scholarly journals Prevalence of atopic dermatitis symptoms and its relation to respiratory allergy in preadolescent children

2013 ◽  
Vol 94 (1) ◽  
pp. 55-59
Author(s):  
B A Shamov ◽  
I G Safiullina ◽  
A B Beshimova
Keyword(s):  
Atopic Dermatitis ◽  
Bronchial Asthma ◽  
Questionnaire Survey ◽  
International Study ◽  
The Past ◽  
Asthma Symptoms ◽  
Preadolescent Children ◽  
Strong Relation ◽  
Asthma And Allergy ◽  
Set Up

Aim. To study the prevalence of atopic dermatitis symptoms and its relation to bronchial asthma symptoms in children of 7-8 years of age. Methods. 8880 children aged 7-8 years were examined (3000 children - in 2002, 2865 children - in 2006, 3015 children - in 2010). A questionnaire survey for atopic dermatitis symptoms was conducted as a part of international unified program «International Study of Asthma and Allergy in childhood». Results. Significant differences in prevalence of atopic dermatitis symptoms according to the questionnaire survey and as documented in medical charts were determined. The prevalence of atopic dermatitis symptoms has raised from 12.5±0.4% in 2002 to 20.4±1.5% in 2010 (р 0.001). The prevalence of atopic dermatitis symptoms early onset (younger than 2 years of age) decreased from 7.6±1.0 to 4.9±0.8% (p 0.05). The prevalence of atopic dermatitis relapses during the past calendar year increased from 3.2±0.6 to 4.8±0.8% (p 0.05). Meanwhile, the diagnosis of atopic dermatitis was set up in preadolescent children 7-8 years of age fore frequently: to 4.0±0.7% in 2002 compared to 13.8±1.3% in 2010 (p 0.001). The prevalence of atopic dermatitis and bronchial asthma combination increased from 3.4±0.4 to 7.8±1.0% (p 0.001). A strong relation between presence of atopic dermatitis symptoms and bronchial asthma symptoms was discovered (from 0.76 to 1.00, p 0.05). Conclusion. The prevalence of atopic dermatitis symptoms and bronchial asthma symptoms is still growing in preadolescent children 7-8 years of age, a relation between presence of abovementioned diseases symptoms was discovered.

scholarly journals Preschool Asthma Symptoms in Children Born Preterm: The Relevance of Lung Function in Infancy

2020 ◽  
Vol 9 (10) ◽  
pp. 3345
Author(s):  
Manuel Sanchez-Solis ◽  
Maria Soledad Parra-Carrillo ◽  
Pedro Mondejar-Lopez ◽  
Patricia W Garcia-Marcos ◽  
Luis Garcia-Marcos
Keyword(s):  
Lung Function ◽  
Hospital Admissions ◽  
International Study ◽  
School Age ◽  
Lung Function Tests ◽  
The Core ◽  
The Past ◽  
Asthma Symptoms ◽  
Asthma And Allergy ◽  
Preterm Newborns

Background: The aim of the study is to assess whether lung function of infants born preterm predicts wheezing in pre-school age. Methods: A survey of the core wheezing questionnaire of the International Study on Asthma and Allergy in Children was administered to parents of preterm newborns, to whom lung function tests were performed at a corrected age of six months, and who, at the time of the survey, were between three and nine years of age. Results: Low values of all lung function parameters measured, except FVC, were predictors of wheezing at some time in life, (FEV0.5 OR: 0.62 (95%CI 0.39; 0.995); FEV0.5/FVC OR: 0.73 (0.54; 0.99)) FEF75 OR: 0.60 [0.37; 0.93]; FEF25-75 OR: 0.57 (0.37; 0.89)); and of wheezing in the past year (FEV0.5 OR: 0.36 (0.17; 0.76); FEV0.5/FVC OR: 0.59 (0.38; 0.93); FEF75 OR: 0.38 [0.19; 0.76]; FEF25-75 OR: 0.35 (0.17; 0.70). In addition, FEV0.5/FVC values lower than the lowest limit of normality, were predictive of hospital admissions due to wheezing (OR: 3.07; (1.02; 9.25)). Conclusions: Limited lung function in infancy is predictive of both future wheezing and hospitalization for a wheezing episode.

scholarly journals PREVALENCE OF ALLERGIC DISEASES SYMPTOMS AMONG CHILDREN OF THE GRODNO REGION (REPUBLIC OF BELARUS)

2014 ◽  
Vol 11 (5) ◽  
pp. 46-50
Author(s):  
R N Khokha
Keyword(s):  
Allergic Rhinitis ◽  
Atopic Dermatitis ◽  
Bronchial Asthma ◽  
International Study ◽  
Allergic Diseases ◽  
School Students ◽  
Russian Version ◽  
Childhood Program ◽  
Asthma And Allergy

Background. To study the prevalence of symptoms of allergic diseases among school students of the Grodno region (Republic of Belarus). Methods. Researches conducted a questioning method by means of the Russian version of the standardized «International Study of Asthma and Allergy in Childhood» program (ISAAC). Results. Results of questioning of 1787 schoolchildren showed that the wheezing, within the last 12 months was registered in 9,3% of children of the first classes (DI: 7,5-11,5%) and in 9,1% of children of the eighth classes (DI: 7,5-11%), rhinitis symptoms without cold or flu - in 29,7% of children of the first classes (DI: 26,7-32,85%) and in 47,2% of children of the eighth classes (DI: 44-50%), symptoms of atopic dermatitis - in 8,2% of children of the first classes (DI: 6,6-10%) and in 1,9% of children of the eighth classes (DI: 1-2,97%). Frequency of clinically verified diagnosis of bronchial asthma at schoolchildren at the age of 6-7 y.o. and at the age of 13-14 y.o. was 3,9% (DI: 3-4,9%), allergic rhinitis - 5,6% (DI: 4,6-6,8%), atopic dermatitis - 6,2% (DI: 5,2-7%). Conclusion. Results of the study confirm the need of carrying out further epidemiological researches for the purpose of earlier identification of patients with allergic diseases.

Atopic dermatitis: new horizons of therapy

2019 ◽  
Vol 1 (7) ◽  
pp. 29-32 ◽  
Author(s):  
L. S. Kruglova ◽  
E. M. Gensler
Keyword(s):  
Blood Pressure ◽  
Immune Response ◽  
Allergic Rhinitis ◽  
Atopic Dermatitis ◽  
Targeted Therapy ◽  
Inflammatory Response ◽  
Bronchial Asthma ◽  
New Horizons ◽  
The Past

Over the past decades, the first breakthrough milestone in the treatment of severe forms of atopic dermatitis (AD) has been targeted therapy aimed at inhibiting IL-4 and IL-13. This was made possible thanks to advances in the understanding of the pathogenesis of AD, the driver of which is the Th2-type immune response, which also underlies such manifestations of atopy as bronchial asthma, allergic rhinitis, and polynosis. In the case of the Th2-type immune response, cytokines IL-4 and IL-13 are secreted, which are the main promoters of the inflammatory response in AD. Inhibition of IL-4 and IL-13 leads to the prevention of inflammation and is an effective approach to therapy. The use of therapy aimed at inhibition of cytokines allows you to effectively cope with the manifestations of severe and moderately severe blood pressure.

scholarly journals Biological drugs in the therapy of atopic dermatitis and bronchial asthma: focus on dupilumab

2021 ◽  
pp. 129-137
Author(s):  
Vera A. Reviakina ◽  
Natalia A. Geppe ◽  
Aleksandr B. Malakhov ◽  
Oleg V. Kaliuzhin ◽  
Natalia G. Astaf'eva ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Targeted Therapy ◽  
Bronchial Asthma ◽  
Inflammatory Disease ◽  
Clinical Case ◽  
Allergic Diseases ◽  
Significant Progress ◽  
Biological Drugs ◽  
The Past

Significant progress has been made over the past decade in the treatment of allergic diseases such as atopic dermatitis and bronchial asthma. Dupilumab, which targets interleukin IL-4 and IL-13, has become an innovative targeted therapy. Immunobiologic therapy with the interleukin inhibitor is indicated for patients with moderate to severe uncontrolled atopic dermatitis, moderate to severe eosinophilic phenotype of uncontrolled Bronchial asthma and patients with poorly controlled severe chronic polyposis rhinosinusitis. A clinical case and recent data on the use of dupilumab for the treatment of type 2 inflammatory disease and prospects for its use are discussed.

scholarly journals Allergic march in children of Ukraine

2021 ◽  
Vol 26 (4) ◽  
pp. 181-188
Author(s):  
О.P. Volosovets  ◽  
Yu.K. Bolbot ◽  
G.V. Beketova ◽  
V.S. Berezenko ◽  
T.R. Umanets ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Atopic Dermatitis ◽  
Bronchial Asthma ◽  
Allergic Diseases ◽  
School Age Children ◽  
Steady Increase ◽  
The Past ◽  
Number Of Factors ◽  
Allergic March ◽  
Analyze Data

Allergic diseases, which have a certain stage in their development from food allergy to bronchial asthma / allergic rhinitis, are much more common in children than in adults. The aim of this study was to analyze data on the prevalence and incidence of atopic dermatitis, bronchial asthma and allergic rhinitis as components of the allergic march, in children of Ukraine from 1994 to 2017 to determine the possible impact of adverse environmental factors on their development. During the same period, due to the influence of a number of factors, in particular environmental, there were significant changes in the structure of allergic diseases making up the stages of the allergic march due to an increase in the proportion of allergic rhinitis with the reduced one of asthma and atopic dermatitis. Within 24 years, the incidence of atopic dermatitis in children aged 0-6 years including, increased by 27.6%, in adolescents - by 40.5% and significantly decreased by 39.5% in children aged 7-14 years including. Most cases of allergic rhinitis and bronchial asthma were observed in schoolchildren (47.6 and 54.0%, respectively) with a slight decrease compared to 1994. In general, allergic diseases in recent years have become more common in children from 0 to 6 years and their detection has decreased in school-age children and adolescents. Over the past 24 years, in children of Ukraine a steady increase in the incidence and prevalence of allergic diseases that form an allergic march has been noted: the prevalence of bronchial asthma has increased by 69.3% and the incidence has increased by 22.9%; the prevalence of atopic dermatitis increased by 43.9% and the incidence increased by 8.3%; the prevalence of allergic rhinitis increased by 488.3% and the incidence of allergic rhinitis increased by 380.3%, with a predominance of detection of this pathology in children from regions with developed infrastructure and industry, where there are significant emissions of pollutants into the atmosphere, that have a direct moderate effect on the increase in the prevalence of bronchial asthma, the incidence and prevalence of allergic rhinitis in children.

scholarly journals Prevalence of bronchial asthma, allergic rhinitis, atopic dermatitis in children in Lesnoy area of Sverdlovsk region

2012 ◽  
Vol 9 (3) ◽  
pp. 14-17
Author(s):  
N A Volkova ◽  
E K Beltyukov
Keyword(s):  
Allergic Rhinitis ◽  
Atopic Dermatitis ◽  
Bronchial Asthma ◽  
Age Groups ◽  
International Study ◽  
Allergic Diseases ◽  
Preschool Age ◽  
Atopic Diseases ◽  
Younger Age ◽  
Further Development

A research of prevalence of allergic diseases in children from 0 to 6 years has been carried out using a standardized program «International Study of Asthma and Allergies in Childhood» (ISAAC) in town Lesnoy in 2010. Background. To define the prevalence and structure of atopic diseases in different age groups in children of preschool age in town Lesnoy. Methods. Standardized program «International Study of Asthma and Allergies in Childhood» (ISAAC). Results. Formation of atopic march is defined, in early age — atopic dermatitis and later respiratory form of allergy. Conclusion. Treatment of atopic dermatitis as risk factor of further development of allergic rhinitis and bronchial asthma can promote preventive maintenance of respiratory forms of allergy in children of younger age.

scholarly journals Time trends in the prevalence of asthma and allergy among 6–7-year-old children. Results from ISAAC phase I and III studies in Kaunas, Lithuania

Medicina ◽  
2008 ◽  
Vol 44 (12) ◽  
pp. 944 ◽  
Author(s):  
Jolanta Kudzytė ◽  
Eugenijus Griška ◽  
Jurgis Bojarskas
Keyword(s):  
Allergic Rhinitis ◽  
Atopic Dermatitis ◽  
Primary Schools ◽  
International Study ◽  
Allergic Diseases ◽  
Cross Sectional ◽  
School Based ◽  
Study Population ◽  
Asthma And Allergy ◽  
Core Questionnaire

Objective. To assess the changes in the prevalence of asthma and allergy in 6–7- year-old schoolchildren in Kaunas, Lithuania, using the International Study of Asthma and Allergy in Childhood (ISAAC) core questionnaire. Material and methods. Two cross-sectional surveys (1994/1995–2001/2002) according to the ISAAC protocol were carried out. Lithuanian version of the ISAAC core questionnaire was completed by parents randomly selected from Kaunas primary schools. A school-based sample of 1879 participants in the 1994/1995 survey and 2772 participants in the 2001/2002 survey was study population. Results. The response rates in 1994 and 2002 were 93.95% and 92.4%, respectively. There is a tendency towards an increase in the prevalence of current symptoms and diagnoses for all three conditions, but it was more pronounced in boys. Significant increases in the prevalence of asthma (0.9% vs 2.6%), allergic rhinitis (1.4% vs 2.4%), and atopic dermatitis (1.4% vs 3.5%) were observed comparing two surveys. Still a lot of allergic diseases remain undiagnosed. Conclusions. Our study shows that the prevalence of symptoms of asthma, allergic rhinitis, and atopic dermatitis is increasing, reflecting the changes in morbidity from these conditions in our country.

scholarly journals Questionnaire Survey of Possible Association of Allergic Diseases with Adverse Reactions to SARS-CoV-2 Vaccination

Vaccines ◽  
2021 ◽  
Vol 9 (12) ◽  
pp. 1421
Author(s):  
Hiroki Morimoto ◽  
Satoshi Hayano ◽  
Naoya Ozawa ◽  
Yasuaki Ogura ◽  
Hiroaki Usui ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Adverse Effects ◽  
Bronchial Asthma ◽  
Questionnaire Survey ◽  
Joint Pain ◽  
Allergic Diseases ◽  
Skin Reactions ◽  
Local Skin ◽  
Systemic Reactions

To protect against COVID-19, SARS-CoV-2 vaccines have been widely used. Besides anaphylaxis, some less severe adverse effects may occur at higher frequencies. It remains unclear whether present or past histories of allergic diseases exert effects on local and systemic reactions. We conducted a questionnaire survey among workers in our hospital. We analyzed the adverse effects occurring after the first and second doses of the Pfizer–BioNTech vaccine in 955 subjects. The presence or absence of local injection reactions and systemic reactions (headache, fatigability, fever, muscle pain, and joint pain) was questioned. The intensities of these reactions were graded on a scale of 0–4 (except fever) or 0–2 (fever). The allergic diseases that we focused on were bronchial asthma, atopic dermatitis, food allergy, pollinosis, and hand eczema. For the systemic reactions, fatigability after the first dose tended to be more severe in the bronchial asthma than in the non-allergic group. Headache, joint pain, and fever tended to be more severe in the food allergy than in the non-allergic group after the second dose. For the local skin reactions, atopic dermatitis subjects tended to show rather less severe local skin reactions after the second dose. The results contribute to the guidelines for the care of individuals with different allergy histories, so that they may safely receive their vaccine.

How biotechnology companies respond to bioethical issues

10.5912/jcb22 ◽  
1969 ◽  
Vol 9 (2) ◽  
Author(s):  
Makina Kato ◽  
Darryl Macer
Keyword(s):  
North America ◽  
Questionnaire Survey ◽  
Ethics Committees ◽  
International Organisations ◽  
The Public ◽  
The Past ◽  
Bioethical Issues ◽  
Biotechnology Companies ◽  
The Media ◽  
Set Up

This paper presents the main findings of a research project that investigated how biotechnology companies in different countries address bioethical issues. The study comprised a questionnaire survey and a series of interviews with international organisations and academics in Japan, Europe and North America. While the research clearly indicated that a number of companies expected to have to address bioethical issues in the future, the results also demonstrated that there was a hesitance to admit that bioethical issues had caused problems in the past. The findings also established that companies responded to bioethical issues in different ways and some of the larger organisations were found to set up ethics committees and educate their employees more effectively on bioethical issues. The respondents were also concerned by the biased or distorted view provided by the media and felt it was important that objective information on this area was provided to the public.

Sign in / Sign up

Export Citation Format

Share Document