Variability of IOP following laser photocoagulation used in the treatment of diabetic retinopathy

Background: Diabetic retinopathy (DR) is the leading cause of blindness in most industrialized countries. This study was undertaken to assess the variability of IOP following laser photocoagulation used in the treatment of diabetic retinopathy.Methods: This study was conducted at Department of Opthalmology, B.R.D. Medical College, Gorakhpur from June 2015 to December 2016. This study was intended to see the onset and duration of intraocular pressure spikes in diabetic retinopathy patients after green laser photocoagulation (532 nm) (Nidek). Forty patients were followed for next 3 months. The data was analysed by using SPSS version 15.0. Chi-square test and T test was used.Results: Out of 40 patients, 2 (5%) had background Diabetic retinopathy (DR) with maculopathy, 10 (25%) having pre-proliferative DR, 28 (70%) having proliferative DR. Out of 2 BDR patients, 1 (50%) developed immediate post laser angle closure (Schaffer's grade 1) which persisted for 3 days and another had shown no change in angle structure. Out of 10 PPDR patients, no one developed post laser angle closure (0%). Out of 28 PDR patients, 6 (21.4%) had post laser angle closure which included 4 patients who had angle closure before laser, that means around 7% patients developed angle closure in this group. Among these 2 patients, 1 developed angle closure immediately (Schaffer's grade 1) and another developed the same 1 day later and this angle closure (Schaffer's grade 1) remained for 3 days.Conclusions: Laser photocoagulation in diabetic retinopathy patients can cause increase in IOP.

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Perceptions of Final Year Medical Students about Family Medicine as A Career Choice in Pakistan

Pakistan Journal of Medicine and Dentistry ◽

10.36283/pjmd9-1/023 ◽

2020 ◽

Author(s):

Dur-e- Nishat

Keyword(s):

Medical Students ◽

Family Medicine ◽

Medical Profession ◽

Healthcare Services ◽

Developed Countries ◽

Cross Sectional Study ◽

Chi Square ◽

Cross Sectional ◽

Medical College ◽

Chi Square Test

Background: Family medicine is a field in which complete and detailed set of healthcare services are provided to the patients and their families. In developed countries, freshly graduated students choose family medicine as a priority for their career. However, in Pakistan it is not the case. The present study is undertaken to determine the perceptions of final year medical students’ about Family Medicine as a viable career. Methods: A total number of 504 students participated in the study. This was a cross-sectional study. The study participants were in their final year of medical college. Data was collected using a preapproved questionnaire. Data was entered and analyzed via SPSS version 17 and Chi-Square test was used post-stratification. Results: Only 14.3% (n=72) medical students had heard about Family Medicine. Only 18% (n=92) would select family medicine as a profession. The most frequent rationale for choosing the field of Family Medicine was the variety of patients seen in general practice (55.4% n=51). Conclusion: There is a dire need to focus on increasing awareness about the field of family medicine among medical students. The students should be counseled on the advantages along with the disadvantages of choosing this field as a medical profession.

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Knowledge of Pressure Ulcer Management among Nurses

Journal of Gandaki Medical College-Nepal ◽

10.3126/jgmcn.v9i2.17869 ◽

2017 ◽

Vol 9 (2) ◽

pp. 47-51 ◽

Cited By ~ 2

Author(s):

Nisha Shrestha ◽

P Shrestha

Keyword(s):

Pressure Ulcer ◽

College Teaching ◽

Cross Sectional Study ◽

Current Evidence ◽

Chi Square ◽

Cross Sectional ◽

Medical College ◽

Adequate Knowledge ◽

Chi Square Test ◽

Experience Education

Background: Pressure ulcer (PU) development remains a significant complication among at-risk patients. It is considered “never events” because they are preventable and should “never” happen. It has been associated with increased morbidity, mortality, hospital cost and length of stay in the hospital. Prevention of pressure ulcers is considered a nurse-sensitive indicator hence nurses should have adequate knowledge about current evidence-based prevention and management of pressure ulcer. However, non adherence to these guidelines is frequent and lack of knowledge may act as barriers to using guidelines in clinical practice.Objectives: The objectives of the study were to 1. assess the knowledge of pressure ulcer management among nurses 2. determine the level of knowledge of pressure ulcer management among nurses 3. assess the association of knowledge of nurses and baseline variables.Methods: A descriptive cross sectional study was conducted, using pretested self administered questionnaire to assess the knowledge on pressure ulcer management among purposively selected 100 nurses working in Gandaki Medical College Teaching Hospital in 2015. Descriptive statistics as frequency and percentage were used and inferential statistics (Chi-square test) was done to find out association between knowledge and selected baseline variables.Results: The study revealed that 59% of the respondents had adequate knowledge where as 41% of nurse’s knowledge was found to be inadequate. Significant association was not found between age, working ward, experience, education, training, duration and knowledge of pressure ulcer management among Nurses.Conclusion: This result indicates that more than half of the nurses had the adequate knowledge but there is still need of education and training related pressure ulcer management.Journal of Gandaki Medical CollegeVolume, 09, Number 2, July December 2016, Page: 47-51

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ANTIBIOGRAM PROFILE AND BIOFILM FORMING POTENTIAL OF PSEUDOMONAS SPECIES ISOLATED FROM VARIOUS CLINICAL SPECIMENS

Asian Journal of Pharmaceutical and Clinical Research ◽

10.22159/ajpcr.2018.v11i10.25518 ◽

2018 ◽

Vol 11 (10) ◽

pp. 150

Author(s):

Jamsheera Cp ◽

Ethel Suman

Keyword(s):

Biofilm Formation ◽

Susceptibility Testing ◽

Diffusion Method ◽

Resistance Pattern ◽

Chi Square ◽

Clinical Specimens ◽

Medical College ◽

Biofilm Production ◽

Pseudomonas Species ◽

Chi Square Test

Objective: The present study aimed at finding the resistance pattern of Pseudomonas aeruginosa and other Pseudomonas species isolated from various clinical specimens in the laboratory.Methods: A total of 150 isolates of different species of Pseudomonas obtained from various clinical specimens processed at the Microbiology laboratory of Kasturba Medical College, Manipal Academy of Higher Education, were taken for this study. Antibiotic susceptibility testing was performed by Kirby-Bauer disc diffusion method and interpreted according to the CLSI guidelines. Biofilm assay was performed by modified O’Toole and Kolter method. The results were analyzed using SPSS 17.0 and Student’s unpaired t-test, Kruskal–Wallis, Mann–Whitney, ANOVA, and Chi-square test. p<0.05 was considered statistically significant.Results: Increased resistance was observed by P. aeruginosa to cefotaxime, cotrimoxazole, levofloxacin, ofloxacin, and ticarcillin clavulanate. There was also a good correlation between antibiotic resistance to aztreonam, netilmicin, and ceftazidime and biofilm production. Results of the present study, therefore, demonstrated the occurrence of resistance to various antipseudomonal agents among the biofilm-producing P. aeruginosa isolates.Conclusion: The present study may help in assessing the seriousness of drug resistance caused by biofilm formation in P. aeruginosa and devise strategies through antibiotic policies to minimize such problems.

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Safety and efficacy of 532 nm frequency-doubled Nd-YAG green laser photocoagulation for treatment of retinopathy of prematurity

Indian Journal of Ophthalmology ◽

10.4103/ijo.ijo_325_19 ◽

2019 ◽

Vol 67 (6) ◽

pp. 860 ◽

Cited By ~ 1

Author(s):

MangatR Dogra ◽

SimarRajan Singh ◽

Deeksha Katoch ◽

Sabia Handa ◽

Savleen Kaur ◽

...

Keyword(s):

Retinopathy Of Prematurity ◽

Laser Photocoagulation ◽

Green Laser ◽

Safety And Efficacy ◽

532 Nm

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ULTRASOUND PREDICTABILITY OF LOWER UTERINE SEGMENT CESAREAN SECTION SCAR THICKNESS

10.36106/ijsr/3520656 ◽

2020 ◽

pp. 9-11

Author(s):

Madhu Kumari ◽

Kumari Bibha ◽

Abha Sinha ◽

Debarshi Jana

Keyword(s):

Cesarean Section ◽

Gestational Age ◽

Statistical Significance ◽

P Value ◽

Chi Square ◽

Medical College ◽

Chi Square Test ◽

Uterine Scar ◽

Age Range ◽

The Given

Objective: The objective of this study is to find out association between scar thickness, assessed sonographically, and intraoperative findings (IOF). Study Design: Descriptive study. Place and Duration of Study: Department of Obstetrics and Gynecology, Sri Krishna Medical College and Hospital, Muzaffarpur, Bihar from June 2019 to May 2020. Methodology: A total of 70 pregnant patients were included in this study. Transabdominal ultrasound was done for scarred uteri. Sonographic findings were co-related with introperative findings. All the given data were entered on SPSS version 23. Age was expressed as mean ± SD. Parity, gestational age, and interval between cesarean sections were expressed as frequencies with percentages. Statistical analysis was done by using Chi-square test for categorical data for association between sonographic scar thickness and intraoperative findings. The statistical significance was set at p-value <0.05. Results: The age range of the patients was 20- 36 years with a mean of 27.91 ±3.690 years. Gestational age at the time of cesarean section was between 27-40 weeks of gestation with a mean of 37 ±2.126 weeks. The interval from previous cesarean was 10 months at the minimum, and 6 years at the maximum with a mean of 2.29 ±1.0 months. Mean scar thickness was 2.5 mm. Association between scar thickness (<1-3 mm) and intaoperative findings of dehiscence and rupture showed a p-value of <0.001. Conclusion: Sonographic assessment of a uterine scar has a practical application to determine the thickness of previous scar, and assess its integrity.

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N-Acetyl Cysteine Ameliorates Hepatotoxicity Associated with the Use of Methotrexate in Mice

10.53350/pjmhs211551008 ◽

2021 ◽

Vol 15 (5) ◽

pp. 1008-1010

Author(s):

Aamna Khokhar ◽

Iram Kehkashan Khurshid ◽

Sadia Lodhi ◽

Alia Sarfaraz ◽

Muhammad Arif ◽

...

Keyword(s):

Histopathological Examination ◽

Controlled Trial ◽

Protective Role ◽

Ethical Review ◽

Trial Methodology ◽

Chi Square ◽

Medical College ◽

Respective Treatment ◽

Chi Square Test ◽

Post Hoc

Background: Liver is not only involved in maintaining homeostasis but also exhibits significant role in metabolism and detoxification of various drugs and toxins. Aim: To explore the hepato-protective role of N-acetylcysteine against methotrexate induced hepato-toxicity. Study design: Randomized controlled trial. Methodology: This study having mice (n=18) was carried out after ethical review committee’s (ERC) approval at Foundation university medical college in collaboration of National institute of health, Islamabad in 2017. Single intraperitoneal injection (20mg/kg) of methotrexate induced hepato-toxicity. Hepatoprotective effect was assessed by oral administration N-acetylcysteine (50mg/kg) alone with methotrexate. The extent of liver damage and effect of protective agents were determined by measuring serum ALT, AST, ALP after 24 hours of respective treatment. Liver samples were taken for histological analysis. One way ANOVA followed by Post Hoc Tukey test was applied for multiple comparisons of biochemical markers between the groups. Histopathological findings were analyzed by Chi Square test. p < 0.05 was considered significant. Results: Significant (p < 0.05) hepatotoxicity was seen with substantial elevation in serum ALT, AST and ALP with methotrexate. N-acetylcysteine attenuated the methotrexate induced hepatotoxicity significantly (p < 0.05). The histopathological examination showed mild steatosis along with focal pleomorphism in the liver of mice that received methotrexate in comparison to group treated with N-acetylcysteine and methotrexate though minimal inflammation was seen. Conclusion: We concluded that N-acetylcysteine ameliorates the methotrexate induced hepatotoxicity on when used concomitantly. Keywords: Hepatotoxicity, N-acetylcysteine and Methotrexate

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Variations in the course and branching pattern of musculocutaneous nerve

National Journal of Clinical Anatomy ◽

10.1055/s-0039-3401720 ◽

2013 ◽

Vol 02 (04) ◽

pp. 195-199

Author(s):

Amar Jayanthi A. ◽

Arunkumar K G.

Keyword(s):

Median Nerve ◽

Growth Cone ◽

Single Case ◽

Clinical Importance ◽

Anatomical Variations ◽

Musculocutaneous Nerve ◽

Axonal Pathfinding ◽

Chi Square ◽

Medical College ◽

Chi Square Test

Abstract Background and aim: The variations in the course and communicating branches of musculocutaneous nerve is of clinical importance in the treatment of recurrent compression neuropathies and in the diagnosis of median nerve lesions. Most of the reports on anatomical variations of musculocutaneous nerve are single case studies and such studies with emphasis on gender difference in a sample of Keralite population are rarely reported. The objective of the present study is to observe the variations in the course of musculocutaneous nerve with special reference to communications with other nerves of the arm and to study the correlation between gender and variations of the nerve. Materials and Methods: Two hundred and sixty four arms were dissected in the department of Anatomy, Government medical college, Thrissur and studied for variations of muculocutaneous nerve. Analysis was done with epi info, using proportions, confidence interval and Chi Square test. The communications noted were classified using the available classifications of Le Minor, Venieratos and Anagnostopoulou and Choi et al. Results: Nerve variations were seen in 24.2 % cases which include, absence of the nerve (3.4%), nerve not piercing coracobrachialis (12.4%) and communication to median nerve (15.1 %). All the variations observed were statistically not significant. The embryological basis for the axonal pathfinding is considered as a result of both guidance molecules and electrical activity that change the calcium homeostasis within the growth cone to regulate growth cone turning. Conclusion: Variations that were observed in the present study may give sufficient and relevant data on the nerves, among Keralite population in which studies are few.

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Anxiety and Academic Performance among Private Medical College Students

Journal of Current and Advance Medical Research ◽

10.3329/jcamr.v5i2.37066 ◽

2018 ◽

Vol 5 (2) ◽

pp. 68-72 ◽

Cited By ~ 1

Author(s):

Shila Rani Das ◽

Chinmay Biswas

Keyword(s):

Academic Performance ◽

Medical Students ◽

Nuclear Family ◽

Strong Association ◽

Cross Sectional Study ◽

Chi Square ◽

College Hospital ◽

Cross Sectional ◽

Medical College ◽

Chi Square Test

Background: Medical students are in a huge pressure due to their academic syllabus. Objective: The purpose of the present study was to assess the relationship between anxiety and academic performance among private medical college.Methodology: This cross sectional study was done in private medical College Hospital, Dhaka, Bangladesh and 3rd and 4th year medical student were included. Data was collected by using semi structured Socio-demographic questionnaire and Burn Anxiety Inventory scale and Checklist. Finally all data and results were analyzed using latest version of SPSS software. For descriptive statistics means, medians, SD and range will be calculated as required. Data will be presented in frequency table, bar, pie and scattered diagram as per need. Statistical test chi-square test were used and p<0.05 was consider to be statistically significant.Results: A total number of 200 medical students were studied after fulfilling the inclusion and exclusion criteria. Among them 87.0% were Muslim; 98.0% were unmarried; 83.0% were in nuclear family; family member of 42.5% respondents had 4 to 6 persons; monthly income of 64.7% respondents were less than 50,000 Taka; 47.0% of the respondents’ father occupation was businessman. In 1st profession examination 68.0% in Anatomy, 73% in Physiology, 76% in Biochemistry were passed in anatomy. In 1st professional exam, students suffered from moderate to extreme anxiety were passed 78% and referred 22% as well as suffered from minimal to mild anxiety were passed 43% and referred 57% in Physiology. So there was strong association between the two variables (p<0.05).Conclusion: Three fifth of the students are suffered from moderate anxiety level and those who are suffered moderate to extreme anxiety passed more and their class attendance are good.Journal of Current and Advance Medical Research 2018;5(2):68-72

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FREQUENCY, DISTRIBUTION AND DETERMINANTS OF HYPERTENSION IN ADULT STROKE POPULATION OF D.I.KHAN DIVISION, PAKISTAN

Gomal Journal of Medical Sciences ◽

10.46903/gjms/17.03.2076 ◽

2020 ◽

Vol 17 (3) ◽

pp. 81-89 ◽

Cited By ~ 1

Author(s):

Nazafatul Ain ◽

Saira Khan ◽

Muhammad Marwat ◽

Nisar Khan ◽

Iftikhar Ahmad ◽

...

Keyword(s):

Frequency Distribution ◽

Goodness Of Fit ◽

Age Groups ◽

Cross Sectional Study ◽

Age Group ◽

Chi Square ◽

Cross Sectional ◽

Medical College ◽

Stroke Population ◽

Chi Square Test

Background: Global Health Estimates 2015 has shown the stroke as second leading global cause of death and 3rd leading global cause for DALYs for year 2015. The objectives of this study were to determine the frequency, distribution and determinants of hypertension in adult stroke population of D.I.Khan Division, Pakistan. Materials & Methods: This cross-sectional study was conducted in Department of Community Medicine, Gomal Medical College, D.I.Khan, Pakistan from February 1, 2017 to April 30, 2017. A sample 217 was selected with margin of error 5.59%, 90%CL and 50% prevalence of hypertension in 200,000 adults at risk of stroke population through consecutive sampling. All indoor adult patients of stroke were eligible. Sex, age groups, and residence and presence of hypertension were variables. Frequency and distribution of hypertension were analyzed by count and percentage. Hypotheses for distribution were substantiated by chi-square goodness-of-fit and of association by chi-square test of association. Results: Out of 217 patients with stroke, 123 (56.7%) were men and 94 (43.3%) were women, 86 (39.6%) were≤60 years and 131 (60.4%) were>60 years, and 105 (48.4%) were urban and 112 (51.6%) were rural. Frequency of hypertension was 132/217 (60.83%). Out of 132 patients with hypertension, men were 74 (34.10%), women 58 (26.73%), age group≤60 years 46 (21.20%), >60 years 86 (39.63%), urban 72 (33.18%) and rural 60 (27.65%). Presence of hypertension was associated to residence (p=.023) but not to sex (p=.817) and age groups (p=.072). Conclusion: Frequency of hypertension in adult stroke population of D.I.Khan Division, Pakistan was found to be similar as expected. Frequency was more in men, in older age group (of>60years) and in urban population. The presence of hypertension in adult stroke population of D.I.Khan Division was associated to residence but not to sex and age groups.

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Sleep disturbance and its effect on academic performance among students of a medical college of Tripura

International Journal of Community Medicine and Public Health ◽

10.18203/2394-6040.ijcmph20185261 ◽

2018 ◽

Vol 6 (1) ◽

pp. 293 ◽

Cited By ~ 2

Author(s):

Anjan Datta ◽

Kaushik Nag ◽

Nabarun Karmakar ◽

Tamal Chakrabarty ◽

Kaushik Tripura ◽

...

Keyword(s):

Academic Performance ◽

Medical Students ◽

Sleep Disturbance ◽

Simple Random Sampling ◽

Cross Sectional Study ◽

Chi Square ◽

Cross Sectional ◽

Medical College ◽

Disturbed Sleep ◽

Chi Square Test

Background: Sleep deprivation may have grave health consequences; resulting in increasing disease morbidity and mortality. Sleep disturbance have also been affected academic performance of medical students. The objective of the study was to find out the prevalence of sleep disturbance and association between sleep disturbance and academic performance of medical students, if any.Methods: An institution based cross-sectional study was conducted in the month of March 2018 among 203 medical students of Tripura Medical College and Dr. B.R.A.M. Teaching Hospital. Probability Proportionate to Sample Size (PPS) was used to determine the number of students required from each semester. Students selected by simple random sampling from each semester were interviewed by a pre-designed, pre-tested interview schedule designed based on Pittsburgh Sleep Quality Index. Data was represented in percentages in tables, charts and Chi square test was applied. P<0.05 was considered statistically significant.Results: Mean age of the medical student was 21.36±1.96 years. Present study showed, 57% students were complaining of disturbed sleep. Students who felt sleepy during daytime (72.4%) were struggling more during exam compared to students not feeling sleepy (51.7%), which was statistically significant. Study revealed, students who got average mark in last semester exam were most affected with disturbed sleep (66.3%) followed by students who got good marks (53.5%) and poor marks (50%).Conclusions: Prevalence of sleep disturbance was very high among medical students. Male students were much more affected compared to female students. Sleep disturbance has also affected academic performance of students.

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