On complex treatment and ways of preventing deaths in hemorrhagic fever with renal syndrome

1985 ◽  
Vol 66 (3) ◽  
pp. 186-188
Author(s):  
T. A. Bashkirev

In recent years, the most active natural foci of hemorrhagic fever with renal syndrome (HFRS) have been identified in the regions of the Middle Volga and Ural regions, where more than 70% of registered diseases occur in the RSFSR and a tendency to further growth is observed.

1985 ◽  
Vol 66 (3) ◽  
pp. 174-178
Author(s):  
I. Z. Mukhutdinov ◽  
M. I. Goncharova ◽  
E. M. Gorlovskaya

Observations of the last 20-30 years have revealed a number of new natural foci of hemorrhagic fever with renal syndrome (HFRS) in the Middle Volga region, including the Tatar Autonomous Soviet Socialist Republic.


Author(s):  
Галина Компанец ◽  
Galina Kompanets

This paper includes review of innovative methods of monitoring of activity of natural foci of epidemically important for Russian Federation such viral infections as hemorrhagic fever with renal syndrome (HFRS) and Crimean-Congo hemorrhagic fever (CCHF), and the analysis of probability to control such «exotic» infections, as Denge fever and severe fever with thrombocytopenia syndrome (SFTS).


Author(s):  
N. F. Vasilenko ◽  
A. V. Ermakov ◽  
O. V. Maletskaya ◽  
A. N. Kulichenko

Represented is the analysis of epidemiological situation on vector-borne natural-focal infections in the specially protected eco-resort territory of Russia - Caucasian Mineral Waters of the Stavropol Region. Climactic peculiarities of Caucasian Mineral Waters with their landscape diversity, high abundance rates of ticks and mosquitoes, and anthropogenic impact on ecosystems create favorable conditions for natural foci formation. Crucial epidemiological significance in the regional infectious pathology is attributed to tick-borne borreliosis. Registration of Crimean hemorrhagic fever cases, as well as West Nile (retrospectively) fever and tularemia cases, and identification of specific antibodies to etiological agents of these infections in blood sera of donors testify to volatile epidemiological situation on vector-borne natural-focal infections in the region, which means that there is a need for further ecological, epidemiological and epizootiological monitoring as a constituent element of epidemiological surveillance aimed at provision of sanitary-epidemiological welfare of the population.


2019 ◽  
Vol 13 (5) ◽  
pp. e0007148 ◽  
Author(s):  
Zhaolei Zheng ◽  
Peizhu Wang ◽  
Zhiqiang Wang ◽  
Dandan Zhang ◽  
Xu Wang ◽  
...  

2019 ◽  
Vol 1 (3) ◽  
pp. 105-116
Author(s):  
A. O. Sementsova ◽  
V. G. Dedkov ◽  
V. A. Ternovoy ◽  
E. V. Chub ◽  
S. A. Pyankov ◽  
...  

Ebola virus disease is dangerous viral infection, occurring in the form of hemorrhagic fever, characterized by acute clinical symptoms and high mortality rate due to multiple organ failure. Ebola virus natural foci are located in forested areas of the central and western parts of Africa. It was believed for many years, the incidence of Ebola virus disease has been sporadic and the burden of it is true only in endemic areas. However, the unprecedented Ebola epidemic caused by Zaire virus in 2013 — 2016, has significantly changed our understanding of this disease and the patterns of its distribution. We have also identified weaknesses in the organization of anti-epidemic measures, the effectiveness of which was not very effective at the onset of the epidemic, in particular due to weak development of in vitro diagnostics (IVD). However, during the elimination of the epidemic in West Africa, anti-epidemic system has been modified substantially, largely due to quickly developed IVD kits. This review is devoted to analysis of trends in IVD for Ebola virus disease based on the experience obtained in the course of the West-African epidemic in 2013 — 2016.


Author(s):  
N. V. Volkova ◽  
E. I. Kazachinskaya ◽  
D. N. Shcherbakov

Marburg fever is an acute natural-focal disease characterized by severe course, hemorrhagic syndrome, high level of contagiousness and lethality. The causative agent of the disease is the RNA-containing virus belonging to the family of filoviruses (Filoviridae). The main problem faced by doctors and scientists involved in the fight against Marburg fever is the lack of vaccines and preventive drugs against this disease. The development of effective vaccines against filovirus infection is relevant for protecting the population living in natural foci and medical personnel during epidemic outbreaks, as well as for ensuring safe research work in BSL-4 laboratories. In this regard, this review considers biomodels suitable for studying the pathogenesis of filovirus infections, preclinical studies of specific activity and harmlessness of prototype Marburg virus vaccines and variants of these vaccines.


Author(s):  
V. N. Chekashov ◽  
K. S. Zakharov ◽  
Sh. V. Magerramov ◽  
A. G. Selenina ◽  
K. S. Martsokha ◽  
...  

Hemorrhagic fever with renal syndrome (HFRS) is classifed as a most widely spread natural-focal zoonotic infection in the forest and forest-steppe regions of Russia, taking a leading position by the incidence rate among the population. The Saratov region is enzootic as regards to HFRS, but it is not included in the list of constituent entities characterized by sustainably high morbidity rates. In some years, given favorable ecological conditions, explosive growth in the numbers of the red vole (the main carrier of Hantavirus) is registered, which leads to epidemic complications. In the winter 2018– 2019season, an intensive subniveal breeding of the red vole occurred, which led to an increase in the numbers of the species in the spring. The density of such animals increased, they began to spread widely across the territory. Intensive and extensive epizooties in rodent settlements developed in the natural foci of HFRS. This was especially evident in the territory of the forest park zone “Kumysnaya Polyana”, located in the vicinity of the regional center. The numbers of rodents in ravine and floodplain deciduous forests increased everywhere and amounted to 37.6% in spring and 53.7% in autumn per 100 capture gears, which was 1.6–2 times higher than the average long-term level. The index of dominance of the red vole has also doubled and amounted to 69.5%. In general, the infection rate of rodents increased by 2-3 times in the region. This indicator in the territory of the Saratov forest park was 20.6% in spring and 35.3% in autumn. Against this background, a record outbreak of HFRS was registered in 2019, namely, 109.7 cases per 100 thousand of the population, which was ten times higher than the long-term indicator (7.2). The results of this research should be taken into account when organizing and conducting epizootiological monitoring and preventive measures in the natural foci of HFRS and other zoonotic infections.


1985 ◽  
Vol 66 (3) ◽  
pp. 240-240
Author(s):  
T. A. Bashkirev

Hemorrhagic fever with renal syndrome is a common natural focal disease that is often severe and fatal. Aggravating factors are errors in diagnosis, late hospitalization of patients, multiple transfers from one hospital to another, incorrect or delayed treatment.


Author(s):  
A. Yu. Popova ◽  
A. N. Kulichenko ◽  
O. V. Maletskaya ◽  
N. F. Vasilenko ◽  
L. I. Shaposhnikova ◽  
...  

Aim. Analysis of epidemic manifestations of natural-foci infections (NFI), clarification of spectrum of their causative agents, determination of epizootic activity of natural foci in the Crimea Federal District (KFD). Materials and methods. Epizootologic examination of 10 administrative districts of KDF was carried out. 291 pools (2705 specimens) of ixodes ticks and 283 samples of organs of small mammals were studied by PCR method for the presence of DNA/RNA of causative agents of a number of NFI. Results. Morbidity by NFI in KFD was registered by 6 nosologies: Lyme borreliosis, Marseilles fever, leptospirosis, tularemia, intestine yersiniosis and tick-borne viral encephalitis, wherein, transmissive infections made up 91.6%. Circulation of causative agents of Crimea hemorrhagic fever, Q fever, group of tick-borne spotted fever, Lyme borreliosis, human granulocytic anaplasmosis, human monocytic ehrlichiosis, hemorrhagic fever with renal syndrome, West Nile fever, tularemia and leptospirosis was established. Conclusion. Due to activity of natural foci of NFI further monitoring of epidemiologic and epizootologic manifestations of these infections in the Crimea, including using genetic methods of analysis, is necessary for ensuring sanitary-epidemiologic welfare of KFD population.


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