scholarly journals A clinical study on role of caroverine in the management of tinnitus

2016 ◽  
Vol 6 (1) ◽  
pp. 176
Author(s):  
Abha Kumari ◽  
Sandeep Kumar
Keyword(s):  
Complete Relief ◽  
Sound Stimulation ◽  
Frequency Matching ◽  
Group I ◽  
Significant Difference ◽  
Before And After ◽  
Group 2 ◽  
Sensory Neural ◽  
Group 1

Background: Tinnitus is a perception of sound in the absence of sound stimulation and it continues to be a significant and costly health problem without a uniformly accepted treatment. The signals between the inner hair cells and the cochlear nerve fibres are most likely to be transmitted by glutamate. Hence, present study was undertaken to assess the role of caroverine which is a glutamate receptor antagonist in the management of sensory neural tinnitus.Methods: The present study was conducted among 50 adult patient with sensory neural tinnitus divided into two groups with 25 patients in each group. In group 1 caroverine 20 mg twice daily for a period of 90 days was administered and in group 2 placebos was given. The effect of caroverine and placebo on subjective relief and objective improvement was evaluated by using THI (Tinnitus Handicap, Inventory) scoring, Tinnitus frequency matching before and after the administration of caroverine and placebo.Results: In Group I reduction in tinnitus was seen in 16 patients (64%) in 90 days. In group II (placebo group) improvement was seen in 20% of the patient. Significant difference with respect to treatment was noted. In group 1, 8% of the patient showed complete relief from the tinnitus. 44% of the patient showed improvement below 50% whereas 12% of the patient showed improvement more than 50%.Conclusions: Carvoverine had shown a statistically significant improvement in tinnitus management. 

Attitude of the Canine in Secondary Bone-Grafted and Nongrafted Patients with Cleft Lip and Palate

2005 ◽  
Vol 42 (6) ◽  
pp. 679-686 ◽  
Author(s):  
Enkhtuvshin Gereltzul ◽  
Yoshiyuki Baba ◽  
Kimie Ohyama
Keyword(s):  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Panoramic Radiography ◽  
Control Groups ◽  
Significant Difference ◽  
Before And After ◽  
Group 2 ◽  
Two Stages ◽  
And Control ◽  
Group 1

Objective To investigate the eruption pattern of the cleft-side canine regarding its pre-eruption position relative to the cleft in bone-grafted (BG) and nongrafted (NonBG) patients with cleft lip and palate. Methods Fifty-three patients with cleft lip and palate (21 BG, 32 NonBG) were examined by panoramic radiography and posteroanterior cephalography taken before and after canine eruption. Subjects were categorized into BG, NonBG, and control groups. Canines at the pre-eruption stage were categorized as close to (group 1) or distant from (group 2) the cleft area. The canine angle and its change between the two stages were evaluated. Results No significant differences were noted between the initial canine angle of the BG and NonBG groups. Although canines in the BG group erupted without a significant change in angle, the canine angle increased significantly (p < .0001) in the NonBG and control groups. In group 1, a greater change in canine angle was noted in the NonBG (p < .05) and control (p < .01) groups than in the BG group. In group 2, no significant difference was noted among the three groups. Conclusions In BG patients, a canine located near the cleft appears to erupt at the same angle as it had before grafting. However, in NonBG patients, it erupts more vertically, guided by cortical bone. For canines distant from the cleft area, there is no significant difference in the change in angulation between NonBG and BG patients.

scholarly journals Orthosiphon versus Placebo in Nephrolithiasis with Multiple Chronic Complaints: A Randomized Control Trial

2009 ◽  
Vol 6 (4) ◽  
pp. 495-501 ◽  
Author(s):  
Amorn Premgamone ◽  
Pote Sriboonlue ◽  
Srinoi Maskasem ◽  
Wattana Ditsataporncharoen ◽  
Bungornsri Jindawong
Keyword(s):  
Myofascial Pain ◽  
White Blood Cells ◽  
Analog Scale ◽  
Significant Difference ◽  
Before And After ◽  
The Mean ◽  
Randomized Control ◽  
Group 2 ◽  
Primary Measure ◽  
Group 1

Nephrolithiasis in the communities of Northeast Thailand frequently presents with multiple chronic health complaints, i.e. myofascial pain, back pain, dyspepsia, arthralgia, headache, fatigue, frank paresthesia, dysuria and any of these aggravated by purine-rich food (PRF). We assessed the efficacy of Orthosiphon in treating subjects with at least two active symptoms and negative for urine white blood cells. Subjects were randomly allocated to two groups. Crude extract of Orthosiphon given in a capsule (equivalent to 1.6–1.8 g of dried leaves of Orthosiphon) two times a day to Group 1 (n= 36) and a placebo to Group 2 (n= 40) for 14 days. The medication for each subject was packed and its code kept secret until the data analysis. Both groups were asked not to consume any of 25 purine-rich foods (PRFs) during treatment. The primary measure was the reduced sum of active severity symptoms as recorded using the visual analog scale before and after therapy (i.e. on day 7 and 14). The data on 76 subjects were processed. The mean of the total scores (95% CI) of the symptoms in each group were decreased significantly (P< 0.001); 185.6 (153.3, 218.0) to 94.7 (58.2, 131.2) in the Orthosiphon group and 196.1 (164.4, 227.8) to 89.6 (62.8, 116.5) in the placebo group. When comparing between groups, no statistically significant difference was found. The mean consumption in PRFs was significantly decreased (P< 0.001) in both groups; however, Orthosiphon did not have additional benefit over placebo at 7 and 14 days of treatment during which they reduced these foods.

scholarly journals PELATIHAN LONCAT NAIK TURUN TRIBUN DAN PELATIHAN LONCAT NAIK TURUN BANGKU MENINGKATKAN DAYA LEDAK OTOT TUNGKAI PADA PESERTA EKSTRA KURIKULER BOLA VOLI PUTRA SMA NEGERI 1 TEGALLALANG

2019 ◽  
Author(s):  
I Putu Agus Budi Sudarsana ◽  
J. Alex Pangkahila ◽  
Bagus Komang Satriyasa ◽  
Wayan Weta ◽  
I Nengah Sandi ◽  
...  
Keyword(s):  
High School ◽  
T Test ◽  
P Value ◽  
Public High School ◽  
Jump Training ◽  
Explosive Power ◽  
Significant Difference ◽  
Before And After ◽  
Group 2 ◽  
Group 1

ABSTRACTThis study was conducted to determine the increase in limb muscle explosive power. The training was conducted with 5 reps of 3 sets over six weeks in the field of Tegallalang 1 Public High School starting at 17.00 WITA until completion. In this study using 2 groups, namely the 1st group given jump training up and down the stands, the 2nd group was given jump training up and down the bench. The sample for each group is 8 people who have met the requirements of the male volleyball extra-curricular participants of Tegallalang 1 Public High School. Data from leg muscle explosive results obtained from 3 jumps taken before and after training. The results obtained before and after the Group-1 training were 57.5 cm to 70.875 cm and Group-2 were 57.375 cm to 65.75 cm. Hypothesis testing uses an independent t-test at a significance limit of 0.05 (p <0.05). Based on the differences in the results of the intergroup test analysis using independent t-test obtained group-1 and group-2 for p = 0.935 which showed no significant difference before being given treatment with a p value greater than 0.05. Whereas after treatment the group-1 and group-2 were obtained at p = 0.007 which showed a significant difference between groups 1 and 2 groups with a p value smaller than 0.05. It can be concluded that jumping up and down the stands is more effective than jump training up and down the bench in increasing the explosive power of the leg muscles. For this reason, it is expected that sports coaches to apply jumping up and down the stands as an alternative in increasing athletes' explosive power.Keywords: Training jumping up and down the stands, training jumping up and down the bench, explosive muscle power.

scholarly journals Role of CT-guided transthoracic biopsy in the diagnosis of mycobacterial infection

2019 ◽  
Vol 67 (5) ◽  
pp. 850-855
Author(s):  
Kyongmin Sarah Beck ◽  
Dae Hee Han ◽  
Kyo Young Lee ◽  
Seung Joon Kim
Keyword(s):  
Clinical Characteristics ◽  
Mycobacterial Infection ◽  
Diagnostic Process ◽  
Related Factors ◽  
Transthoracic Needle Biopsy ◽  
Ct Guided ◽  
Significant Difference ◽  
Group 2 ◽  
Group 1

Mycobacterial infection(MI) is sometimes diagnosed using CT-guided transthoracic needle biopsy (TNB). However, the exact role of CT-guided TNB in this diagnostic process is not clearly known. The purpose of this study is to analyze the role of CT-guided TNB in patients with MI who present with a focal lung lesion. Of 1233 patients who underwent CT-guided TNB from January 2010 through February 2016 at our institution, patients with a final diagnosis of MI were included for analysis. Clinical characteristics and biopsy-related factors were compared between patients whose diagnosis could be established using TNB samples alone (group 1) and those whose samples from additional tests were necessary for diagnosis (group 2). We also analyzed the possible benefit of CT-guided TNB as compared with bronchoscopy in a subgroup who underwent both procedures. 47 patients with MI were included in the study, with 37 patients (78.7%) in group 1 and 10 patients (21.2%) in group 2. There was no statistically significant difference in clinical characteristics or biopsy-related factors between the two groups. Of 41 patients with MI who underwent both bronchoscopy and TNB, success in diagnosis was solely attributable to TNB in 16 (39.0%) patients; in 19 (46.0%) patients, diagnosis could be made based on bronchoscopy results alone. MI can be successfully diagnosed by CT-guided TNB in about 80% of patients with MI who underwent TNB, but 46% of the patients could have been diagnosed with bronchoscopy results alone. CT-guided TNB is inferior to bronchoscopy in the differentiation of Mycobacterium species even in peripheral lung lesions.

The Role of Hyperbaric Oxygen as Salvage Therapy for Sudden Sensorineural Hearing Loss

2018 ◽  
Vol 127 (10) ◽  
pp. 672-676 ◽  
Author(s):  
Galit Almosnino ◽  
James R. Holm ◽  
Seth R. Schwartz ◽  
Daniel M. Zeitler
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Hyperbaric Oxygen ◽  
Salvage Therapy ◽  
Sudden Sensorineural Hearing Loss ◽  
Significant Difference ◽  
Group 2 ◽  
Hearing Outcomes ◽  
Group 1

Objective: We sought to evaluate hearing outcomes after salvage therapy with hyperbaric oxygen (HBO2) for the treatment of sudden sensorineural hearing loss (SSNHL). Study Design: Matched control retrospective case series. Setting: Tertiary neurotology referral center. Patients: Thirty-six patients (>18 years) diagnosed with SSNHL. Intervention: Patients received initial therapy with oral and/or intratympanic (IT) steroids with an incomplete response. Eighteen patients underwent salvage therapy with IT steroids and HBO2 (group 1). Eighteen matched controls underwent salvage therapy with IT steroids alone (group 2). Main outcome measures: The main outcome measure was improvement in pure tone average (PTA) and word recognition score (WRS). Complications as a result of therapy were also monitored. Results: There were no significant differences in age, gender, or hearing between the 2 groups ( P > .05). There was no significant difference in mean post-treatment PTA between group 1 (60.3 dB) and group 2 (53.2 dB). There were no significant difference in mean post-treatment WRS between group 1 (42%) and group 2 (51%). Serviceable hearing was defined as a minimum WRS of 50%. Thirty-three percent in group 1 and 42% in group 2 went from nonserviceable hearing to serviceable hearing ( P > .05). PTA and WRS change scores were not significantly affected by age, gender, form of initial treatment, or pre-treatment PTA and WRS. Conclusion: The present study demonstrated no significant difference in hearing outcomes between patients receiving salvage therapy with HBO2 and IT steroids compared to patients receiving IT steroids alone. Larger, prospective randomized trials are needed to better define the role of HBO2 as salvage therapy for SSNHL.

Evaluation of cranial tibial and extensor carpi radialis reflexes before and after anesthetic block in cats

2016 ◽  
Vol 19 (2) ◽  
pp. 105-109 ◽  
Author(s):  
Eduardo Alberto Tudury ◽  
Marcella Luiz de Figueiredo ◽  
Thaiza Helena Tavares Fernandes ◽  
Bruno Martins Araújo ◽  
Marília de Albuquerque Bonelli ◽  
...  
Keyword(s):  
Brachial Plexus Block ◽  
Neurologic Examination ◽  
Anesthetic Induction ◽  
Significant Difference ◽  
Before And After ◽  
Reflex Arc ◽  
Group 2 ◽  
Plexus Block ◽  
Extensor Carpi Radialis ◽  
Group 1

Objectives This study aimed to test the extensor carpi radialis and cranial tibial reflexes in cats before and after anesthetic block of the brachial and lumbosacral plexus, respectively, to determine whether they depend on a myotatic reflex arc. Methods Fifty-five cats with a normal neurologic examination that were referred for elective gonadectomy were divided into group 1 (29 cats) for testing the extensor carpi radialis reflex, and group 2 (26 cats) for testing the cranial tibial reflex. In group 1, the extensor carpi radialis reflex was tested after anesthetic induction and 15 mins after brachial plexus block with lidocaine. In group 2, the cranial tibial, withdrawal and patellar reflexes were elicited in 52 hindlimbs and retested 15 mins after epidural anesthesia. Results In group 1, before the anesthetic block, 55.17% of the cats had a decreased and 44.83% had a normal extensor carpi radialis reflex. After the block, 68.96% showed a decreased and 27.59% a normal reflex. No cat had an increased or absent reflex before anesthetic block. In group 2, prior to the anesthetic block, 15.38% of the cats had a decreased cranial tibial reflex and 84.62% had a normal response, whereas after the block it was decreased in 26.92% and normal in 73.08% of the cats. None of the cats had an increased or absent reflex. Regarding the presence of both reflexes before and after anesthetic block, there was no significant difference at 1% ( P = 0.013). Conclusions and relevance The extensor carpi radialis and cranial tibial reflexes in cats are not strictly myotatic reflexes, as they are independent of the reflex arc, and may be idiomuscular responses. Therefore, they are not reliable for neurologic examination in this species.

scholarly journals Keratinized Gingiva Determines a Homeostatic Behavior of Gingival Sulcus through Transudation of Gingival Crevice Fluid

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Maria Luiza P. Lagos ◽  
Adriana Campos Passanezi Sant'Ana ◽  
Sebastião Luiz Aguiar Greghi ◽  
Euloir Passanezi
Keyword(s):  
Tissue Fluid ◽  
Gingival Margin ◽  
Before And After ◽  
Group 2 ◽  
Shed Light ◽  
Group 1

Objective. To shed light on the role of KG, its influence on periodontal behavior was investigated.Methods. Tissue fluid transudation was assessed in alveolar mucosa (P1A), outer gingival margin (P1B), at entrance of (P2) and within gingival sulcus (P3), before and after chewing of fibrous food in 16 patients portraying ≥2 mm KG at one tooth (group 1), and <2 mm at another homologous tooth (group 2).Results. There was a significant increase in GCF after chewing at P1B and P3 in group 1 and at P1A in group 2 (t-test, ).Conclusions. The results suggest that KG plays a role in marginal periodontal homeostasis.

scholarly journals P1291PULMONARY HYPERTENSION VERSUS PULMONARY CONGESTION IN HAEMODIALYSIS PATIENTS IN RELATION TO INCREASED INTER DIALYTIC WEIGHT GAIN

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Magdy ElSharkawy ◽  
Lina Khedr ◽  
Ali Abdel Rahman ◽  
Ahmed El Shimy ◽  
Ahmed Shebl
Keyword(s):  
Pulmonary Hypertension ◽  
Statistical Significance ◽  
Dry Weight ◽  
Pulmonary Congestion ◽  
Significant Relation ◽  
Cross Sectional ◽  
Group I ◽  
Significant Difference ◽  
Group 2 ◽  
Group 1

Abstract Background and Aims Volume overload is considered as an important clinical problem in HD patients. It is associated with morbid situations such as pulmonary hypertension and lung congestion. to assess the effect of increased (IDWG) on pulmonary hypertension, and lung congestion. Method This observational cross sectional study was conducted at on 60 HD patients, that were divided into Group I: 30 patients with an IDWG &lt; 3.5% and, Group II: 30 patients with an IDWG &gt; 3.5% of their dry weight. Pulmonary artery pressure was measured by echo and patients classified according to PAP into mild, moderate and severe pulmonary hypertension. Lung congestion in all patients was measured by lung ultrasound and patients classified into minimal, mild, moderate and severe lung congestion. Results Our study showed that pulmonary hypertension prevalence was 30% while lung congestion was 100%. Patients with increased IDWG &gt; 3.5% (group 2) had pre HD higher PAP than those with IDWG &lt; 3.5% (group 1) and patients with IDWG &gt; 3.5% had more change in their PAP post HD session than those with IDWG &lt; 3.5% but no significant difference between the change after the HD session in both groups. HD duration is an important factor in PH development over years. There is a significant relation anemia and hypercalcemia with PH. Patients with more increased IDWG &gt; 3.5 % (group 2) had higher pulmonary congestion than those with IDWG &lt; 3.5% (group 1) and patients with IDWG &lt; 3.5% had more change in their lung congestion level after the HD session than those with IDWG &gt; 3.5% but no statistical significance between the change in both groups. There was a significant relation between HD therapy duration with pulmonary congestion measured prior to the session. Conclusion on the short term increased IDWG affect lung congestion more than pulmonary hypertension.

scholarly journals Saliva Contamination Effect on Shear Bond Strength of Self-etching Primer with Different Debond Times

2007 ◽  
Vol 77 (5) ◽  
pp. 901-906 ◽  
Author(s):  
Tamer Turk ◽  
Selma Elekdag-Turk ◽  
Devrim Isci ◽  
Fethiye Cakmak ◽  
Nurhat Ozkalayci
Keyword(s):  
Control Group ◽  
Group 4 ◽  
Contamination Effect ◽  
Significant Difference ◽  
Before And After ◽  
Group 3 ◽  
Bond Strengths ◽  
Group 2 ◽  
Saliva Contamination ◽  
Group 1

Abstract Objective: To evaluate shear bond strengths (SBSs) of a self-etching primer (SEP) following saliva contamination at different stages of bonding at debond times of 5, 15, and 30 minutes and 24 hours. Materials and Methods: Two-hundred forty human premolars were divided into four groups: group 1, uncontaminated; group 2, saliva contamination after priming; group 3, saliva contamination before priming; and group 4, saliva contamination before and after priming. Four subgroups according to debond times of 5, 15, 30 minutes and 24 hours were composed. Metal brackets were bonded with an SEP (Transbond Plus) and light-cure adhesives paste (Transbond XT). SBS values and the adhesive remnants were determined. Results: The highest SBS was obtained at a debond time of 24 hours for the control group. This was significantly different from the other groups. SBSs at 5, 15, and 30 minutes showed no significant difference from each other in the control group (P &gt; .05). Lowest SBSs were obtained at a debond time of 5 minutes for groups 1, 2, 3, and 4 (8.38, 7.10, 7.06, and 6.26 MPa, respectively) and were not significantly different from each other (P &gt; .05). SBSs at 24 hours were not significantly different from each other for groups 2, 3, and 4 (P &gt; .05). Significant differences were found in the adhesive remnant (P &lt; .001). Conclusions: SEP (Transbond Plus) may produce clinically acceptable bracket bonding after 5, 15, and 30 minutes from time of placement on the teeth, even with light and heavy saliva contamination.

scholarly journals Role of Intranasal Steroid in the Prevention of Recurrent Nasal Symptoms after Adenoidectomy

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Tamer S. Sobhy
Keyword(s):  
Nasal Obstruction ◽  
Saline Group ◽  
Controlled Study ◽  
Nasal Discharge ◽  
X Rays ◽  
Group I ◽  
Significant Difference ◽  
Intranasal Steroids ◽  
Group 2

Background. Intranasal steroid provides an efficient nonsurgical alternative to adenoidectomy for theimprovement of adenoid nasal obstruction.Objective. To demonstrate the role of intranasal steroid in the prevention of adenoid regrowth after adenoidectomy.Methods. Prospective randomized controlled study. Two hundred children after adenoidectomy were divided into 2 groups. Group I received postoperative intranasal steroid and group II received postoperative intranasal saline spray. Both medications were administered for 12 weeks postoperatively. Patients were followed up for 1 year. Followup was done using the nasopharyngeal lateral X-rays, reporting the degree of the symptoms.Results. Significant difference between both groups after 6 months and after 1 year. The intranasal steroid group had significantly lower score after 6 months and after 1 year as regards nasal obstruction, nasal discharge, and snoring than the intranasal saline group. 2 weeks postoperatively, there was no difference between both groups as regards nasal obstruction, discharge, or snoring. As regards lateral radiographs, there was statistically significant difference between both groups 1 year but not 6 months postoperatively.Conclusion. Factors influencing the outcome of intranasal steroids therapy in the prevention of adenoid regrowth have not been identified. However, this treatment may obtain successful results in children to avoid readenoidectomy.

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