scholarly journals Abnormal semen parameters among males in infertile couples: a cross sectional study from a tertiary care centre

2020 ◽  
Vol 9 (8) ◽  
pp. 3398
Author(s):  
Jyoti Garg ◽  
Rachana Meena ◽  
Shailaja Shukla ◽  
Sunita Sharma ◽  
Riva Choudhury
Keyword(s):  
Semen Quality ◽  
Semen Analysis ◽  
Tertiary Care ◽  
Sperm Concentration ◽  
Semen Parameters ◽  
Medical Attention ◽  
Male Factor Infertility ◽  
Male Factor ◽  
Cross Sectional ◽  
Infertile Couples

Background: In India, the prevalence of primary infertility ranges from 3.9% to 16.8%. Male factor contributes 40-50% of this. Male factor infertility is indicated by decreased sperm concentration, reduced motility, vitality or abnormal sperm morphology. Semen analysis is the single most important investigation to detect male factor infertility. The aim of this study was to analyse the prevalence of abnormal semen parameters among males in infertile couples and their association with contributing factors.Methods: This cross-sectional hospital-based study was carried out in the Department of Pathology at Lady Hardinge Medical College and Smt. Sucheta Kriplani Hospital. A total of 400 cases were analyzed during a period of 6 months. Detailed history of the couple was taken. Semen analysis was done using automated semen analyzer (SQA-vision) after 3 days of abstinence according to the WHO 5th edition 2010 guidelines. The results were analysed using excel sheet and SPSS software.Results: In the present study, 122 cases (30.5%) out of 400 cases had abnormal semen parameters. Most common abnormality detected was asthenozoospermia (14.3%) followed by oligozoospermia (13.8%), azoospermia (10.5%) and teratozoospermia (10.5%). There was significant association of alcohol intake, obesity and trauma with abnormal semen parameters.Conclusions: Asthenozoospermia was the most common abnormality noted in this study. Lifestyle modifications along with timely medical attention in male partners of infertile couples can improve the semen quality.

scholarly journals A study of abnormal semen parameters in infertile couples in Assam, India

2019 ◽  
Vol 8 (3) ◽  
pp. 997
Author(s):  
Parija Juneja ◽  
Pranay K. Phukan ◽  
Debojit Changmai
Keyword(s):  
Semen Quality ◽  
Semen Analysis ◽  
Care Center ◽  
Tertiary Care ◽  
Sperm Concentration ◽  
Semen Parameters ◽  
Male Partners ◽  
Male Factor ◽  
Volume Viscosity ◽  
Infertile Couples

Background: The importance of male factor contribution to infertility is well recognised. Semen analysis is an indispensable diagnostic tool in the evaluation of the male partners of infertile couples.  Aim and objective of the study was conducted to determine the abnormalities in semen among male partners in infertile couples.Methods: Detailed history, examination and semen analysis was done. Semen samples were analysed for volume, viscosity, sperm concentration, motility, and morphology, according to WHO guidelines.Results: This study, done at a tertiary care center in north eastern India has demonstrated that abnormal semen quality is a major factor contributing to infertility in couples. Total number of participants were 94. Most of the male partners i.e. 65.96%, who came for infertility evaluation were between 30-39 years of age with 56.38% participants having abnormal semen parameters. The most common abnormality found was asthenozoospermia seen in 35.11% of cases followed by oligozoospermia seen in 25.53% of cases. Teratozoospermia and azoospermia were seen in 7.45% and 4.26% of cases respectively.Conclusions: Males contribute towards infertility in couples significantly. Abnormal semen pattern is a common cause. More research is needed to render more valuable and significant results regarding male infertility.

A STUDY OF ABNORMAL SEMEN PARAMETERS IN INFERTILE COUPLES IN BHAGALPUR, BIHAR

2021 ◽  
pp. 5-6
Author(s):  
Anshu Anshu ◽  
Usha Kumari ◽  
Debarshi Jana
Keyword(s):  
Semen Quality ◽  
Semen Analysis ◽  
Sperm Concentration ◽  
Semen Parameters ◽  
Who Guidelines ◽  
Male Partners ◽  
Male Factor ◽  
Obstetrics And Gynaecology ◽  
Volume Viscosity ◽  
Infertile Couples

Background: The importance of male factor contribution to infertility is well recognised. Semen analysis is an indispensable diagnostic tool in the evaluation of the male partners of infertile couples. Aim and objective of the study was conducted to determine the abnormalities in semen among male partners in infertile couples. Detailed history, examination and Methods: semen analysis was done. Semen samples were analysed for volume, viscosity, sperm concentration, motility, and morphology, according to WHO guidelines. This study, done at Obstetrics and Gynaecology Department of Results: JLNMCH, Bhagalpur, Bihar has demonstrated that abnormal semen quality is a major factor contributing to infertility in couples. Total number of participants were 94. Most of the male partners i.e. 65.96%, who came for infertility evaluation were between 30-39 years of age with 56.38% participants having abnormal semen parameters. The most common abnormality found was asthenozoospermia seen in 35.11% of cases followed by oligozoospermia seen in 25.53% of cases. Teratozoospermia and azoospermia were seen in 7.45% and 4.26% of cases respectively. Males contribute towards infertility in Conclusions: couples signicantly. Abnormal semen pattern is a common cause. More research is needed to render more valuable and signicant results regarding male infertility

scholarly journals Pattern of semen analysis at andrology lab of Bangabandhu Sheikh Mujib Medical University: Findings and the shortcomings to overcome

2016 ◽  
Vol 7 (2) ◽  
pp. 103
Author(s):  
Shakeela Lshrat ◽  
Parveen Fatima ◽  
Nurjahan Begum ◽  
Afruna Rahman Diti
Keyword(s):  
Primary Care ◽  
Semen Analysis ◽  
Sperm Concentration ◽  
Descriptive Study ◽  
Semen Parameters ◽  
Who Guidelines ◽  
Male Factor ◽  
Infertile Men ◽  
Infertile Couples ◽  
Medical University

<p><strong>Background:</strong> The Infertility wing dept. of gyne &amp; obst at BSMMU provides services to the infertile couples who are referred from primary care levels and who cannot afford the expensive private facilities. The semen analysis is performed for the male partners of infertile couples at the Andrology Lab of BSMMU for detecting male factor abnormalities. <strong>Objectives:</strong> The objective of the study is to find out the pattern of semen parameters in our population and to find out the frequency and type of abnormal semen parameters. <strong>Methods:</strong> This is a retrospective descriptive study of the semen analysis performed at the Andrology Lab of BSMMU during the year 2011. A total of 200 consecutive samples were analysed. The procedure and reference values were according to the WHO guidelines 1999. <strong>Results:</strong> Semen parameters were abnormal in 38.5% of semen analysis. Severe male factor abnormality (azospermia and severe oligospermia combined) was in 28%. Sperm concentration had the highest variability followed by motility and morphology respectively in the n01moozospermic males. <strong>Conclusion:</strong> Severe oligospennia and azospermia are the most common abnormali­ties among the infertile men presenting at the Infertility unit ofBSMMU. It is recommended that the service at the Infertility wing of BSMMU should be more focused on these male factor abnormalities.</p>

scholarly journals Iranian temporal changes in semen quality during the past 22 years: A report from an infertility center

2020 ◽  
Author(s):  
Serajeddin Vahidi ◽  
Mohammad Reza Moein ◽  
Fatemeh Yazdinejad ◽  
Saeed Ghasemi-Esmailabad ◽  
Nima Narimani
Keyword(s):  
Semen Quality ◽  
Semen Analysis ◽  
Sperm Concentration ◽  
Cross Sectional Study ◽  
Temporal Changes ◽  
Systemic Review ◽  
Semen Parameters ◽  
Cross Sectional ◽  
Clinical Center ◽  
Group 2

Background: Despite numerous reports about temporal changes in semen quality from all over the world, the debates continue. The latest systemic review has shown an overtime decrease in semen quality worldwide. Objective: To assess the temporal changes in the semen quality among Iranian population referred to an infertility center. Materials and Methods: In this retrospective cross-sectional study, semen parameters including concentration, motility, and morphology were compared between Iranian men reffered to Research and Clinical Center for Infertility, Yazd between 1990 to 1992 (group 1, n = 707) and 2010 to 2012 (group 2, n = 1108). Demographic characteristics and semen analysis were collected from the records. The effect of age on semen parameters was also investigated. Results: Despite the increase in sperm concentration l in group 2, sperm with normal morphology decreased significantly (p < 0.001). Grade-A motility decreased (p < 0.001), grade B motility increased (p < 0.001), and grade C and D motile sperm remained constant (p = 0.303 and p = 0.315, respectively). Also, no significant correlation between the age and semen parameters were observed. Conclusion: This study showed inconsistent temporal changes in the participant semen quality. Significant temporal decline were obtained between various semen parameters, sperm morphology and grade A motility. These results should be further evaluated by larger studies in the future. Key words: Infertility, Semen quality, Temporal changes.

scholarly journals Regional Differences in Semen Quality Between Guangzhou and Hong Kong in South China: A Cross-Sectional Study

2020 ◽  
Author(s):  
Xiao Shi ◽  
Carol Pui Shan Chan ◽  
David Yiu Leung Chan ◽  
Song Quan ◽  
Tin-Chiu Li
Keyword(s):  
Hong Kong ◽  
South China ◽  
Semen Quality ◽  
Semen Analysis ◽  
Sperm Concentration ◽  
Additive Models ◽  
Semen Parameters ◽  
Male Population ◽  
Cross Sectional ◽  
Matching Design

Abstract Background: The geographic variation in semen quality has been reported in many countries. However, the situation in China is still unknown. To answer this question, we examined the variation in semen parameters between two cities in south China: Guangzhou (GZ) and Hong Kong (HK).Methods: Semen analysis data of 13507 subjects from GZ and 1106 subjects from HK were retrospectively analysed. In order to control for referral bias, we selected two well-defined subpopulations, namely, subpopulation Ⅰ: male partners of women with an underlying cause of subfertility, which is assumed to be similar to the general male population; subpopulation Ⅱ: normozoospermic men, which is assumed to represent men with normal spermatogenesis, sperm maturation and sperm transportation. In addition, we have also chosen to control for two well-recognized confounding variables, namely, age and abstinence time by using a case matching design and generalised additive models (GAM).Results: In using the case matching design, subjects from different cities with similar age and abstinence time were matched. The results of the paired T test showed that sperm concentration and motility of subjects in HK were significantly lower than that of subjects in GZ in both subpopulation Ⅰ and Ⅱ (P < 0.05); on the other hand, the sperm morphology of subjects in HK was significantly lower than that of subjects in GZ in subpopulation Ⅰ (P < 0.05) but not in subpopulation Ⅱ (P > 0.05).The results of GAM model showed that the sperm parameters were variated by age and/or abstinence time, however, the sperm concentration, motility and morphology of subjects in HK were significantly lower than that of subjects in GZ in both subpopulation Ⅰ and Ⅱ (P < 0.05). Conclusions: The semen quality of subjects in HK was significantly worse than that of subjects in GZ, which may be caused by environmental and lifestyle factors, given that the study subjects in both cities of the present study are of the same ethnic origin.Trial registration: Not applicable.

scholarly journals Semen analysis and sperm function parameters in patients with infertility in Navi Mumbai and Panvel region

2019 ◽  
Vol 8 (11) ◽  
pp. 4169
Author(s):  
Surekha Bhalekar ◽  
Shweta Ganorkar ◽  
Hemant Bhalekar ◽  
Prakash Roplekar
Keyword(s):  
Sperm Count ◽  
Semen Analysis ◽  
Male Partner ◽  
Age Groups ◽  
Clinical Problem ◽  
Semen Parameters ◽  
Sperm Function ◽  
Male Factor Infertility ◽  
Male Factor ◽  
Cross Sectional

Background: Although semen analysis is routinely used to evaluate male partner in infertile couples, infertility and problems of impaired fecundity have been a concern through ages and is also a significant clinical problem today, which affects 8-12% of couples worldwide. Aim of the study was to study different semen parameters in male factor infertility (MFI) and thus increasing the awareness regarding same.Methods: This is cross sectional study conducted between period of September 2016 to December 2018. Semen of 150 patients were studied and results were analysed as per recent WHO (2010) criteria.Results: The present study included 150 patients whose age ranged from 24 to 51 years. Patients were divided into different age groups and sperm count was studied in each group. Abnormal sperm morphology was studied with respect to sperm head, neck, tail defects and combined defects. Sperm deformity index (SDI) and Teratozoospermic index (TZI) were calculated. Other parameters including semen volume, pH, liquefaction time, sperm vitality and motility were also studied which showed significant variations. Conclusions: Although semen analysis is first and most informative investigation for evaluation of male factor infertility, studying individual semen parameters and sperm function and increasing its awareness in general population especially in developing countries is equally important. Besides, it is necessary to acknowledge its limitation with respect to collection, processing, evaluation and biological variation of samples. Also, a normal semen analysis may not prove successful fertility potential of an individual.

scholarly journals Intracytoplasmic sperm injection: state of the art in humans

Reproduction ◽  
2017 ◽  
Vol 154 (6) ◽  
pp. F93-F110 ◽  
Author(s):  
G D Palermo ◽  
C L O’Neill ◽  
S Chow ◽  
S Cheung ◽  
A Parrella ◽  
...  
Keyword(s):  
Intracytoplasmic Sperm Injection ◽  
Poor Prognosis ◽  
State Of The Art ◽  
Semen Analysis ◽  
Reproductive Technology ◽  
Male Factor Infertility ◽  
Male Factor ◽  
Current Application ◽  
Infertile Couples ◽  
The Impact

Among infertile couples, 25% involve both male and female factors, while male factor alone accounts for another 25% due to oligo-, astheno-, teratozoospermia, a combination of the three, or even a complete absence of sperm cells in the ejaculate and can lead to a poor prognosis even with the help of assisted reproductive technology (ART). Intracytoplasmic sperm injection (ICSI) has been with us now for a quarter of a century and in spite of the controversy generated since its inception, it remains in the forefront of the techniques utilized in ART. The development of ICSI in 1992 has drastically decreased the impact of male factor, resulting in millions of pregnancies worldwide for couples who, without ICSI, would have had little chance of having their own biological child. This review focuses on the state of the art of ICSI regarding utility of bioassays that evaluate male factor infertility beyond the standard semen analysis and describes the current application and advances in regard to ICSI, particularly the genetic and epigenetic characteristics of spermatozoa and their impact on reproductive outcome.

scholarly journals Semen quality pattern and age threshold: a retrospective cross-sectional study of 71,623 infertile men in China, between 2011 and 2017

2019 ◽  
Vol 17 (1) ◽  
Author(s):  
W. N. Li ◽  
M. M. Jia ◽  
Y. Q. Peng ◽  
R. Ding ◽  
L. Q. Fan ◽  
...  
Keyword(s):  
Semen Quality ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Cross Sectional Study ◽  
Semen Parameters ◽  
Sectional Study ◽  
Joinpoint Regression ◽  
Cross Sectional ◽  
Progressive Motility ◽  
Infertile Men

Abstract Background The aim of this study was to provide information on the semen quality pattern of infertile men and age thresholds for semen parameters in China. Methods This was a retrospective cross-sectional study investigating 71,623 infertile men from the Reproductive and Genetic Hospital of CITIC Xiangya in Hunan, China, from 2011 to 2017. The Kruskal-Wallis test, Mann-Kendall test, linear regression model and joinpoint regression were used. Results Although erratic changes were observed in the median semen parameters (sperm concentration 40.1–52.1 × 106/ml, total sperm count 117.8–153.1 × 106, sperm progressive motility 33.4–38.1%) during the 7 years of observation, no significant decrease in semen quality was found, and 47.88% of infertile men showed normal semen parameters according to the World Health Organization (WHO) criteria. According to the joinpoint regression analysis, sperm progressive motility appeared to decrease earlier than the sperm concentration and total sperm count (at 28, 58, and 42 years of age, respectively). Conclusions There is no evidence of a deterioration in semen quality among infertile men in Hunan, China. Semen parameters decreased with increasing age, with turning points noted at different ages. Semen parameters are not absolute evidence for the assessment of male fertility potential. Therefore, we believe that, among semen parameters, the sperm concentration is the best predictor of fertility for ART, followed by motility. Decreased sperm motility may affect natural pregnancy, but it is not necessary for successful IVF.

scholarly journals Randomized Clinical Trial: Effect of Walnuts on Semen Parameters and Male Fertility (P18-042-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Wendie Robbins ◽  
Howard Kim ◽  
Justin Houman ◽  
Geng-Wei Lee
Keyword(s):  
Clinical Trial ◽  
Los Angeles ◽  
Randomized Clinical Trial ◽  
Sperm Motility ◽  
Clinical Care ◽  
Sperm Concentration ◽  
Nutritional Supplement ◽  
Semen Parameters ◽  
Male Factor Infertility ◽  
Male Factor

Abstract Objectives Infertility affects ∼8–12% of couples worldwide with ∼40% attributed to male factors. Recent studies suggest a role for paternal diet in fertility. Walnuts contain a variety of nutrients essential in the development of spermatozoa. We conducted a randomized clinical trial (RCT) to determine if consumption of walnuts improves semen parameters and fertility in men seeking clinical care for male factor infertility. Methods This was a two arm, single blind, RCT. The comparison groups both received usual care for male factor infertility. One group added 42 gm/d walnuts to their diet, and the other group added a daily nutritional supplement recommended for male reproductive health. Participants (n = 75) were enrolled at an infertility clinic located in a large metropolitan medical center. Eligibility was determined by history, physical exam, and lab tests collected as part of clinical care. Research measures included semen analysis and blood sample at baseline and 3 months; ASA24 dietary recall at baseline, 2 and 3 months; and fertility report at 3 months and 1 year. Results Age range was 27 to 61 years (39.7 ± 7.0); BMI range 19.6 to 46.9 (26.8 ± 4.5); participant race was Asian 26.2%, White 44.3%, Hispanic White 16.4%, Black 8.2%, other 4.9%. Baseline sperm concentration was 39.4 ± 30 million per ml; sperm motility 31.1 ± 23.4%; and progressive motility 21.2 ± 15.8%. At 3 months, the walnut group demonstrated increased sperm motility and concentration, P = .04 and P = .07, respectively, whereas no significant changes from baseline were found in the nutritional supplement group. Both groups showed improved sperm morphology, P < .03. Preliminary data from the subset of men with 1-year follow-up data shows higher frequency of pregnancy in the walnut group compared to nutritional supplement, although not statistically significant, P = .09. We continue to follow the remaining participants until their 1-year fertility report. Conclusions This RCT demonstrated a beneficial effect of adding walnuts to the diet on sperm motility and morphology in men seeking care for infertility. Preliminary fertility data suggests walnuts may enhance the probability of pregnancy for men with male factor infertility. Funding Sources Center for Occupational and Environmental Health, University of California, Los Angeles; California Walnut Commission.

scholarly journals ASSOCIATION OF VARICOCELE WITH OLIGOSPERMIA AND AZOSPERMIA

1969 ◽  
Vol 3 (2) ◽  
pp. 303-307
Author(s):  
NAIK ZADA ◽  
SHAFI ULLAH KHAN ◽  
RIAZ AHMAD KHAN
Keyword(s):  
Sperm Count ◽  
Human Subjects ◽  
Semen Analysis ◽  
Cross Sectional Study ◽  
Semen Parameters ◽  
Male Factor ◽  
Cross Sectional ◽  
Seminal Parameters ◽  
The Mean ◽  
Age Range

OBJECTIVE: To determine the frequency of abnormal semen parameters among patients presenting withvaricocele1METHODS:It was a descriptive cross-sectional study conducted at the Department of Urology Institute ofkidney diseases Hayat Abad Medical Complex Peshawar and Cenna hospital Saidu Sharif Swat. The studywas carried out on 139 human subjects with clinical evidence of varicocele between age range of 15-45years.The diagnosis of varicocele was based on palpable and/or visible scrotal lump of testicular veins(pampiniform plexus) and was diagnosed on the basis of clinical examination. Semen analysis was carriedout in all these patients and information wascollected on pre designed proforma.RESULTS:The study included a total of 139 patients with varicocele. The mean age of patient was 30 years(15-45) among the patients having symptoms of varicocele. The Mean ±SD for duration of varicocelesymptoms was 9.32 ± 9.70 months. 6.5% (n=9) patients were having azoospermia and 20.1% (n=28)patients had oligozoospermia.CONCLUSION: Patients with varicocele have poor seminal parameters in terms of sperm count i.e.oligozoospermia and azoospermia responsible for male factor infertility in majority ofcases.KEYWORDS:varicocele;seminal parameters;sperm count, infertility

Sign in / Sign up

Export Citation Format

Share Document