scholarly journals A chronic case of Madurella mycetoma involving left foot

2019 ◽  
Vol 7 (11) ◽  
pp. 4370
Author(s):  
Alfia Alim ◽  
Binod K. Pati ◽  
Asim Sarfraz ◽  
Sushmita Das
Keyword(s):  
Public Health ◽  
Histopathological Examination ◽  
Subcutaneous Tissue ◽  
Public Health Issue ◽  
Definite Diagnosis ◽  
Chronic Case ◽  
History Of ◽  
Madurella Mycetomatis ◽  
Granulomatous Disorder

Mycetoma is a localized chronic, suppurative, and deforming granulomatous disorder of subcutaneous tissue, skin and bones. Mycetoma is endemic in tropical and subtropical areas, where it is a real public health issue. It is a rare and neglected disease in our country. Etiological classification divides it into eumycetoma caused by fungus, and actinomycetoma caused by bacteria. Since the treatment of these two etiologies is completely different, a definite diagnosis after microbiological and histopathological examination, though difficult, is important. The disease is notoriously difficult to treat. Eumycetoma may be unresponsive to standard antifungal therapy. Authors report a case of eumycetoma in a 38 year-old male from Bihar, with history of thorn prick 30 yrs back. Madurella mycetomatis was isolated from the granular discharge from sinuses and itraconazole was given followed by surgical debridement of the lesion. The patient recovered well and is still on follow up.

A case of nodular episcleritis mimicking a solitary giant episcleral mass

2021 ◽  
pp. 112067212110528
Author(s):  
Lan Zhou ◽  
Juanjuan Wang ◽  
Guihua Xu ◽  
Dingding Wang ◽  
Xiaoyi Wang ◽  
...  
Keyword(s):  
Topical Steroid ◽  
Inflammatory Cells ◽  
Systemic Hypertension ◽  
Eye Drops ◽  
Definite Diagnosis ◽  
Imaging Studies ◽  
Immunohistochemical Examination ◽  
History Of ◽  
Inflammatory Drugs

Purpose To describe an atypical nodular episcleritis mimicking a solitary giant episcleral mass, which is not attributed to any systemic diseases and identified only after immunohistochemical examination. Case report A sixty-year-old Chinese woman with systemic hypertension presented with 6-month history of giant, solitary and redness epibulbar mass arising from the superior aspect of her left eye. The lesion gradually enlarged, even with 6-month history of irregular topical steroid eye drops treatment. Imaging studies and laboratory test revealed a 10 mm × 8 mm episcleral mass absence of any infection indicator and autoimmune antibody changes. The mass was completely removed before its extension through the deep scleral, histopathologic examination revealed a nodular episcleritis composed of various chronic inflammatory cells infiltration. Topical steroid eye drops treatment combined with oral steroidal anti-inflammatory drugs was then administrated regularly for 1 month, and no recurrence occurred after 1-year follow-up. Conclusion Nodular anterior episcleritis is characterized by underlying chronic inflammation of the anterior episclera and can be presented as asymptomatic episcleral mass. Besides a thorough investigation systemically, tissue biopsy is required for definite diagnosis.

scholarly journals Polypharmacy, hospitalization, and mortality risk: a nationwide cohort study

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Tae Ik Chang ◽  
Haeyong Park ◽  
Dong Wook Kim ◽  
Eun Kyung Jeon ◽  
Connie M. Rhee ◽  
...  
Keyword(s):  
Public Health ◽  
Cohort Study ◽  
Prescription Drugs ◽  
Mortality Risk ◽  
Residential Area ◽  
Public Health Issue ◽  
Geriatric Population ◽  
Major Public Health Issue ◽  
Elderly Individuals

Abstract Polypharmacy is a growing and major public health issue, particularly in the geriatric population. This study aimed to examine the association between polypharmacy and the risk of hospitalization and mortality. We included 3,007,620 elderly individuals aged ≥ 65 years who had at least one routinely-prescribed medication but had no prior hospitalization within a year. The primary exposures of interest were number of daily prescribed medications (1–2, 3–4, 5–6, 7–8, 9–10, and ≥ 11) and presence of polypharmacy (≥ 5 prescription drugs per day). The corresponding comparators were the lowest number of medications (1–2) and absence of polypharmacy. The study outcomes were hospitalization and all-cause death. The median age of participants was 72 years and 39.5% were men. Approximately, 46.6% of participants experienced polypharmacy. Over a median follow-up of 5.0 years, 2,028,062 (67.4%) hospitalizations and 459,076 (15.3%) all-cause deaths were observed. An incrementally higher number of daily prescribed medications was found to be associated with increasingly higher risk for hospitalization and mortality. These associations were consistent across subgroups of age, sex, residential area, and comorbidities. Furthermore, polypharmacy was associated with greater risk of hospitalization and death: adjusted HRs (95% CIs) were 1.18 (1.18–1.19) and 1.25 (1.24–1.25) in the overall and 1.16 (1.16–1.17) and 1.25 (1.24–1.25) in the matched cohorts, respectively. Hence, polypharmacy was associated with a higher risk of hospitalization and all-cause death among elderly individuals.

scholarly journals Shigella sonneiBacteremia Presenting with Profound Hepatic Dysfunction

2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Oluwaseun Shogbesan ◽  
Andrew Rettew ◽  
Bilal Shaikh ◽  
Abdullateef Abdulkareem ◽  
Anthony Donato
Keyword(s):  
Laboratory Data ◽  
Abdominal Ultrasound ◽  
The United States ◽  
Shigella Sonnei ◽  
Public Health Issue ◽  
Watery Stool ◽  
Normal Limits ◽  
Significant Public Health ◽  
History Of

Worldwide, Shigellosis is a significant public health issue, associated with nearly one million deaths annually. About half a million cases ofShigellainfection are reported annually in the United States.Shigellabacteremia is uncommon and generally seen in children and immunocompromised adults. We present a case of aShigella sonneibacteremia with marked hepatic derangement in a 27-year-old previously healthy homosexual male with history of Roux-en-Y gastric bypass, who presented to the emergency room with a 4-day history of loose watery stool, abdominal cramps, nausea and vomiting, and yellow skin of 2-day duration. He reports similar diarrhea illness in two close contacts in preceding days. On examination, he was fully oriented but dehydrated, icteric, and febrile. Laboratory data revealed WBC of 2200/μL, elevated AST and ALT (201 IU/L, 73 IU/L resp.), normal alkaline phosphatase, elevated total and direct bilirubin of 8.2 mg/dL and 4.4 mg/dL, albumin of 3.2 g/dL, INR of 2.9, prothrombin time of 31.7, and platelet of 96,000/μL. Workup for infectious, autoimmune and medication-induced hepatitis, Wilson’s disease, and hemochromatosis was negative. Abdominal ultrasound and computed tomography of the abdomen showed hepatic steatosis and right-sided colitis. Stool and blood cultures were positive forShigella sonnei. He was treated with ciprofloxacin with improvement in liver function. Follow-up blood test 4 months later was within normal limits.

scholarly journals Follow-up care of rare diseases in odontology: a public health issue

2012 ◽  
Vol 8 (S1) ◽  
Author(s):  
S Toupenay ◽  
M de la Dure ◽  
N Razanamihaja ◽  
A Berdal ◽  
M-L Boy-Lefèvre
Keyword(s):  
Public Health ◽  
Rare Diseases ◽  
Health Issue ◽  
Public Health Issue ◽  
Follow Up Care

An Unusual Presentation of Ossifying Fibromyxoid Tumor of the Mandible: A Case Report

2007 ◽  
Vol 31 (2) ◽  
pp. 136-138 ◽  
Author(s):  
Nur Mollaoglu ◽  
Benay Tokman ◽  
Sevil Kahraman ◽  
Sedat Cetiner ◽  
Sule Yucetas ◽  
...  
Keyword(s):  
Case Report ◽  
Histopathological Examination ◽  
Subcutaneous Tissue ◽  
Soft Tissue Neoplasm ◽  
Unusual Site ◽  
Clinical Behavior ◽  
Long Term Follow Up ◽  
Ossifying Fibromyxoid Tumor

A 13-year-old boy who complained rapid swelling on the left side of mandible is presented. Histopathological examination revealed ossifying fibromyxoid tumor (OFMT). OFMT is a rare soft-tissue neoplasm that occurs usually in the subcutaneous tissue of the extremities. Head and neck involvement is relatively rare. In this case, we present the diagnosis, surgical treatment and long-term follow-up of an OFMT due to its unusual site of occurrence. The precise clinical behavior of atypical and malignant types of OFMTs is still unclear. Thus, histopathology report is important, leading surgeon to decide how often and how long to follow-up patient with OFMT.

scholarly journals Calcified Right Ventricular Fibroma in an Adult: A Case Report

2021 ◽  
Author(s):  
Huanhuan Gao ◽  
Shuai Yuan ◽  
Zhiqiang Hu ◽  
Zhelan Zheng ◽  
Shengjun Wu
Keyword(s):  
Right Ventricular ◽  
Histopathological Examination ◽  
Tumor Resection ◽  
Anterior Wall ◽  
Benign Tumors ◽  
Troublesome Symptom ◽  
History Of ◽  
The Right ◽  
Operative Recovery

Background: Cardiac fibromas are rare benign tumors of the heart composed of fibroblasts and collagen. They are common among children and adolescents but are rarely present in adults. Case presentation: We here report the case of a fifty-seven-year-old man who complaining of a 2-year history of chest tightness at rest. Transthoracic echocardiography detected a severe calcified mass protruding outside the right ventricular anterior wall near the apex. The patient was referred for tumor resection. The calcified mass was determined to be a cardiac fibroma with postoperative histopathological examination. The patient experienced an unremarkable post-operative recovery and was discharged 8 days later. Subsequent follow-up has shown complete freedom from his troublesome symptom. Conclusions: Preoperative diagnosis with various imaging modalities and early surgery are the keys to improve prognosis of patients with cardiac fibromas.

scholarly journals Oral cancer in Brazil: a secular history of Public Health Policies

2014 ◽  
Vol 62 (2) ◽  
pp. 159-164
Author(s):  
Paulo Ricardo Saquete MARTINS FILHO ◽  
Thiago de Santana SANTOS ◽  
Luiz Carlos Ferreira da SILVA ◽  
Marta Rabello PIVA
Keyword(s):  
Public Health ◽  
Oral Cancer ◽  
Low Income ◽  
Cancer Control ◽  
Public Health Issue ◽  
History Of Public Health ◽  
Assistance Programs ◽  
Control Programs ◽  
History Of ◽  
And Control

The oral cancer in Brazil is considered an important public health issue. Despite almost a century of combat disease, with oncological assistance programs and prevention campaigns based public policies, the incidence of oral cancer in several regions is still high. The major goal of cancer prevention and control is a reduction in both the incidence of the disease and the associated morbidity and mortality, as well as improved life for cancer patients and their families. Low-income and disadvantage groups are generally more exposed to avoidable risk factors such as tobacco and alcohol consumption. These groups have less access to the health services and education that would empower them to make decisions to protect and improve their own health. Thus, cancer control programs are the most effective instrument to bridge the gap between knowledge and practice and achieve this goal. The authors report some key historical facts concerning the fight against oral cancer in Brazil, in addition to addressing the epidemiological aspects of disease.

scholarly journals Histopathological examination of tissues following a surgical uterine evacuation in the first trimester bleeding: clinical relevance

2020 ◽  
Vol 10 (3) ◽  
pp. 91-94
Author(s):  
Bandana Khanal ◽  
Basant Sharma ◽  
Renuka Tamrakar ◽  
Prekshya Singh
Keyword(s):  
Clinical Relevance ◽  
Histopathological Examination ◽  
First Trimester ◽  
Gestational Trophoblastic Disease ◽  
Complete Mole ◽  
Products Of Conception ◽  
Partial Mole ◽  
History Of

Background: There is no general consensus about the role of routine HPE of the obtained tissue at the time of uterine evacuation. However, it is understood clinically that it is of utmost importance to prove the presence of intrauterine gestation and to exclude gestational trophoblastic disease in the form of partial or complete mole. This study aimed to assess the role of histopathology in cases of first trimester miscarriages and to determine clinical relevance of histopathological examination following surgical evacuation. Methods: This was a retrospective study of collected data over 12 months (January 2018- De­cember 2018) in an agency for reproductive health setup with predefined inclusion criteria. We included 60 consecutive patients attended with history of first trimester bleeding. Patient’s record and the histopathological examination report of products of conception following uterine evacu­ation were observed. The data was analyzed descriptive statistics including percentage, stander deviation, mean, and range in Microsoft Excel software. Results: Missed abortion was the most common type and constituted 55% of the studied group. The histopathological reports confirmed the pregnancy in all patients and revealed partial mole in 6(10%) patients and complete mole in 2(3.33%) patients. Conclusions: Histopathological examination of products of conception detects under diagnosed molar pregnancies that necessitates special follow up and is a key step to do further management.

Alcohol

2021 ◽  
pp. 349-360
Author(s):  
Robin Room
Keyword(s):  
Public Health ◽  
Alcohol Problems ◽  
Public Health Issue ◽  
Public Health Approach ◽  
Alcohol Production ◽  
International Convention ◽  
Globalizing World ◽  
New Public ◽  
History Of ◽  
Temperance Movements

This chapter begins with a discussion on alcohol, its uses, and its effects, both positive and negative, followed by a review of the recent research on its cumulative effects on health. The history of alcohol as a public health issue is also briefly reviewed. The temperance movements of the nineteenth and early-twentieth centuries sought to prohibit alcohol altogether, but by the 1930s the alternative of controlling alcohol sales to limit its adverse effects was the dominant aim. As these controls weakened after the 1950s, a ‘new public health’ approach argued for stronger controls. Although this approach gained ground among researchers from the 1970s onwards, it has often been resisted in the policy process. Seven main strategies to prevent or control alcohol problems are described, and their effectiveness briefly assessed. The chapter concludes with an account of alcohol policy in a globalizing world. An international convention on alcohol control has been called for to counter the influence of trade agreements and the globalization of alcohol production, distribution, and promotion.

Thoracic ranula: an extremely rare case

2005 ◽  
Vol 119 (3) ◽  
pp. 233-234 ◽  
Author(s):  
Claudine Elizabeth Pang ◽  
Tee Sin Lee ◽  
Kenny Peter Pang ◽  
Yoke Teen Pang
Keyword(s):  
Chest Wall ◽  
Rare Case ◽  
Subcutaneous Tissue ◽  
Anterior Chest Wall ◽  
Thoracic Wall ◽  
History Of Surgery ◽  
Transcervical Approach ◽  
First Case ◽  
History Of

We present the first case of a thoracic ranula which originated from the left submandibular area extending into the subcutaneous tissue planes of the anterior chest wall. The patient had a history of surgery for a previous benign left salivary gland cyst, and presented with an enlarging mass in the anterior chest wall. This was a recurrence of a ranula, with an extension into the anterior thoracic wall. The thoracic ranula was excised, together with ipsilateral sublingual and submandibular glands, via a transcervical approach. No recurrence was detected over a 3-year post-operative follow up.

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