scholarly journals Determination of pH as a method of prevention of preterm birth of infectious genesis in women with a history of miscarrage

2015 ◽  
Vol 64 (1) ◽  
pp. 29-33
Author(s):  
Tamara Aleksandrovna Pluzhnikova
Keyword(s):  
Preterm Birth ◽  
Ph Control ◽  
Control Group ◽  
Vaginal Fluid ◽  
Urogenital Infection ◽  
Vaginal Ph ◽  
Fold Reduction ◽  
History Of ◽  
Group 2

There is substantial evidence that urogenital infection is one of the major causes of preterm birth, with bacterial vaginosis being one of these infections. Timely diagnosis and treatment of this condition significantly reduce the rate of preterm birth. The aim of this study was to evaluate the method of pH determination of vaginal fluid in women at a risk of preterm birth. A total of 66 women were included in the study. The women were divided into two groups. Group 1 consisted of 30 women, who measured vaginal pH from week 12 and 36 of gestation twice a week using the test рН-Balance (PremiumDiagnostics, Germany). Group 2 comprised 36 women, who did not measure vaginal pH (control group). Abnormal рН (>4,4) were observed in 9 women (30.0 %). Of them, in 8 women a urogenital infection was observed. All patients received etiotropic treatment. pH measuring in women with a history of miscarriage resulted in 4.5-fold reduction of preterm birth (from 30.0 to 6.7 %). In the control group the was no significant reduction in the rate of preterm birth (from 22.2 to 19.4 %).

scholarly journals Corresponding erdosteine changes autophagy genes expression in hippocampus on Rhinitis medicamentosa model

Genetika ◽  
2015 ◽  
Vol 47 (3) ◽  
pp. 1091-1098
Author(s):  
Recep Dokuyucu ◽  
Bulent Gogebakan ◽  
Cengiz Cevik
Keyword(s):  
Control Group ◽  
Gene Expressions ◽  
Autophagy Gene ◽  
Genes Expression ◽  
Left Hippocampus ◽  
Antioxidant Agent ◽  
Group 3 ◽  
Group 2 ◽  
Rhinitis Medicamentosa

In our study, rats were subjected to Oxymetazoline hydrochloride treatment and Rhinitis medicamentosa (RM) was formed and then autophagy gene expression levels were determined after the application of an antioxidant agent erdosteine (ED). The rats were divided into three groups; Group 1 was the control group. Group 2 (RM) and group 3 (RM+ED) rats received two spray puffs of 0.05% oxymetazoline into the nasal cavities three times daily for eight weeks. After determination of RM in the rats, the RM group were killed. The ED+RM group received 10 mg/kg of an ED suspension. At the end of seven days, these rats were also killed. All groups? hippocampus tissues were obtained for the measurement of autophagy gene expressions. In rhinitis medicamentosa group Atg5, Atg7 and Atg10 gene expressions in the left hippocampus were reduced as compared to control group (p=0.01, p>0.05, p=0.01, respectively). Also, erdosteine treatments were restored mRNA expression of autophagy genes. In right hippocampus of rhinitis medicamentosa group, Atg5 and Atg10 gene expressions was found to be down-regulated as compared to control group (p>0.05, p<0.05, respectively). Both BECN1 and ULK genes expression were found to be reduced in left hippocampus of rhinitis medicamentosa group. Erdosteine applications was restored the expression of these genes (p=0.03, p=0.03, respectively). Additionally, in right hippocampus, Erdosteine application was restored the expression of ULK gene (p=0.01). This is the first report that evaluated the expression autophagy genes in RM rat models and the changes observed after erdosteine applications.

scholarly journals Depression, anxiety levels and sleep quality indexes among the spouses of people with epilepsy

2021 ◽  
Author(s):  
Halil ONDER ◽  
Ersin Kasim ULUSOY ◽  
Caner BAYDAR ◽  
Mustafa KIRAZ ◽  
Muhammet Okay ORUN ◽  
...  
Keyword(s):  
Sleep Quality ◽  
Sleep Disturbances ◽  
Demographic Data ◽  
Cross Sectional Study ◽  
Control Group ◽  
Cross Sectional ◽  
History Of ◽  
Group 3 ◽  
Group 2 ◽  
Psychiatric Problems

ABSTRACT Background: Psychiatric problems and sleep disturbances are comorbidities that are frequently encountered among people with epilepsy. However, their presence among the spouses of peoples with epilepsy remains to be elucidated. Objective: The objective of this study was to evaluate the spouses of people with epilepsy (PWE), with and without a history of seizures during sleep, in terms of depression, anxiety and sleep quality. Methods: This prospective, cross-sectional study was conducted in three groups of 18 to 65-year-olds. Group 1 consisted of healthy spouses of 127 healthy volunteers without any known neurological disease; group 2 comprised spouses of 63 PWE who had no history of seizure during sleep; and group 3 consisted of spouses of 63 PWE who had a history of at least one seizure during sleep in the course of the previous year. Questionnaires seeking demographic data and the Pittsburgh Sleep Quality Index (PSQI), Beck Depression Inventory and Beck Anxiety Inventory were applied to all participants. Results: The depression scores of the group of spouses of PWE were higher than those of the control group and were higher in group 3 than in group 2 (p = 0.017). The anxiety scores of the group of spouses of PWE were significantly higher than those of the control group, but no difference in anxiety scores was found between group 2 and group 3 (p = 0.170). The mean PSQI score of group 3 was higher than that of group 2 (p = 0.029). However, regression analyses did not show any difference between these groups. Conclusion: We found that the PSQI scores, which reflected sleep quality, were higher among the spouses of PWE who had seizures during sleep and who had more severe epilepsy.

Dysregulatory visceropathies in patients with uterine endometriosis and recurrent endometrial hyperplasia

1986 ◽  
Vol 67 (5) ◽  
pp. 347-349
Author(s):  
N. I. Petrushkova
Keyword(s):  
Endometrial Hyperplasia ◽  
Digestive System ◽  
Practical Significance ◽  
Control Group ◽  
Liver And Pancreas ◽  
Rational Therapy ◽  
History Of ◽  
Group 2 ◽  
Digestive Glands ◽  
Group 1

The study of neurohormonal-visceral relationships in patients with uterine endometriosis is of practical significance in the development of rational therapy and prevention of this complex and rather frequent pathology. This study was aimed to investigate the functional state of the digestive glands of the stomach, intestines, liver and pancreas in 152 patients with uterine internal endometriosis (Group 1) and in 50 patients with recurrent endometrial hyperplasia (Group 2). Twenty healthy women were the control group. Patients with no history of diseases of the digestive system were selected for the examination.

Psychiatric Morbidity in Sentenced Segregated HIV-Positive Prisoners

1993 ◽  
Vol 163 (6) ◽  
pp. 802-805 ◽  
Author(s):  
Arthur Dorman ◽  
Art O'Connor ◽  
Eamonn Hardiman ◽  
Aideen Freyne ◽  
Helen O'Neill
Keyword(s):  
Drug Abuse ◽  
Matched Control ◽  
Psychiatric Morbidity ◽  
Hiv Positive ◽  
Control Group ◽  
Matched Control Group ◽  
History Of ◽  
The Mean ◽  
Group 2 ◽  
Group 1

In this comparative study with a control group of prisoners, psychiatric morbidity was measured in two groups of sentenced prisoners, each group completing the GHQ-30 and 21-item Beck Depression Inventory (BDI). Group 1 consisted of 40 segregated HIV-positive prisoners and group 2 a matched control group in the main prison who had no history of HIV seropositivity. All members of group 1 had a history of intravenous drug abuse. The mean GHQ-30 and BDI scores were significantly higher in group 1, and 90% of group 1 were psychiatric ‘cases’ compared with just over 42% of group 2. Levels of psychiatric morbidity present in a third group, consisting of HIV-positive prisoners who had not been segregated (prison authorities were unaware of their seropositivity) are an interesting pointer for further research.

scholarly journals Functional Polymorphisms of Matrix Metalloproteinases 1 and 9 Genes in Women with Spontaneous Preterm Birth

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Nina Pereza ◽  
Ivana Pleša ◽  
Ana Peterlin ◽  
Žiga Jan ◽  
Nataša Tul ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Gene Polymorphisms ◽  
Control Group ◽  
Spontaneous Preterm Birth ◽  
Functional Polymorphisms ◽  
Fetal Birth Weight ◽  
Gestational Age At Delivery ◽  
History Of ◽  
Caucasian Women ◽  
And Control

Objective. The aim of this study was to investigate the association of functionalMMP-1-1607 1G/2G andMMP-9-1562 C/T gene polymorphisms with spontaneous preterm birth (SPTB; preterm birth with intact membranes) in European Caucasian women, as well as the contribution of these polymorphisms to different clinical features of women with SPTB.Methods and Patients. A case-control study was conducted in 113 women with SPTB and 119 women with term delivery (control group). Genotyping ofMMP-1-1607 1G/2G andMMP-9-1562 C/T gene polymorphisms was performed using the combination of polymerase chain reaction and restriction fragment length polymorphism methods.Results. There were no statistically significant differences in the distribution of neither individual nor combinations of genotype and allele frequencies ofMMP-1-1607 1G/2G andMMP-9-1562 C/T polymorphisms between women with SPTB and control women. Additionally, these polymorphisms do not contribute to any of the clinical characteristics of women with SPTB, including positive and negative family history of SPTB, gestational age at delivery, and maternal age at delivery, nor fetal birth weight.Conclusion. We did not find the evidence to support the association ofMMP-1-1607 1G/2G andMMP-9-1562 C/T gene polymorphisms with SPTB in European Caucasian women.

scholarly journals Natural sepiolite efficiency in reducing 137Cs transfer and deposition into meat and edible organs of broiler chickens

2011 ◽  
Vol 27 (2) ◽  
pp. 183-188 ◽  
Author(s):  
D. Vitorovic ◽  
G. Vitorovic ◽  
B. Mitrovic ◽  
V. Andric
Keyword(s):  
Broiler Chickens ◽  
Protective Action ◽  
Total Activity ◽  
Control Group ◽  
Standard Diet ◽  
Percentage Reduction ◽  
Group 2 ◽  
137Cs Deposition ◽  
Group 1

The objectives of the present study were to examine the level of radiocesium deposit in meat and edible organs of broiler chickens as well as to investigate efficiency of natural sepiolite in reducing 137Cs deposition in meat, liver and gizzard of alimentary contaminated broiler chickens. Broiler chickens (six weeks of age) were fed with the standard diet and each broiler was given a single oral dose of 137Cs, total activity of 3750 Bq. The broilers were divided into two groups (10 broilers per group). The group 1 was control (received only radiocesium). The broilers of the group 2, in addition to radiocesium received natural sepiolite solution (2 g sepiolite per bird). After 24 hours, all broilers, from each group, were stunned and killed. The samples of meat, (breast and legs), liver and gizzard were taken from each broiler, for gamma spectrometry determination of radiocesium activity. After 24 hours of contamination, 56 % of introduced 137Cs radioactivity was deposited in the meat (breast and legs muscles), 1 % in the liver and 2,4 % in the gizzard of broiler chickens 42 days of age. Natural sepiolite demonstrated insufficient protective action. Compared to the control group, percentage reduction (decreasing percentage) of 137Cs deposition in meat was 16%, in liver 5% and in gizzard 12%.

scholarly journals Cross-sectional and prospective study on anti-Müllerian hormone changes in a cohort of pre-menopausal women with a history of differentiated thyroid cancer

2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Miranda Mittica ◽  
Andrea Dotto ◽  
Martina Comina ◽  
Marsida Teliti ◽  
Eleonora Monti ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Prospective Study ◽  
Differentiated Thyroid Cancer ◽  
Chronological Age ◽  
Control Group ◽  
Cross Sectional ◽  
Age Related ◽  
History Of ◽  
Group 3 ◽  
Group 2

Abstract Background Anti-Müllerian hormone (AMH) decreases acutely after post-surgical radioactive iodine (RAI) ablation in females with differentiated thyroid cancer (DTC). Aim We performed a cross-sectional and prospective study on AMH levels in pre-menopausal females with a history of DTC. Methods Fifty-nine females after surgery and RAI (group 1) and 30 females after surgery alone (group 2) were studied. The control group consisted of 141 healthy women (group 3). The prospective study was performed in 43 and 14 females from groups 1 and 2, respectively. Results On first evaluation, AMH levels were similar in groups 1 and 2, but lower than in group 3. In all groups, AMH was negatively related with chronological age and FSH levels. When subjects were stratified according to age, AMH levels were not different between groups. When AMH was evaluated up to 2 years after the baseline evaluation, no changes emerged in either group of women with DTC. In the prospective study, the incidence of abnormal menstrual cycles and the onset of menopause were observed in similar percentages of women with a history of RAI-treated DTC and of those treated with surgery alone. Conclusions AMH can be considered a reliable index of ovarian reserve in women with DTC. Chronological age is the main factor influencing AMH levels in both DTC patients and controls. After age-related stratification, AMH levels are similar in women with DTC treated with RAI and those treated with surgery alone.

scholarly journals Flukicide efficacy against Fasciola hepatica of Triclabendazole and Nitroxynil in cattle of the central valley of Chile

2019 ◽  
Vol 28 (1) ◽  
pp. 164-167 ◽  
Author(s):  
Javiera Romero ◽  
Carmen Villaguala ◽  
Fernando Quiroz ◽  
Carlos Landaeta-Aqueveque ◽  
Guillermo Alfaro ◽  
...  
Keyword(s):  
Fasciola Hepatica ◽  
Central Valley ◽  
Oral Route ◽  
Control Group ◽  
Group 4 ◽  
Faecal Egg Count ◽  
History Of ◽  
Group 3 ◽  
Group 2 ◽  
First Time

Abstract On a farm with permanent history of fasciolasis a study was performed aimed to know the efficacy of triclabendazole (TCBZ) and then to contrast with that of nitroxynil. Thirty-nine cattle naturally infected with Fasciola hepatica were randomly allocated into 4 experimental groups: Group 1 (control) was left untreated. Group 2 was treated with of 12 mg/kg body weight (bw) of TCBZ by oral route. Group 3 treated with 24 mg/kg bw TCBZ orally. Group 4 was treated with 10 mg/kg bw of nitroxynil subcutaneously. The anthelmintic efficacy was calculated as the percentage of reduction in faecal egg count (FEC) at 14 and 28 d post-treatment. Results indicated that there were no significant differences in the percentage of FEC reduction between control group and the groups treated with 12 or 24 mg/kg of TCBZ. On the contrary, the treatment with nitroxinyl significantly reduced the FEC and decreased the percentage of positive animals. In conclusion, Fasciola hepatica is reported for first time as resistant to TCBZ in Chile, which highlights the need of rotating drugs and assessing the efficacy of the administered drug in order to avoid the selection of resistant worms.

scholarly journals Chlamydia Trachomatis Infection and Spontaneous Abortion

2021 ◽  
pp. 78-81
Author(s):  
Rahayu Basir ◽  
Eddy Hartono ◽  
Eddy R. Moeljono ◽  
St. Nur Asni
Keyword(s):  
Chlamydia Trachomatis ◽  
Spontaneous Abortion ◽  
Vaginal Discharge ◽  
Study Groups ◽  
Cross Sectional Study ◽  
Control Group ◽  
Cross Sectional ◽  
Chlamydia Trachomatis Infection ◽  
History Of ◽  
Group 2

Abstract Objective: To determine the correlation between spontaneous abortion and Chlamydia trachomatis infection. Methods: A cross-sectional study was conducted in women who experienced spontaneous abortion. Normal pregnancies with gestational age more than equal to 37 weeks as control. Detection of C. trachomatis in the product of conception or placenta from curettage using the PCR method. Results: Positive C. trachomatis was found 3 cases in the abortion group and 4 cases in control. In the abortion group, C. trachomatis found in 1 case with vaginal discharge history and 2 cases without this history. C. trachomatis also found in 3 cases without a history of abortion. This bacteria was not found in patients with an abortion history. In the control group, 2 cases of positive C. trachomatis were found in pregnant women with or without a history of vaginal discharge and abortion, respectively. There were no significant differences regarding the positive of C. trachomatis between the two study groups regarding history of vaginal discharge and abortion. Conclusions: Spontaneous abortion does not correlate with C. trachomatis infection. Keywords: chlamydia trachomatis, infection, spontaneous abortion. Abstrak Tujuan: Untuk mengetahui hubungan antara abortus spontan dan infeksi Chlamydia trachomatis. Metode: Penelitian potong lintang dilakukan pada perempuan yang mengalami abortus spontan. Kehamilan normal dengan usia kehamilan lebih dari sama dengan 37 minggu sebagai kontrol. Deteksi C. trachomatis pada produk konsepsi atau plasenta dari kuretase menggunakan metode PCR. Hasil: C. trachomatis positif ditemukan 3 kasus pada kelompok aborsi dan 4 kasus dalam kontrol. Pada kelompok abortus spontan, C. trachomatis ditemukan pada 1 kasus dengan riwayat keputihan dan 2 kasus tanpa riwayat keputihan. C. trachomatis juga ditemukan pada 3 kasus tanpa riwayat abortus. Bakteri ini tidak ditemukan pada pasien dengan riwayat abortus. Pada kelompok kontrol, 2 kasus positif C. trachomatis masing-masing ditemukan pada perempuan hamil dengan atau tanpa riwayat keputihan dan abortus. Tidak ada perbedaan signifikan C. trachomatis positif antara kedua kelompok penelitian berdasarkan riwayat keputihan dan abortus. Kesimpulan: Abortus spontan tidak berkorelasi dengan infeksi C. trachomatis. Kata kunci: abortus spontan, chlamydia trachomatis, infeksi.

scholarly journals Comparison of different cephalometric variables in patients with and without history of snoring

2017 ◽  
Vol 5 (12) ◽  
pp. 5283
Author(s):  
Azhar Khan ◽  
Mohamad Imran ◽  
Mohammed Imran ◽  
Shoib N. Parkar ◽  
Mueed U. Islam ◽  
...  
Keyword(s):  
Hyoid Bone ◽  
Sleep Apnea Syndrome ◽  
Sleep Apnoea ◽  
Control Group ◽  
Mandibular Plane ◽  
Obstructive Sleep ◽  
High Prevalence ◽  
History Of ◽  
Group 2 ◽  
Group 1

Background: Obstructive sleep apnea syndrome has a high prevalence among adults. Cephalometric variables can be a valuable method for evaluating patients with this syndrome. The objective of this study is to evaluate and compare the craniofacial variables in subjects with and without snoring by cephalometric analysis.Methods: 40 patients were included in the study who were divided into two groups; group 1 of 20 snoring patients and group 2 control group of 20 non-snoring patients and were evaluated and compared for various cephalometric variables.Results: The distance from the hyoid bone to the mandibular plane (MP-H) was the only variable that showed a statistically significant correlation between two groups.Conclusions: Cephalometric variables are useful tools for evaluating the patients with snoring who are predisposed to obstructive sleep apnoea. The distance from the hyoid bone to the mandibular plane showed a statistically significant correlation between two groups.

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