scholarly journals Histopathological patterns of head and neck lesions - a two year retrospective hospital based study

2017 ◽  
Vol 5 (4) ◽  
pp. 1282 ◽  
Author(s):  
Mahima Sharma ◽  
Anuja Sharma ◽  
Shivani Gandhi ◽  
Arvind Khajuria ◽  
K. C. Goswami
Keyword(s):  
Head And Neck ◽  
Neck Region ◽  
Base Line ◽  
Age Group ◽  
Female Ratio ◽  
Head And Neck Region ◽  
Specific Data ◽  
Graduate Department ◽  
Male Female Ratio ◽  
Age Range

Background: Head and neck lesions include a spectrum of pathological lesions ranging from simple benign to highly malignant entities. These lesions contribute significantly to morbidity and mortality of patients. The aim of this study was to determine the histological patterns of head and neck lesions, both non- neoplastic and neoplastic and to analyse the data in relation to age, gender, topography.Methods: A two year retrospective study was conducted in the Post Graduate Department of Pathology, ASCOMS and Hospital and histopathological data pertaining to all head and neck lesions was reviewed. Each case was analysed with respect to age, gender, site and histological type.Results: One hundred and forty-five cases from the head and neck region were analysed during this two-year period. Age range was from 3 months to 85 years with maximum cases in the age group of 21-50 years (51.03%). The Male: Female ratio was 1.37:1. In our study, 53.79% benign, 24.13% inflammatory and 22.06% malignant cases were recorded. Maximum number of benign lesions was in the age group of 21-50 years. Malignancies were noted to be higher in ages 51 years and above.  Squamous cell carcinoma was the most common malignancy observed.Conclusions: We conclude that site specific data like this is helpful in evaluating patterns of head and neck lesions and augment the base line data of institute and the region.

scholarly journals Epidemiological Profile of the Head- Neck Pathologies in a Peripheral Referral Institute

2019 ◽  
Vol 27 (2) ◽  
pp. 113-120
Author(s):  
Sabyasachi Ghosh ◽  
Tarak Nath Saha ◽  
Indranil Sen
Keyword(s):  
Head And Neck ◽  
Histopathological Examination ◽  
Neck Region ◽  
Head And Neck Cancers ◽  
Base Line ◽  
Age Group ◽  
Female Ratio ◽  
Male Female Ratio ◽  
Epidemiological Profile ◽  
Head Neck

Introduction   Head and neck lesions encompass a multitude of disorders which can be broadly classified into two groups: Benign and Malignant. Overall 57.5% of global head and neck cancers comes from Asia itself and India alone constitutes 30% of it. Therefore, it is of prime essence that need based and coordinated research for understanding the threats to the nation from chronic diseases such as head and neck cancers and ways to defy such threats should gain the utmost importance. The present study attempts to present the epidemiological profile of the patients attending a peripheral referral institute of this state with head-neck pathologies and has undergone a histopathological examination of their lesions within a period of three years period (2016-18) based on the histopathological evidences. Materials and Methods The accumulated data regarding the aforesaid patients as per records of the histopathological reports available in the Department of Pathology was used as the primary material and the interrelation of different epidemiological parameters were studied using the statistical methods Results Six hundred and eighty seven cases from the head and neck region were analysed during this three-year period. Age range was from 3 years to 96 years with maximum cases in the age group of 20-29 years (16.1%). The Male: Female ratio in our study was 1.34:1 (Males 394, Females 293). In this study, 38.8% benign, 32.46% malignant, 25.32% inflammatory and 3.3% congenital cases were recorded. Maximum number of benign lesions was in the age group of 10-39 years. Malignancies were noted to be higher in ages 40 years and above. Squamous cell carcinoma was the most common malignancy observed. Conclusion  Specific data obtained like this from histopathological records is helpful in evaluating patterns of head and neck lesions and augment the base line data of institute and the region.

scholarly journals The role of immunohistochemistry for diagnosing undifferentiated malignancy in the head and neck region

2019 ◽  
Vol 10 (1) ◽  
pp. 48-53
Author(s):  
Mohammad Sowkat Hossain ◽  
S M Mahbubul Alam ◽  
Sk Md Jaynul Islam ◽  
Wasim Selimul Haque ◽  
Shamoli Yasmin
Keyword(s):  
Head And Neck ◽  
Soft Tissues ◽  
Histopathological Examination ◽  
Malignant Neoplasm ◽  
Cervical Lymphadenopathy ◽  
Neck Region ◽  
Histopathological Diagnosis ◽  
Female Ratio ◽  
Head And Neck Region

Background: Undifferentiated tumours in the head and neck region are not uncommon. They can arise from different sites like in mucosa as well as in salivary glands, soft tissues or lymph nodes. Histopathological examination plays a central role in the diagnosis but difficulties arise with some tumours which are poorlydifferentiated due to their high inter- and intra-observer variability. In those cases, immunohistochemistry has greatly assisted to diagnose the tumours that cannot be accurately identified using routine histopathological procedures. The correct histopathological diagnosis is essential especially in case of malignant tumourwhere subsequent specific therapy is required. The aim of this study was to determine the role of immunohistochemistry for diagnosing undifferentiated malignancy in the head and neck region. Methods: This cross-sectional study was conducted during July 2014 to June 2015. A total of 35 Bangladeshi patient’s specimens of head and neck swelling were collected from two renowned laboratories in Dhaka city.These cases were diagnosed as undifferentiated tumour in histopathological examination.Standard protocol was followed for immunohistochemistry.Then primary immunohistochemical panel which included the markers for Epithelial CK (AE1/AE3),mesenchymal marker (Vimentin) and lymphoid marker (LCA) were used.The cases which were not resolved by primary immunohistochemistry panel, the second panel was applied for further sub classification (Desmin, Chromogranin, CK20, CEA, CD20, CD30, HMB45, NSE). Based on interpretation of immunohistochemical findings final diagnoses were made.Data analysis was performed using the Statistical Package for the Social Sciences for Windows version 22.0 (SPSS, Chicago, Illinois, USA). Results: A total of 35 undifferentiated tumorsof head-neck region were studied.The mean age was 46.3±17.6 years and male to female ratio was 4.8:1. The majority 13 (37.1%) patient had cervical lymphadenopathy, 11 (31.4%) had neck mass and 4(11.4%) had in nasal/sinonasal mass.Regarding histopathologicalcell types, round cell was 21 (60.0%), spindle cell 6 (17.1%), pleomorphic cells 6(17.1%) and epithelioid cells 2(5.7%). In initial histopathological examination, majority 25(71.4%) were undifferentiated malignant neoplasm, 8(22.8%) were metastatic undifferentiated carcinoma, 1(2.9%) was pleomorphic sarcoma and the remaining 1(2.9%) had malignant adnexal tumour. By application of immunohistochemistry, most (33, 94.3%) of the cases were resolved and the two cases remained unresolved. Among the resolved cases majority (15, 45.5%) were lymphoma, 4(12.1%) were metastatic carcinoma, 3(9.1%) were Ewing’s sarcoma and malignant melanoma were found in 3(9.1%) cases. Conclusion: This study supports that the immunohistochemical technique has a fundamental role in the investigation of undifferentiated tumour origin, to determine the correct guidance for treatment and improving the prognosis for head and neck tumour patients. Birdem Med J 2020; 10(1): 48-53

scholarly journals Basal Cell Carcinoma of the Head and Neck Region: An Analysis of 171 Cases

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Omer Sefvan Janjua ◽  
Sana Mehmood Qureshi
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Basal Cell ◽  
Neck Region ◽  
Margin Status ◽  
Anatomical Site ◽  
Female Ratio ◽  
Head And Neck Region ◽  
Malignant Skin Tumors

Objective. To analyze the pattern of presentation of basal cell carcinoma (BCC) and margin status for excised specimens in the head and neck region.Study Design. Retrospective cross-sectional.Duration of Study.January 2009 to December 2011.Methodology. The database of the pathology department was searched to identify records of all malignant skin tumors that underwent standard excision with margins. Out of these records, tumors with a diagnosis of BCC in the head and neck region were retrieved and separated. Age, gender, anatomic location, pattern of tumor, and margin status were noted.Results. A total of 171 cases of BCC from various sites of head and neck were retrieved. Male to female ratio was 1.4 : 1. The age ranged from 22 to 90 years. Seventy-six cases presented on right side, 79 on left, and 16 were in the midline. Most common anatomical site was the nose followed by the cheek. Nodular lesions were the most common (46.2%) followed by pigmented variety (18.7%). Margins were clear in 77 (45.1%) cases, involved in 86 (50.2%) cases, and close in 8 (4.7%) cases.Conclusion. Nose was the most common site followed by the cheek. Nodular and pigmented varieties were the most frequent and margins were involved in more than fifty percent of the cases.

scholarly journals EVALUATION OF PRIMARY EXTRANODAL NON-HODGKIN LYMPHOMA: A RECORD BASE STUDY

2019 ◽  
Vol 3 (2) ◽  
Author(s):  
Dr. Bipin Gandhi
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
Head And Neck ◽  
Neck Region ◽  
The Body ◽  
Age Group ◽  
Cervical Lymph Nodes ◽  
Head And Neck Region ◽  
Common Diagnosis ◽  
Common Group

INTRODUCTION: Lesions in head and neck have always been a diagnostic dilemma for a pathologist and a treating clinician. Being on the exposed part of body, they become cosmetically unacceptable. These include lesions arising from the regional group of lymph nodes. Most commonly lymphadenopathy is a common clinical presentation. The diagnostic probability ranges from infections to developmental abnormalities, from inflammatory to malignant lesions. None the less all the lesions in lymph nodes of the head and neck region cannot be limited to a particular age group and gender. Routine staining procedures like PAP, Giemsa, Field and even H & E has been used to clinch the pathogenesis of the lesion. It can be said without any fear of contradiction that FNAC is certainly a very important tool for an early diagnosis of not only head and neck lesions but also other lesions elsewhere in the body. MATERIAL AND METHODS: This is a comparative study which was conducted in the department of pathology. The patients were subjected to detailed history and thorough clinical examination according to the working proforma. Patients were subjected to FNAC after written informed concent. The slides were stained using PAP, Giemsa and H&E stain and examined for underlying pathology. A detailed gross examination was done and 3-15 sections were selected from the representative areas for routine paraffin sections.  RESULTS: Amongst the total of 296 patients aspirated, 127 were from Lymph Nodes of head and neck region. Cervicallymph nodes were the most common group of lymph nodes aspirated, followed by submandibular and submental lymph nodes. Age wise tabulation shows maximum frequency of inflammatory lesions at younger age, of  which reactive hyperplasia was more common in pediatric age group and tuberculous lesions were more common in 20-40years of age. CONCLUSION: Cervical lymph nodes were the most common group of lymph nodes aspirated, followed by submandibular and submental lymph nodes. Reactive lymphadenitis is the most frequent diagnosis amongst the lymph node lesions and tuberculous lesions was the second most common diagnosis amongst all the lymph node lesions. 35 cases out of 127, as tuberculous lymphadenitis. Histopathology correlation could be done in 36 cases, of which 32 were found be correctly diagnosed in cytology.

scholarly journals Prevalence of head and neck tumours in Calabar, South Eastern Nigeria

2016 ◽  
Vol 7 (3) ◽  
pp. 123-126 ◽  
Author(s):  
Okezie Obasi Kanu ◽  
Martin A. Nnoli ◽  
Chinyere A. Asoegwu
Keyword(s):  
Head And Neck ◽  
Neck Region ◽  
The Body ◽  
Slight Variation ◽  
Head And Neck Tumours ◽  
Female Ratio ◽  
Tumor Registry ◽  
Head And Neck Region ◽  
Head And Neck Malignancies ◽  
South Eastern

Background: Malignancies in the head and neck region though relatively rare, compared to other regions of the body, they contribute significantly to morbidity and mortality in affected patients. In Nigeria, the burden of managing head and Neck malignancies is enormous and there is yet to be a unified record of nation-wide incidence of malignancies involving the head and neck region despite the fact the head and neck malignancies have been diagnosed and documented since the 1960’s. The histological pattern and frequency however seems to have some slight variation depending on the region and the identified aetiological risk factors.Aims and Objectives: The aim of this study was to determine the pattern of head and neck tumours seen in the region and the commonest malignancies in the cohort. By comparing the relative prevalence of the lesions with other centers in the country and international published literature we hope to make a case for proper tumour registry and move for nation-wide studies.Materials and Methods: The authors reviewed the histopathological data of the tumor registry at the University of Calabar Teaching Hospital, a major referral Center in South-Eastern Nigeria between 2005 and 2012. All cases of head and Neck tumours with histological diagnosis were included for analysis, their demographic data were obtained and analyzed using SPSSv16.Results: Two hundred and twenty-five specimens from the head and neck region were analyzed during this 6 year period giving an average of 34 cases per year. The Male: Female ratio was 1.2:1.The age range was from 2 years to 76 years with overall mean of 32.7 years. One hundred and forty-five cases (63.3%) were benign while 84 malignant cases (36.7%) were recorded for the study period. The average number of new malignant cases seen was 14 per year. Malignancies were commoner in those less than 50 years of age and were mostly those of epithelial origin.Conclusion: Variations in the regional demographics of head and neck tumors in the country could be accounted for by the differences in data collection methods and certain aetiological factors that may be unique to those regions. A proper tumor registry in each region, harmonized with a national cancer registry may resolve some of these discrepancies.Asian Journal of Medical Sciences Vol. 7(3) 2016 123-126

Non-hematological tumors of head and neck region in the pediatric age group in a tertiary care cancer center

2011 ◽  
Vol 27 (9) ◽  
pp. 919-923 ◽  
Author(s):  
Kunal Das ◽  
Sandeep Jain ◽  
Akanksha Chichra ◽  
Himesh Gupta ◽  
Gauri Kapoor
Keyword(s):  
Head And Neck ◽  
Tertiary Care ◽  
Neck Region ◽  
Cancer Center ◽  
Age Group ◽  
Pediatric Age ◽  
Head And Neck Region ◽  
Pediatric Age Group ◽  
Hematological Tumors

scholarly journals Seven Unique Cases of Chondroid Syringomas Reported in KVG Medical College and Hospital

2011 ◽  
Vol 3 (2) ◽  
pp. 102-104 ◽  
Author(s):  
Sudhir Naik ◽  
Sarika S Naik
Keyword(s):  
Head And Neck ◽  
Clinical Presentation ◽  
Neck Region ◽  
Excisional Biopsy ◽  
Age Group ◽  
Head And Neck Region ◽  
Medical College ◽  
Chondroid Syringoma ◽  
Cutaneous Nodule ◽  
Growing Mass

Abstract Chondroid syringoma is a rare, benign, skin appendageal tumor. Because of the unremarkable clinical presentation of this rare tumor, the diagnosis is made on microscopic examination. The usual presentation is of an asymptomatic, slowly growing mass, typically located in the head and neck region. We present seven cases of chondroid syringomas located over the head and neck region of seven patients in the age group between 32 and 56 years. In the evaluation of a small cutaneous nodule in the head and neck region, chondroid syringoma should also be considered in the differential diagnosis. For such a lesion, excisional biopsy without destroying the esthetic and functional structures is the preferred diagnostic as well as therapeutic approach.

scholarly journals Clinicopathological Profile of Rhabdomyosarcoma in Children

2012 ◽  
Vol 30 (3) ◽  
pp. 132-136
Author(s):  
Umme Habiba Begum ◽  
Afiqul Islam
Keyword(s):  
Head And Neck ◽  
Neck Region ◽  
Mass Lesion ◽  
Female Ratio ◽  
Head And Neck Region ◽  
Clinicopathological Profile ◽  
Common Clinical Presentation ◽  
The Common ◽  
Medical University ◽  
Male To Female

Objectives: To describe the clinical profile as well as  histopathological sub-types of Rhabdomyosarcoma in  children.Methods: A hospital base prospective observational study  was conducted among 20 diagnosed cases of  Rhabdomyosarcoma in children, those attending in  Hemato-Oncology department of Bangabandhu Sheikh  Mujib Medical University (BSMMU), Dhaka in the period  between January to December 2009.Results: The peak incidence of Rhabdomyosarcoma was  in 1-5 years of age group (n=9, 45%) with mean age 6.83  years with male to female ratio 5.66:1. The common sites  of primary tumor was in head and neck region (40%, n=08),  followed by genito-urinary tract, 30% (n=06), extremities  20% (n=04), trunk 10% (n=02). The most common clinical  presentation was mass lesion 100% (n=20), followed by local  pain 25% (n=05), urinary obstructions 15% (n=03)  dysphagia, chronic otorrhea, dysuria, haematuria, and  proptoses were 10% each (n=02, each); The histological  sub-types were Embryonal 60% (n=12), alveolar 30% (n=6),  and Botryoid 10% (n=02); Of Embryonal variety in head  and neck region 58.33% (n=7), and Genito-urinary sites  41.67% (n=5); of Alveolar variety in trunk 66.67% (n=4),  and in extremities33.33% (n=2), of Botryoid sub-type  frequency was equal in head - neck region and genitourinary  site 50% each (n=1).Conclusion: Children with Rhabdomyosarcoma presented mostly in 1 to 5 years of age, with mass lesion (100%),  predominantly in head and neck region (40%) and the  commonest histological sub-type was Embryonal variety  (60%). DOI: http://dx.doi.org/10.3329/jbcps.v30i3.12461 J Bangladesh Coll Phys Surg 2012; 30: 132-136

scholarly journals Clinicopathological profile of fungal rhinosinusitis

2012 ◽  
Vol 18 (1) ◽  
pp. 48-54
Author(s):  
Fazal-I Wahid ◽  
Adil Khan ◽  
Iftikhar Ahmad Khan
Keyword(s):  
Middle Age ◽  
Tertiary Care ◽  
Neck Surgery ◽  
Age Group ◽  
Female Ratio ◽  
Fungal Rhinosinusitis ◽  
Male Female Ratio ◽  
Clinicopathological Profile ◽  
Aspergillus Sp ◽  
Age Range

Objective: To determine the clinicopathological features of fungal rhinosinusits at a tertiary care hospital.Material and Methods: This study was conducted at the Department of ENT, Head and Neck surgery, PGMI/ LRH Peshawar. This was a four years prospective study from January 2007 to December 2011. All fifty five patients were evaluated thoroughly in terms of history, examination and investigation. Biopsy of nasal mass was performed and biopsy specimens were studied by same histopathologist. After diagnosing the patient as a case of fungal rhinosinusitis surgical procedure was performed according the extent of disease. The data was analyzed using SPSS version 17.Results: These patients were in age range from 11- 66 years with mean age of 37.74 + S.D 16.46 years. They constitute 34 male and 21 female with male: female ratio was 1.6:1. Majority of patients (41.8%) belonged to middle age group. Most of the patients (60%) had lower socioeconomic status and mainly they were from rural area (74.54%) with only 30.9% literacy level. The commonest symptoms of these patients were nasal stuffiness (85.45%). Noninvasive fungal rhinosinusits was on top (87.27%). Aspergillus sp was the common fungal isolates (12.72%).Conclusion: Fungal rhinosinusitis is commonly affecting middle age group people. Allergic fungal rhinosinusitis is the most common entity of fungal rhinosinusitis and Aspergillus is the commonest pathogen. DOI: http://dx.doi.org/10.3329/bjo.v18i1.10414  Bangladesh J Otorhinolaryngol 2012; 18(1): 48-54

scholarly journals Diagnostic dilemma in cheek lesions in the paediatric age group: thinking beyond the expected

2021 ◽  
Vol 7 (4) ◽  
pp. 687
Author(s):  
Anagha R. Joshi ◽  
Ashwini Sankhe ◽  
Soniya H. Patankar ◽  
Mrinalini M. Rahatgaonkar
Keyword(s):  
Head And Neck ◽  
Neck Region ◽  
Malignant Tumour ◽  
Treatment Modalities ◽  
Age Group ◽  
Common Site ◽  
Diagnostic Dilemma ◽  
Head And Neck Region ◽  
Paediatric Age ◽  
Group Thinking

<p class="abstract">Rhabdomyosarcoma (RMS), a tumour of skeletal muscle origin, is the most common soft tissue sarcoma encountered in childhood. The head and neck region is the most common site of occurrence of RMS. RMS is a highly malignant tumour with extensive local invasions and early haemorrhagic and lymphatic dissemination. Despite the advances in treatment modalities, with aggressive approaches incorporating surgery, combination chemotherapy, and radiation therapy, the outcome for children with extensive, recurrent or metastatic disease remains poor. RMS in the head and neck region can be misdiagnosed as an infective or inflammatory swelling, thereby delaying the treatment. Here, we report a case of oral RMS in a 10-year-old child and highlight the need to include sinister pathologies like RMS in the differential diagnosis when dealing with cheek swellings in the paediatric age group.</p><p class="abstract"> </p>

Sign in / Sign up

Export Citation Format

Share Document