Intraperitoneal Calcitriol in Infants on Peritoneal Dialysis

2007 ◽  
Vol 27 (6) ◽  
pp. 681-686 ◽  
Author(s):  
Francisco J. Cano ◽  
Marta A. Azocar ◽  
Jose Luis Guerrero ◽  
Maria A. Delucchi ◽  
Ana Maria Lillo ◽  
...  

Background Calcitriol has long been used as the main therapy in renal osteodystrophy, but the efficacy of the oral route is not always as high as expected. Objective To asses the safety and efficacy of intraperitoneal calcitriol in infants undergoing peritoneal dialysis (PD). Patients and Methods PD patients on oral calcitriol therapy, with serum parathyroid hormone (PTH) >1000 pg/mL during the previous 3 months of treatment, were switched to intraperitoneal calcitriol therapy, 1 μg twice per week. Dose was increased to 1 μg three times per week if PTH remained >1000 pg/mL, and was later readjusted. Target PTH was 200 – 300 pg/mL according DOQI guidelines. Statistics: All results are expressed as mean ± SE. The Wilcoxon signed rank test was used to evaluate differences in measurements for each pair of values. The confidence interval for differences between population medians was 96.9%. A p value less than 0.05 was considered significant. Results Six male children, mean age 17 ± 3.86 months, completed a 12-month follow-up. Mean pretreatment PTH was 1654 ± 209 pg/mL. Mean PTH at months 0, 3, 6, 9, and 12 was 1448 ± 439*, 1277 ± 723, 910 ± 704, 582 ± 282*, and 465 ± 224* pg/mL, respectively (*p < 0.05). Twelve hypercalcemic and 10 hyperphosphatemic episodes were successfully treated. Conclusion Infants on PD who fail to respond to oral calcitriol therapy can be safely treated with intraperitoneal administration of active vitamin D.

Author(s):  
G. Madhulatha ◽  
N. Vijayalaxmi ◽  
T. Harshavardhan

Background: Plants are a good source of drugs in traditional and modern medicine. One among these plants is “tulasi” The queen of herbs” which is used in ayurveda for its diverse properties like antioxidant, analgesic, anti-inflammatory, antidiabetic, and others. It belongs to labiate family and is the most sacred and valued in traditional culture of India. AIMS of the study was to evaluate the efficacy of Tulasi in the treatment of OSMF.Methods: The study included 20 individuals, females and males of age group 20-50yrs who visited the outpatient department who were diagnosed clinically as having OSMF, categorized according to pindborg’s classification. Patients were asked to apply 500mg of Tulasi medicine paste (Tulasi powder mixed with glycerine) twice daily for 1month and were recalled for follow up every week for 1month. All the clinical parameters - mouth opening, burning sensation, pain with the lesion and others were evaluated and recorded in specially designed proforma.Results: Friedman test and wilcoxon signed rank test was used for statistical evaluation. Significant improvement with P value <0.05 was noticed in burning sensation, mouth opening and pain associated with the lesion.Conclusions: The study concludes that Tulasi can be used as a main treatment modality in the management of patients with OSMF.


2018 ◽  
Vol 3 (1) ◽  
pp. 117
Author(s):  
Izzaturrohmah Izzaturrohmah ◽  
Nuristighfari Masri Khaerani

<p class="IABSTRAK"><strong>Abstract: </strong>This research aims to determine the effectiveness of emotional regulation training in increasing resilience in women victims of sexual harassment. Participants in this study were four female victims of sexual harassment. Participants age are 18-30 years and had a moderate to low level resilience score. The research design was one group pre-test post-test. Data collected using resilience scale with Likert model based on resilience aspect from Kumpfer (1999) prepared by the researcher. Emotion regulation training modules were prepared by researcher based on Greenberg theory (2002). Wilcoxon Signed Rank Test technique is used by researcher to test for differences of pre-test, post-test, and post-test2 (follow up) data score. Results of pre-test - post-test analysis showed p value of 0.034 and post-test2 (follow up) with p value of 0.033 (p &lt;0.05). From the result can be concluded that emotional regulation training is effective in increasing resilience in women victims of sexual harassment.</p><strong>Abstrak: </strong>Penelitian ini berujuan untuk mengetahui pengaruh pelatihan regulasi emosi terhadap peningkatan resiliensi pada perempuan korban pelecehan seksual. Partisipan pada penelitian ini merupakan empat perempuan korban pelecehan seksual. Usia partisipan adalah 18-30 tahun dan memiliki skor tingkat resiliensi sedang sampai dengan sedang. Desain penelitian yang digunakan adalah <em>one group pre-test post-test. </em>Pengumpulan data penelitian dilakukan dengan menggunakan skala resiliensi model <em>Likert </em>yang disusun oleh peneliti berdasarkan aspek resiliensi dari Kumpfer (1999). Modul pelatihan regulasi emosi disusun berdasarkan teori Greenberg (2002). Teknik analisis <em>Wilcoxon Signed Rank Test </em>digunakan peneliti untuk menguji perbedaan skor data <em>pre-test, post-test, </em>dan <em>post-test2 </em>(<em>follow up</em>). Hasil analisis <em>pre-test – post-test </em>menunjukkan nilai p sebesar 0.034 dan <em>post-test2 (follow up) </em>dengan nilai p sebesar 0.033 (p&lt;0.05). Hasil penelitian menunjukkan bahwa pelatihan regulasi emosi efektif untuk meningkatkan resiliensi pada perempuan korban pelecehan seksual.


2021 ◽  
pp. 279
Author(s):  
Angelita Afina Arif Putri ◽  
Amirah Salwa ◽  
Utami Wahyuningsih

One of the nutritional problems that often occurs among adolescents is iron deficiency anemia. Especially for adolescent girls who have a higher risk of anemia than adolescent boys. Based on data from Riskesdas 2018, the prevalence of anemia in adolescents aged 15-24 years is 32%, meaning that there are still anemia problems in Indonesia that have not been resolved. The purpose of this community dedication activity is to provide education about iron deficiency anemia for adolescent girls using leaflet media. The target of this community dedication activity is adolescent girls aged 12-19 years in the JABODETABEK area. The community dedication activity is carried out online through the WhatsApp group due to the COVID-19 pandemic. There are 31 adolescent girls who participated in this community dedication activity. This community dedication activity consists of three stages including pretest, education with leaflets, and posttest. The amount and types of pretest and posttest questions are the same. The amount of questions given is 15 questions. The correct answer is given a score of 10 and the wrong one is given a score of 0. The level of knowledge of adolescent girls is categorized as 3 groups, which is less if the correct answer is <60%, sufficient if the correct answer is 60-80%, and good if the correct answer is >80%. Most of the adolescent girls are in the age range of 17-19 years (54.8%). The results showed that there was an increase in knowledge about iron deficiency anemia in adolescent girls. The results of the Wilcoxon signed rank test showed significantly different pretest and posttest results (p-value = 0.000), so it can be concluded that providing education using leaflets can help increase knowledge of iron deficiency anemia for adolescent girls.Salah satu masalah gizi yang sering terjadi pada kalangan remaja yaitu anemia defisiensi besi. Khususnya bagi remaja putri yang memiliki risiko lebih tinggi mengalami anemia dibandingkan remaja putra. Berdasarkan data Riskesdas 2018, prevalensi anemia pada remaja berusia 15-24 tahun sebesar 32%, artinya masih terdapat permasalahan anemia di Indonesia yang belum teratasi. Tujuan dari pengabdian masyarakat ini adalah untuk memberikan edukasi mengenai anemia defisiensi besi bagi remaja putri dengan media leaflet. Sasaran dari kegiatan pengabdian masyarakat ini adalah remaja putri berusia 12-19 tahun di wilayah JABODETABEK. Kegiatan pengabdian masyarakat dilakukan secara online melalui grup whatsappkarena kondisi pandemi covid-19. Total remaja putri yang mengikuti kegiatan pengabdian masyarakat berjumlah 31 orang. Kegiatan pengabdian masyarakat ini terdiri dari tiga tahapan diantaranya pretest, edukasi dengan leaflet, dan posttest.  Jumlah dan jenis pertanyaan pretest dan posttest sama. Jumlah pertanyaan yang diberikan adalah 15 soal. Jawaban yang benar diberikan nilai 10 dan yang salah diberikan nilai 0. Tingkat pengetahuan remaja putri dikelompokkan menjadi 3 diantaranya kurang jika jawaban yang benar < 60%, cukup jika jawaban yang benar 60-80%, dan baik jika jawaban yang benar > 80%. Sebagian besar remaja putri berada pada rentang usia 17-19 tahun (54,8%). Hasil menunjukkan bahwa terdapat peningkatan pengetahuan mengenai anemia defisiensi besi pada remaja putri. Hasil uji Wilcoxon signed rank test menunjukkan hasil pretest dan posttest yang berbeda nyata (p-value = 0,000), sehingga dapat disimpulkan bahwa pemberian edukasi menggunakan leaflet dapat membantu meningkatkan pengetahuan anemia defisiensi besi bagi remaja putri.


2021 ◽  
Vol 2 (1) ◽  
pp. 64-69
Author(s):  
HIJRA HIDAYANA ◽  
Suswati Suswati

Hemoglobin is the red pigment-protein contained in red blood cells. The function of hemoglobin is to transport oxygen from the lungs and in the bloodstream to be carried to the tissues. Hemoglobin can increase by increasing the intake of iron in the body. One way to increase hemoglobin can be done by giving method Infused Water Dates. Infused water is a drink consisting of plain water with fresh fruit added and soaking or settling together for a certain time. The making of infused water is carried out by soaking for a period of 0 to 12 hours, so that the infused water becomes a liquid medium that carries more nutrients than ordinary water and will be more easily absorbed by cells and distributed throughout the body (Sidauruk, 2018 ). In several studies, it is stated that dates can increase hemoglobin levels in the blood. Where dates contain iron, vitamin A, vitamin C, protein to form red blood cells. With the method, Infused Water the date palm water becomes alkaline so that it can accelerate the absorption process in the body. The purpose of this study was to determine the effectiveness of dates infused water provision to increase hemoglobin levels of midwifery adolescent girls at Medan Health Polytechnic in 2020. This research was quasi-experimental study using the One Group Pretest-Posttest Without Control Design approach. The sample in this study were 20 respondents of midwifery adolescent girls from Medan Health Polytechnic, using the technique of purposive sampling. The statistical test used wa the Wilcoxon Signed Rank Test because the data was not normal. The results of the Wilcoxon Signed Rank Test obtained the value of P-Value = 0.001. So it can be concluded that the date infused water  is effective in increasing hemoglobin levels of midwifery adolescent girls at Medan Health Polytechnic in 2020.   Keywords: Dates Infused Water, Increased Hemoglobin Levels, Girls Adolescent


MEDIKORA ◽  
2015 ◽  
Author(s):  
Kunto Prastowo dan Novita Intan Arovah

Penelitian ini bertujuan mengetahui perbandingan efektivitas circulo massage dansport massage dalam mengatasi kelelahan kerja karyawan Gadjah Mada Medical Center.Penelitian ini merupakan penelitian pra eksperimen dengan desain treatment bysubjects. Subjek penelitian ini adalah 15 karyawan laki-laki GMC yang direkrut denganteknik purposive sampling. Subjek diberi dua perlakuan yakni circulo massage dan sportmassage dengan selang waktu + 1 minggu. Sebelum dan sesudah perlakuan massagedilakukan pengukuran tingkat kelelahan kerja dengan menggunakan kuisioner kelelahankerja yang telah diujicoba dan dinyatakan valid dan koefisien reliabilitas sebesar 0,779.Teknik analisis data yang digunakan dalam penelitian ini adalah analisis deskriptif,analisis efektivitas (nilai posttest-pretest)/ pretest) dan uji beda dengan menggunakan ujiwilcoxon signed rank test dengan taraf signifikansi 5 %.Hasil penelitian menunjukkan bahwa nilai rata-rata pretest dan posttest kelelahankerja pada perlakuan circulo massage adalah 29 dan 20,53, uji efektivitas menunjukkanpenurunan 29,20 % (p value: 0,0012). Pada penelitian dengan perlakuan sport massagemenunjukkan bahwa nilai rata-rata pretest dan posttest kelelahan kerja adalah 29,9 dan17,5, uji efektivitas menunjukkan penurunan 41,47 % (p value : 0.0006). Perbandinganantara kelelahan kerja pada perlakuan efektivitas circulo massage dan sport massagemenghasilkan p value: 0,0287. Dapat disimpulkan sport massage lebih efektifdibandingkan circulo massage dalam mengatasi kelelahan kerja pada karyawan laki-lakiGadjah Mada Medical Center.Kata kunci : Circulo massage, sport massage, kelelahan kerja


2019 ◽  
Vol 2 (5) ◽  
pp. 118
Author(s):  
Endang Yuswatiningsih ◽  
Dyah Elvi Meiedietik ◽  
Nining Mustika Ningrum

Low back pain is one of health problems that distrub a daily comfort and activities. Low back pain increasing along with the increase of age and bent forward position which was applied in daily working by elderly farmers. The aim of this study was to analyze the effect of tai chi gymnastic on decreasing low back pain of elderly farmers. The research design of this study was one group of pre test-post test design. The population objects in this study were all of elderly farmers with low back pain complaints which were recorder in the elderly medical center, which contained of 32 samples in total and were determined using simple random sampling technique. The independent variable in this study was Tai Chi gymnastic and low back pain of elderly farmers as dependent variable. Verbal descriptor scale was used as the data collection method. This study was using editing, coding, scoring and tabulating as data processing techniques, and Wilcoxon signed rank test on testing the statistics. The result of this study showed the percentages of each low back pain phases, which contained of 41% mild low back pain, 50% moderate low back pain and 9% hard low back pain before tai chi gymnastics. Besides, the percentages of low back pain phases after tai chi gymnastic were 69% for mild low back pain, 31% moderate low back pain and 0% hard low back pain. The result of Wilcoxon signed rank test showed that the p-value = 0.001 < 0.05, so that H0 was rejected. The conclusion there was an effect of Tai chi gymnastic on decreasing low back pain of elderly farmers. Keywords: low back pain; elderly farmers; Tai chi gymnastic


Author(s):  
Dr Subrat Panda ◽  
Dr Ananya Das ◽  
Dr Surajit Ray Baruah ◽  
Lina Baruah

Introduction: The interactive teaching system is one such tool which aims at improving the conventional lecture. In this study we had compared three types of interactive teaching viz., flipped class room, MCQ (Multiple Choice Question) based interactive teaching and confusion technique by kircpatrics level 1 evaluation. Methodology: It was an academic study conducted for a period of 1year for final year M.B.B.S students’ batch of 50 in Obstetrics and Gynaecology department of NEIGRIHMS from March 2018 to March 2019. Out of a total of 12 topics selected for interactive teaching technique, 4 topics were taught in flipped classroom technique, another 4 taught with putting MCQ in the class and remaining 4 topics were taught using confusion technique. Immediate feedback was obtained from students using likert chart. All the data were collected and analysed by Wilcoxon Signed rank test by using SPS Software 22. Observation: Flipped classroom technique of teaching was found preferable to MCQ technique (p value<0.01). Also flipped class room technique was preferred by student to confusion technique (p value<0.01). On comparision between MCQ and Confusion technique, MCQ was preferred by the students (p value <0.01). Conclusion: Interactive techniques and strategies make the students actively involved in the learning process, retaining more information and hence leaving them satisfied. In our study, flipped classroom method was the most preferred method by the students as a modality of interactive teaching when compared to MCQ based teaching and Confusion technique.


Author(s):  
Iin Setiawati

                        During pregnancy, the need for increasedcalcium intake. Adequate calcium intake can reducethe risk of preeclampsia. the survey results ofpreliminary studies in Polindes Asemjaran Banyuates over the pastthree months, Found that three pregnant womendetected preeclampsia from a total of 57 pregnantwomen (5.26%). The purpose of the study to analyzethe effectiveness of calcium in pregnant women topreventing preeclampsia in the working area ofPolindes Asemjaran Banyuates. The research design used was QuasiEksperimen with Non Equivalent Control Groupapproach. The independent variable is CalciumSupplementation and dependence is the Occurrenceof Preeclampsi on Trimester 2 Pregnant Woman. Thesample of this study is trimester 2 pregnant womenwho are at risk of experiencing preeclampsia thatmeet the criteria. The instrument was used theobservation sheet, and analyzed using ParametricTest if qualified and non-parameteric test if notqualified with a 0.05. The result of statistical test in both dose group500 mg and 1000 mg with Paired T-Test wasobtained p value (0,941)> α (0,05) in 500 mg dosegroup and Wilcoxon Signed Rank Test result p value(0,105) > a ( 0.05) at a dose of 1000 mg the meanings H1 and H2 are rejected, there is no differencebefore and after given calcium supplement dose 500mg or 1000 mg to prevent preeclampsi. While in theposttest test with Mann Whitney Test in both groupsobtained results p Value (0.105)> α (0.05), it can beconcluded that supplementation of calcium dose 500mg and 1000 mg not effective to preventpreeclampsia. Calcium supplementation of 1000 mg and 500mg doses has not been proven statistically effectiven preventing preeclampsia. Further research isrecommended to increase the number of samples, sothat the research results will be visible and can begeneralized to all pregnant women.  


Author(s):  
Debanjali Sinha ◽  
Sumantro Mondal ◽  
Arijit Nag ◽  
Debasish Lahiri ◽  
Alakendu Ghosh

Background: The objective of the present study was to monitor the disease activity of Takayasu arteritis clinically by the Indian Takayasu Activity Score 2010 (ITAS) and ultra sonographically by Colour Doppler Ultrasound-Kolkata (CDUS-K) Score after 12months of treatment with methotrexate and steroid, and to find the correlation between these two scores.Methods: Around 25 Angiographically proven Takayasu arteritis patients were treated with Methotrexate (15mg weekly) and Steroids (1mg/kg/day for 6weeks and then tapered) for 12months. Wilcoxon matched pair signed rank test was done to assess the change in ITAS 2010 with treatment. A correlation study was done between ITAS 2010 and change in CDUS-K scores at the end of 12months.Results: By Wilcoxon’s matched pair signed rank test, a non-significant change of ITAS 2010 (p=0.066) was observed at the end of 12months, which means that the treatment helps to control the disease progression by preventing a significant increase in ITAS 2010. Strong correlation (correlation coefficient of 0.878, 95% CI = 0.602 to 1.000) was found between the ITAS 2010 and change in CDUS-K scores at 12months follow up.Conclusions: The combination of Methotrexate and steroids helps to control the disease progression in Takayasu arteritis. Colour doppler ultrasonography may serve as a reliable and safe surrogate disease activity measure at follow up, as it avoids the radioactivity exposure and invasiveness of angiography.


Author(s):  
Chilyatiz Zahroh ◽  
Siti Nurjanah ◽  
Ninin Khumairoh Siti Widyarti

Hypertension is a significant risk factor for heart disease and stroke. This study was conducted to determine the effect of abdominal breathing on blood pressure in a hypertensive patient using the non-pharmacological treatment. This study used a pre-experimental method, which comprises of the one-group pre-test/post-test design. A total of 39 hypertensive respondents taken from a population in Wonokromo, Surabaya were chosen by using simple random sampling technique. Data was analyzed by Wilcoxon Signed-Rank Test, with an assigned significance level of ɑ=0.05. The results of this study showed that before abdominal breathing, the systolic blood pressure was 146.41 mmHg, whereas the diastolic blood pressure was 117.43 mmHg. After performing abdominal relaxation, it was 135.64 mmHg and 87.95 mmHg, respectively. Moreover, the results of the Wilcoxon Signed-Rank Test showed a p-value of 0.000, illustrating that the results of blood pressure measurement were different before and after conducting the abdominal breathing. Therefore, abdominal breathing is suspected of having the ability to decrease the blood pressure.


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