scholarly journals Tulasi a magical herb and a boon for management of oral submucous fibrosis: a clinical study

2017 ◽  
Vol 5 (11) ◽  
pp. 4719 ◽  
Author(s):  
G. Madhulatha ◽  
N. Vijayalaxmi ◽  
T. Harshavardhan
Keyword(s):  
Oral Submucous Fibrosis ◽  
Mouth Opening ◽  
Modern Medicine ◽  
Burning Sensation ◽  
Rank Test ◽  
P Value ◽  
Signed Rank ◽  
Signed Rank Test ◽  
Submucous Fibrosis

Background: Plants are a good source of drugs in traditional and modern medicine. One among these plants is “tulasi” The queen of herbs” which is used in ayurveda for its diverse properties like antioxidant, analgesic, anti-inflammatory, antidiabetic, and others. It belongs to labiate family and is the most sacred and valued in traditional culture of India. AIMS of the study was to evaluate the efficacy of Tulasi in the treatment of OSMF.Methods: The study included 20 individuals, females and males of age group 20-50yrs who visited the outpatient department who were diagnosed clinically as having OSMF, categorized according to pindborg’s classification. Patients were asked to apply 500mg of Tulasi medicine paste (Tulasi powder mixed with glycerine) twice daily for 1month and were recalled for follow up every week for 1month. All the clinical parameters - mouth opening, burning sensation, pain with the lesion and others were evaluated and recorded in specially designed proforma.Results: Friedman test and wilcoxon signed rank test was used for statistical evaluation. Significant improvement with P value <0.05 was noticed in burning sensation, mouth opening and pain associated with the lesion.Conclusions: The study concludes that Tulasi can be used as a main treatment modality in the management of patients with OSMF.

scholarly journals Effectiveness of Pentoxifylline Therapy for Management of Oral Submucous Fibrosis

2022 ◽  
Vol 19 (1) ◽  
pp. 51-54
Author(s):  
Dwarika Prasad Bajgai ◽  
Bela Agrawal ◽  
Abadhesh Yadav
Keyword(s):  
Oral Submucous Fibrosis ◽  
Mouth Opening ◽  
Burning Sensation ◽  
Oral Disease ◽  
Medical College ◽  
Adjacent Structures ◽  
Group A ◽  
Submucous Fibrosis ◽  
Group B

Introduction: Oral submucous fibrosis is a chronic oral disease characterized by progressive buildup of constricting collagen bands in the cheeks and adjacent structures of the mouth due to chewing of areca nut. This can severely restrict mouth opening and tongue movement causing pain and burning sensation in the mouth. Aims: This study evaluates the efficacy of pentoxifylline in the management of oral submucous fibrosis. Methods: A hospital-based study, conducted in the dental outpatient department of Nepalgunj Medical College from October 2019 to September 2020. Forty-nine patients who were diagnosed histopathologically with oral submucous fibrosis were included. The patients were divided into two groups. In group A, patients were given, 200 mg thrice daily for first 30 days, then dose hiked to 400 mg thrice daily for two more months. Group B patients received treatment with multi-vitamin capsules (B-complex one capsule before sleep daily) for three months. All patients were followed up for six months and were assessed for maximum inter-incisor opening, pain on opening of mouth and burning sensation. Results: There was no statistical difference in mouth opening at baseline and first follow up. The mouth opening was significantly more in group A compared to group B from second follow up which persisted till third follow up (p <0.05). Pain and burning sensation significantly reduced in group A compared to group B from 2nd follow up which persisted till 3rd follow up (p <0.05). Few patients had nausea, dyspepsia and vomiting during treatment in group A which resolved within a few days without the need for cessation of the drug. Conclusion: Pentoxifylline can bring about significant clinical improvements in the symptoms of oral submucous fibrosis like mouth opening, pain and burning sensation, thereby improving the quality of life of the affected individuals.

Intraperitoneal Calcitriol in Infants on Peritoneal Dialysis

2007 ◽  
Vol 27 (6) ◽  
pp. 681-686 ◽  
Author(s):  
Francisco J. Cano ◽  
Marta A. Azocar ◽  
Jose Luis Guerrero ◽  
Maria A. Delucchi ◽  
Ana Maria Lillo ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Intraperitoneal Administration ◽  
Oral Route ◽  
Rank Test ◽  
P Value ◽  
Active Vitamin ◽  
Serum Parathyroid Hormone ◽  
Signed Rank ◽  
Signed Rank Test

Background Calcitriol has long been used as the main therapy in renal osteodystrophy, but the efficacy of the oral route is not always as high as expected. Objective To asses the safety and efficacy of intraperitoneal calcitriol in infants undergoing peritoneal dialysis (PD). Patients and Methods PD patients on oral calcitriol therapy, with serum parathyroid hormone (PTH) >1000 pg/mL during the previous 3 months of treatment, were switched to intraperitoneal calcitriol therapy, 1 μg twice per week. Dose was increased to 1 μg three times per week if PTH remained >1000 pg/mL, and was later readjusted. Target PTH was 200 – 300 pg/mL according DOQI guidelines. Statistics: All results are expressed as mean ± SE. The Wilcoxon signed rank test was used to evaluate differences in measurements for each pair of values. The confidence interval for differences between population medians was 96.9%. A p value less than 0.05 was considered significant. Results Six male children, mean age 17 ± 3.86 months, completed a 12-month follow-up. Mean pretreatment PTH was 1654 ± 209 pg/mL. Mean PTH at months 0, 3, 6, 9, and 12 was 1448 ± 439*, 1277 ± 723, 910 ± 704, 582 ± 282*, and 465 ± 224* pg/mL, respectively (*p < 0.05). Twelve hypercalcemic and 10 hyperphosphatemic episodes were successfully treated. Conclusion Infants on PD who fail to respond to oral calcitriol therapy can be safely treated with intraperitoneal administration of active vitamin D.

Role of Laser Biostimulation in Treatment of Oral Submucous Fibrosis: A Clinical Trial

2017 ◽  
Vol 1 (7) ◽  
pp. 22-26 ◽  
Author(s):  
Kesari Singh ◽  
Achint Garg ◽  
Mayank Jain ◽  
Mansimranjit Kaur Uppal
Keyword(s):  
Oral Submucous Fibrosis ◽  
Mouth Opening ◽  
Burning Sensation ◽  
Low Level Laser Therapy ◽  
Entire Study ◽  
Level Laser ◽  
Significant Difference ◽  
Study Population ◽  
Submucous Fibrosis

AIM: To evaluate the efficacy of Low Level Laser Therapy (LLLT) in treatment of Oral Submucous Fibrosis (OSMF).MATERIAL & METHODS: 20 patients with a clinical diagnosis of OSMF were included in the study after informed consents and measurements of mouth opening (mm) and burning sensation (VAS) were made at day 0. Laser biostimulation was performed on right and left cheeks in anterior and posterior bands for 3 cycles of 10 seconds each. They were recalled for follow-up measurements and Laser biostimulation at 3rd, 7th and 15th day. The paired t-test was applied for analysing significant differences, if any, using SPSS version 21.0.RESULTS: In the follow up recordings, generally, there was an increase in mouth opening after LLLT therapy and a significant difference was seen in males(p=.04) as well as the total population(p=0.02). Burning sensation(VAS Scale), on day zero was 5.5±1.20, which was reduced to 3.4±.084 on the 15th day with a significant difference seen in the entire study population(p=0.03).CONCLUSION: Biostimulation by Laser in the treatment of OSMF is a good non-invasive, painless and quick alternative treatment modality for the management of diseases.

Role of KTP-532 laser in management of oral submucous fibrosis

2008 ◽  
Vol 123 (4) ◽  
pp. 418-421 ◽  
Author(s):  
D R Nayak ◽  
S G Mahesh ◽  
D Aggarwal ◽  
P Pavithran ◽  
K Pujary ◽  
...  
Keyword(s):  
Oral Submucous Fibrosis ◽  
Mouth Opening ◽  
Neck Surgery ◽  
Treatment Modalities ◽  
Rank Test ◽  
Tertiary Centre ◽  
Significant Difference ◽  
Signed Rank Test ◽  
Submucous Fibrosis ◽  
Ktp 532 Laser

AbstractIntroduction:Oral submucous fibrosis is a chronic disease characterised by progressive inability to open the mouth. Various treatment modalities are available for its management, but these have largely been ineffective.Materials and methods:Nine cases of oral submucous fibrosis underwent a release procedure using a KTP-532 laser, from March 2005 to January 2006, within the ENT – head and neck surgery department of a tertiary centre.Results:Pre- and post-operative mouth-opening was compared using the Wilcoxon signed rank test, and a significant difference observed (Z = −2.690, p = 0.007). Follow up over an average period of 12 months showed encouraging results.Conclusion:This preliminary study indicated that adequate release of oral submucous fibrosis can be achieved by using a KTP-532 laser release procedure, with minimal morbidity and satisfactory results. These promising results should encourage more widespread use of this technique in the management of this condition.

scholarly journals Peningkatan Resiliensi Perempuan Korban Pelecehan Seksual Melalui Pelatihan Regulasi Emosi

2018 ◽  
Vol 3 (1) ◽  
pp. 117
Author(s):  
Izzaturrohmah Izzaturrohmah ◽  
Nuristighfari Masri Khaerani
Keyword(s):  
Sexual Harassment ◽  
Women Victims ◽  
Emotional Regulation ◽  
Rank Test ◽  
P Value ◽  
Signed Rank ◽  
Wilcoxon Signed Rank Test ◽  
Post Test ◽  
Signed Rank Test

<p class="IABSTRAK"><strong>Abstract: </strong>This research aims to determine the effectiveness of emotional regulation training in increasing resilience in women victims of sexual harassment. Participants in this study were four female victims of sexual harassment. Participants age are 18-30 years and had a moderate to low level resilience score. The research design was one group pre-test post-test. Data collected using resilience scale with Likert model based on resilience aspect from Kumpfer (1999) prepared by the researcher. Emotion regulation training modules were prepared by researcher based on Greenberg theory (2002). Wilcoxon Signed Rank Test technique is used by researcher to test for differences of pre-test, post-test, and post-test2 (follow up) data score. Results of pre-test - post-test analysis showed p value of 0.034 and post-test2 (follow up) with p value of 0.033 (p &lt;0.05). From the result can be concluded that emotional regulation training is effective in increasing resilience in women victims of sexual harassment.</p><strong>Abstrak: </strong>Penelitian ini berujuan untuk mengetahui pengaruh pelatihan regulasi emosi terhadap peningkatan resiliensi pada perempuan korban pelecehan seksual. Partisipan pada penelitian ini merupakan empat perempuan korban pelecehan seksual. Usia partisipan adalah 18-30 tahun dan memiliki skor tingkat resiliensi sedang sampai dengan sedang. Desain penelitian yang digunakan adalah <em>one group pre-test post-test. </em>Pengumpulan data penelitian dilakukan dengan menggunakan skala resiliensi model <em>Likert </em>yang disusun oleh peneliti berdasarkan aspek resiliensi dari Kumpfer (1999). Modul pelatihan regulasi emosi disusun berdasarkan teori Greenberg (2002). Teknik analisis <em>Wilcoxon Signed Rank Test </em>digunakan peneliti untuk menguji perbedaan skor data <em>pre-test, post-test, </em>dan <em>post-test2 </em>(<em>follow up</em>). Hasil analisis <em>pre-test – post-test </em>menunjukkan nilai p sebesar 0.034 dan <em>post-test2 (follow up) </em>dengan nilai p sebesar 0.033 (p&lt;0.05). Hasil penelitian menunjukkan bahwa pelatihan regulasi emosi efektif untuk meningkatkan resiliensi pada perempuan korban pelecehan seksual.

EDUKASI MENGENAI ANEMIA DEFISIENSI BESI BAGI REMAJA PUTRI DENGAN MEDIA LEAFLET

2021 ◽  
pp. 279
Author(s):  
Angelita Afina Arif Putri ◽  
Amirah Salwa ◽  
Utami Wahyuningsih
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Adolescent Girls ◽  
Correct Answer ◽  
Deficiency Anemia ◽  
Rank Test ◽  
P Value ◽  
Signed Rank ◽  
Wilcoxon Signed Rank Test ◽  
Signed Rank Test

One of the nutritional problems that often occurs among adolescents is iron deficiency anemia. Especially for adolescent girls who have a higher risk of anemia than adolescent boys. Based on data from Riskesdas 2018, the prevalence of anemia in adolescents aged 15-24 years is 32%, meaning that there are still anemia problems in Indonesia that have not been resolved. The purpose of this community dedication activity is to provide education about iron deficiency anemia for adolescent girls using leaflet media. The target of this community dedication activity is adolescent girls aged 12-19 years in the JABODETABEK area. The community dedication activity is carried out online through the WhatsApp group due to the COVID-19 pandemic. There are 31 adolescent girls who participated in this community dedication activity. This community dedication activity consists of three stages including pretest, education with leaflets, and posttest. The amount and types of pretest and posttest questions are the same. The amount of questions given is 15 questions. The correct answer is given a score of 10 and the wrong one is given a score of 0. The level of knowledge of adolescent girls is categorized as 3 groups, which is less if the correct answer is <60%, sufficient if the correct answer is 60-80%, and good if the correct answer is >80%. Most of the adolescent girls are in the age range of 17-19 years (54.8%). The results showed that there was an increase in knowledge about iron deficiency anemia in adolescent girls. The results of the Wilcoxon signed rank test showed significantly different pretest and posttest results (p-value = 0.000), so it can be concluded that providing education using leaflets can help increase knowledge of iron deficiency anemia for adolescent girls.Salah satu masalah gizi yang sering terjadi pada kalangan remaja yaitu anemia defisiensi besi. Khususnya bagi remaja putri yang memiliki risiko lebih tinggi mengalami anemia dibandingkan remaja putra. Berdasarkan data Riskesdas 2018, prevalensi anemia pada remaja berusia 15-24 tahun sebesar 32%, artinya masih terdapat permasalahan anemia di Indonesia yang belum teratasi. Tujuan dari pengabdian masyarakat ini adalah untuk memberikan edukasi mengenai anemia defisiensi besi bagi remaja putri dengan media leaflet. Sasaran dari kegiatan pengabdian masyarakat ini adalah remaja putri berusia 12-19 tahun di wilayah JABODETABEK. Kegiatan pengabdian masyarakat dilakukan secara online melalui grup whatsappkarena kondisi pandemi covid-19. Total remaja putri yang mengikuti kegiatan pengabdian masyarakat berjumlah 31 orang. Kegiatan pengabdian masyarakat ini terdiri dari tiga tahapan diantaranya pretest, edukasi dengan leaflet, dan posttest.  Jumlah dan jenis pertanyaan pretest dan posttest sama. Jumlah pertanyaan yang diberikan adalah 15 soal. Jawaban yang benar diberikan nilai 10 dan yang salah diberikan nilai 0. Tingkat pengetahuan remaja putri dikelompokkan menjadi 3 diantaranya kurang jika jawaban yang benar < 60%, cukup jika jawaban yang benar 60-80%, dan baik jika jawaban yang benar > 80%. Sebagian besar remaja putri berada pada rentang usia 17-19 tahun (54,8%). Hasil menunjukkan bahwa terdapat peningkatan pengetahuan mengenai anemia defisiensi besi pada remaja putri. Hasil uji Wilcoxon signed rank test menunjukkan hasil pretest dan posttest yang berbeda nyata (p-value = 0,000), sehingga dapat disimpulkan bahwa pemberian edukasi menggunakan leaflet dapat membantu meningkatkan pengetahuan anemia defisiensi besi bagi remaja putri.

Comparison Of Collagen-Curcumin Blend (Collaper Rtu)With Intralesional Steroid Injections in Oral Submucous Fibrosis a Randomized, Open-Label Interventional Study.

2021 ◽  
Author(s):  
Bharat Kwatra ◽  
Manya Pahwa
Keyword(s):  
Oral Submucous Fibrosis ◽  
Mouth Opening ◽  
Burning Sensation ◽  
Current Therapy ◽  
Intralesional Injection ◽  
Complete Regression ◽  
Open Label ◽  
Tongue Protrusion ◽  
Interincisal Distance ◽  
Submucous Fibrosis

Abstract Introduction: Oral Submucous Fibrosis (OSMF) is a precancerous condition characterized by limited mouth opening, burning sensation, stiffness, and blanching of the oral mucosa induced by areca nut eating. With any of the current therapy regimens, complete regression of the illness has not been accomplished in all patients. Curcumin is a yellow pigment found in curry powder that has antioxidant, anti-inflammatory, and pro-apoptotic properties. As a result, interventional research was conducted to determine the efficacy of Collaper RTu a proprietary collagen-curcumin based product in patients with OSMF.Setting and design: Forty patients with clinically and histologically confirmed Oral Submucous Fibrosis participated in a randomized open label interventional research. Method & materials: For the research, forty patients with clinically and histologically verified Oral Submucous Fibrosis were randomly assigned to one of two groups. The first group was given a weekly intralesional injection of 4 mg Dexamethasone and 1500 I.U Hyaluronidase, whereas the second was given two Collagen-Curcumin pills (Collaper Rtu 60mg Collagen with 100 mg Curcumin) every day for three months. On a weekly basis, the improvement of burning sensation, interincisal distance, and tongue protrusion was assessed.Results: From early to late stages, the burning feeling improved in both groups. Collaper Rtu was found to eliminate the burning feeling. In groups 1 and 2, the mean increase in interincisal distance was 3.13 mm and 1.25 mm, respectively. The interincisal distance improved significantly in both groups by the end of the first month. When compared to group 2, group 1's tongue protrusion recovered faster at the conclusion of the first month. Conclusion: Collaper RTu is useful and effective in lowering the burning feeling in people with early OSMF.

EFEKTIVITAS PEMBERIAN INFUSED WATER KURMA TERHADAP PENINGKATAN KADAR HEMOGLOBIN REMAJA PUTRI KEBIDANAN POLTEKKES MEDAN TAHUN 2020

2021 ◽  
Vol 2 (1) ◽  
pp. 64-69
Author(s):  
HIJRA HIDAYANA ◽  
Suswati Suswati
Keyword(s):  
Red Blood Cells ◽  
Adolescent Girls ◽  
Blood Cells ◽  
The Body ◽  
Rank Test ◽  
Plain Water ◽  
P Value ◽  
Signed Rank ◽  
Wilcoxon Signed Rank Test ◽  
Signed Rank Test

Hemoglobin is the red pigment-protein contained in red blood cells. The function of hemoglobin is to transport oxygen from the lungs and in the bloodstream to be carried to the tissues. Hemoglobin can increase by increasing the intake of iron in the body. One way to increase hemoglobin can be done by giving method Infused Water Dates. Infused water is a drink consisting of plain water with fresh fruit added and soaking or settling together for a certain time. The making of infused water is carried out by soaking for a period of 0 to 12 hours, so that the infused water becomes a liquid medium that carries more nutrients than ordinary water and will be more easily absorbed by cells and distributed throughout the body (Sidauruk, 2018 ). In several studies, it is stated that dates can increase hemoglobin levels in the blood. Where dates contain iron, vitamin A, vitamin C, protein to form red blood cells. With the method, Infused Water the date palm water becomes alkaline so that it can accelerate the absorption process in the body. The purpose of this study was to determine the effectiveness of dates infused water provision to increase hemoglobin levels of midwifery adolescent girls at Medan Health Polytechnic in 2020. This research was quasi-experimental study using the One Group Pretest-Posttest Without Control Design approach. The sample in this study were 20 respondents of midwifery adolescent girls from Medan Health Polytechnic, using the technique of purposive sampling. The statistical test used wa the Wilcoxon Signed Rank Test because the data was not normal. The results of the Wilcoxon Signed Rank Test obtained the value of P-Value = 0.001. So it can be concluded that the date infused water  is effective in increasing hemoglobin levels of midwifery adolescent girls at Medan Health Polytechnic in 2020.   Keywords: Dates Infused Water, Increased Hemoglobin Levels, Girls Adolescent

scholarly journals PERBANDINGAN EFEKTIVITAS CIRCULO MASSAGE DANSPORT MASSAGE DALAM MENGATASI KELELAHAN KERJAKARYAWAN LAKI - LAKI GADJAH MADA MEDICAL CENTER

MEDIKORA ◽  
2015 ◽  
Author(s):  
Kunto Prastowo dan Novita Intan Arovah
Keyword(s):  
Medical Center ◽  
Rank Test ◽  
P Value ◽  
Purposive Sampling ◽  
Signed Rank ◽  
Signed Rank Test

Penelitian ini bertujuan mengetahui perbandingan efektivitas circulo massage dansport massage dalam mengatasi kelelahan kerja karyawan Gadjah Mada Medical Center.Penelitian ini merupakan penelitian pra eksperimen dengan desain treatment bysubjects. Subjek penelitian ini adalah 15 karyawan laki-laki GMC yang direkrut denganteknik purposive sampling. Subjek diberi dua perlakuan yakni circulo massage dan sportmassage dengan selang waktu + 1 minggu. Sebelum dan sesudah perlakuan massagedilakukan pengukuran tingkat kelelahan kerja dengan menggunakan kuisioner kelelahankerja yang telah diujicoba dan dinyatakan valid dan koefisien reliabilitas sebesar 0,779.Teknik analisis data yang digunakan dalam penelitian ini adalah analisis deskriptif,analisis efektivitas (nilai posttest-pretest)/ pretest) dan uji beda dengan menggunakan ujiwilcoxon signed rank test dengan taraf signifikansi 5 %.Hasil penelitian menunjukkan bahwa nilai rata-rata pretest dan posttest kelelahankerja pada perlakuan circulo massage adalah 29 dan 20,53, uji efektivitas menunjukkanpenurunan 29,20 % (p value: 0,0012). Pada penelitian dengan perlakuan sport massagemenunjukkan bahwa nilai rata-rata pretest dan posttest kelelahan kerja adalah 29,9 dan17,5, uji efektivitas menunjukkan penurunan 41,47 % (p value : 0.0006). Perbandinganantara kelelahan kerja pada perlakuan efektivitas circulo massage dan sport massagemenghasilkan p value: 0,0287. Dapat disimpulkan sport massage lebih efektifdibandingkan circulo massage dalam mengatasi kelelahan kerja pada karyawan laki-lakiGadjah Mada Medical Center.Kata kunci : Circulo massage, sport massage, kelelahan kerja

scholarly journals The Effect of Tai Chi Gymnastic on Decreasing Low Back Pain of Elderly Farmers

2019 ◽  
Vol 2 (5) ◽  
pp. 118
Author(s):  
Endang Yuswatiningsih ◽  
Dyah Elvi Meiedietik ◽  
Nining Mustika Ningrum
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Tai Chi ◽  
Rank Test ◽  
P Value ◽  
Low Back ◽  
Signed Rank ◽  
Keywords Low Back Pain ◽  
Wilcoxon Signed Rank Test ◽  
Signed Rank Test

Low back pain is one of health problems that distrub a daily comfort and activities. Low back pain increasing along with the increase of age and bent forward position which was applied in daily working by elderly farmers. The aim of this study was to analyze the effect of tai chi gymnastic on decreasing low back pain of elderly farmers. The research design of this study was one group of pre test-post test design. The population objects in this study were all of elderly farmers with low back pain complaints which were recorder in the elderly medical center, which contained of 32 samples in total and were determined using simple random sampling technique. The independent variable in this study was Tai Chi gymnastic and low back pain of elderly farmers as dependent variable. Verbal descriptor scale was used as the data collection method. This study was using editing, coding, scoring and tabulating as data processing techniques, and Wilcoxon signed rank test on testing the statistics. The result of this study showed the percentages of each low back pain phases, which contained of 41% mild low back pain, 50% moderate low back pain and 9% hard low back pain before tai chi gymnastics. Besides, the percentages of low back pain phases after tai chi gymnastic were 69% for mild low back pain, 31% moderate low back pain and 0% hard low back pain. The result of Wilcoxon signed rank test showed that the p-value = 0.001 < 0.05, so that H0 was rejected. The conclusion there was an effect of Tai chi gymnastic on decreasing low back pain of elderly farmers. Keywords: low back pain; elderly farmers; Tai chi gymnastic

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