scholarly journals Therapeutic effects of anthocyanin-rich Hibiscus sabdariffa L. extract on body mass index, lipid profile and fatty liver in obese-hypercholesterolaemic rat model

2019 ◽  
Vol 9 (1) ◽  
pp. 1 ◽  
Author(s):  
Liza Noordin ◽  
Wan Nurul Izzati Wan Mohamad Noor ◽  
Sabreena Safuan ◽  
Wan Amir Nizam Wan Ahmad
Keyword(s):  
Body Mass Index ◽  
Lipid Profile ◽  
Body Mass ◽  
Liver Enzymes ◽  
Normal Diet ◽  
Male Rats ◽  
Therapeutic Effects ◽  
Hibiscus Sabdariffa ◽  
Sprague Dawley ◽  
Group 2

Background: Hibiscus sabdariffa L. or Roselle, is one of the most common flower plants cultivated worldwide. Traditionally, it is claimed to reduce weight and cholesterol level. The aim of this study was to evaluate the effects of anthocyanin-rich Roselle aqueous extract on the physical, biochemical and histological changes in obese-hypercholesterolaemic rat model.Methods: Thirty Sprague-Dawley male rats were divided into five groups (n=6 per group). Group 1 is normal control (NC) rat that was fed with normal diet. The remaining rats (Group 2-5) were fed with commercial high-fat diet (HFD) for 6 weeks to induce obese-hypercholesterolaemic (OH) rat. After induction, the OH rats were divided into 4 groups: OH-Untreated group, OH-ARTE; OH treated with 300 mg/kg Roselle aqueous (anthocyanin-rich) and 1% trifluoroacetic acid extract (ARTE), OH-Orlistat; OH treated with 37 mg/kg orlistat and OH-Atorvastatin; OH treated with 10 mg/kg atorvastatin. After the 3 weeks intervention period, all rats were sacrificed. Body mass index, lipid profile and liver enzymes were evaluated. The liver section was subjected to hematoxylin and eosin staining for histopathological evaluation.Results: This study showed that 3 weeks administration of ARTE significantly reduced BMI, improved levels of lipid profile and liver enzymes, and histopathological changes of liver when compared to OH-untreated rats. The results were also comparable to the standard drugs.Conclusions: This study suggested that Roselle extract constitutes an effective and safe alternate treatment for obesity and hyperlipidaemia.

scholarly journals Study of body mass index (BMI) and serum lipid profile of patients at a tertiary hospital: a cross sectional study

2018 ◽  
Vol 6 (6) ◽  
pp. 2060
Author(s):  
Archana . ◽  
Vibhuti Agarwal ◽  
Naved Ahmad ◽  
Akash Gupta
Keyword(s):  
Body Mass Index ◽  
Lipid Profile ◽  
Body Mass ◽  
Tertiary Hospital ◽  
Cross Sectional Study ◽  
Study Data ◽  
Cross Sectional ◽  
Group 2 ◽  
Group 1

Background: Sedentary lifestyle have an impact on the prevalence and incidence of obesity related disorders and leads to the development of type 2 diabetes mellitus, dyslipidemias and metabolic disorders that aggravate the risk in the development of cardiovascular diseases (CVD).Methods: In our study, data of 220 subjects belonging to age group of 25 to 55 years were collected. Body mass index (BMI) was calculated as weight in kilograms divided by the square of height in meters. Subjects were categorized into two groups (BMI <25 and BMI ≥25). Serum was separated by centrifuging blood at 3000 rpm for 10 min and analyzed for lipid profile on Erba Chem 7 semi-auto analyzer.Results: In our present hospital based study we estimated the Lipid Profile in individuals categorized into two groups. (Group 1 BMI <25) and (Group 2 BMI ≥25), We found the values of Triglycerides, LDL and VLDL in Group 1 are lower as compared to Group 2.Conclusions: Our study showed positive correlation between lipid profile and obesity. Obesity is said to predispose individuals to metabolic syndrome associated diseases.

scholarly journals CORRELATION OF LIPID PROFILE & BODY MASS INDEX (BMI) OF PATIENTS AT A TERTIARY CARE HOSPITAL: A CROSS SECTIONAL STUDY

2019 ◽  
Vol 3 (8) ◽  
Author(s):  
Shorya Taliyan ◽  
Sandeep Kumar Yadav ◽  
Bharat Kumar Gupta
Keyword(s):  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Lipid Profile ◽  
Body Mass ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
Group 2 ◽  
Group 1

Background: Sedentary daily life have an impact on the prevalence and incidence of metabolic syndrome disorder and results in development of type 2 diabetes mellitus, Dyslipidemia and metabolic disorders that aggravate the risk in the development of cardiovascular diseases (CVD). Methods: In our study Data of 92 males and 112 females, from the age group of 25 to 55 years were selected from December 2018 to July 2019 in a cross sectional manner. Blood sample (3 ml) was collected from each subject. Serum was separated by centrifuging blood at 3000 rpm for 10 min and analyzed for lipid profile by Siemens Dimension RXL max, wet chemistry analyzer. Body mass index (BMI) was calculated as weight in kilograms divided by the square of height in meters. Results: In our hospital based study we estimated the lipid profile in individuals categorized into two groups. (Group 1 BMI <25) and (Group 2 BMI ≥25), we found the values of  Triglycerides, LDL and VLDL in Group 1 are lower as compared to Group 2 values for same analytes. Conclusion: Our study found positive correlation between lipid profile and obesity. Results of this cross sectional study again prove that, Obesity predisposes individuals to metabolic syndrome associated ailments. Keywords: BMI, Lipid Profile, Metabolic Syndrome, Obesity, Dyslipidemia

scholarly journals Effects of Triphala on Lipid and Glucose Profiles and Anthropometric Parameters: A Systematic Review

2021 ◽  
Vol 26 ◽  
pp. 2515690X2110110
Author(s):  
Wiraphol Phimarn ◽  
Bunleu Sungthong ◽  
Hiroyuki Itabe
Keyword(s):  
Body Mass Index ◽  
Body Weight ◽  
Blood Glucose ◽  
Waist Circumference ◽  
Lipid Profile ◽  
Body Mass ◽  
The Body ◽  
Current Evidence ◽  
Diabetic Patients ◽  
Anthropometric Parameters

Aim. The efficacy of triphala on lipid profile, blood glucose and anthropometric parameters and its safety were assessed. Methods. Databases such as PubMed, ScienceDirect, Web of Science, and Thai Library Integrated System (ThaiLIS) were systematically searched to review current evidence of randomized controlled trials (RCT) on triphala. RCTs investigating the safety and efficacy of triphala on lipid profile, blood glucose and anthropometric parameters were included. Study selection, data extraction, and quality assessment were performed independently by 2 authors. Results. Twelve studies on a total of 749 patients were included. The triphala-treated groups showed significantly reduced low-density lipoprotein-cholesterol, total cholesterol and triglyceride in 6 studies. Five RCTs demonstrated triphala-treated groups led to statistically significant decrease in body weight, body mass index and waist circumference of obese patients. Moreover, triphala significantly decreased fasting blood glucose level in diabetic patients but not in people without diabetes. No serious adverse event associated with triphala was reported during treatment. Conclusions. This review summarized a current evidence to show triphala might improve the lipid profile, blood glucose, the body weight, body mass index and waist circumference under certain conditions. However, large well-designed RCTs are required to confirm this conclusion.

scholarly journals Can Body Mass Index Affect Height Growth at Menarche among Girls Receiving Treatment for Early Puberty? A Retrospective Study in Korean Girls

Children ◽  
2022 ◽  
Vol 9 (1) ◽  
pp. 110
Author(s):  
Sun-Jin Lee ◽  
Sun-Young Kim ◽  
Minsun Kim
Keyword(s):  
Body Mass Index ◽  
Body Weight ◽  
Body Mass ◽  
Central Precocious Puberty ◽  
Early Puberty ◽  
Time Points ◽  
Height Gain ◽  
The Mean ◽  
Group 2 ◽  
Group 1

Gonadotropin-releasing hormone agonist (GnRHa) therapy is used to control puberty progression and it preserves height potential in patients with idiopathic central precocious puberty (ICPP). This study evaluated the correlation between weight and height gain at menarche following GnRHa treatment among girls with ICPP and relatively central early puberty (EP). We investigated height/weight trends and changes in height from diagnosis to menarche in girls with ICPP and EP treated with GnRHa. The mean difference in height (Δheight) from treatment cessation to menarche was 9.79 ± 3.53 cm. Girls were divided into girls with Δheight ≥ 9.79 cm (Group 1) and girls with Δheight < 9.79 cm (Group 2). Although near adult height was significantly higher in Group 1, the mean body mass index (BMI) and weight were significantly lower at diagnosis, treatment discontinuation, and menarche. The BMI and weight at the three time points were negatively correlated with height. Girls with higher BMI at all three time points had slower growth rates during the study period. Considering that BMI and body weight were closely related to Δheight, proper management of BMI and body weight of girls receiving early puberty treatment might contribute to growth during and after GnRHa treatment.

scholarly journals DIFFERENCES IN BODY MASS INDEX AND SERUM LIPID PROFILE AMONG VEGETARIANS & NON VEGETARIANS

2013 ◽  
Vol 2 (35) ◽  
pp. 6766-6771
Author(s):  
Suja P ◽  
Shrinidhi Shrinidhi ◽  
Prarthana K G ◽  
Bharath T
Keyword(s):  
Body Mass Index ◽  
Lipid Profile ◽  
Body Mass ◽  
Serum Lipid ◽  
Serum Lipid Profile

scholarly journals Serotonin Level and Lipid Metabolism Indices in Patients with Irritable Bowel Syndrome with Constipation Against the Background of Various Degrees of Obesity

2018 ◽  
Vol 25 (2) ◽  
Author(s):  
Vasyl Mishchuk ◽  
Galina Grygoruk
Keyword(s):  
Body Mass Index ◽  
Irritable Bowel Syndrome ◽  
Lipid Profile ◽  
Body Mass ◽  
Density Lipoprotein ◽  
Functional Constipation ◽  
The Body ◽  
Normal Body Mass Index ◽  
Serotonin Level ◽  
Irritable Bowel

Recent research shows that the number of diseases associated with obesity has been increasing. In obese persons, association with functional constipation is noted in 24.0% of cases, and obesity is recorded in 60.0% of patients with functional constipation. Among the possible mechanisms for the development of such a combination are changes in serotonin level in the blood, although the existing data are ambiguous and sometimes controversial.The objective of the study is to investigate the changes in serotonin level in the blood of obese patients in combination with constipation and its relationship with the lipid profile of the blood.Materials and methods. 63 patients with obesity in combination with irritable bowel syndrome with constipation (IBSc), 24 patients with normal body mass index and 10 practically healthy people were examined. 25 patients with obesity and constipation had a body mass index of 32.8±0.24kg/m2, 28 patients – 37.8±kg/m2, and 10 patients – 42.6±0.5kg/m2. In patients with irritable bowel syndrome without obesity, the body mass index was 21.7±0.4kg/m2. The blood serotonin level and lipid profile of the blood was determined in all patients.Results. It was deermined that in case of irritable bowel syndrome with constipation, serotonin level in the blood was reduced. In obesity with IBSc, the concentration of serotonin, on the contrary, was elevated. All patients with IBSc and obesity were marked an elevated level of total cholesterol and triglycerides. A direct correlation between high levels of triglycerides and serotonin concentration in serum of such comorbid patients was detected. The increase in the degree of obesity in the presence of IBSc was accompanied by a decrease in the concentration of cholesterol of high density lipoprotein. Patients with IBSc without excessive body weight had no such deviations.Conclusions. With an increase in the degree of obesity, serotonin level in the blood increases and the lipid blood spectrum worsens.

scholarly journals Metabolic changes after bariatric surgical procedures

2020 ◽  
Vol 2 (1) ◽  
pp. 14-31
Author(s):  
Mohammed Ahmed ◽  
Saad Hummady ◽  
Falih ALgazgoos
Keyword(s):  
Body Mass Index ◽  
Lipid Profile ◽  
Body Mass ◽  
Surgical Procedures ◽  
Bypass Surgery ◽  
Gastric Bypass Surgery ◽  
Glycosylated Hemoglobin ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Independent Effect

Introduction: Obesity is associated with diabetes, dyslipidemia and increased cardiovascular disease risks. Bariatric surgeries are one of the most reliable ways to treat obesity. Bariatric Surgical procedures started in Basra at 2009 and since then, thousands of surgeries had been made, mainly in Al-Sadr Teaching Hospital. Objective: To prospectively evaluate the short term effect of bariatric surgical procedures on body mass index (BMI), lipid profile and glycosylated hemoglobin (HbA1C) and compare the effects of various types of these surgical procedures. Methods: A 12-month prospective study on 73 patients who underwent three types of bariatric surgeries, laparoscopic sleeve gastrectomy surgery (LSG), laparoscopic REUX-EN-Y gastric bypass surgery (LRYGB) and minigastric bypass surgery (MGB). Body mass index (BMI), HbA1C, total cholesterol (TC), High-Density-Lipoprotein cholesterol (HDL), Low-Density-Lipoprotein cholesterol (LDL) and triglycerides (TG) levels were evaluated before surgery and at 3 and 6 months postoperatively. Results: All bariatric procedures show significant improvement in all parameters (increment in HDL, reduction in BMI, A1C, HDL, LDL, TC, TG) at 3 months that continue to improve more at 6 months postoperatively (p<0.001), however, bypass surgeries (LRYGB and MGB) has additional favorable independent effect on A1C and LDL seen at 6 months post operatively. Conclusion: All of the studied bariatric surgeries improve BMI, HbA1C and lipid profile significantly, however, bypass procedures have more effect on LDL and HbA1C that seem to be procedure related and independent from weight loss or other changes.

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