. There were no secondary cases. The attack rate was around 50% Cases occured in all age groups but were maximal in the 1–10 age group. Recovery from symptoms was complete in the majority in less than 1 week. No long term excretors were indentified. There were no differences between culture positive individuals, with or without symptoms, in age or sex distribution or duration of excretion.

Perceived Exertion in Isometric Muscular Contractions Related to Age, Muscle, Force Level and Duration

1992 ◽  
Vol 36 (10) ◽  
pp. 712-716 ◽  
Author(s):  
Joseph M. Deeb ◽  
Colin G. Drury
Keyword(s):  
Perceived Exertion ◽  
Muscle Force ◽  
Age Groups ◽  
Muscle Group ◽  
Isometric Contractions ◽  
Age Group ◽  
Perceived Effort ◽  
Muscle Groups ◽  
Different Levels

This research was concerned with studying the development and growth of perceived effort of long-term isometric contractions as a function of muscle group (biceps vs quadriceps), of subjects with different age groups (20–29 vs. 50–59 years old) on long-term muscular isometric contractions (5 minutes) at different levels of %MVC (20, 40, 60, 80 and 100 %MVC). An experiment testing 20 subjects each performing 10 conditions (two muscle groups × five levels of %MVC) showed that the older age group reported Significantly higher perceived exertion at higher levels of %MVC and across time. Furthermore, subjects experienced a higher and faster increase in their perceived exertion when the level of %MVC and time increased.

Analysis of the Relative Age Effect in Elite Youth Judo Athletes

2015 ◽  
Vol 10 (8) ◽  
pp. 1048-1051 ◽  
Author(s):  
David H. Fukuda
Keyword(s):  
Age Groups ◽  
Age Effect ◽  
Effect Sizes ◽  
Competitive Advantages ◽  
Age Group ◽  
Relative Age ◽  
Relative Age Effect ◽  
Birth Month ◽  
Judo Athletes

The purpose of this investigation was to evaluate relative age effects (RAEs) in elite youth judo athletes from different chronological age groups, between sexes, and across weight categories. Data from 1542 place winners of the cadet (under 17 y, 2009-2013) and junior judo world championships (under 20/21 y, 1990-2013) were separated by birth month into quarters (Q1, Q2, Q3, and Q4). The observed values were compared with expected annual age distributions using χ2 analyses, and odd ratios (OR) were used to evaluate effect sizes between quarters. The observed frequency of place winners was significantly different from the expected frequency for the age-group and sex comparisons and all body-mass groups (P < .05) with the exception of the extra-light categories (P = .572). When comparing Q1 with Q4 (OR, 95% confidence interval), small effect sizes were observed for cadets (1.72, 1.12-2.66), juniors (1.54, 1.23-1.94), males (1.75, 1.32-2.33), females (1.39, 1.03-1.87), and the light- (1.79, 1.21-2.64) and middle-weight (1.80, 1.20-2.70) categories. RAEs are apparent in cadet and junior judo athletes. Thus, coaches and administrators should consider the potential for physical and/or competitive advantages while adopting strategies that encourage long-term participation in youth judo athletes.

scholarly journals A comparative study of the epidemiology of Treponemal Infection in the Volta Region of Ghana: A Five-Year Multisite Parallel Population-Based Analysis vis-à-vis the Sentinel Survey

2019 ◽  
Author(s):  
Sylvester Yao Lokpo ◽  
Ellis Owusu-Dabo ◽  
John Gameli Deku ◽  
Verner Ndudiri Orish ◽  
Gideon Kye-Duodu ◽  
...  
Keyword(s):  
General Population ◽  
Pregnant Women ◽  
Blood Donors ◽  
Blood Donation ◽  
Age Groups ◽  
Population Based ◽  
Gender Disparity ◽  
Treponemal Infection ◽  
Volta Region ◽  
Study Sites

Abstract Abstract Background: Treponemal infection is contagious and one of the oldest blood-borne infections, with great public health consequences. This study aimed to comparatively describe the five–year (2013-2017) regional epidemiology of Treponemal infection using pregnant women in the Sentinel Survey and apparently healthy blood donors as proxy for the general population at the four sentinel sites in the Volta Region of Ghana. Method: We analysed retrospectively data from 17,744 prospective blood donors aged between 18 to 58 years and 7,805 pregnant women in a Sentinel Survey who fell within the 15 and 49 years age bracket at Hohoe, Ho, Tongu and Krachi-West sentinel sites in the Volta Region. Data extracted included age, gender, date of blood donation and Treponena pallidum chromatographic immunoassay results from the blood banks of the four study sites. Published reports of Sentinel Surveys conducted at the four sentinel sites from the years 2013-2017 were retrieved. Results: The cumulative five-year prevalence of Treponemal infections among the pregnant women in the Sentinel Survey and prospective blood donors was 0.38% and 2.38% respectively. Site-specific prevalence for population-base/Sentinel survey was 4.6%/0.4%, 2.0%/0.2%, 1.3%/0.8 and 1.2%/0.2 for Hohoe, Ho, Krachi-West and Tongu respectively. Treponemal infection rates among the younger age groups (15-24years) were 0.31% in the sentinel survey and 2.22% in the general population. Significant gender disparity in Treponemal infection exist with male preponderance. Conclusion: The regional prevalence of Treponemal infection in the Sentinel Survey is lower compared to the general population. Therefore, the use of pregnant women as proxy for population estimate could lead to underestimation of the burden in the study jurisdiction.

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