scholarly journals Prevalence of anemia in type II diabetes mellitus patients

2019 ◽  
Vol 7 (9) ◽  
pp. 3536
Author(s):  
Sreenivas Reddy ◽  
Molugu Divya Reddy
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
General Medicine ◽  
Type Ii Diabetes Mellitus ◽  
Diabetic Patients ◽  
Patients With Diabetes ◽  
One Year ◽  
Prevalence Of Anemia

Background: Anemia is a common haematological finding in diabetic patients. The prevalence of anemia in the patients with diabetes is two or three times higher than in patients with comparable renal impairment and iron stores in the general population. As India is foreseen a diabetic capital of the world, it becomes imperative to recognize co-morbidities such as anemia at the earliest. The aim of this study was to determine the prevalence of anemia among patients with type 2 diabetes. Author conducted a prospective analysis of 100 diabetic patients visiting the outpatient clinic in our institution. Duration of study is One Year (November 2016 - December 2017). Study perform at Om Sai Hospitals, Balapur, Hyderabad, Telangana, India. A 100 patients suffering from type 2 Diabetes Mellitus, attending Outpatient Department of General Medicine, were included in the study.Methods: All the patients were subjected to detailed history, through clinical examination and investigation. Patients’ blood samples were analyzed for Glycated hemoglobin (HbA1C) values and hemoglobin (Hb) levels. The prevalence of anemia was then determined defining anemia by an Hb level <13.0 g/dL for men and <12.0 g/dL for women.Results: The prevalence of anemia in this study population was found to be 43%. The prevalence of anemia is significantly greater in diabetic females than in diabetic males and in poorly controlled diabetics than those with glycemic status under control.Conclusions: We conclude that anemia is a prevalent finding in patients with type 2 diabetes mellitus and represents significant unrecognised burden.

Prevalence of Toenail Onychomycosis in Patients with Type 2 Diabetes Mellitus and Evaluation of Risk Factors

2011 ◽  
Vol 101 (1) ◽  
pp. 49-54 ◽  
Author(s):  
Aynur Gulcan ◽  
Erim Gulcan ◽  
Sukru Oksuz ◽  
Idris Sahin ◽  
Demet Kaya
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Fasting Blood Glucose ◽  
Diabetic Patients ◽  
Essential Components ◽  
Patients With Diabetes ◽  
Epidemiologic Risk

Background: We sought to determine the frequency of toenail onychomycosis in diabetic patients, to identify the causative agents, and to evaluate the epidemiologic risk factors. Methods: Data regarding patients’ diabetic characteristics were recorded by the attending internal medicine clinician. Clinical examinations of patients’ toenails were performed by a dermatologist, and specimens were collected from the nails to establish the onycomycotic abnormality. All of the specimens were analyzed by direct microscopy and culture. Results: Of 321 patients with type 2 diabetes mellitus, clinical onychomycosis was diagnosed in 162; 41 of those diagnoses were confirmed mycologically. Of the isolated fungi, 23 were yeasts and 18 were dermatophytes. Significant correlations were found between the frequency of onychomycosis and retinopathy, neuropathy, obesity, family history, and duration of diabetes. However, no correlation was found with sex, age, educational level, occupation, area of residence, levels of hemoglobin A1c and fasting blood glucose, and nephropathy. The most frequently isolated agents from clinical specimens were yeasts. Conclusions: Long-term control of glycemia to prevent chronic complications and obesity and to promote education about the importance of foot and nail care should be essential components in preventing onychomycosis and its potential complications, such as secondary foot lesions, in patients with diabetes mellitus. (J Am Podiatr Med Assoc 101(1): 49–54, 2011)

scholarly journals Study on Thyroid Dysfunction in Patients with Type-2 Diabetes

2020 ◽  
Vol 7 (52) ◽  
pp. 3142-3147
Author(s):  
Senthil Chander ◽  
Kalpana Dev Venkatesan ◽  
Christina Mary Paul
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Subclinical Hypothyroidism ◽  
Thyroid Dysfunction ◽  
General Medicine ◽  
Diabetic Patients ◽  
Endocrine Disorders ◽  
Cross Sectional ◽  
Patients With Diabetes

BACKGROUND Diabetes mellitus is one of the leading endocrine disorders worldwide. Thyroid dysfunction is a common endocrine disorder affecting the general population next to diabetes. The objective of this study was to determine the prevalence of thyroid dysfunction among patients with Type 2 diabetes. METHODS This analytical cross sectional study was conducted from June 2019 to Dec 2019. One hundred and fifty type–2 diabetes patients who attended the outpatient clinic of General Medicine Department, ACS Medical College and Hospital were included in the study. A detailed history and examination was done after getting informed consent. Blood samples were collected and sent to the laboratory for the evaluation of thyroid profile. RESULTS Thyroid dysfunction was found in 27 % of the patients with diabetes. Subclinical hypothyroidism was the most common thyroid dysfunction reported (14.7 %) followed by clinical hypothyroidism (10 %), subclinical hyperthyroidism (2 %) and clinical hyperthyroidism (0.6 %). CONCLUSIONS Thyroid dysfunction is common in patients with type-2 diabetes. A substantial proportion of the diabetic patients with thyroid dysfunction have subclinical hypothyroidism. Unidentified thyroid dysfunction could negatively impact diabetes and its complications. Therefore, early and routine screening of thyroid is recommended in all patients with diabetes to reduce the burden of the disease. KEYWORDS Type-2 Diabetes Mellitus, Thyroid Dysfunction, Hypothyroidism

Association of Hypertension and Ischaemic ECG Changes in Type II Diabetes Mellitus

2019 ◽  
Vol 9 (3) ◽  
pp. 79-83
Author(s):  
Chandra Kala Rai ◽  
Nimesh Poudel
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Type Ii Diabetes Mellitus ◽  
P Value ◽  
Diabetic Patients ◽  
Ecg Changes ◽  
Type 2 Diabetic Patients ◽  
Diastolic Hypertension

 Background: Type 2 diabetes mellitus (T2DM) is one of the most common metabolic disorders to the current generation. It usually leads to multi-system­ic complications such as cardiovascular diseases, proteinuria, micro albumin­uria, retinopathy, hypertension, ischaemic changes and chronic kidney disease. These complications increase the morbidity and mortality of patients. The pro­longed hyperglycemia leads to vascular damage. It causes insufficient blood flow to the cardiac muscles which may cause myocardial or cardiac ischaemia. The aim of this study was to find out the prevalence of hypertension and isch­aemic ECG changes in T2DM patients attending Kathmandu Medical College. Methods: Total 360 type 2 diabetic patients were included. Blood pressure was measured and electrocardiogram (ECG) was recorded by 12 leads ECG. Statistical analysis was done using SPSS version 16. p<0.05 was considered to be statistically significant. Results: The mean age of the patients was 66.88 ± 1.52 years, age ranging from 40 – 95 years. In this study 168 patients (46.66%) had systolic hyperten­sion, 204 patients (56.67%) had diastolic hypertension and 126 (35%) had both systolic and diastolic hypertension. About 103 (28.61%) showed ECG changes in hypertensive patients. Only 4 (1.11%) non- hypertensive had ECG changes. This study showed statistically significant relation of hypertension and isch­aemic ECG changes in type 2 diabetes mellitus cases with p- value 0.03. Conclusions: There is a high prevalence of hypertension among T2DM pa­tients. In these patients, there is a statistically significant association between hypertension and ischaemic ECG changes.

scholarly journals Pulmonary function test in patients of type 2 diabetes mellitus

2019 ◽  
Vol 7 (6) ◽  
pp. 2240
Author(s):  
Amit Agarwal ◽  
Ankit Grover ◽  
Amresh Agarwal
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Pulmonary Function ◽  
Pulmonary Function Test ◽  
General Medicine ◽  
Uttar Pradesh ◽  
Diabetic Patients ◽  
Function Test

Background: We are today witnessing a pandemic of diabetes mellitus (DM), globally and nationally. DM and its complications have become the most important contemporary and challenging health problems. Diabetes is not associated with any specific pulmonary symptom and hence periodic screening for lung disease is not done in diabetic patients. However, an extensive microvascular circulation and an abundant connective tissue in the lung raise the possibility that the lung may also be a target organ in diabetic patients. The aim and objectives were to study the pulmonary function of individual with type 2 diabetes mellitus patients by performing spirometry.Methods: Study included non-smoker diabetic patients, who had no history of respiratory disease, were selected for this study and undergone pulmonary function test by spirometry. The study was conducted at department of General Medicine Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, Uttar Pradesh, India.Results: Present study, author found that there was significant derangement in the spirometric readings in the diabetic patients. The FEV1/FVC values further declines as the duration of diabetes increased.Conclusions: Spirometric values (FVC, FEV1, FEV1/FVC) were consistently lower in subjects with type 2 diabetes mellitus. The effect on FVC predicted % was found to be more pronounced in subjects whose duration of DM was more than 5 years.

scholarly journals Anthropometric and Metabolic Characteristics of Patients with Type 2 Diabetes Mellitus and Hypochromia

2014 ◽  
Vol 21 (4) ◽  
pp. 285-290
Author(s):  
Marius Cristian Neamţu ◽  
Ştefania Crăiţoiu ◽  
Rucsandra Dănciulescu Miulescu ◽  
Denisa Margină
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Common Finding ◽  
Study Patient ◽  
Control Group ◽  
Diabetic Patients ◽  
Metabolic Characteristics ◽  
Patients With Diabetes

AbstractBackground and Aims. Previous studies have shown that hypochromia is a common finding in patients with chronic diseases. The aim of our study was to estimate the anthropometric and metabolic characteristics of patients with type 2 diabetes mellitus (T2DM) and hypochromia. Material and Methods. 30 patients with T2DM were recruited for this study. Patient demographics, relevant concomitant illnesses and medical history were recorded. Anthropometric, biochemical parameters (fasting plasma glucose - FPG, glycated hemoglobin -HbA1c, glomerular filtration rate - GFR) and morphology of blood smear were assessed. Patients diagnosed with diabetes and hypochromia constituted the study group and patients with type T2DM but without hypochromia constituted the control group. Results. The study showed no statistically significant differences on anthropometric and metabolic characteristics of patients with diabetes and hypochromia, compared with controls. Conclusions. We observed a high prevalence of hypochromia in diabetic patients (46.66%). Our findings suggest the need of screening for routine hematological tests in patients with T2DM.

scholarly journals Study of anaemia in type 2 diabetes mellitus

2018 ◽  
Vol 6 (5) ◽  
pp. 1529 ◽  
Author(s):  
Deepali Kaushik ◽  
Raman Parashar ◽  
Praveen K. Malik
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Pearson Correlation ◽  
Diabetic Patients ◽  
Variable Contribution ◽  
Patients With Diabetes ◽  
Unpaired Student ◽  
The Difference

Background: Anaemia is increasingly recognized entity in the patients with diabetes mellitus and constitutes an additional burden in patients. The prevalence of anaemia in the patients with diabetes is two or three times higher than in patients with comparable renal impairment and iron stores in the general population. As India is foreseen a diabetic capital of the world, it becomes imperative to recognize co-morbidities such as anaemia at the earliest. Hence this study is being conducted with the aim to determine the prevalence and various causes of anaemia in diabetics.Methods: After obtaining informed written consent, all diabetics patients were subjected to detailed history, through clinical examination and investigation with CBC, Renal function test including creatinine clearance. The difference of mean between anaemic and non anaemic diabetic patients was evaluated by unpaired student t test. Finally, correlation between the level of haemoglobin and index of renal damage (albumin-creatinine ratio) was accessed by Pearson correlation. Statistical software of SPSS 10 ver. and EXCEL (office 9) was used to analyse the data.Results: In the present study, nearly two third patients of type 2 diabetes mellitus were anaemic. The maximum number of anaemic patients with type 2 diabetes mellitus had microcytic hypochromic type of anaemia.Conclusions: It is therefore concluded that anaemia is a prevalent finding in patients with type 2 diabetes mellitus and represents significant unrecognised burden. The anaemia may be attributed to variable contribution of iron deficiency state and chronic inflammation as result of the disease itself.

scholarly journals Diagnostic Upper Gastrointestinal Endoscopy and Prevalence of Helicobacter Pylori Infection in Dyspeptic Type 2 Diabetes Mellitus Patients

2018 ◽  
Vol 09 (02) ◽  
pp. 053-060 ◽  
Author(s):  
Bhumika T. Vaishnav ◽  
Sameer R. Shaikh ◽  
Arvind A. Bamanikar ◽  
Arjun Lal Kakrani ◽  
Rahul R. Tambile
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Helicobacter Pylori ◽  
Type 2 Diabetes Mellitus ◽  
Common Finding ◽  
Diabetic Patients ◽  
Antral Gastritis ◽  
Patients With Diabetes ◽  
Diabetes Patients

ABSTRACT Introduction: Multisystem involvement is a norm in Type 2 diabetes mellitus (T2DM). Dyspepsia is a common gastrointestinal (GI) tract symptom in people with diabetes. We aimed to study the esophageal, gastric, and duodenal mucosal changes; presence of Helicobacter pylori (HP) infection; and its significance in dyspeptic diabetes patients. Materials and Methods: A prospective observational study done on 287 patients (147 patient with diabetes and 140 nondiabetic controls) with dyspepsia of more than 6 months duration. All patients underwent upper GI endoscopy and evaluation for HP infection. Gross and histopathological examination (HPE) features of biopsies from the esophagus, stomach (fundus, body, and antrum), and duodenum were analyzed and rapid urease test as well as HPE was done for HP detection. Statistical analysis was done and results were expressed as mean ± standard deviation. P < 0.05 was considered to be statistically significant. Results: Average age for dyspeptic T2DM patients was 56.0 ± 8.44 years. Total 67.35% diabetes patients were addicted to tobacco. Epigastric pain and heartburn were the most common symptoms. Antral gastritis was the most common gross (75.08%) and HPE (70.38%) finding in patients with diabetes. In all, 44.21% patients with diabetes tested positive for HP infection, and there was a statistically significant association of HP with T2DM when compared with nondiabetics (P < 0.00001). However, HP infection did not correlate significantly with either glycosylated hemoglobin (HbA1c) or duration of T2DM. Conclusion: Antral gastritis was a common finding in dyspeptic diabetic patients. HP infection although associated with T2DM dyspeptic patients, was not associated with either uncontrolled sugar levels or duration of diabetes.

scholarly journals Prevalence and biochemical correlates of microalbuminuria in type 2 diabetes mellitus at Puducherry, India

2018 ◽  
Vol 5 (4) ◽  
pp. 865
Author(s):  
K. Shaik Anwar Hussain
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Risk Factor ◽  
General Medicine ◽  
Vascular Diseases ◽  
Diabetic Patients ◽  
Early Screening ◽  
Type 2 Diabetic Patients

Background: Microalbuminuria is a risk factor for end stage renal disease as a sequalae of diabetic nephropathy and an independent risk factor for cardio-vascular diseases. Early screening for Microalbuminuria can prevent long-term complications. The objective of the present investigation was to study the magnitude of Microalbuminuria among the patients with type 2 diabetes mellitus attending to the diabetic clinic and correlate with other biochemical parameters related to complications of diabetes.Methods: This observational study was conducted among 500 type 2 diabetic patients attending to the diabetology OPD, Department of General medicine during the time period June 2017 to May 2018. The patients were interviewed for socio-demographic details, history and clinical examination and subjected to blood investigations and ECG.Results: Microalbuminuria was present in 31.6% (n=158) of the diabetics. Age group 45-55 years, male gender, duration of diabetes >10 years, active smokers, Diabetic retinopathy, Peripheral neuropathy, Ischemic heart disease, SBP 160-170 mmHg, DBP 95-100 mmHg and 100-105 mmHg, BMI 30-35 Kg/m2, TG >250 mg/dl, LDL >110 mg/ dl and HbA1c 7.5-9 % showed a greater odds ratio and significant association (p<0.001) with Microalbuminuria.Conclusions: There was an increased prevalence of Microalbuminuria among the patients with type 2 diabetes. It also showed significant association of major microvascular and macrovascular complications of diabetes and Microalbuminuria.

scholarly journals Apolipoprotein A1 level in plasma of patients with diabetes and diabetic patients with COVID-19 as a possible marker of disease

2021 ◽  
pp. 110-113
Author(s):  
M.D. Tronko ◽  
S.A. Cherviakova ◽  
V.V. Pushkarev ◽  
Y.B. Belchina ◽  
O.I. Kovzun ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Density Lipoprotein ◽  
Apolipoprotein A1 ◽  
Enzyme Linked Immunosorbent Assay ◽  
Diabetic Patients ◽  
Patients With Diabetes ◽  
Reduced Risk

Increased levels of high-density lipoprotein cholesterol (HDL-C) and apolipoprotein A1 (ApoA1) in plasma is associated with a reduced risk of developing cardiovascular diseases (CVD). In addition to its potential cardioprotective function, HDL and ApoA1, the main HDL apolipoprotein, also have antidiabetic properties. The aim of the study was to determine the level of ApoA1 in the blood of patients (n = 81) with type 2 diabetes mellitus and COVID-19. ApoA1 was determined by enzyme-linked immunosorbent assay (ELISA) (Elabscience, USA). The measurements were performed at an optical density of 450 nm. We showed that the level of ApoA1 in the blood of patients with type 2 diabetes and especially with COVID-19 was significantly lower than in the blood of healthy people. Blood ApoA1 levels did not show a further decrease in patients with both COVID-19 and diabetes compared with patients with COVID-19 without diabetes. Thus, the level of ApoA1 may be one of the promising markers of severe COVID-19.

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