Psycho-emotional characteristics of persons addicted to synthetic drugs, depending on the timing of drugs cessation

2021 ◽  
Vol LIII (2) ◽  
pp. 34-41
Author(s):  
Olga N. Patrikeeva ◽  
Irina G. Solovieva ◽  
Regina A. Retser ◽  
Andrey V. Larin ◽  
Sofiya E. Vinokurova ◽  
...  

The research aim was to study the characteristics of psychoemotional response in persons with dependence on synthetic drugs (synthetic cathinones and synthetic cannabinoids) at different stages of abstinence from consumption of psychoactive substances. Methods. Clinical and pathopsychological examination of 127 patients with dependence on synthetic drugs was carried out. All patients are male. Of these, 83 people with a period of abstinence from 3 to 6 months and 44 people with a period of abstinence from 6 to 18 months. The control group consisted of 55 healthy men. We used a clinical interview, the Hospital Anxiety and Depression Scale, the A. Bass and A. Darki questionnaire for diagnosing the parameters of aggression, the STAXI questionnaire of the property-state and expression of anger, the Toronto Alexithymia Scale, the Life Style Index of KellermanPlutchek. Results. It was found that patients with dependence on synthetic drugs have a significantly higher level of anxiety, aggression, more pronounced manifestations of alexithymia in comparison with healthy patients, regardless of the duration of remission. It was revealed that in persons with abstinence from drug use for more than six months, on the one hand, the ability to control the manifestation of anger increases significantly, on the other hand, depressive manifestations intensify and suicidal risk increases in comparison with addicts with a shorter period of abstinence. Conclusion. Emotional disturbances in addicted to synthetic drugs (cathinones and cannabinoids) are persistent and persist even during periods of prolonged abstinence.

2010 ◽  
Vol 18 (3) ◽  
pp. 331-338 ◽  
Author(s):  
Francisca Elisângela Teixeira Lima ◽  
Thelma Leite de Araújo ◽  
Edilma Casimiro Gomes Serafim ◽  
Ires Lopes Custódio

The objective was to evaluate the influence of the Nursing Consultation Protocol in aspects of anxiety and depression in patients after myocardial revascularization using the Hospital Anxiety and Depression scale (HAD). A randomized clinical trial developed in the outpatient clinic of a public hospital in Fortaleza-Ceará. One hundred and forty six patients, who underwent myocardial revascularization, composed the population, providing the sample of 39 patients in the control group (CG) and 39 in the intervention group (IG). The results were presented in tables. Anxiety had a mean of 5.41 in the CG and a median of 5 and a mean in the IG of 5.21 and a median of 4. Depression predominated in the CG, with a mean 4.82 and a median of 4, while the IG had a mean of 3.79 and a median of 3. It was found that people monitored in accordance with the Nursing Consultation Protocol had a lower percentage of anxiety and depression after six months.


2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
M. Brasser

Background:The safety and efficacy of pregabalin in Generalized Anxiety Disorder (GAD) has been confirmed based on the results of 7 large, placebo-controlled trials. We report data on different patient populations from an open-label non-interventional observational trial under naturalistic conditions.Methods:331 physicians (mainly psychiatrists) recruited 578 adult GAD patients and documented treatment with pregabalin over 4 weeks. GAD severity was rated by the patients using Hospital Anxiety and Depression Scale (HADS) and a 100mm daily Visual Analogue Scale (VAS-anxiety). Spontaneous Adverse Events (AEs) were collected.Results:Most patients received an initial dose of 150mg pregabalin per day, which was then increased to 300mg per day. Mean HADS-A Baseline Score (15.5 vs. 14.6) and Improvement (-5.9 vs. -6.1) was similar in younger (≤65 years, n=484) and older (>65 years, n=71) patients. Treatment naive patients had a lower HADS-A-Score (mean 14.2) than patients who got pregabalin add-on to their current medication (mean 15.8); both groups showed a similar improvement by 5.9 points over 4 weeks. A total of 26 AEs occured during this study, most of them rated mild to moderate in severity with no treatment related serious events. The pattern of events resembled the one known from clinical trials and post-marketing experience. 1.2% of subjects discontinued treatment due to adverse events.Conclusion:Data from this non-interventional study in GAD show that pregabalin demonstrates similar effectiveness in adults and older (≤65 years) patients, regardless of whether used as mono- or adjunctive therapy.


2015 ◽  
Vol 24 (5) ◽  
pp. 446-449 ◽  
Author(s):  
Charlsea Prichard ◽  
Patricia Newcomb

BackgroundIn intensive care environments, patients’ families are often encouraged to participate in their loved one’s care; however, many family members feel anxious, depressed, and unsure about how to help patients.ObjectivesTo determine (1) the feasibility of teaching family members a simple intervention combining hand massage with essential oils in a trauma intensive care unit and (2) an effect size for use in designing a more powerful trial.MethodA quasi-experimental pilot study of the effect of a family-delivered touch treatment on anxiety and depression of family members of patients. Fifteen family members were assigned to a treatment group, and 15 family members were assigned to a control group. The treatment consisted of the application of hand massage with essential oils for 6 sessions. Each session lasted 5 minutes and was presented twice a day for 3 days.ResultsThe 5-minute intervention was associated with positive change in anxiety and depression scores on the Hospital Anxiety and Depression Scale (HADS) among family members visiting patients. The magnitude of change (improvement) in anxiety scores within the group of treated family members was significantly greater than within family members in the control group.ConclusionAdministering a brief hand massage using pleasant-smelling oils to patients in an intensive care unit may reduce anxiety of family members who administer the treatment.


2018 ◽  
Vol 41 (9) ◽  
pp. 1254-1269
Author(s):  
Chunyan Nie ◽  
Tianzhu Li ◽  
Xiaoxia Guo

The objective of this article is to investigate the effects of intensive patients’ education and lifestyle improving program (IPEL) on anxiety, depression, and overall survival (OS) in coronary artery disease (CAD) patients with anxiety and depression. In all, 224 CAD patients with anxiety and depression were randomly assigned to IPEL or control group. In Stage I, the IPEL group received IPEL and usual care, while the control group only received usual care. In Stage II, patients were further followed up and OS analysis was performed. Hospital Anxiety and Depression Scale–anxiety (HADS-A) and HADS–depression (HADS-D) were used to assess anxiety and depression. IPEL reduced HADS-A score at Month 9 (M9)/M12, and the percentage of anxiety at M12 and HADS-A score changed. IPEL reduced HADS-D score at M12, and the percentage of depression at M12 and HADS-D score changed compared with control. Patients with nonanxiety/nondepression at M12 in the IPEL group showed better OS. IPEL reduces anxiety and depression and improves OS in CAD patients.


2020 ◽  
Vol 17 ◽  
pp. 147997312093329
Author(s):  
Stephanie C Wynne ◽  
Suhani Patel ◽  
Ruth E Barker ◽  
Sarah E Jones ◽  
Jessica A Walsh ◽  
...  

The aims of the study were to evaluate the responsiveness of Hospital Anxiety and Depression Scale-Anxiety (HADS-A) subscale and HADS-Depression (HADS-D) subscale to pulmonary rehabilitation (PR) in patients with bronchiectasis compared to a matched group of patients with chronic obstructive pulmonary disease (COPD) and provide estimates of the minimal clinically important difference (MCID) of HADS-A and HADS-D in bronchiectasis. Patients with bronchiectasis and at least mild anxiety or depression (HADS-A ≥ 8 or/and HADS-D ≥ 8), as well as a propensity score-matched control group of patients with COPD, underwent an 8-week outpatient PR programme (two supervised sessions per week). Within- and between-group changes were calculated in response to PR. Anchor- and distribution-based methods were used to estimate the MCID. HADS-A and HADS-D improved in response to PR in both patients with bronchiectasis and those with COPD (median (25th, 75th centile)/mean (95% confidence interval) change: HADS-A change: bronchiectasis −2 (−5, 0), COPD −2 (−4, 0); p = 0.43 and HADS-D change: bronchiectasis −2 (−2 to −1), COPD −2 (−3 to −2); p = 0.16). Using 26 estimates, the MCID for HADS-A and HADS-D was −2 points. HADS-A and HADS-D are responsive to PR in patients with bronchiectasis and symptoms of mood disorder, with an MCID estimate of −2 points.


Author(s):  
Benjamín Romero-Gómez ◽  
Paula Guerrero-Alonso ◽  
Juan Manuel Carmona-Torres ◽  
Blanca Notario-Pacheco ◽  
Ana Isabel Cobo-Cuenca

Background: Hypothyroidism has several symptoms (weight gain, arrhythmias, mood changes, etc.). The aims of this study were (1) to assess the prevalence of anxiety and depression in levothyroxine-treated hypothyroid women and in women without hypothyroidism; (2) to identify variables associated with anxiety and depression. Methods: A case-control study was performed with 393 women. Case-group: 153 levothyroxine-treated hypothyroid women. Control-group: 240 women without hypothyroidism. Convenience sampling. Instrument: The Hamilton Hospital Anxiety and Depression Scale (HADS), and a sociodemographic questionnaire. Results: The prevalence of anxiety in levothyroxine-treated hypothyroid women was higher than in women without hypothyroidism (29.4% vs. 16.7%, χ2 p < 0.001). The prevalence of depression in the case group was higher than in the control group (13.1% vs. 4.6%, χ2 p < 0.001). Levothyroxine-treated hypothyroid women were more likely to have anxiety (OR = 2.08, CI: 1.28–3.38) and depression (OR = 3.13, IC = 1.45–6.45). Conclusion: In spite of receiving treatment with levothyroxine, women with hypothyroidism are more likely to have depression and anxiety. Health professionals need to assess the mood of women with hypothyroidism. Although levothyroxine is a good treatment for the symptoms of hypothyroidism, it may not be enough to prevent development or persistence of depression and anxiety by itself.


2020 ◽  
pp. 16-20
Author(s):  
Ірина Володимирівна Малишева

Introduction. The article considers the features of the psycho-emotional state of pregnant women with drug addiction.Aim. To study the features of the psycho-emotional state of pregnant women with drug addiction using the Hospital Anxiety and Depression Scale HADS and SWLS Life Satisfaction Scales.Materials and methods. The study included 156 pregnant women, including 96 women with drug addiction (main group). The control group included 60 pregnant women.Results. A higher frequency of subclinically expressed anxiety and depression in pregnant women with drug addiction 62.5% (60 women) compared with women of the control group 8.3% (5 women). Life satisfaction in women the main group was at a low level, namely almost dissatisfied with life 40.6% (39 women) or dissatisfied with life 50% (48 women).Conclusions. The study showed the presence of psycho-emotional changes areas in the form of increased anxiety and depression, as well as decreased levels life satisfaction in pregnant women with drug addiction.


Cephalalgia ◽  
2003 ◽  
Vol 23 (6) ◽  
pp. 451-455 ◽  
Author(s):  
C Wacogne ◽  
JP Lacoste ◽  
E Guillibert ◽  
FC Hugues ◽  
C Le Jeunne

This study investigated the intensity of stress, anxiety and depression in a sample of 141 migraineurs compared with a control group of 109 non-migraine workers matched for age and sex. Stress was measured using the Perceived Stress Questionnaire, and anxiety and depression using the Hospital Anxiety and Depression Scale. Results indicated that stress and anxiety were higher in the migraine group than in the control group and above the clinical level. Depression scores remained low in both groups, under clinical relevance. Stress is a primordial factor in the triggering and perpetuation of migraine attacks. The high score of the items ‘morning fatigue’, ‘intrusive thoughts about work’, ‘feeling under pressure’, ‘impatience’, and ‘irritability’ of the stress questionnaire in the migraineurs is particularly significant in the intensive stress response. It seems necessary to manage stress to improve the daily life of migraineurs and to study the link between stress, anxiety and migraine.


Author(s):  
Shireen Jawed ◽  
Benash Altaf ◽  
Rana Muhammad Tahir Salam ◽  
Farhat Ijaz

Abstract Objectives: This study was aimed to determine and compare the frequency of the emotional disturbances, anxiety and depression among the medical students on Hospital Anxiety Depression scale (HAD) score among the hostelites and day scholars. Methodology: This cross sectional study was conducted at private medical college in Faisalabad, Pakistan, from March 2019 to April 2019, comprising of 105 male and female students. Validated Hospital Anxiety depression scale (HAD-A and HAD-D) was used to collect data from 1st year and 2nd year MBBS students in order to evaluate anxiety and depression among them.  Data was analyzed on SPSS 21. Pearson’s Chi-square was applied to compare the percentages of anxious and depressed subjects among the studied group. Independent sample t-test was applied for comparison of mean HAD scores between hostelites and day scholars. P value ? 0.05 was taken as significant. Results: There were 105 students in the study with a mean age of 19.4± 0.68 years. Overall, 82.7% students had anxiety, and 52.1% suffered from depression. Average HAD –A and HAD- D scores were 11.2 ± 3.41 and 7.2 ± 3.37 respectively. Greater number of hostelites was suffering from emotional disturbances as compared to day scholars.  HAD –A scores was significantly higher in hostelites than day scholars with P value 0.003*(11.85 ± 3.42 Vs 10.92 ±2.56).  HAD- D scores were also higher in hostilities but difference was insignificant. (7.57± 3.42   Vs 6.85 ±1.58) Continuous...


2017 ◽  
Vol 7 (2) ◽  
pp. 146-149 ◽  
Author(s):  
Orhan Sezgin ◽  
Serkan Yaras ◽  
Fehmi Ates ◽  
Engin Altintas ◽  
Bunyamin Saritas

ABSTRACT Aim Percutaneous needle liver biopsy (PLB) is frequently associated with pain and anxiety. This may discourage the patients for biopsy, and rebiopsies, if needed. We planned a study to investigate the efficacy of additional analgesia or sedation for PLB. Materials and methods The study has been designed as a single-center, prospective study. The PLB was planned for 18- to 65-year-old consecutive patients who were included in the study. The patients were divided into three premedication groups as control, Meperidine, and Midazolam. Hospital Anxiety and Depression Scale (HADS) was used to measure each subject's anxiety level. Fifteen minutes before the biopsy, 1 mL 0.9% NaCl subcutaneously (sc), 1 mg/kg (max 100 mg) Meperidine sc, or 0.1 mg/kg (max 5 mg) Midazolam intravenously was administered to patients respectively. Then PLB was done with 16 G Menghini needle. The day after, the patients were asked about feelings regarding biopsy. Results Groups were similar by gender and age. The HADS scores prior to PLB and on visual analog scale (VAS, 1—10 points) score during PLB were similar. In the three groups, 7, 12, and 7 patients, respectively, experienced no pain. Other patients explained pain as mild or moderate or severe. The number of patients who agreed for possible rebiopsy was higher in Meperidine and Midazolam groups than in the control group. Conclusion Premedication with Meperidine or Midazolam in PLB would improve patients' tolerance, comfort, and attitude against a possible repeat PLB. How to cite this article Sezgin O, Yaras S, Ates F, Altintas E, Saritas B. Effectiveness of Sedoanalgesia in Percutaneous Liver Biopsy Premedication. Euroasian J Hepato-Gastroenterol 2017;7(2):146-149.


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