scholarly journals Histopathological pattern of cutaneous disorders in tertiary care center in Shahjahanpur district of India

2020 ◽  
Vol 8 (7) ◽  
pp. 2531
Author(s):  
Amar Singh ◽  
Astha Pant
Keyword(s):  
Histopathological Examination ◽  
Care Center ◽  
Health Centre ◽  
Tertiary Care ◽  
Skin Lesions ◽  
Cutaneous Tuberculosis ◽  
Younger Age ◽  
Common Group ◽  
Skin Biopsies ◽  
Patient Presentation

Background: Histopathological examination is most commonly needed and used investigation in dermatology. The main objective of this study is to share our experience with skin lesions from a tertiary health Centre by describing the histopathological patterns of 675 consecutive cases.Methods: The study was retrospective and was conducted in those patients who attended the OPD. A total of 675 cases were sent for histopathological examination. Further they were classified into various histological categories based on the site and pattern of involvement. Inclusion criteria involves all skin biopsies sent for histopathology examination, exclusion criteria was none.Results: Most common histopathological entity was infectious disease with 22.52% cases leading in this study. Out of which Hansen disease is on top with 16.29% which was followed by cutaneous tuberculosis with 3.70% (25) cases. Second most common group was of psoriasiform reactions with 9.77% cases. In this group most common disorder was psoriasis vulgaris with 5.92% (40) cases. Third and fourth most common group were spongiotic dermatitis and lichenoid dermatitis which presented with 9.18% and 9.03% cases with a minimal difference of 1 case.Conclusions: A huge diversity in skin lesions was noticed in our study ranging from nonspecific dermatitis to malignant melanoma conditions. There was a younger age predominance regarding the patient presentation. Hansen’s disease still remains a single entity in India for which skin biopsy are required.

scholarly journals Clinicopathological correlation in the diagnosis of granulomatous cutaneous disorders: a retrospective study

2021 ◽  
Vol 7 (4) ◽  
pp. 538
Author(s):  
Manisha Nijhawan ◽  
Divya Yadav ◽  
Shivi Nijhawan ◽  
Damini Shaktawat
Keyword(s):  
Retrospective Study ◽  
Care Center ◽  
Tertiary Care ◽  
Common Type ◽  
Accurate Diagnosis ◽  
Tertiary Care Center ◽  
Clinicopathological Correlation ◽  
Cutaneous Tuberculosis ◽  
Skin Biopsies ◽  
Granulomatous Disorder

<p class="abstract"><strong>Background:</strong> To ascertain the various cutaneous granulomatous disorders and clinicopathological concordance in skin biopsies.</p><p class="abstract"><strong>Methods: </strong>The study included the patients with skin biopsy showing granulomatous infiltrate in a tertiary care center. The cases were categorized according to level of concordance into consistent, corroborative and inconsistent based on the concurrence between clinical and histological diagnosis.</p><p class="abstract"><strong>Results: </strong>Of the total 155 granulomatous disorder, 75.48% showed clinicopathological concordance, 19.35% showed corroborative diagnosis while 5.16% were inconsistent. The maximum number of biopsies performed were in the group of young adult (19-49 years, 57.41%). The most common type of granuloma found was of tuberculoid type and disorders were Hansen’s disease, fungal infection and cutaneous tuberculosis.</p><p class="abstract"><strong>Conclusions:</strong> Our study showed that the coordination of dermatologist and pathologist plays a pivotal role in making accurate diagnosis of granulomatous cutaneous dermatoses.</p>

scholarly journals Profile of Skin Biopsies and Patterns of Granulomatous Skin Diseases in a Tertiary Care Center of Western Nepal

2020 ◽  
Vol 3 (2) ◽  
pp. 288-293
Author(s):  
Ajay Kumar ◽  
Saujan Subedi ◽  
Jenny Pun ◽  
Binamra Basnet ◽  
Raja Babu Giri ◽  
...  
Keyword(s):  
Skin Diseases ◽  
Care Center ◽  
Tertiary Care ◽  
Cost Effective ◽  
Skin Lesions ◽  
Clinical Impression ◽  
Clinicopathological Correlation ◽  
Diagnostic Challenge ◽  
Cross Sectional ◽  
Skin Biopsies

Background: Granulomatous skin diseases are one of the leading causes of morbidity in tropical countries like Nepal. These granulomatous skin lesions often pose diagnostic challenge to clinicians as well as to dermatopathologists. Histopathologic examination of a biopsy specimen represents one of the most informative and cost-effective procedure and may help to avoid other, costlier and invasive diagnostic workup. Materials and Methods: This cross-sectional observational study from October 2018 to October 2019, at department of dermatology, enrolled 142 cases of skin biopsies. Correlation between clinical impression and histopathological findings was evaluated. Results: Out of 13940 dermatology visits/ consultations, 142 (1.01%) skin biopsies were performed. Head, neck and face were the commonest sites of biopsies (29.6%). The most common biopsy technique was incisional type in 70 (50.4%). Histopathology showed granulomatous features in 49 (34.8%) cases, out of which tuberculoid type was the commonest, in 29 (58.0%). Positive clinicopathological correlation was seen in 117/142 (82.4%) for all biopsies and 41/49 (85%) for granulomaous skin lesions. Conclusion: Tuberculoid type was the most common cutaneous granuloma. High clinicopathological correlation in our study supports histopathology as an important tool for diagnosis of granulomatous as well overall skin disorders.

scholarly journals Pigmented Lesions of Skin: A Histopathologic Experience at a Tertiary Care Center in Central Nepal

2021 ◽  
Vol 17 (1) ◽  
pp. 1-9
Author(s):  
Binita Goyal ◽  
Suman Rai ◽  
Mamata Sedhain ◽  
Pratigya Subedi
Keyword(s):  
Cell Carcinoma ◽  
Malignant Tumors ◽  
Histopathological Examination ◽  
Care Center ◽  
Tertiary Care ◽  
Skin Lesions ◽  
Histopathological Diagnosis ◽  
Female Ratio ◽  
Pigmented Lesions ◽  
Pigmented Skin Lesions

Introduction Pigmented skin lesions refer to lesions that are brown, black or blue in color. These are not always melanocytic in origin. Keratinocytic, vascular or reactive pigmentation in other lesions can also appear pigmented. The main aim of the study was to see the histopathological spectrum and objective was to compare clinical and histopathological diagnoses in pigmented skin lesions. Methods This descriptive study was carried out on 43 pigmented skin lesions that were biopsied over a 1 and half year period from Jan 2018 to June 2019 in College of Medical Sciences and Teaching Hospital. Results Age of the patient ranged from 10 to 88 years and mean±SD was 42.02±19.73 years. There were 21 (48.8%) males and 22 (51.2%) females with a male female ratio 0.9:1. Melanocytic nevus was the most common histopathological diagnosis (11 cases, 25.6%). Reactive pigmentation was seen in 20 (46.5%) cases. Malignant cases comprised 6 (14.0%) cases which included 2 (4.7%) cases of melanoma, 2 (4.7%) cases of pigmented basal cell carcinoma and 1 (2.3%) case each of basaloid squamous cell carcinoma and trichoblastic carcinoma each. Clinicopathological agreement could be seen in 32 (74.4%) cases. However, malignancy was clinically suspected in only half of histologically diagnosed cases. Conclusions Melanocytic nevi were the most common pigmented lesions diagnosed. Not all pigmented lesions are melanocytic in origin. Malignant tumors can sometimes appear deceptively benign and also tumors other than melanoma can be pigmented. Hence, histopathological examination remains the gold standard in diagnosing these conditions and guiding appropriate management. Keywords: melanocytic; melanoma; nevus; pigmented.  

scholarly journals Clinico-pathological and radiological correlation of sino-nasal masses in a tertiary care center

2020 ◽  
Vol 6 (7) ◽  
pp. 1342
Author(s):  
Dimple Sahni ◽  
Gagandeep Kaur ◽  
Peeyush Verma ◽  
Rajwant Kaur ◽  
Harpal Singh
Keyword(s):  
Histopathological Examination ◽  
Care Center ◽  
Tertiary Care ◽  
Inflammatory Lesion ◽  
P Value ◽  
Radiological Investigation ◽  
Female Ratio ◽  
Histopathological Correlation ◽  
Neoplastic Lesion ◽  
Neoplastic Lesions

<p class="abstract"><strong>Background:</strong> The nasal masses are most commonly encountered condition in outpatient department of otorhinolaryngology. The purpose of this study was to show the clinical, radiological and histopathological correlation of sino nasal masses.</p><p class="abstract"><strong>Methods:</strong> This study was conducted on 100 cases with sino nasal masses over a period of 2 years. A provisional diagnosis was made after clinical and radiological investigation which was confirmed with histopathological examination and the findings were correlated.  </p><p class="abstract"><strong>Results:</strong> The number of non-neoplastic lesions were more than neoplastic lesions (75% vs 25%). Incidence was highest in the age group of 31-40 year (21%) with male to female ratio of 1.5:1. In our study among non-neoplastic lesion, inflammatory lesion had highest frequency (75%). We found clinical and histopathological correlation in 94.6% cases (p value 0.04). 93.33% cases correlated radiologically and histopathologically (p value 0.04).    </p><p class="abstract"><strong>Conclusions:</strong> We concluded that for proper evaluation of sino nasal masses, clinical, radiological, histopathological evaluation should be carried out conjointly. Histopathologic evaluation remains the gold standard.</p>

scholarly journals Study of maternal and perinatal outcome of referred patients in tertiary health centre

2017 ◽  
Vol 6 (12) ◽  
pp. 5363
Author(s):  
. Jyotsana ◽  
Lalit D. Kapadia ◽  
Hafsa Vohra
Keyword(s):  
Care Center ◽  
Health Centre ◽  
Tertiary Care ◽  
Morbidity And Mortality ◽  
Child Health Services ◽  
Tertiary Care Center ◽  
Perinatal Morbidity ◽  
Hypertensive Disorders Of Pregnancy ◽  
Hypertensive Disorders ◽  
Common Diagnosis

Background: Referral services for identification and referral of high risk pregnancies are an integral part of maternal and child health services. The aim of this study was to review the pattern of obstetric cases referred to tertiary care center, to identify their clinical course, mode of delivery, maternal and perinatal outcomes.Methods: It is a prospective observational study carried out from January 2017 to July 2017. Study population was all Obstetrics patients referred to Department of Obstetrics and Gynecology of B.J Medical College, Ahmedabad, Gujarat, India a tertiary care center during the study period.Results: The total number of referred cases in above study period was 100. Mode of transport used by the referred patients was by 108 ambulances (75%) and private vehicles (25%). Most common diagnosis at the time of referral was hypertensive disorders of pregnancy (31%). Out of the total referred cases, 57% had vaginal delivery, 42% had caesarean section. Hypertensive disorders of pregnancy constitute the leading cause of maternal deaths amongst the referred cases.Conclusions: The present study has shown that inadequate antenatal and intra-natal care at the periphery level is responsible for increased maternal and perinatal morbidity and mortality. Even today, hypertensive disorders of pregnancy are the leading cause of maternal mortality. Health education to the community will definitely reduce maternal and perinatal morbidity and mortality.

scholarly journals A clinico-pathological study of patients with thyroid swelling and their management in a tertiary care centre in western Uttar Pradesh

2021 ◽  
Vol 12 (1) ◽  
pp. 95-99
Author(s):  
Mohini Tyagi ◽  
Probal Chatterjee
Keyword(s):  
Thyroid Disease ◽  
Multinodular Goiter ◽  
Clinical Presentation ◽  
Histopathological Examination ◽  
Care Center ◽  
Tertiary Care ◽  
Pathological Study ◽  
Tertiary Care Centre ◽  
Benign Condition ◽  
Thyroid Swelling

Background: Thyroid diseases are common worldwide and in India too there is a significant burden of thyroid disease. Thyroid disease has a reported prevalence of 4-7% in the general population on neck palpation and in autopsy series it may be as high as 50% if subclinical nodules are included. The clinical presentation of thyroid swellings can be very misleading and a definitive diagnosis cannot be done without proper investigations. Aims: To conduct a clinic-pathological study of thyroid swellings along with their management in a tertiary care center. Objectives: 1. To study the various clinical presentations of thyroid swellings 2. To record the FNAC findings in each case. 3. To perform histopathological examination of all operative specimens and compare the results with preoperative diagnosis. Materials and Methods: A one-year prospective study was done in which 50 patients with thyroid swelling were identified. Detailed information regarding all relevant parameters was recorded and treatment was done as per standard protocol. Results: Female preponderance of cases was seen (3.16:1). Maximum cases were in 36-45 year age group and 70% cases were premenopausal females. Multinodular goiter was commonest clinical presentation and colloid goiter was most common FNAC finding. Hemithyroidectomy was the most frequently performed operation. Final results showed that colloid goiter was the most commonly diagnosed benign condition while papillary carcinoma was the commonest malignancy. Conclusion: Most studies show female preponderance of cases. Multinodular goiter is the commonest clinical presentation world-wide. Colloid goiter is the most commonly diagnosed cause of thyroid swelling. Though FNAC is not 100% accurate, it has an important role in the initial evaluation of these patients. Histopathogical examination of specimen is the gold-standard investigation for final diagnosis. Due to the risk of an underlying malignancy, a proper evaluation of thyroid swellings is a must as they have excellent cure rate if treated early.

scholarly journals A study of impairment and disability among elderly and its effect on health-related quality of life

2019 ◽  
Vol 6 (12) ◽  
pp. 5310
Author(s):  
Apurva Kamat ◽  
Hemangini K. Shah
Keyword(s):  
Quality Of Life ◽  
Care Center ◽  
Health Centre ◽  
Tertiary Care ◽  
The Elderly ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Domain Scores

Background: Ageing is generally defined as a process of deterioration in the functional capacity of an individual that results from structural changes, with increasing age. Although old age is not a disease in itself; the elderly are vulnerable to chronic diseases like cardiovascular illnesses, cancers, diabetes etc. leading to impairment and disabilities affecting the health related quality of life of the elderly (HRQOL), which has become an increasingly important outcome in public health research. The main aim is to estimate the common impairments and disabilities among elderly and its effect on their health-related quality of life.Methods: In the community based cross-sectional study, among 171 elderly (more than or equal to sixty years of age) selected from the field practice area of Urban Health Centre of a tertiary care center, Goa, through simple random sampling technique, the data was collected using a pre designed structured questionnaire eliciting previously diagnosed health related conditions, SF-36 HRQOL questionnaire and a detailed general examination. Data was analysed using Epi Info version 7.00 statistical package and various tests of significance were used.Results: Of total of 171 elderly, 56.14% were impaired. The HRQOL and domain scores decreased with increasing age with lower mean scores in females than males (p=0.039). Age, marital status, three generation families, absence of co-morbidities, impairment and disability, education, occupation were significant favorable influences on the HRQOL in (total and domain scores), role of physical domain being the most commonly affected.Conclusions: The increasing population of elderly more so the female elderly population, the emergence of double burden of communicable and non-communicable diseases, presence of impairments and disabilities severely affects their HRQOL.

scholarly journals Oral pemphigus vulgaris: clinicopathological study of 35 cases at a tertiary care centre in North India

2017 ◽  
Vol 3 (2) ◽  
pp. 192
Author(s):  
Ameesha Mahajan ◽  
Jasleen Kaur ◽  
Mridu Manjari ◽  
Saurabh Sharma ◽  
Pooja Bains ◽  
...  
Keyword(s):  
Histopathological Examination ◽  
Tertiary Care ◽  
Pemphigus Vulgaris ◽  
Skin Lesions ◽  
Punch Biopsy ◽  
North India ◽  
Tertiary Care Centre ◽  
Present Specimen ◽  
Female Ratio ◽  
Oral Ulcers

<p class="abstract"><strong>Background:</strong> The purpose of the study was to evaluate the clinical and histopathological features of oral pemphigus vulgaris<span lang="EN-IN">.</span></p><p class="abstract"><strong>Methods:</strong> A prospective study of 35 cases of oral pemphigus vulgaris, over a period of 2.5 years from June 2014 to December 2016 in the Department of Dermatology, Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar was designed. Complete history and detailed mucocutaneous examination was done. Punch biopsy was performed from the oral mucosa and skin lesions (if present). Specimen was sent for histopathological examination and results analysed.<strong></strong></p><p class="abstract"><strong>Results:</strong> Out of 35 patients, 17 (48.57%) were males and 18 (51.42%) were females. Male to female ratio was 1:1.1. The majority of the patients (12, 34.29%) were in the 40-49 year age group. Multiple sites were involved in all patients with bilateral buccal mucosa being involved in all the cases, followed by tongue (30, 85.71%). Histopathological examination showed presence of suprabasal split and acantholytic cells in all cases<span lang="EN-IN">. </span></p><p class="abstract"><strong>Conclusions:</strong> <span>Oral ulcers are a presenting feature of pemphigus vulgaris which commonly precede the skin lesions. Histopathological examination enables early diagnosis of the disease which leads to prompt treatment and decreased morbidity</span><span lang="EN-IN">.</span></p>

scholarly journals Clinical profile of rhinosporidiosis in a tertiary care center of an endemic area

2018 ◽  
Vol 4 (3) ◽  
pp. 659 ◽  
Author(s):  
Suneer R. ◽  
Sivasankari L.
Keyword(s):  
Tamil Nadu ◽  
Endemic Area ◽  
Histopathological Examination ◽  
Care Center ◽  
Tertiary Care ◽  
Granulomatous Inflammation ◽  
Clinical Profile ◽  
Medical College ◽  
Male Preponderance ◽  
A Prospective Study

<p class="abstract"><strong>Background:</strong> Rhinosporidiosis is a chronic granulomatous inflammation caused by <em>Rhinosporidium seeberi</em>. It is water borne disease endemic in Kanyakumari district of South India. The objective of the study was to study the clinical profile of rhinosporidiosis in an endemic area of Kanyakumari district</p><p class="abstract"><strong>Methods:</strong> This is a prospective study of 50 surgically treated cases of rhinosporidiosis carried out in the department of ENT, Kanyakumari Government Medical College from January 2016 to December 2017. All were diagnosed on clinical basis and were treated by excision and electrocautery of the base. The specimens were sent for histopathological examination.  </p><p class="abstract"><strong>Results:</strong> The cases in this study were in the age group between 6 to 70 years. Of these 38 were males and 12 were females indicating a male preponderance. The main presenting symptom was epistaxis in about 80% cases. Nose is the common site involved. Extra nasal spread is common in recurrent cases.</p><p class="abstract"><strong>Conclusions:</strong> The study reflects the endemicity of this disease in Kanyakumari district of Tamil Nadu. High incidence is noted in those bathing in ponds. Extra nasal spread is common in recurrent cases and raising health awareness will go a long way in decreasing its incidence.</p><p class="abstract"> </p>

scholarly journals Histomorphological analysis and clinical correlation of neoplastic and non neoplastic skin lesions: a study in a tertiary care centre of Western Uttar Pradesh, India

2020 ◽  
Vol 8 (8) ◽  
pp. 2820
Author(s):  
Mithila Bisht ◽  
Anjana Arya ◽  
B. C. Choudhry
Keyword(s):  
Histopathological Examination ◽  
Tertiary Care ◽  
Uttar Pradesh ◽  
Skin Lesions ◽  
Punch Biopsy ◽  
Histopathological Analysis ◽  
Histopathological Diagnosis ◽  
Tertiary Care Centre ◽  
Male Predominance ◽  
Dermatological Disorders

Background: Clinical examination may suffice in making diagnosis of most dermatologic disorders but histopathological examination is often required to confirm the diagnosis and further categorize the lesions. Authors carried out this study to analyse the demographic and histomorphological characteristics of skin lesions, to determine the frequency of various dermatological disorders in the region and to evaluate the agreement between clinical and histopathological diagnosis.Methods: Punch biopsies of skin lesions received in histopathology section, were included in the study. Cases over a period of six months were analysed. Clinical details were recorded and histopathological analysis done. Special stains were applied wherever required.Results: Of the 120 cases studied, maximum cases fell in the category of 31-40 years, with male predominance.  Authors observed wide variety of non-neoplastic and neoplastic lesions. Infectious diseases were the most common of all pathologies. Leprosy was the most common histopathological diagnosis. Complete clinicopathologic correlation was seen in 51.67% of cases while partial correlation was noted in 23.33% making a total of 75%. 25% histopathological diagnosis were inconsistent with the clinical diagnosis.Conclusions: Histopathology is a gold standard investigation and plays a very important role in confirmation of clinical diagnosis of various skin lesions. Punch biopsy is a relatively easy outpatient procedure to perform.

Sign in / Sign up

Export Citation Format

Share Document