Distribution of ABO blood group in children with acute leukemias

Introduction: This study is the fi rst study about the distribution ABO blood types at children with acute leukemia in Federation of Bosnia and Herzegovina. The aim of the study is to point out distribution of blood type groups at children with acute leukemia (AL)Methods: The number of children in this study was the following: 145 children with acute leukemia and 27 of children with acute myeloblastic leukemia (AML). All of the children were treated at Hemato- Oncology Unitof Pediatric Clinic in Sarajevo, in the period January 2000 until December 2010. Age of children was between 1 month and 15 years.Results: The results showed that different blood types were registered in 93. 1% of children who got ill and treated from acute leukemia for the mentioned period. At 6. 9 % of children, none of the blood types wereregistered. It was noticed that 40.9 % children who have registered blood type O, 37% blood type A,16% blood type B and 6.5% blood type AB had AL, too. It has been observed that children with following bloodtypes had AML: O, 47.8%, A, 47.7% and AB, 30.4%.Conclusion: Signifi cance ABO types distribution was confi rmed for children with ALL, p<0, 05. The analysis of the distribution of ABO types based on gender showed that signifi cance was confi rmed at females with both ALL and AML (p<0.05).

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Frequencies of feline blood types in Hungary

Acta Veterinaria Hungarica ◽

10.1556/004.49.2001.4.1 ◽

2001 ◽

Vol 49 (4) ◽

pp. 369-375 ◽

Cited By ~ 13

Author(s):

Nóra Bagdi ◽

Melinda Magdus ◽

E. Leidinger ◽

Judith Leidinger ◽

K. Vörös

Keyword(s):

Blood Transfusion ◽

Blood Group ◽

Diagnostic Method ◽

Type A ◽

Blood Groups ◽

Blood Type ◽

Type B ◽

Blood Types ◽

Type Ab ◽

Transfusion Reactions

Feline blood group determination is done as a routine diagnostic method in numerous countries. Blood transfusion reactions and feline neonatal isoerythrolysis (FNI) can be avoided with the identification of different feline blood groups. The present study is the first investigation in Hungary during which 100 cats have been examined from all over the country. These cats were out of six breeds: European domestic shorthair, Persian mix, Persian, Abyssinian, Siamese and British shorthair. In the Hungarian feline population European domestic shorthair are most common but other breeds also occur. European domestic shorthair, Persian mix, Abyssinian, Siamese and British shorthair individuals all belonged to blood type A (100%). Blood type B was found very rarely and only in Persian cats. One-third of the Persian cats were categorised into blood type B, whilst type AB was not found during the study.

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Prognostic Role of ABO Blood Type in Operable Esophageal Cancer: Analysis of 2179 Southern Chinese Patients

Frontiers in Oncology ◽

10.3389/fonc.2020.586084 ◽

2020 ◽

Vol 10 ◽

Author(s):

Shuishen Zhang ◽

Minghan Jia ◽

Xiaoli Cai ◽

Weixiong Yang ◽

Shufen Liao ◽

...

Keyword(s):

Blood Group ◽

Disease Free Survival ◽

Blood Type ◽

Chinese Patients ◽

Abo Blood Group ◽

Prognostic Impact ◽

Type B ◽

Blood Types ◽

Southern Chinese ◽

Abo Blood Type

BackgroundThe prognostic value of ABO blood types is not well clarified for esophageal carcinoma (EC). This study attempted to elucidate the associations between different ABO blood types and disease-free survival (DFS) and overall survival (OS) of EC.MethodsThis study was a retrospective review of the records of 2179 patients with EC who received surgery from December 2000 to December 2008. The prognostic impact of ABO blood group on DFS and OS were estimated using the Kaplan-Meier method and cox proportional hazard models.ResultsUnivariate analyses found significant differences in DFS and OS among the four blood types. Multivariate analyses showed ABO blood type independently predicted DFS (P=0.001) and OS (P=0.002). Furthermore, patients with non-B blood types had a significantly shorter DFS (HR=1.22, 95%CI:1.07–1.38, P=0.002) and OS (HR=1.22, 95%CI:1.07–1.38, P=0.003) than patients with blood type B, and patients with non-O blood types had a significantly better DFS (HR=0.86, 95%CI:0.77–0.96, P=0.006) and OS (HR=0.86, 95%CI:0.77–0.96, P=0.007) than patients with blood type O. Subgroup analyses found that blood type B had a better DFS and OS than non-B in patients who were male, younger, early pathological stages and had squamous-cell carcinomas (ESCC). Blood type O had a worse DFS and OS than non-O in patients who were male, younger, and had ESCC (P<0.05).ConclusionsThe results demonstrate that ABO blood group is an independent prognostic factor of survival, and that type B predicts a favorable prognosis, whereas type O predicts an unfavorable prognosis for survival in patients with EC, especially those with ESCC.

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Signalment and Blood Types in Cats Being Evaluated as Blood Donors at Two Italian University Blood Banks

Veterinary Medicine International ◽

10.1155/2014/704836 ◽

2014 ◽

Vol 2014 ◽

pp. 1-3 ◽

Cited By ~ 7

Author(s):

Eva Spada ◽

Arianna Miglio ◽

Daniela Proverbio ◽

Maria Teresa Antognoni ◽

Giada Bagnagatti De Giorgi ◽

...

Keyword(s):

Blood Donors ◽

Type A ◽

Blood Type ◽

Transfusion Reaction ◽

Type B ◽

Blood Typing ◽

Blood Types ◽

Blood Banks ◽

Type Ab ◽

Transfusion Reactions

Data from potential feline blood donors presented at two university blood banks in Italy were recorded. Blood typing was performed using an immunochromatographic method. Over the three years of the study 357 cats representing 15 breeds, 45.3% female and 54.7% male, with a mean age of 3.8 years were evaluated. Of these 90.5% were blood type A, 5.6% type B, and 3.9% type AB. The majority of the cats (54.6%) were European DSH (92.3% were type A, 5.1% type B, and 2.6% type AB), and 21% were Maine Coon (MCO) cats (100% blood type A). The estimated frequencies of transfusion reactions following an unmatched transfusion between DSH (donors and recipients), MCO (donor and recipients), DSH donors and MCO recipients, and MCO donors and DSH recipients were 4.8%, 0%, 0%, and 5.1% for major reactions and 7.2%, 0%, 7.7%, and 0% for minor transfusions reactions, respectively. In a population of blood donors that includes DSH and MCO the risk of transfusion reaction is between 5% and 8% if typing is not performed on donor and recipient blood. Blood typing should therefore be performed before transfusion to remove the risk of transfusion reactions due to blood type incompatibilities.

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Prevalence of Blood Types and Alloantibodies of the AB Blood Group System in Non-Pedigree Cats from Northern (Lombardy) and Southern (Sicily) Italy

Animals ◽

10.3390/ani10071129 ◽

2020 ◽

Vol 10 (7) ◽

pp. 1129 ◽

Cited By ~ 1

Author(s):

Eva Spada ◽

Roberta Perego ◽

Luciana Baggiani ◽

Elisabetta Salatino ◽

Vito Priolo ◽

...

Keyword(s):

Blood Group ◽

Southern Italy ◽

Type A ◽

Regional Studies ◽

Blood Group System ◽

Type B ◽

Blood Typing ◽

Blood Types ◽

Significant Difference ◽

Type Ab

The aims of this study were to determine the prevalence of A, B and AB blood types and alloantibodies in non-pedigree cats from two regions, one in Northern and one in Southern Italy (Lombardy and Sicily, respectively). A total of 448 samples (52.0% from Northern and 48.0% from Southern Italy) were blood typed. The prevalence of A, B and AB blood types in northern and southern cats were 91.0%, 5.2%, 3.8%, and 77.2%, 12.1% and 10.7%, respectively. The prevalence of type-A blood in southern cats was significantly lower (p = 0.0001) than in northern cats, while type-B and AB blood were significantly higher (p = 0.0085 and p = 0.0051, respectively) in Southern compared to Northern Italian cats. Alloantibodies against type-A blood were found in 94.1% of type-B cats, 11.2% of type-A cats had alloantibodies against type-B blood, while no type-AB cats had alloantibodies with no significant difference between the two Italian populations. Type-AB prevalence in non-pedigree cats in Southern Italy was the highest reported in Europe. Italian type-A cats had the lowest worldwide prevalence of alloantibodies against type-B blood. These results highlight the usefulness of regional studies to report different prevalences in feline blood types and reinforce the importance of blood typing cats before transfusions and mating.

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N-glycolylneuraminic acid and N-acetylneuraminic acid define feline blood group A and B antigens

Blood ◽

10.1182/blood.v79.9.2485.2485 ◽

1992 ◽

Vol 79 (9) ◽

pp. 2485-2491 ◽

Cited By ~ 48

Author(s):

GA Andrews ◽

PS Chavey ◽

JE Smith ◽

L Rich

Keyword(s):

Membrane Protein ◽

Blood Group ◽

Type A ◽

Blood Type ◽

Blood Group Antigens ◽

Type B ◽

Western Blots ◽

Acetylneuraminic Acid ◽

Group A ◽

Type Ab

Abstract Blood group incompatibility causes transfusion reactions and neonatal isoerythrolysis in cats. We investigated the molecular nature of the blood group antigens from cats that had blood type A, B, and AB erythrocytes. Naturally occurring anti-type B antibodies, Triticum vulgaris lectin, monoclonal antibody (MoAb) 32–27, and MoAb R-24 were used in agglutination tests, Western blots, and thin-layer chromatography (TLC) enzyme immunostaining. Type A erythrocytes had NeuGc-NeuGc-Galactose-Glucose-Ceramide ([NeuGc]2GD3) where NeuGc represents N-glycolylneuraminic acid, and NeuAc-NeuGc-GD3, where NeuAc represents N-acetylneuraminic acid, and may have [NeuGc]2 disialylparagloboside and NeuAc-NeuGc-disialylparagloboside. Type B erythrocytes only had [NeuAc]2GD3. Type AB erythrocytes had [NeuGc]2GD3, NeuAc-NeuGc-GD3, and [NeuAc]2GD3. Blood group antigens were also found on a 50-Kd membrane protein. We conclude that type B erythrocytes are characterized by [NeuAc]2GD3 as the only form of this ganglioside and the presence of NeuAc on a 50-Kd membrane protein. NeuGc is the major determinant of the A antigen; specifically, [NeuGc]2GD3 is the major glycolipid form. The A antigen is also present on a 50-Kd membrane protein.

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ABO blood group and the risk of breast cancer: Multicenter, case-control, observational study.

Journal of Clinical Oncology ◽

10.1200/jco.2012.30.15_suppl.1572 ◽

2012 ◽

Vol 30 (15_suppl) ◽

pp. 1572-1572

Author(s):

Yuksel Urun ◽

Tulay Koru-Sengul ◽

Kadri Altundag ◽

Gungor Utkan ◽

Handan Onur ◽

...

Keyword(s):

Breast Cancer ◽

Prognostic Factors ◽

Blood Group ◽

Blood Groups ◽

Blood Type ◽

Abo Blood Group ◽

Abo Blood Groups ◽

Blood Types ◽

Abo Blood Type

1572 Background: The role of genetic factors in the development of cancer is widely accepted. ABO blood type is an inherited characteristic and previous studies have observed an association between ABO blood group and risk of certain malignancies, including pancreatic and gastric cancer. The data on the role of ABO blood group and Rh factor in breast cancer is inconclusive. Methods: All patients who had breast cancer (BC) and treated between 2000-2010 at the Departments of Medical Oncology of both Ankara and Hacettepe Universities (Ankara, Turkey) with defined ABO blood type and Rh factor were included in our retrospective reviews of tumor registry records. A group of volunteer healthy women donors of Turkish Red Crescent between 2004-2011 were identified as a control group, without any matching factors. The relationship of ABO blood types and Rh factor with various prognostic factors such as age at diagnosis, menopausal status, family history of breast cancer, and ER/PR/HER2 status were evaluated from 1740 BC patients. We compared the distributions of ABO blood types, Rh factors among 1740 patients and 204,553 healthy controls. Among BC patients, differences between each of aforementioned ABO blood groups and Rh factors with respect to various prognostic factors were explored, respectively. Results: Overall distributions of ABO blood groups as well as Rh factor were comparable between patients (44% A, 8% AB, 16% B, 32% O, 88% Rh+) and controls (41% A, 8% AB, 16% B, 35% O, 87% Rh+). However, there were statistically significant differences between patients and controls with respect to A vs. nonA (p=0.019) and marginal significance (p=0.051) for O vs. nonO. Among patients, there were statistically significant differences between A and nonA with respect to HER2 (p=0.0421), M stage (p=0.0447), T stage (p=0.0020). Only T stage (p=0.0337) were significantly different between O vs nonO. Grade (p=0.0227) and M stage (p=0.0107) were significantly different between Rh factors. Conclusions: In our study sample, ABO blood type was statistically significantly associated with breast cancer. Additional studies are necessary to determine the mechanisms by which ABO blood type may influence the risk of breast cancer.

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Effect of maternal ABO blood type on birth weight and preeclampsia

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20172308 ◽

2017 ◽

Vol 6 (6) ◽

pp. 2164 ◽

Cited By ~ 2

Author(s):

Fatma Beyazıt ◽

Eren Pek ◽

Aysenur Çakır Güngör ◽

Meryem Gencer ◽

Mesut A. Unsal

Keyword(s):

Birth Weight ◽

Low Birth Weight ◽

Blood Group ◽

Pregnancy Outcomes ◽

Adverse Pregnancy Outcomes ◽

Blood Type ◽

Abo Blood Group ◽

Abo Blood Groups ◽

Type B ◽

Adverse Pregnancy

Background: ABO blood group has been recognized as a risk factor for distinct disease states. The association between ABO blood group and adverse pregnancy outcomes has not been extensively studied, especially in relation to birth weight and preeclampsia (PE). The aim of the present study is to determine whether ABO blood group contributes to the adverse pregnancy outcomes including low birth weight and PE.Methods: Medical data including ABO phenotypes were collected from hospital electronic database and retrospectively reviewed. Adverse pregnancy outcomes included PE and low birth weight. Birth week was also noted for each subject.Results: 2177 charts of mothers who had given birth in our hospital were studied. Overall 605 (27.8%) women had type O blood, 1056 (48.5%) had type A blood, 369 (16.9%) had type B blood and 147 (6.8%) had type AB blood. Pregnant women with type B blood group had significantly lower birth weights compared with type O, A and AB. Birth weeks of all groups were found to be similar with no statistically significant difference. A total of 167 mothers were recorded as having PE. No association was observed between PE and ABO blood groups of study participants.Conclusions: Although maternal ABO phenotype is associated with low birth weight, no association was found between blood type and preeclampsia. We postulate that maternal/fetal immune system genes which are directly associated with ABO blood groups could affect pregnant with a resulting birth weight alterations.

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Maternal ABO Blood Group Type B: A Risk Factor in the Development of Neonatal Group B Streptococcal Disease

PEDIATRICS ◽

10.1542/peds.62.4.504 ◽

1978 ◽

Vol 62 (4) ◽

pp. 504-509

Author(s):

Joan A. Regan ◽

Solan Chao ◽

L. Stanley James

Keyword(s):

Blood Group ◽

Receptor Site ◽

Blood Type ◽

Abo Blood Group ◽

Type B ◽

Group B Streptococci ◽

Group Type ◽

Increased Risk ◽

Blood Group Type ◽

Group B

In a prospective study of maternal genital colonization with group B streptococci (GBS) at the time of delivery, epidemiological data, including blood type (ABO group), were recorded for the 1,062 patients studied. Blood type B was found in a statistically significant higher proportion of patients colonized with CBS (28%) compared with the total population (16.4%) (P < .005, x2 = 8.43). Women with blood type B were twice as likely to be colonized as those with types 0 or A. Hypotheses to explain this observation include the possibilities that GBS possess a B-like antigen, rendering parturients who lack anti-B antibody at increased risk for GBS colonization, or that GBS possess a receptor site for B surface antigens. One may speculate that a mutation toward an affinity for the human ABO blood group type B accounts for the advent of the group B Streptococcus as a significant perinatal pathogen.

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Phenotypic and Genetic Characterization for Incompatible Cross-Match Cases in the Feline AB Blood Group System

Frontiers in Veterinary Science ◽

10.3389/fvets.2021.720445 ◽

2021 ◽

Vol 8 ◽

Author(s):

Yumiko Uno ◽

Masami Yaguchi ◽

Tasuku Kobayashi ◽

Eri Onozawa ◽

Kazuhiko Ochiai ◽

...

Keyword(s):

Blood Group ◽

Blood Type ◽

Blood Group System ◽

Transfusion Medicine ◽

Type B ◽

Blood Typing ◽

Group System ◽

Blood Types ◽

Incompatible Cross ◽

Cross Matching

The feline AB blood group system (blood types A, B, and AB) encoding the cytidine monophosphate-N-acetylneuraminic acid hydroxylase (CMAH) gene is the most significant in transfusion medicine and hemolysis of the newborn for cats. Blood typing and cross-matching in pre-transfusion testing are crucial to determining blood compatibility and thus prevent hemolytic transfusion reactions. We here performed serological and genetic investigations to characterize blood samples from cats with discordant results for card agglutination (CARD) and the alloantibody agglutination test for blood typing in two cats (subjects K and R). Subject K showed incompatible cross-matching in pre-transfusion testing. Red blood cells from subjects K and R determined blood type B from the CARD method showed blood type AB by alloanti-A and alloanti-B antibodies in agglutination testing. Genomic DNA sequencing of the coding region (exons 1a to 14) for the cat CMAH gene showed that subject K had four mutations with heterozygosity at c.139C>T, c.179G>T, c.327A>C, and c.364C>T. Similarly, the CMAH gene of subject R carried six mutations with heterozygosity at c.142G>A, c.187A>G, c.268T>A, c.327A>C, c.773G>A and c.1603G>A, representing a new diplotype including a novel synonymous single nucleotide polymorphism (SNP) in exon 7 (c.773 G>A: Arg258Gln). The CMAH diplotype in subjects K and R was different from major diplotype in blood type B cats. This study is the first to report CMAH variants in cats with discordant blood types between CARD and TUBE methods. These results could assist in the classification of feline AB blood types for transfusion medicine to avoid blood incompatibilities.

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DETERMINATION THE EFFECT OF IRON OVERLOAD ON VITAMIN D AND THE PERCENTAGE OF EACH BLOOD GROUPS IN PATIENTS WITH THALASSEMIA

Periódico Tchê Química ◽

10.52571/ptq.v17.n36.2020.239_periodico36_pgs_223_237.pdf ◽

2020 ◽

Vol 17 (36) ◽

pp. 223-237

Author(s):

Rusul Ali AL MASAOODI ◽

Shumoos H ALWAID ◽

Maryam Kadhim Al SHEMERY

Keyword(s):

Vitamin D ◽

Blood Group ◽

Negative Relationship ◽

Hypochromic Anemia ◽

Blood Type ◽

Control Group ◽

Blood Group System ◽

Type B ◽

Type Ab ◽

The Relationship

Thalassemia can be characterized as hereditary erythrocyte abnormalities resulting from the defect in the synthesis of the hemoglobin globin chain that leads to microcytic hypochromic anemia. This study aimed to find some relationship between the ABO system and thalassemia disease and to determine the relationship between ferritin and vitamin D in patients with thalassemia. This study estimated the level of Hb, ferritin, and vitamin D and also calculated the percentage of ABO blood types in thalassemia and non-thalassemia patients (control group). This study was conducted with 60 samples, 20 for the control group, and 40 for patients with thalassemia. The age of patients with thalassemia and controls ranged from 2 to 29 years. This study found a correlation between ferritin and vitamin D. The results demonstrated a significant reduction (p 0.05) of Hb and vitamin D, but a significant increase (p 0.05) in the concentration of ferritin. The study also found a nonsignificant negative relationship (p 0.05) between the level of ferritin and vitamin D. It was demonstrated that blood group O is more present in thalassemia patients (40%) whereas groups A, B, and AB, respectively, are present in 23%, 28%, 10% of patients. It can be concluded that patients with thalassemia are more frequent with blood type O followed by type B and, less frequently, blood type AB. Thalassemia, vitamin D, ferritin, ABO blood group system.

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