scholarly journals The Role of Hackers in Countering Surveillance and Promoting Democracy

2015 ◽  
Vol 3 (2) ◽  
pp. 77-87 ◽  
Author(s):  
Sebastian Kubitschko
Keyword(s):  
Qualitative Research ◽  
Structural Features ◽  
Anonymous Communication ◽  
Civil Society Organization ◽  
Media Technologies ◽  
Wide Range ◽  
Computer Club ◽  
Emerging Issues ◽  
Per Se

Practices related to media technologies and infrastructures (MTI) are an increasingly important part of democratic constellations in general and of surveillance tactics in particular. This article does not seek to discuss surveillance <em>per se</em>, but instead to open a new line of inquiry by presenting qualitative research on the Chaos Computer Club (CCC)—one of the world’s largest and Europe’s oldest hacker organizations. Despite the longstanding conception of hacking as infused with political significance, the scope and style of hackers’ engagement with emerging issues related to surveillance remains poorly understood. The rationale of this paper is to examine the CCC as a civil society organization that counter-acts contemporary assemblages of surveillance in two ways: first, by de-constructing existing technology and by supporting, building, maintaining and using alternative media technologies and infrastructures that enable more secure and anonymous communication; and second, by articulating their expertise related to contemporary MTI to a wide range of audiences, publics and actors. Highlighting the significance of “privacy” for the health of democracy, I argue that the hacker organization is co-determining “interstitial spaces within information processing practices” (Cohen, 2012, p. 1931), and by doing so is acting on indispensable structural features of contemporary democratic constellations.

Conceptualizing Qualitative Data

2021 ◽  
pp. 104973232110249
Author(s):  
Alex Broom
Keyword(s):  
Qualitative Research ◽  
Qualitative Data ◽  
Theory Development ◽  
Wide Range

Qualitative research is practiced across diverse disciplines and contexts, and this produces a wide range of perspectives on the role of conceptualization and theory development. It also results in a hugely varied mix of submissions to qualitative research journals in terms of their level of conceptual elevation. This editorial explores why we conceptualize qualitative data, and some common challenges evident in current qualitative practice.

The GCN5: its biological functions and therapeutic potentials

2021 ◽  
Vol 135 (1) ◽  
pp. 231-257
Author(s):  
Md. Ezazul Haque ◽  
Md. Jakaria ◽  
Mahbuba Akther ◽  
Duk-Yeon Cho ◽  
In-Su Kim ◽  
...  
Keyword(s):  
Neurological Disorders ◽  
Cellular Proliferation ◽  
Chromatin Modification ◽  
Structural Features ◽  
Histone Acetyltransferases ◽  
Epigenetic Landscape ◽  
General Control ◽  
Wide Range ◽  
Lysine Acetyltransferase

Abstract General control non-depressible 5 (GCN5) or lysine acetyltransferase 2A (KAT2A) is one of the most highly studied histone acetyltransferases. It acts as both histone acetyltransferase (HAT) and lysine acetyltransferase (KAT). As an HAT it plays a pivotal role in the epigenetic landscape and chromatin modification. Besides, GCN5 regulates a wide range of biological events such as gene regulation, cellular proliferation, metabolism and inflammation. Imbalance in the GCN5 activity has been reported in many disorders such as cancer, metabolic disorders, autoimmune disorders and neurological disorders. Therefore, unravelling the role of GCN5 in different diseases progression is a prerequisite for both understanding and developing novel therapeutic agents of these diseases. In this review, we have discussed the structural features, the biological function of GCN5 and the mechanical link with the diseases associated with its imbalance. Moreover, the present GCN5 modulators and their limitations will be presented in a medicinal chemistry perspective.

Qualitative perspectives: through a methodological lens

2014 ◽  
Vol 11 (1) ◽  
pp. 13-28 ◽  
Author(s):  
Lee Parker
Keyword(s):  
Qualitative Research ◽  
Significant Contribution ◽  
Research Literature ◽  
Management Research ◽  
Content Type ◽  
Wide Range ◽  
Qualitative Methodologies ◽  
Insight Into ◽  
Management Scholarship

Purpose – This paper aims to offer an insight into the emergent qualitative methodological profile and its distinctive contribution to accounting and management scholarship, particularly reflecting upon the contribution of Qualitative Research in Accounting & Management (QRAM). Design/methodology/approach – It examines the range of qualitative methodologies employed in the research published across the ten years of QRAM and analyses the methodological discourse and its contribution to the armoury available to qualitative researchers. In association with these methodological developments, the paper offers a critique of the articulated role of theory in contemporary accounting and management qualitative research. Findings – A wide range of qualitative methodologies are found to be in evidence, with considerable scope for further adoption and development of some. Methodological exposition papers are found to be a significant contribution in the past decade and include methodological framework building, methodological applications, methodological critiques, and methodological development exemplars. Alongside methodology, the dual role of theory as either informing or reflecting methodology is presented. Originality/value – The paper provides a critical analysis and consideration of qualitative methodological literature development in the last ten years of accounting and management research literature, particularly reflected in QRAM. It identifies dominant methodologies in use, as well as opportunities for expanding the methodological menu in accounting and management research. Furthermore, it classifies groups of methodological papers and their contributing perspectives, as well as addressing the often-vexed relationship between theory and methodology.

scholarly journals Staphylococcal Enterotoxin C—An Update on SEC Variants, Their Structure and Properties, and Their Role in Foodborne Intoxications

Toxins ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 584
Author(s):  
Danai Etter ◽  
Jenny Schelin ◽  
Markus Schuppler ◽  
Sophia Johler
Keyword(s):  
Dairy Products ◽  
Animal Health ◽  
Food Poisoning ◽  
Structural Features ◽  
Staphylococcal Enterotoxin ◽  
Accessory Gene ◽  
Staphylococcal Enterotoxins ◽  
Accessory Gene Regulator ◽  
Wide Range

Staphylococcal enterotoxins are the most common cause of foodborne intoxications (staphylococcal food poisoning) and cause a wide range of diseases. With at least six variants staphylococcal enterotoxin C (SEC) stands out as particularly diverse amongst the 25 known staphylococcal enterotoxins. Some variants present unique and even host-specific features. Here, we review the role of SEC in human and animal health with a particular focus on its role as a causative agent for foodborne intoxications. We highlight structural features unique to SEC and its variants, particularly, the emetic and superantigen activity, as well as the roles of SEC in mastitis and in dairy products. Information about the genetic organization as well as regulatory mechanisms including the accessory gene regulator and food-related stressors are provided.

scholarly journals Holism and Life Manifestations: Molecular and Space-Time Biology

2010 ◽  
pp. 157-163
Author(s):  
J Křeček
Keyword(s):  
Developmental Stages ◽  
Mutual Recognition ◽  
Space Time ◽  
Limited Attention ◽  
Natural Mode ◽  
Cellular Life ◽  
New Concepts ◽  
Wide Range ◽  
Per Se

Appeals of philosophers to look for new concepts in sciences are being met with a weak response. Limited attention is paid to the relation between synthetic and analytic approach in solving problems of biology. An attempt is presented to open a discussion on a possible role of holism. The term “life manifestations” is used in accordance with phenomenology. Multicellular creatures maintain milieu intérieur to keep an aqueous milieu intracellulair in order to transform the energy of nutrients into the form utilizable for driving cellular life manifestations. Milieu intérieur enables to integrate this kind of manifestations into life manifestations of the whole multicellular creatures. The integration depends on a uniqueness and uniformity of the genome of cells, on their mutual recognition and adherence. The processes of ontogenetic development represent the natural mode of integration of cellular life manifestations. Functional systems of multicellular creatures are being established by organization of integrable cells using a wide range of developmental processes. Starting from the zygote division the new being displays all properties of a whole creature, although its life manifestations vary. Therefore, the whole organism is not only more than its parts, as supposed by holism, but also more than developmental stages of its life manifestations. Implicitly, the units of whole multicellular creature are rather molecular and developmental events than the cells per se. Holism, taking in mind the existence of molecular and space-time biology, could become a guide in looking for a new mode of the combination of analytical and synthetic reasoning in biology.

scholarly journals The Potential Role of REG Family Proteins in Inflammatory and Inflammation-Associated Diseases of the Gastrointestinal Tract

2021 ◽  
Vol 22 (13) ◽  
pp. 7196
Author(s):  
Chao Sun ◽  
Xiaoyu Wang ◽  
Yangyang Hui ◽  
Hirokazu Fukui ◽  
Bangmao Wang ◽  
...  
Keyword(s):  
Potential Role ◽  
Structural Features ◽  
The Body ◽  
Current Evidence ◽  
Gi Tract ◽  
Associated Diseases ◽  
Wide Range ◽  
Colitic Cancer ◽  
Regulatory Effects

Regenerating gene (REG) family proteins serve as multifunctional secretory molecules with trophic, antiapoptotic, anti-inflammatory, antimicrobial and probably immuno-regulatory effects. Since their discovery, accumulating evidence has clarified the potential roles of the REG family in the occurrence, progression and development of a wide range of inflammatory and inflammation-associated diseases of the gastrointestinal (GI) tract. However, significant gaps still exist due to the undefined nature of certain receptors, regulatory signaling pathways and possible interactions among distinct Reg members. In this narrative review, we first describe the structural features, distribution pattern and purported regulatory mechanisms of REG family proteins. Furthermore, we summarize the established and proposed roles of REG proteins in the pathogenesis of various inflammation-associated pathologies of the GI tract and the body as a whole, focusing particularly on carcinogenesis in the ulcerative colitis—colitic cancer sequence and gastric cancer. Finally, the clinical relevance of REG products in the context of diagnosis, treatment and prognostication are also discussed in detail. The current evidence suggests a need to better understanding the versatile roles of Reg family proteins in the pathogenesis of inflammatory-associated diseases, and their broadened future usage as therapeutic targets and prognostic biomarkers is anticipated.

The Problem of Identifying and Modeling the Relationship between Monetary Factor and Inflation in the Russian Economy

2008 ◽  
pp. 61-76
Author(s):  
A. Porshakov ◽  
A. Ponomarenko
Keyword(s):  
Money Supply ◽  
Money Demand ◽  
Russian Economy ◽  
Long Run ◽  
Complex Approach ◽  
Wide Range ◽  
Long Time ◽  
The Relationship ◽  
Supply Side Factors

The role of monetary factor in generating inflationary processes in Russia has stimulated various debates in social and scientific circles for a relatively long time. The authors show that identification of the specificity of relationship between money and inflation requires a complex approach based on statistical modeling and involving a wide range of indicators relevant for the price changes in the economy. As a result a model of inflation for Russia implying the decomposition of inflation dynamics into demand-side and supply-side factors is suggested. The main conclusion drawn is that during the recent years the volume of inflationary pressures in the Russian economy has been determined by the deviation of money supply from money demand, rather than by money supply alone. At the same time, monetary factor has a long-run spread over time impact on inflation.

Introduction: Emotion, History and the Arts

2018 ◽  
Vol 7 (2) ◽  
pp. 117-128 ◽  
Author(s):  
Erin Sullivan ◽  
Marie Louise Herzfeld-Schild
Keyword(s):  
Historical Change ◽  
Carson Mccullers ◽  
Emotional Life ◽  
Review Section ◽  
The Arts ◽  
Wide Range ◽  
War Correspondents ◽  
History Of ◽  
Johan Huizinga

This introduction surveys the rise of the history of emotions as a field and the role of the arts in such developments. Reflecting on the foundational role of the arts in the early emotion-oriented histories of Johan Huizinga and Jacob Burkhardt, as well as the concerns about methodological impressionism that have sometimes arisen in response to such studies, the introduction considers how intensive engagements with the arts can open up new insights into past emotions while still being historically and theoretically rigorous. Drawing on a wide range of emotionally charged art works from different times and places—including the novels of Carson McCullers and Harriet Beecher-Stowe, the private poetry of neo-Confucian Chinese civil servants, the photojournalism of twentieth-century war correspondents, and music from Igor Stravinsky to the Beatles—the introduction proposes five ways in which art in all its forms contributes to emotional life and consequently to emotional histories: first, by incubating deep emotional experiences that contribute to formations of identity; second, by acting as a place for the expression of private or deviant emotions; third, by functioning as a barometer of wider cultural and attitudinal change; fourth, by serving as an engine of momentous historical change; and fifth, by working as a tool for emotional connection across communities, both within specific time periods but also across them. The introduction finishes by outlining how the special issue's five articles and review section address each of these categories, while also illustrating new methodological possibilities for the field.

Short Films from a Small Nation

2018 ◽  
Author(s):  
C. Claire Thomson
Keyword(s):  
Public Information ◽  
Industrial Process ◽  
Actor Network Theory ◽  
Documentary Films ◽  
Wide Range ◽  
Short Films ◽  
Post War ◽  
The 1960S ◽  
Art And Architecture

The first book-length study in English of a national corpus of state-sponsored informational film, this book traces how Danish shorts on topics including social welfare, industry, art and architecture were commissioned, funded, produced and reviewed from the inter-war period to the 1960s. For three decades, state-sponsored short filmmaking educated Danish citizens, promoted Denmark to the world, and shaped the careers of renowned directors like Carl Th. Dreyer. Examining the life cycle of a representative selection of films, and discussing their preservation and mediation in the digital age, this book presents a detailed case study of how informational cinema is shaped by, and indeed shapes, its cultural, political and technological contexts.The book combines close textual analysis of a broad range of films with detailed accounts of their commissioning, production, distribution and reception in Denmark and abroad, drawing on Actor-Network Theory to emphasise the role of a wide range of entities in these processes. It considers a broad range of genres and sub-genres, including industrial process films, public information films, art films, the city symphony, the essay film, and many more. It also maps international networks of informational and documentary films in the post-war period, and explores the role of informational film in Danish cultural and political history.

Moving Beyond Themes

2013 ◽  
Vol 2 (2) ◽  
pp. 213-227 ◽  
Author(s):  
Kristen Lucas ◽  
Suzy D’Enbeau
Keyword(s):  
Qualitative Research ◽  
Research Methods ◽  
Qualitative Research Methods

Teaching novice qualitative researchers how to move beyond first-cycle themes is a challenging endeavor. In this essay, we articulate four harmful habits that tend to impede our success: moving too quickly, privileging product over process, providing cursory coverage of analytic technique and artistry, and overlooking the role of synthesis in qualitative research. As a step toward replacing harmful habits with more healthy ones, we offer a number of practical suggestions for reimagining the qualitative research methods curriculum.

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