THE NATURE OF REPRODUCTIVE DISORDERS IN WOMEN WITH HYPERANDROGENISM SYNDROMEq

2021 ◽  
Vol 2 (4) ◽  
pp. 13-16
Author(s):  
M. M Asatova ◽  
◽  
S. M. Safoeva
Keyword(s):  
Laboratory Data ◽  
Clinical Manifestations ◽  
Reproductive Age ◽  
Reproductive Disorders ◽  
Menstrual Disorders ◽  
Women Of Reproductive Age ◽  
Perinatal Center ◽  
Androgen Secretion ◽  
The City ◽  
Anovulatory Infertility

PCOS occupies a leading place in the population of women with clinical manifestations of excessive androgen secretion and is detected in 72.1-82% of cases, while among women with anovulatory infertility-in 55-91% of cases (Lizneva D. (2016). The criteria, prevalence and phenotypes of PCOS. Fertil.Steril., 106 (1), 6-15). The article discusses the results of a study conducted based on the City Perinatal Center of Tashkent to study the frequency and nature of reproductive disorders in women with symptoms of hyperandrogenism. The study involved women of reproductive age with various menstrual disorders and infertility. The analysis of anamnestic, subjective and objective, clinical and laboratory data of patients was carried out

scholarly journals HIV and infertility: neuro-endocrine and metabolic aspects

2021 ◽  
Vol 12 (4) ◽  
pp. 73-80
Author(s):  
O. Ya. Leshchenko ◽  
E. V. Genich ◽  
M. A. Darenskaya ◽  
L. I. Kolesnikova
Keyword(s):  
Lipid Peroxidation ◽  
Antioxidant Status ◽  
Reproductive Age ◽  
Neuroendocrine Regulation ◽  
Reproductive Disorders ◽  
Sociological Study ◽  
Women Of Reproductive Age ◽  
Cross Sectional ◽  
Prognostic Assessment ◽  
Hormonal Levels

Objective: to establish a correlation of the main neuroendocrine and metabolic parameters associated with infertility and to provide a prognostic assessment of reproductive disorders in HIV-infected women, stages 4.Materials and methods. Cross-sectional, cohort, clinical and sociological study of fertility of 83 women of reproductive age with HIV, stages 4.Results. The most significant indicators of lipid peroxidation and neuroendocrine regulation systems have been established in patients with HIV infection and reproductive disorders, which will make it possible to predict these disorders in the future. Decreased ovarian reserve, ovarian steroid function, increased pituitary prolactinergic function are associated with a deficiency of a number of antioxidants (retinol, tocopherol, superoxide dismutase) and the development of oxidative stress with a predominant accumulation of intermediate lipid peroxidation products in HIV-infected women with infertility.Conclusion. The pathogenetically substantiated principle of the correction of antioxidant status is the use of a-tocopherol and retinol preparations and the correction of hormonal levels in HIV-infected women with reproductive disorders.

Facets of the problem of infiltrative endometriosis: from pathogenesis to effective therapy

GYNECOLOGY ◽  
2021 ◽  
Vol 23 (2) ◽  
pp. 117-124
Author(s):  
Viktor E. Radzinskii ◽  
Mekan R. Orazov ◽  
Ljudmila M. Mihaleva ◽  
Madina A. Bekulova
Keyword(s):  
Pelvic Pain ◽  
Economic Burden ◽  
Clinical Manifestations ◽  
Effective Therapy ◽  
Reproductive Age ◽  
Personal Life ◽  
Depression And Anxiety ◽  
Women Of Reproductive Age ◽  
Unresolved Problem ◽  
High Prevalence

Endometriosis remains an unresolved problem in gynecology. The urgency of the fight against this disease is due to its high prevalence among women of reproductive age. Endometriosis, especially its infiltration forms, affects all aspects of the patients life, its clinical manifestations pelvic pain, dyspareunia, dysmenorrhea, dyschezia, lead to social disadaptation, problems in personal life, depression and anxiety. The socio-economic burden of the disease motivates researchers to further study the pathogenesis of endometriosis and search for pathogenetically justified pharmacological solutions.

Clinical manifestations of neurosyphilis in women of reproductive age

2016 ◽  
Vol 7 (2) ◽  
pp. 57-62
Author(s):  
Maria L Chuhlovina ◽  
Denis V Zaslavsky ◽  
Ekaterina A Bichun
Keyword(s):  
Rating Scale ◽  
Congenital Syphilis ◽  
Clinical Manifestations ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Clinical Dementia Rating ◽  
Clock Drawing Test ◽  
Mattis Dementia Rating Scale ◽  
Moderate Dementia ◽  
Dementia Rating Scale

The research objective is investigation of clinical manifestations of neurosyphilis in women of reproductive age. The diagnoses were based on complaints, anamnestic information, neurological examinations, dermatovenerology consultations, serological blood and liquor tests. All the patients underwent psychometric tests. The following methods were used: mini-mental state examination (MMSE), “Frontal Assessment Battery”, Clinical Dementia Rating scale, Clock drawing test, “Information-Memory-Consideration Concentration” test, Mattis Dementia Rating Scale. Nine patients with early neurosyphilis (between the ages of 18 to 40) and eight patients with late neurosyphilis (between the ages of 28 to 43) were surveyed. Syphilitic meningitis (six cases), meningovascular neurosyphilis (three cases) were found in patients with early neurosyphilis. As for the patients with late neurosyphilis, two of them were diagnosed to have syphilitic meningitis, two patients had meningovascular neurosyphilis, two had progressive paralysis, tabes dorsalis was identified in one patient, one had taboparalysis. Only three patients showed specific skin and mucic manifestations. The patients at all the stages of neurosyphilis demonstrated mild cognitive impairments. Moderate dementia was found in one patient with early meningovascular neurosyphilis and one patient with progressive paralysis. This article considers a clinical case of a female patient with early syphilitic meningitis who had a baby with congenital syphilis.

scholarly journals Medical and social aspects of reproductive behavior and health of residents of Moscow region

2016 ◽  
Vol 24 (4) ◽  
pp. 25-31
Author(s):  
O E Konovalov ◽  
A K Haritonov ◽  
E E Zhiltsova
Keyword(s):  
Ordinal Number ◽  
Reproductive Age ◽  
Social Aspects ◽  
Women Of Reproductive Age ◽  
Important Condition ◽  
Number Of Children ◽  
The Family ◽  
Perinatal Center ◽  
Happy Family ◽  
Artificial Abortion

The results of the survey 596 women of reproductive age living in the service area of the Moscow Regional Perinatal Center are analyzed in the article. Among the women surveyed 91,2% had a positive attitude toward childbearing and they considered an important condition to create a happy family the presence of children. At that 58,4% of them would like to have in their family of two children and 25,7% - three or more. Only every second woman believes that she has a desired number of children in the family. Has been established that pregnancies in 10,3% cases ended artificial abortion and in 1,9% spontaneous abortion. Reliable differences have been revealed in the frequency of pregnancies depending on the level of education. It was established that with increasing ordinal number of pregnancy reliably reduced the proportion of births a living child. Each tenth of the women surveyed has reported about complications after abortion. 8,9% of respondents have been treated for infertility, 13,0% from the miscarriage. 56,4% of women used protection from pregnancy. With this purpose most often a condom was used and interrupted intercourse.

scholarly journals A Community Based Study on Menstrual Disorders Among the Rural Women of Reproductive Age

2017 ◽  
Vol 5 (4) ◽  
pp. 270-276 ◽  
Author(s):  
Durai Vanitha ◽  
Shanthi Edward ◽  
Suresh Varadharajan ◽  
Muthuthandavan Anita Rani
Keyword(s):  
Rural Women ◽  
Reproductive Age ◽  
Menstrual Disorders ◽  
Women Of Reproductive Age ◽  
Community Based

scholarly journals LEPTIN LEVEL IN WOMEN OF REPRODUCTIVE AGE WITH THE SYNDROME OF THE POLYCYSTIC OVARY IN COMPARISON WITH HEALTHY WOMEN

2019 ◽  
Vol 6 (1) ◽  
pp. 32-37
Author(s):  
Anzhelika Yu. Beglova ◽  
S. I Elgina
Keyword(s):  
Metabolic Syndrome ◽  
Polycystic Ovary ◽  
Overweight And Obesity ◽  
Reproductive Age ◽  
Menstrual Disorders ◽  
Women Of Reproductive Age ◽  
Healthy Women ◽  
Diagnostic Criterion ◽  
The Relationship ◽  
Ultrasound Parameters

Material and methods. The study included 200 women of reproductive age, of whom the 1st group included 100 PCOS female patients and the 2nd group included 100 healthy women examined using clinical, instrumental, laboratory, and statistical methods. Results. Metabolic syndrome was diagnosed in 38 (38.0%) PCOS women of early reproductive age, while in healthy women only in 25 (25.0%) (p = 0.102). The serum leptin content in PCOS women amounted of 13.85 ng/ml (4.15-17.6), which was not significantly different from that of healthy women - of 8.9 ng/ml (5.5-18.4) (p = 0.732). However, in women with manifestations of metabolic syndrome (overweight and obesity), the level of leptin was higher than in women without metabolic syndrome - 16.7 ng/ml (15.6-18.8) and 19.3 ng/ml (17.4-22.8) in PCOS women - 31.7 ng/ml (21.6-38.6) and 27.3 ng/ml (20.1-32.1) in healthy women (p = 0.045 and 0.604, respectively). An increase in its level correlated with an increase in BMI (p = 0.001). We found that an increase in leptin levels in PCOS women of reproductive age correlated with its main manifestations: menstrual disorders, infertility and ultrasound parameters of the ovaries, with an increase in BMI, the relationship was stronger. Conclusion. Thus, in PCOS women of reproductive age, metabolic syndrome is more often diagnosed than in healthy women. Overweight and obesity are of major importance in the formation of metabolic disorders. Increased leptin levels exacerbate metabolic manifestations, leading to impaired ovulation and fertility. The results show the need to determine the level of leptin as an additional diagnostic criterion for metabolic syndrome in PCOS cases.

scholarly journals Consumption Of Transfer Factor Belle Vie On The WUS With Menstrual Disorders In The City Of Makassar

2018 ◽  
pp. 318-327
Author(s):  
Kesna Nathasya Novitasari ◽  
Andi Nurlinda ◽  
Reza Aril Ahri
Keyword(s):  
Transfer Factor ◽  
Pap Smear ◽  
Descriptive Analysis ◽  
Reproductive Organs ◽  
Reproductive Age ◽  
Depth Information ◽  
Menstrual Disorders ◽  
Depth Interview ◽  
Medical Facilities ◽  
The City

Reproductive age women having lots of menstrual problems or abnormal menstruation, such as menstrual syndrome and irregular menstruation. This research aims to review and analyze in-depth information regarding the effectiveness of the consumption of the Transfer Factor Belle Vie Against menstrual disorders in women age early. The method of this research is qualitative research using the descriptive analysis. Engineering data collection using the dwarf in-depth interview (in-depth interviews) as well as the documentation continuously as long as the research progresses. The results of this study indicate that menstrual disorders experienced by the informant. That is the pain at the time of menstruation, menstrual blood is too many and manifest irregularities of menses. Knowledge of the informant about menstrual disorders if you have menstrual irregularities each month and menstruation is prolonged and the factors that affect the onset of menstrual disorders are factors of nutrient intake, stress, work, physical activity, and obesity. Way or attempt the informant in tackling menstrual disorders there are soon check into medical facilities, given hormone therapy, conducted a pap smear. The dangers that can be caused by menstrual disorders could hit polyps, myomas, cancer, and tumors. Daily habits such as diet, exercise habits, the activity can also affect the menstrual disorders. TF Bellevie according to informants quite effective in dealing with menstrual disorders, with the regularity of consuming and appropriate recommended dose. Consume TF Bellevie continuously also does not cause any side effects and harm against women's reproductive organs. Menstrual disorders experienced by women of fertile age should advance in advance by a doctor so it can determine the proper care for reproductive health although TF Bellevie quite effective in tackling the problem.

scholarly journals Clinicopathologic Aspects of Endometrial Proliferous Processes in Women of Reproductive Age

2018 ◽  
Vol 24 (4) ◽  
Author(s):  
Iryna Vovk ◽  
Nataliya Gorban ◽  
Valentyna Kondratiuk
Keyword(s):  
Uterine Leiomyoma ◽  
Endometrial Hyperplasia ◽  
Statistical Data ◽  
Reproductive Age ◽  
Menstrual Disorders ◽  
Women Of Reproductive Age ◽  
Endometrial Polyps ◽  
Morphological Research ◽  
Endometrial Pathology

The peculiarities of benign proliferative pathology of endometrium including their combination in women of reproductive age are reviewed in the article.Materials and methods. The results of pathohistological research of benign proliferative pathology of endometrium (without atypia) were analyzed. Statistical data processing was performed by means of MedStat software package.Results. The obtained results revealed that benign proliferative pathology of endometrium is one of the most frequent gynaecological malignancies among female patients of reproductive age accounting for 52.2 % cases. Endometrial polyps were found to be accompanied by morphological peculiarities indicating chronic inflammatory process in endometrium in 56.5% cases (р<0.05) in comparison with endometrial hyperplasia in 38.2% cases, proving the presence of long-term inflammation in endometrial tissue and its trigger role in the development of the proliferative processes. Among patients with chronic salpingo-oophoritis, infertility was revealed in almost half of cases (44.5% of patients with endometrial polyps, 40.5% of patients with endometrial hyperplasia and 48.3% of women with combined proliferative pathology of endometrium) clinically confirming the data of morphological research. Peculiar signs of proliferative processes in genitals were determined, namely coexistence of uterine and endometrial pathology: endometrial hyperplasia was found in 40.4% of patients with uterine leiomyoma and 30.3% of patients with adenomyosis. The same combinations were peculiar for patients with endometrial polyps: endometrial hyperplasia was found in 30.1% of patients with uterine leiomyoma and 36.3% of patients with adenomyosis. Menstrual disorders were revealed in every third woman with endometrial hyperplasia (30.3%) and co-existent polyposis (30.2%).

Substitution therapy with levothyroxine in balancing of hormonal interactions at subclinical hypothyroidism in reproductive-age women

2018 ◽  
pp. 46-48
Author(s):  
B.M. Ventskovskii ◽  
◽  
L.M. Varchenko ◽  
Keyword(s):  
Reproductive System ◽  
Subclinical Hypothyroidism ◽  
Clinical Manifestations ◽  
Reproductive Age ◽  
Menstrual Disorders ◽  
Substitution Therapy ◽  
Hormonal Profile ◽  
Reproductive Age Women ◽  
Selective Dopamine ◽  
Hormonal Interactions

6 months levothyroxine appointment in 80 reproductive-age women with subtypical hypothyroidism contributed to the normalization of hormonal interactions in the pituitary-ovarian axis with the elimination of reproductive system disorders in 58.8% cases. Hormonal disorders with hyperprolactinemia persisted in 41.2% of women, so they continued substitution therapy with the inclusion of selective dopamine receptor blocker of cabergoline. After 9, and even more after 12 months of this treatment, both the normalization of the hormonal profile and the elimination of clinical manifestations of disorders in the reproductive system were achieved. Key words: hyperprolactinemia, cabergoline, menstrual disorders, reproductive system, hormones.

Clinical experience of non-hormonal correction of the luteal phase deficiency in women of reproductive age

2019 ◽  
pp. 24-26
Author(s):  
T.R. Streltsova ◽  
◽  
N.R. Simonov ◽  
Keyword(s):  
Menstrual Cycle ◽  
Blood Loss ◽  
Luteal Phase ◽  
Main Group ◽  
Reproductive Age ◽  
Control Group ◽  
Second Phase ◽  
Menstrual Disorders ◽  
Women Of Reproductive Age ◽  
Cycle Disorders

The objective: to study the clinical efficacy of two schemes of using the monocomponent herbal preparation Cyclodynon® in women of reproductive age with complaints of various menstrual cycle disorders diagnosed with latent hyperprolactinemia and second phase failure of the menstrual cycle based on the results of clinical and hormonal studies. Materials and methods. The study included 60 patients aged 25–38 years suffering from PMS. The main group (n = 30) received Cyclodynon® in an ascending pattern: from 1 to the 14th day of the menstrual cycle – 40 drops 1 time a day and from the 15th day to the end of the cycle – 40 drops 2 times a day. The control group (n = 30) – 40 drops 1 time per day until the end of the cycle for three menstrual cycles. Results. After 3 months in the main group there was a more significant decrease in the level of prolactin (from 28.3 to 18.4 ng / ml) as compared with the control (from 27.8 to 23.1 ng / ml). Increased progesterone and estradiol production was also more significantly observed in the main group. The dynamics of normalization of the duration of the menstrual cycle and the volume of blood loss was also more significant in the main group and amounted to 93.3%. Conclusion. The use of an increasing treatment regimen with Cyclodynon® in women with a luteal phase deficiency on the background of hyperprolactinemia has advantages over the use of a standard continuous regimen with respect to a more rapid normalization of hormonal homeostasis, the duration of the menstrual cycle and blood loss. Key words: luteal phase deficiency, hyperprolactinemia, menstrual disorders, Cyclodynon®.

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