Complement Fluctuations in Protein Therapy for Gonorrhea

1926 ◽  
Vol 22 (4) ◽  
pp. 429-436
Author(s):  
Ya. D. Pechnikov

According to Weichardt, protoplasm activation is at the heart of protein therapy. The result of this activation is an increase in the normal functions of various cellular elements, including those that play a protective role in the body's fight against disease-causing agents. If we can associate the origin of complement and protective immunoids with the functional activity of certain cellular elements, then a priori we can expect an increase in these substances in the body juices under the influence of parenteral administration of foreign proteins.

2020 ◽  
Vol 43 ◽  
Author(s):  
David Spurrett

Abstract Comprehensive accounts of resource-rational attempts to maximise utility shouldn't ignore the demands of constructing utility representations. This can be onerous when, as in humans, there are many rewarding modalities. Another thing best not ignored is the processing demands of making functional activity out of the many degrees of freedom of a body. The target article is almost silent on both.


2005 ◽  
Vol 2005 (3) ◽  
pp. 393-400 ◽  
Author(s):  
Zhi Qian ◽  
Chu-Li Fu ◽  
Xiang-Tuan Xiong

We consider an inverse heat conduction problem (IHCP) in a quarter plane. We want to know the distribution of surface temperature in a body from a measured temperature history at a fixed location inside the body. This is a severely ill-posed problem in the sense that the solution (if exists) does not depend continuously on the data. Eldén (1995) has used a difference method for solving this problem, but he did not obtain the convergence atx=0. In this paper, we gave a logarithmic stability of the approximation solution atx=0under a stronger a priori assumption‖u(0,t)‖p≤Ewithp>1/2. A numerical example shows that the computational effect of this method is satisfactory.


1923 ◽  
Vol 19 (2) ◽  
pp. 94-94
Author(s):  
V. Gruzdev

It is known that some people explain the effect of parenteral administration of proteins by their effect on the parasympathetic system. Salomon, and Oppenheimer hold the view that there is a direct effect on the blood.


2015 ◽  
Vol 12 (1) ◽  
pp. 54-59
Author(s):  
L V Luss

In the pathogenesis of various diseases histamine performs an important role relating to one of the most important mediators involved in the regulation of vital functions in the body. Histamine plays a key role in the development of allergic diseases and pseudoallergic reactions. Therefore, in clinical practice, of particular interest are drugs that block the effects of histamine - antihistamines. The lecture highlights mechanisms of action of histamine and indications for antihistamines. Particular attention is given to parenteral forms of antihistamines and benefits of a new form of antihistamines for parenteral use without sedation - fenkarol one of quinuclidine derivatives. Features and advantages of antihistamines - quinuclidine derivatives, first developed in Laboratory of academician M.D. Mashkovsky are presented.


2019 ◽  
Vol 15 (3) ◽  
pp. 6-25 ◽  
Author(s):  
Krzysztof T. Konecki

I would like to present the possibility of broadening the traditional methodological and technical skills of researcher and analyst, but also the intellectual capacity of the researcher associated with combining data, categorizing, linking categories, as well as the interpretation of the causes and consequences of the emergence of certain social phenomena. Some methodologies, methods, and research techniques are more conducive to creative conceptual and interpretive solutions. Therefore, I describe the serendipity phenomenon in such methodologies as grounded theory, ethnography, phenomenological research, and contemplative inquiry. The problem of intuition in qualitative research will be also described in the paper. There will be presented also some suggestions how to be creative in qualitative research. From the review of issues of creativity in qualitative research we can derive the following conclusions: Creativity in qualitative research depends on the strength of a priori conceptualization and stiffness of the adapted methods of research and analysis. If the methodology is more flexible (as the methodology of grounded theory), the researcher can get to phenomena that he/she has not realized and which are still scantily explored in his/her field of expertise. The phenomenological and contemplative approaches allow the use of the investigator’s feelings and experience as they appear in the studied phenomena, which usually does not take place in objectifying and positivistic research. The investigator may therefore consciously use these methodologies and approaches that foster creativity. The researchers can improve their skills in thinking and creative action by doing some methodical exercises (journal writing, writing poetry as a summary of the collected data, the use of art as representation of the phenomenon, the use of meditation, observation of the body feelings, humor, etc.).


Author(s):  
Daniil Koloskov

In this article, I will pursue three aims. First, I would like to demonstrate the non-transcendental character of Merleau-Ponty’s phenomenology, namely, his claim that a strict division between a priori and a posteriori is an abstraction that derives from a more primordial unity that is given in our lived experience. I will criticize authors such as H. Dreyfus and T. Carman who treat the body and bodily character of our existence as a classical Kantian a priori that functions as a condition of experience without itself being a part of the experience. The claim I would like to defend in this regard is that reflections on the conditions of our experience must themselves be a part of our experience. The second task is to show how Merleau-Ponty’s analysis of temporality helps him to avoid this strict division between a priori and a posteriori. Based on this, I will elucidate some of the most obscure passages of Phenomenology of Perception. Finally, I will claim that the notion of optimal grip can neither be explained by the reference to our body, as Carman claims, or to brains, organisms and their copings with the environment, as Dreyfus argues. Instead, I will claim that the maximal grip is rather a consolidation or intensification of the temporal ecstasy.


2019 ◽  
Vol 1 (4) ◽  
pp. 13-28
Author(s):  
Abdelmonem Awad Hegazy ◽  
Manal Mohammad Morsy ◽  
Rania Said Moawad ◽  
Gehad Mohammad Elsayed

Background Hypothyroidism is a metabolic disorder affecting the functions of many tissues in the body including the testis. Testis is rich in the polyunsaturated fatty acids content and lacks strong intrinsic antioxidant system making it prone to such oxidative stress. L-carnitine (LC) regulates long chain fatty acids metabolism; and is considered a valuable antioxidant factor. Aim It was to evaluate the effect of hypothyroidism induced by propylthiouracil (PTU) on rats’ testes and the possible protective role of LC. Methods Forty-eight adult male albino rats were used in this work. The animals were divided into three groups with sixteen animals in each. Group 1 (Control): Animals were kept without medications. Group 2 (PTU-treated): was subjected to administration of PTU; while group 3 (PTU and LC) received both PTU and LC. By the end of the experiment “30 days”, blood samples were taken for hormonal assay; then animals were anaesthetized and sacrificed. Specimens were homogenized for biochemical analysis; epididymal content of each rat was obtained immediately for semen analysis. Testes’ specimens were harvested, prepared and examined by light microscope examination. Results Induced hypothyroidism was noticed to cause histopathological, morphometric and biochemical changes in rat’s testes. LC protected the testicular specimens against such changes; it also improved the seminal quality and quantity as well as testicular structure and biochemistry. Conclusion Hypothyroidism could result in hazards to the structure of testis. Fortunately co-administration of LC might reduce such hazards.


2018 ◽  
Vol 1 (1) ◽  
pp. 47-53
Author(s):  
Tati Murni Karokaro ◽  
Melisa Queen Hutabarat

In fulfillment of these needs sometimes human forget to maintain their health, good attitude so that the position in work is not ergonomic which can lead to problems when carrying out activities. Lower back pain is a clinical symptom that is characterized by pain or a discomfort feeling in lower back area. In the United States, the incidence of lower back pain region in the past one year is 15% -20%. This study aims to see whether there were differences in giving of Mc Kenzie and Core Stability Exercise toward Functional Activity of Patients with Lower Back Pain. This study is quasi experiment with a sample of patients with lower back pain, with purposive sampling technique. The results obtained are p-value ? <(0,000 <0,05), it means that there is a difference in giving of Mc Kenzie Exercise toward the increase of Functional Activity of Patients with Lower Back Pain, that uses body movements that is directed to extension, to provide strengthening and reflecting on the extensor and flexor muscles of the lumbar joint, while the Core Stability Exercise has the ability to regulate the position and movement in the central region of the body, and it can be concluded that there is differences in Giving of Mc Kenzie Exercise toward the increase of Functional Activity of Patients with Lower Back Pain. It is recommended for patients who experience lower back pain so that keep always repeat the exercises that suggested by physiotherapist, for further research so that choose more samples.


2021 ◽  
pp. 81-87
Author(s):  
N. V. Tuzyuk

Fundamental research in the field of burn wound development process highlights new pathogenetic mechanisms that underlie the improvement of medical practice, the main purpose of which is to create optimal conditions for early regeneration of the affected skin, as well as to eliminate the development of local and general complications. Irrational general and local treatment of wounds contribute to the slowing down of regenerative processes, thereby worsening the prognosis and consequences of thermal injury. It was found out that in patients of both study groups in the first period of the study the characteristics of the cellular composition of the wound impressions of the wound bottom of the area of thermal damage correspond to the degenerative type. In patients of the main group in the second term of the study in the area of thermal damage cells with high levels of functional and metabolic activity begin to appear, which increase antimicrobial resistance and reduce the risk of generalization of the infectious process which is the main source of burns. In patients of the main group, an increase in the activity of neutrophilic granulocytes in the induced test was found in the second term of the study, which, in our opinion, indicates the involvement of neutrophilic granulocytes with high functional and metabolic activity. Under conditions of significant activation of resident monocytes in response to injury in patients of the main group in the second and third term, the area of thermal damage migrates functionally effective monocytes. In patients of the main group the preservation of the activity of myeloperoxidase - the main enzyme of the oxygen-dependent phase of phagocytosis at the minimum subcompensated level, which leads to the preservation of the oxygen-dependent metabolic reaction of neutrophilic granulocytes in the subsequent study, Increases in the content of PAS-positive substances in neutrophilic granulocytes indicate the preservation of the functional reserve for activation and completion of the oxygen-independent phase of phagocytosis. The use of the developed treatment promotes the involvement of functionally active phagocytic cells in the burn wound, reduces the toxic load on monocytes and neutrophils, which helps to maintain their functional activity at the subcompensated level. These trends in patients of the main group reduce the risk of both local and general infectious complications of burn disease. It was found that the level of spontaneous functional activity in the HCT test is associated with the activity of resident monocytes. They form the primary barrier that protects the body from infection or harmful macromolecular complexes. Monocytes - "inflammatory", which constantly come from the free pool and their functional activity against microbial antigens is much higher than resident monocytes. An indicator of the activity of monocytes - "inflammatory" is an indicator of functional activity in the induced HCT test. The results of the study indicate that under conditions of significant activation of resident monocytes in response to injury in patients of the main group in the second and third terms of the area of thermal damage migrate functionally effective monocytes.


Author(s):  
Basarab Nicolescu

A viable education can only be an integral education of the human being. Transdisciplinary education is founded on the inexhaustible richness of the scientific spirit which is based on questioning and of the refusal of all a priori answers and all certitude contradictory to the facts. At the same time, it revalues the role of the deeply rooted intuition, of the imaginary, of sensitivity, and of the body in the transmission of knowledge. It is only in this way that the society of the twenty-first century can reconcile effectivity and respect for the potentiality of every human being. The transdisciplinary approach will be an indispensable complement to the disciplinary approach because it will mean the emergence of continually connected beings, who are able to adapt themselves to the changing exigencies of professional life, and who are endowed with permanent flexibility which is always oriented towards the actualization of their interior potentialities. If the University intends to be a valid actor in sustainable development it has first to recognize the emergence of a new type of knowledge: transdisciplinary knowledge. The new production of knowledge implies a necessary multidimensional opening of the process of learning: towards civil society; towards cyber-space-time; towards the aim of universality; towards a redefinition of the values governing its own existence.


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