scholarly journals Acceptance for Human Papilloma virus vaccines, experience at tertiary care centre of northern india: a hospital-based survey

2019 ◽  
Vol 8 (5) ◽  
pp. 1907
Author(s):  
Manju Lata Verma ◽  
Uma Singh ◽  
Prachi Rai ◽  
Sabuhi Qureshi
Keyword(s):  
Hpv Vaccine ◽  
Tertiary Care ◽  
Uttar Pradesh ◽  
Categorical Variables ◽  
Continuous Variables ◽  
Tertiary Care Centre ◽  
Face To Face ◽  
Northern India ◽  
Ethical Approval ◽  
Medical University

Background: Acceptance of HPV vaccine is varying widely worldwide in   range of 10-70%. For increasing the acceptability for HPV vaccine, finding the obstacles and catering them diligently is required. The aim of the study was to find out acceptability rate for HPV vaccine in northern India and various obstacles and facilitators affecting acceptance of HPV vaccine.Methods: A questionnaire based descriptive study was done in the Department of Obstetrics and Gynecology of King George Medical University, Lucknow, Uttar Pradesh, India from June 2016 to June 2017.  Questionnaire was filled by doctor after taking face to face interview of individuals. Ethical approval was obtained from the Institutional Ethical Committee of the KGMU, Lucknow, Uttar Pradesh, India. (1689/Ethics/R cell/17) acceptability rate and various facilitators and obstacles for HPV vaccine were studied. For continuous variables mean with standard deviation was used. For categorical variables frequencies and percentages were used. IBM SPSS statistics applied.Results: A total of 302 cases were face to face interviewed, amongst which, 70 cases (23%) showed acceptability and 232 did not accept the vaccine. The most common obstacles were lack of knowledge and high monetary cost being the cause of nonacceptance in 48.3% and   33.6% of cases respectively.Conclusions: Higher level of awareness and knowledge about HPV vaccine and inclusion in government immunization programmed may increase acceptability.

scholarly journals Histomorphology of germ cell tumors at various anatomic sites: a 5 years study at a tertiary care centre

2021 ◽  
Vol 9 (10) ◽  
pp. 3079
Author(s):  
Manal A. Lateef ◽  
M. I. Lone
Keyword(s):  
Germ Cell ◽  
Malignant Tumors ◽  
Tertiary Care ◽  
Germ Cell Tumors ◽  
Cystic Teratoma ◽  
The Body ◽  
Categorical Variables ◽  
Continuous Variables ◽  
Tertiary Care Centre ◽  
Exact Test

Background: Germ cell tumors (GCTs) are a heterogeneous group of neoplasms, which occur in the gonads, and at extra gonadal sites of the body. The aim of the study was to observe the different histopathological patterns of various GCTs in the body at all possible sites and to know their IHC staining patterns.Methods: The study was conducted for a period of 5 years from 2015 to 2019 and was an observational study. The recorded data was compiled and entered in a spreadsheet and then exported to data editor of SPSS Version 20.0. Continuous variables were expressed as mean SD and categorical variables were summarized as frequencies and percentages. Graphically the data was presented by bar and pie diagrams Chi-square test or Fisher’s exact test was applied for comparing categorical values. P<0.05 was considered statistically significant. All p values were 2 tailed.Results: A total of 93 cases were analyzed and the mean age of the patients was 27.8 years. Mature cystic teratoma was the most common histopathological variant and was mostly seen in the ovaries. There was a difference in age predilection of benign and malignant tumors. Most of the malignant GCTs were gonadal while EGCTs were likely to be benign. MGCTs (mixed GCTs) were mostly testicular in origin with only one MGCT being extragonadal.Conclusions: Mature cystic teratomas were the most frequent GCTs with frequent site being in ovaries. Out 0f 18 EGCTs only 2 were malignant, rest all were mature cystic teratomas. 

scholarly journals Lymphocyte-Neutrophil Ratio in the Diagnosis of Tubercular Pleural Effusion in a Tertiary Care Centre: A Descriptive Cross Sectional Study

2021 ◽  
Vol 6 (2) ◽  
pp. 1517-1521
Author(s):  
Rajneesh Jha ◽  
Ram Kumar Mehata ◽  
Puru Koirala
Keyword(s):  
Pleural Effusion ◽  
Extrapulmonary Tuberculosis ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Categorical Variables ◽  
P Value ◽  
Care Hospital ◽  
Continuous Variables ◽  
Tertiary Care Centre ◽  
Cross Sectional

Introduction: Tuberculosis is a common infection in our community. Tubercular pleural effusion is the second most common form of extrapulmonary tuberculosis. Among the several causes of exudative pleural effusison tubercular remains the most common form in clinical practice. The aim of this study was to evaluate the significance of lymphocyte-neutrophil ratio(LN ratio) in cases of exudative effusion for diagnosis of tubercular effusion. Methods: This was a hospital based cross sectional studydone in Patients at tertiary care hospital from 1st September 2020 to 1st april 2021after taking ethical clearance from institutional reviw committee. Convienience samplingwas done. Statistical Analysis of data like percentages and frequencies  were used for categorical variables. Mean and SD (standard deviation) were used for describing continuous variables. Inferential statistical tools like Chi-Square test and Student’s t-test were used. P-value of <0.05 was considered statistically significant. Results: out of 200 cases 75% were tubercular pleural effusion and these cases were found have high levels of LN ratio (0.89 ± 0.11 for females and 0.97 ± 0.14 for males) and ADA (137.79 ± 44.61for females and 147.61 ± 51.64 for males) and more than 90% sensitivity and specificity of LN ratio and ADA level. Conclusion: Exudative pleural fluid L/N ratio >0.75 is an efficient means of diagnosing tuberculous pleural effusion and its combination with ADA level gives us more accuracy and surety about the diagnosis of tubercular pleural effusion.

scholarly journals A STUDY ON ETIOLOGICAL PROFILE IN ADULTS WITH ACUTE FEBRILE ENCEPHALOPATHY IN A TERTIARY CARE CENTRE IN EASTERN INDIA

2019 ◽  
Vol 3 (3) ◽  
Author(s):  
Indranil Sen ◽  
Sougata Bhattacharya ◽  
Sourav Bhakta ◽  
Sumit Ranjan
Keyword(s):  
Tertiary Care ◽  
Clinical Manifestations ◽  
Altered Mental Status ◽  
Clinical Syndrome ◽  
Categorical Variables ◽  
Public Health Issue ◽  
P Value ◽  
Continuous Variables ◽  
Tertiary Care Centre ◽  
Number Of Patients

Background: Acute febrile encephalopathy is a common clinical syndrome across the globe with the principal cause and manifestations differing according to the demographics. In developing nations like India primary central nervous system infections is the chief culprit. Aim: To identify the etiology of acute febrile encephalopathy and to document the clinical manifestations on presentation. The patients were followed up till discharge and outcome was analyzed in relation with etiology. Materials & Methods: This observational prospective study was done among 50 patients presenting with fever and altered mental status. History, clinical examination, biochemical investigations including cerebrospinal fluid analysis and neuroimaging was done to diagnose the cases individually. The statistical software SPSS version 2.0 was used for the analysis Categorical variables were expressed as number of patients or  percentage of patients and compared across the groups using Pearson’s Chi Square test for independence of attributes. Continuous variables was expressed as mean and standard deviation and compared across the groups using Kruskal Wallis Test. An alpha level of 5% was taken, i.e. if any p value is less than 0.05 it was considered as significant. Results: Out of these 50 patients 70% were due to CNS infections among which viral meningoencephalitis were the commonest cause. The other causes were leptospirosis, brain abscess, cerebral malaria, sepsis associated encephalopathy, acute disseminated encephalomyelitis, neuroleptic malignant syndrome. 14% of patients had sepsis associated encephalopathy and these patients had the highest mortality Conclusion: Acute febrile encephalopathy is a clinically heterogeneous syndrome with a number of causes. It is an important public health issue due to its steep mortality rate. Keywords: acute febrile encephalopathy, meningoencephalitis, mortality, sepsis associated encephalopathy

Prevalence and antibiogram of non-fermenting Gram-negative bacilli in blood stream infections: Study in a tertiary care centre, Western Uttar Pradesh, India

2021 ◽  
pp. 004947552097929
Author(s):  
Tarana Sarwat ◽  
Mariyah Yousuf ◽  
Ambreen S Khan ◽  
Dalip K Kakru ◽  
Renu Dutta
Keyword(s):  
Burkholderia Cepacia ◽  
Tertiary Care ◽  
Uttar Pradesh ◽  
Blood Stream ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Acinetobacter Baumanii ◽  
Blood Stream Infections ◽  
Antibiotic Susceptibility Pattern ◽  
Gram Negative

Non-fermenting Gram-negative bacilli (NFGNB) are emerging as important cause of blood stream infections. We aimed to determine the prevalence and antibiotic susceptibility pattern of NFGNB isolated from blood of patients with sepsis. We found, in 176 patients, the most common to be Pseudomonas aeruginosa (74) and Acinetobacter baumanii complex (39) followed by Stenotrophomonas maltophilia (16), Sphingomonas paucimobilis (6), Burkholderia cepacia (5) and Ochrobactrum anthropic (1). Generally, organisms showed a good sensitivity towards colistin, carbapenems and fluoroquinolones, whereas cephalosporins were ineffective.

scholarly journals Real world perspective of coronary chronic total occlusion in third world countries: A tertiary care centre study from northern India

2021 ◽  
Vol 73 (2) ◽  
pp. 156-160
Author(s):  
Krishna Santosh Vemuri ◽  
Bhupinder Kumar Sihag ◽  
Yashpaul Sharma ◽  
Krishna prasad Nevali ◽  
Rajesh Vijayvergiya ◽  
...  
Keyword(s):  
Real World ◽  
Chronic Total Occlusion ◽  
Third World ◽  
Tertiary Care ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Total Occlusion ◽  
Centre Study ◽  
Northern India ◽  
World Perspective

scholarly journals Transperitoneal Transvesical Laparoscopic Repair of Vesicovaginal Fistulae: Experience of a Tertiary Care Centre in Northern India

2013 ◽  
Vol 7 (2) ◽  
pp. 75-82 ◽  
Author(s):  
Vishwajeet Singh ◽  
Rahul J. Sinha ◽  
Seema Mehrotra ◽  
Dheeraj K. Gupta ◽  
Smita Gupta
Keyword(s):  
Laparoscopic Repair ◽  
Tertiary Care ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Northern India ◽  
Vesicovaginal Fistulae

Cost analysis and benefits of opt-out HIV testing at a tertiary care centre in northern India

2013 ◽  
Vol 25 (5) ◽  
pp. 341-347 ◽  
Author(s):  
Ranjana W Minz ◽  
Anju Khairwa ◽  
Ritu Aggarwal ◽  
Harwinder Kaur ◽  
Surjit Singh ◽  
...  
Keyword(s):  
Cost Analysis ◽  
Hiv Testing ◽  
Tertiary Care ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Northern India ◽  
Opt Out

scholarly journals HPV genotyping and risk factors for anal high-risk HPV infection in men who have sex with men from Toronto, Canada

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yoojin Choi ◽  
Mona Loutfy ◽  
Robert S. Remis ◽  
Juan Liu ◽  
Anuradha Rebbapragada ◽  
...  
Keyword(s):  
Risk Factors ◽  
High Risk ◽  
Hpv Vaccine ◽  
Hpv Infection ◽  
Categorical Variables ◽  
Genotype Distribution ◽  
Continuous Variables ◽  
Chi Square ◽  
Hpv Genotypes ◽  
Sex With Men

AbstractMen who have sex with men (MSM) are disproportionately affected by anal cancer, predominantly caused by high-risk (HR) human papillomavirus (HPV) infection. Currently, the nonavalent HPV vaccine provides coverage against nine HPV genotypes, including seven HR-HPV genotypes. Here, we characterize anal HR-HPV genotype distribution and associated risk factors in MSM from Toronto, Canada recruited between September 2010 and June 2012. Wilcoxon–Mann–Whitney test was used for continuous variables, Chi-square test was performed for categorical variables, and a multivariable model using logistic regression was created to assess for correlates of anal HR-HPV infection. A total of 442 MSM were recruited, with a median age of 45 (IQR 38–50) and an overall HPV prevalence of 82%. The prevalence of any HR-HPV infection was 65.3% and 50.7% in the HIV-positive and HIV-negative MSM, respectively. No participant tested positive for all genotypes covered by the nonavalent vaccine. HIV status (aOR 1.806; 95% CI 1.159–2.816), smoking (aOR 2.176; 95% CI 1.285–3.685) and the number of lifetime sexual partners (aOR 2.466; 95% CI 1.092–5.567) were independent risk factors for anal HR-HPV infection. Our findings will be useful to inform HPV vaccine rollout and HPV prevention strategies in Canadian MSM.

Ultrasound Employed to Detect Breast Lumps among Symptomatic Patients in Tertiary Care Hospital

2020 ◽  
Vol 10 (4) ◽  
pp. 296-300
Author(s):  
Ameet Jesrani ◽  
Pari Gul ◽  
Nida Khan ◽  
Seema Nayab ◽  
Fahmida Naheed
Keyword(s):  
Predictive Value ◽  
Imaging Modality ◽  
Tertiary Care ◽  
Ultra Sound ◽  
Categorical Variables ◽  
Breast Lesions ◽  
Care Hospital ◽  
Continuous Variables ◽  
Cross Sectional ◽  
Breast Lumps

Objective: To assess different pathological breast lesions in ultra sound in a subgroup of population. Study design and setting: It was a cross sectional study conducted at Bolan Medical Complex Hospital Quetta, Pakistan from June 2018 to January 2019. Methodology: Total 103 patients with breast swelling, pain and discharge were targeted. Gray scale and Doppler Ultrasound of breast followed by FNAC/biopsy of breast lesion was performed. Data presented as mean ± standard deviation for continuous variables and frequency with percentages for categorical variables. Results: Out of 48 clinically palpable lumps US detected all of 48 lumps and additionally 12 clinically non palpable masses were detected on US examination. Thus, overall sensitivity of ultrasound in detecting breast lumps was 100%. Fibroadenoma of the breast was diagnosed accurately in 80.3% of women. Ultrasound reliably differentiated cystic from solid breast masses (100%). The sensitivity of ultrasound for detecting breast carcinoma was 63.4% with a positive predictive value of 87.5%, a negative predictive value of 99.5% and accuracy of 58.33%. US findings most suggestive of benign lesions were oval or round shape in 88.3%, well defined margin in 84%, absent lobulation in 86.04% and wider than taller ratio in 90.69% of the cases.US findings of most predictive for malignancy were of irregular shape in 81.8%, ill-defined margin in 90.9% and length to height ratio in 63.6% of cases. Conclusion: Ultrasound is simple, cheap, safe and relatively accessible imaging modality for evaluation of breast pathologies. Due to its high sensitivity in diagnosing benign breast lesions particularly cystic lesions and fibroadenoma unnecessary interventions can be avoided

The Compliance of Prescribed Activity Restriction in Women at High Risk for Preterm Birth

2020 ◽  
Author(s):  
Ghamar Bitar ◽  
Anthony Sciscione
Keyword(s):  
Preterm Birth ◽  
High Risk ◽  
Medical Center ◽  
Compliance Rate ◽  
Tertiary Care ◽  
Prescribing Patterns ◽  
Categorical Variables ◽  
Continuous Variables ◽  
Activity Restriction ◽  
The Impact

Objective Despite lack of evidence to support efficacy, activity restriction is one of the most commonly prescribed interventions used for the prevention of preterm birth. We have a departmental policy against the use of activity restriction but many practitioners still prescribe it in an effort to prevent preterm birth. We sought to evaluate the rate and compliance of women who are prescribed activity restriction during pregnancy to prevent preterm birth. Study Design This was a single-site retrospective questionnaire study at a tertiary care, academic affiliated medical center. Women with a history of preterm delivery or short cervix were included. Once patients were identified, each patient was contacted and administered a questionnaire. We assessed the rates of activity restriction prescription and compliance. Secondary outcomes included details regarding activity restriction and treatment in pregnancy. Continuous variables were compared with t-test and categorical variables with Chi-square test. The value p < 0.05 was considered significant. Results Among the 52 women who responded to the questionnaire, 18 reported being placed on activity restriction by a physician, with 1 self-prescribing activity restriction, giving a rate of our primary outcome of 19 of 52 (36.5%). All women reported compliance with prescribed activity restriction (100%). Gestational age at delivery was not different in women placed on activity restriction. Conclusion This questionnaire suggests that approximately one in three high-risk women were placed on activity restriction during their pregnancy despite a departmental policy against its use. The 100% compliance rate in patients placed on activity restriction is a strong reminder of the impact prescribing patterns of physicians can have on patients. Key Points

Sign in / Sign up

Export Citation Format

Share Document