scholarly journals Psychotherapy, psychoanalysis and anthropology: how a psychiatrist becomes a sophist (commentary to Joseph Zislin, md, part 1)

2021 ◽  
Vol LIII (1) ◽  
pp. 41-47
Author(s):  
Innokentiy A. Martynov
Keyword(s):  
Clinical Practice ◽  
Social Studies ◽  
Academic Writing ◽  
Fairy Tales ◽  
Clinical Medicine ◽  
Academic Field ◽  
Conscious Decision ◽  
Problematic Issue ◽  
Logical Fallacies ◽  
Present Text

How and why psychoanalysts become storytellers is a two-part article by Joseph Zislin, MD published by the Neurology Bulletin in 2020. In this paper Dr. Zislin studies several quasi-psychoanalytical essays on famous fairy-tales, published by physicians and psychologists online. Surprisingly, it is from his own philological discussion of their texts which Dr. Zislin draws conclusions about therapeutic abilities of the authors, as well as about the relevance of psychoanalysis to clinical practice and social studies alike. The present text is a commentary to Dr. Zislins How and why psychoanalysts become storytellers. It studies the ways of gathering and presenting data exercised in the original paper, as well as the strategies of argumentation Dr. Zislin chooses. Although one cannot tell for sure whether the data presented were distorted on purpose or not, choosing the strategy of argumentation is always a more or less conscious decision. Some analytic tools of rhetoric allow one to demonstrate that Dr. Zislin uses argumentation unacceptable in academic writing that of deceptive reasoning, logical fallacies and sophisms. The present commentary is to highlight a problematic issue: should a practicing physician adhere to rules and norms of other disciplines, once he goes beyond the strict academic field of clinical medicine?

scholarly journals eMED-DNA: An in silico operating system for clinical medical data storage within the human genome

2019 ◽  
Author(s):  
Md. Jakaria ◽  
Kowshika Sarker ◽  
Mostofa Rafid Uddin ◽  
Md. Mohaiminul Islam ◽  
Trisha Das ◽  
...  
Keyword(s):  
Operating System ◽  
Clinical Practice ◽  
Data Storage ◽  
Real World ◽  
In Silico ◽  
Clinical Medicine ◽  
Genomic Medicine ◽  
Integrative System ◽  
A Genome ◽  
Storage Technologies

AbstractThe propitious developments in molecular biology and next generation sequencing have enabled the possibility for DNA storage technologies. However, the full application and power of our genomic revolution have not been fully utilized in clinical medicine given a lack of transition from research to real world clinical practice. This has identified an increasing need for an operating system which allows for the transition from research to clinical use. We present eMED-DNA, an in silico operating system for archiving and managing all forms of electronic health records (EHRs) within one’s own copy of the sequenced genome to aid in the application and integration of genomic medicine within real world clinical practice. We incorporated an efficient and sophisticated in-DNA file management system for the lossless management of EHRs within a genome. This represents the first in silico integrative system which would bring closer the utopian ideal for integrating genotypic data with phenotypic clinical data for future medical practice.

scholarly journals Minimal/measurable residual disease in AML: a consensus document from the European LeukemiaNet MRD Working Party

Blood ◽  
2018 ◽  
Vol 131 (12) ◽  
pp. 1275-1291 ◽  
Author(s):  
Gerrit J. Schuurhuis ◽  
Michael Heuser ◽  
Sylvie Freeman ◽  
Marie-Christine Béné ◽  
Francesco Buccisano ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Clinical Medicine ◽  
Residual Disease ◽  
Working Party ◽  
Prognostic Indicator ◽  
The United States ◽  
Molecular Data ◽  
Multiparameter Flow Cytometry ◽  
Consensus Document ◽  
Measurable Residual Disease

Abstract Measurable residual disease (MRD; previously termed minimal residual disease) is an independent, postdiagnosis, prognostic indicator in acute myeloid leukemia (AML) that is important for risk stratification and treatment planning, in conjunction with other well-established clinical, cytogenetic, and molecular data assessed at diagnosis. MRD can be evaluated using a variety of multiparameter flow cytometry and molecular protocols, but, to date, these approaches have not been qualitatively or quantitatively standardized, making their use in clinical practice challenging. The objective of this work was to identify key clinical and scientific issues in the measurement and application of MRD in AML, to achieve consensus on these issues, and to provide guidelines for the current and future use of MRD in clinical practice. The work was accomplished over 2 years, during 4 meetings by a specially designated MRD Working Party of the European LeukemiaNet. The group included 24 faculty with expertise in AML hematopathology, molecular diagnostics, clinical trials, and clinical medicine, from 19 institutions in Europe and the United States.

scholarly journals COMPREHENSIVE ASSESSMENT OF COMBORIDITY IN CLINICAL PRACTICE: METHODICAL APPROACHES AND PRACTICAL USE

2021 ◽  
Vol 2 (16) ◽  
pp. 32-38
Author(s):  
G.Z. Moroz ◽  
I.M. Hidzynska ◽  
T.S. Lasytsia
Keyword(s):  
Clinical Practice ◽  
Coronary Artery ◽  
Medical Records ◽  
Charlson Comorbidity Index ◽  
Clinical Medicine ◽  
Myocardial Revascularization ◽  
State Institution ◽  
Comprehensive Assessment ◽  
Coronary Artery Stenting ◽  
Comorbidity Index

Aim: to evaluate current approaches to the assessment of comorbidity in clinical practice and determine the prevalence of comorbidities in patients with coronary artery disease (CAD) who underwent coronary artery stenting. Material and methods. We performed a retrospective analysis of data from electronic medical records of 150 CAD patients below 75 yrs having undergone myocardial revascularization via percutaneous coronary intervention (coronary artery stenting). All of them were under the monitoring of the cardiologists of the State Institution of Science «Research and Practical Center of Preventive and Clinical Medicine” State Administrative Department. Comorbidity assessment was performed via diseases count; we have dealt only with diseases that are included in the Charlson Comorbidity Index (ССІ) and Combined Age Charlson Comorbidity Index (СА-ССІ) calculation proceeding. We used statistical software programs (Statistica v. 6.0) and Microsoft Excel 2007 applications for data analysis. Results. According to data of the medical records the most common comorbidities (among those used to calculate CCI and CA-CCI) in patients with CAD below 75 yrs who underwent coronary artery stenting were cerebrovascular disease (83.3 ± 3.0%), peripheral vascular diseases (42,7±4,0%), type 2 diabetes mellitus, and mild liver diseases (24,0±3,6%). It was found that the number of comorbid diseases in patients having been examined ranged from 2 to 7, with an average of 3,9±0,1. The mean number of diseases in patients of different ages did not differ significantly. The average CA-CCI value increased from 4,4±0,2 points in patients who had two diseases to 12,7±1,1 points in those with seven ones (р<0,05). Conclusions. Our study revealed a high prevalence of comorbidities in patients with CAD below 75 yrs who underwent coronary artery stenting. The use of CA-CCI allowed making a comprehensive assessment of patient’s conditions

scholarly journals Endothelial glycocalyx in acute care surgery – what anaesthesiologists need to know for clinical practice

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
David Astapenko ◽  
Jan Benes ◽  
Jiri Pouska ◽  
Christian Lehmann ◽  
Sufia Islam ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Acute Care ◽  
Fluid Therapy ◽  
Clinical Medicine ◽  
Specific Treatment ◽  
Endothelial Glycocalyx ◽  
Acute Care Surgery ◽  
Apical Surface ◽  
Important Principle ◽  
Care Surgery

AbstractThe endothelial glycocalyx (EG) is the thin sugar-based lining on the apical surface of endothelial cells. It has been linked to the physiological functioning of the microcirculation and has been found to be damaged in critical illness and after acute care surgery. This review aims to describe the role of EG in severely injured patients undergoing surgery, discuss specific situations (e.G. major trauma, hemorrhagic shock, trauma induced coagulopathy) as well as specific interventions commonly applied in these patients (e.g. fluid therapy, transfusion) and specific drugs related to perioperative medicine with regard to their impact on EG.EG in acute care surgery is exposed to damage due to tissue trauma, inflammation, oxidative stress and inadequate fluid therapy. Even though some interventions (transfusion of plasma, human serum albumin, hydrocortisone, sevoflurane) are described as potentially EG protective there is still no specific treatment for EG protection and recovery in clinical medicine.The most important principle to be adopted in routine clinical practice at present is to acknowledge the fragile structure of the EG and avoid further damage which is potentially related to worsened clinical outcome.

A Corpus-based Analysis of Phrasal Complexity across Different Sections of Research Articles in two Academic Disciplines

2020 ◽  
Author(s):  
Rajab Esfandiari ◽  
Mohammad Ahmadi
Keyword(s):  
Noun Phrase ◽  
Academic Writing ◽  
Clinical Medicine ◽  
Applied Linguistics ◽  
Writing Development ◽  
Academic Disciplines ◽  
Research Articles ◽  
Distributional Pattern ◽  
Complexity Measures ◽  
Leading Journals

Abstract Complexity measures in academic writing have experienced a shift from clausal to phrasal indices in recent years. Drawing on a subset of Biber et al. (2011) hypothesized stages of writing development, we explored phrasal complexity across sections of research articles (RAs) in applied linguistics and clinical medicine. A 389,332-word corpus consisting of 80 randomly selected RAs from leading journals in applied linguistics and clinical medicine was compiled for the purposes of the present study. One-way analysis of variance (ANOVA) and independent-samples t-test, as implemented in SPSS (version 25), were employed to find differences across the RA sections and between two groups of academic writers. The findings indicated that RAs in clinical medicine relied more heavily on noun phrase modifiers in all sections than those in applied linguistics, suggesting that the distributional pattern of these linguistic expressions is discipline-independent. The implications of the findings are also discussed.

Acid Base Physiology In Medicine: A Self-Instruction Program, by Robert W. Winters, M.D., Knud Engel, Mag.Sc., and Ralph B. Dell, M.D., and programmed by Richard P. Berkson, A.B. Westlake, Ohio: The London Company, 1967, 290 pp., $3.85

PEDIATRICS ◽  
1968 ◽  
Vol 42 (4) ◽  
pp. 717-717
Author(s):  
Michael James Sweeney
Keyword(s):  
Clinical Medicine ◽  
Senior Author ◽  
Programmed Instruction ◽  
Acid Base Balance ◽  
Acid Base ◽  
Educational Effort ◽  
Base Balance ◽  
Self Instruction ◽  
Present Text

For some years, the senior author of this book and his associates have contributed much to our understanding of the physiologic aspects of acid-base balance. The present text represents major educational effort on their part to offer a "systematic presentation of acid-base physiology in the format of programmed instruction." The primary audience the book is directed toward are those who already have the "feel" of clinical medicine and who desire "an integrated picture of acid-base physiology as a background for their clinical activities."

scholarly journals Gold Nanoparticles: A New Golden Era in Oncology?

2020 ◽  
Vol 13 (8) ◽  
pp. 192 ◽  
Author(s):  
Clara Gerosa ◽  
Guido Crisponi ◽  
Valeria Marina Nurchi ◽  
Luca Saba ◽  
Rosita Cappai ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Clinical Practice ◽  
Anticancer Agents ◽  
High Selectivity ◽  
Clinical Medicine ◽  
Therapeutic Agents ◽  
Therapeutic Strategies ◽  
Therapeutic Approaches ◽  
Starting Point ◽  
Low Toxicity

In recent years, the spectrum of possible applications of gold in diagnostics and therapeutic approaches in clinical practice has changed significantly, becoming surprisingly broad. Nowadays, gold-based therapeutic agents are used in the therapy of multiple human diseases, ranging from degenerative to infectious diseases and, in particular, to cancer. At the basis of these performances of gold, there is the development of new gold-based nanoparticles, characterized by a promising risk/benefit ratio that favors their introduction in clinical trials. Gold nanoparticles appear as attractive elements in nanomedicine, a branch of modern clinical medicine, which combines high selectivity in targeting tumor cells and low toxicity. Thanks to these peculiar characteristics, gold nanoparticles appear as the starting point for the development of new gold-based therapeutic strategies in oncology. Here, the new gold-based therapeutic agents developed in recent years are described, with particular emphasis on the possible applications in clinical practice as anticancer agents, with the aim that their application will give rise to a new golden age in oncology and a breakthrough in the fight against cancer.

Cost of Cancer Care: Issues and Implications

2007 ◽  
Vol 25 (2) ◽  
pp. 180-186 ◽  
Author(s):  
Neal J. Meropol ◽  
Kevin A. Schulman
Keyword(s):  
Health Care ◽  
Health Policy ◽  
Clinical Practice ◽  
Cancer Care ◽  
Medical Technology ◽  
Clinical Medicine ◽  
Scientific Progress ◽  
Medical Spending ◽  
Cost Of Health Care

Medical technology is increasingly costly in most fields of clinical medicine. Oncology has not been spared from issues related to cost, in part resulting from the tremendous scientific progress that has lead to new tools for diagnosis, treatment, and follow-up of our patients. The increasing cost of health care in general (and cancer care in particular) raises complex questions related to its effects on our economy and the citizens of our society. This article reviews the macroeconomic principles and individual behaviors that govern medical spending, and examines how cost disproportionately affects various populations. Our overall goal is to frame debate about health policy concerns that influence the clinical practice of oncology.

scholarly journals Quercetin: Its Main Pharmacological Activity and Potential Application in Clinical Medicine

2020 ◽  
Vol 2020 ◽  
pp. 1-13
Author(s):  
Dengyu Yang ◽  
Tiancheng Wang ◽  
Miao Long ◽  
Peng Li
Keyword(s):  
Clinical Practice ◽  
Pharmacological Activity ◽  
Broad Spectrum ◽  
Potential Application ◽  
Clinical Medicine ◽  
Biological Activities ◽  
Medical Application ◽  
Scientific Basis ◽  
Flavonoid Compound ◽  
Antioxidant Mechanism

Quercetin is a flavonoid compound widely present in plants and exhibits a variety of biological activities. Research on quercetin has shown its potential for medical application. In this research, we elucidate its antioxidant mechanism and the broad-spectrum antibacterial and antiparasite properties; summarise its potential application in antioncology and cardiovascular protection and anti-immunosuppression treatment; and demonstrate its ability to alleviate the toxicity of mycotoxins. This research is expected to offer some insights and inspirations for the further study of quercetin, its properties, and the scientific basis for its better application in clinical practice.

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