scholarly journals A clinical study of serum lipid profile in benign breast disease in a tertiary care hospital

2019 ◽  
Vol 6 (9) ◽  
pp. 3162 ◽  
Author(s):  
Prabakar M. S. ◽  
Nithyaraj Prakasam ◽  
Reshma S. ◽  
Loganathan K. ◽  
Palani V.

Background: The aim of the study was to evaluate an association of serum lipid profile in women with benign breast disease and to analyze a possible relationship between serum lipid profile and benign breast diseases with emphasis to laboratory findings.Methods: Hospital based study carried out at ACS Medical College, Chennai, during the period of June 2018 to November 2018. 75 women in General Surgery ward/outpatient were included in the study. Subjects included in the study were women of age between 16 to 35 years, provided they fulfilled inclusion and exclusion criteria. History was noted, serum lipid profile was done. Results were noted and analysed.Results: Out of 75 subjects, 21.3% of women with benign breast disease were having elevated serum lipid profile.Conclusions: It is concluded that benign breast disease is associated with altered serum lipid profile namely hyperlipidemia. Therefore, routine screening and treatment of this condition is must among women with benign breast disease by dietary management, use of anti-hyperlipidemic drugs to achieve long lasting cure and to prevent possible future recurrences.

Author(s):  
Mohd. Saeed S. Siddiqui ◽  
Amruta Kailash Loya ◽  
Udaykumar Kanumala ◽  
Jagannath R. Kakade

Background: Dengue is a serious mosquito-borne viral disease which in recent years has become a major international public health concern. Early detection of individuals at risk of developing severe forms of dengue could be possible with the identification of an ideal biomarker, which has been the focus of several research studies. Changes in lipoprotein profile during infection probably are primarily cytokine induced Interactions between microorganisms and lipoproteins occur in viral infections. There have been very few studies that address and elucidate a correlation between dengue fever severity and changes in the lipid profile.Methods: This study was conducted in paediatric patients with dengue infection of age group between 1 to 18 years MGM Medical College and Tertiary Care Hospital of Aurangabad City.Results: There was statistically significant association between TG (mg/dl) level and dengue disease category (DF vs DHS+DSS) among the patients. Overall the combine lipids were significantly predicting dengue disease category (DF, DHS and DSS). Serum lipids (triglycerides, LDL and cholesterol) among the patients significantly predict dengue disease category (DF, DHS and DSS). There was negative correlation between triglycerides level and HDL and hospital Stay which was found to be statistically significant.Conclusions: Reduced serum lipid profile can be used as a cost-effective laboratory investigation prompting a high suspicion of severe dengue infection especially in resource poor setting where serological tests may not be available.


2021 ◽  
pp. 63-64
Author(s):  
Anurag Khare ◽  
Raj Awasthi

Background: Benign breast diseases constitute a heterogeneous group of disorders including developmental abnormality, epithelial and stromal proliferation, inammatory lesions and neoplasm. Benign breast lesions deserve attention because of their high prevalence, their impact on women's life and due to cancerous potential of some histological types. Treatment of BBDS is preservation of breast tissue as far as possible in contrast to traumatizing mutilating surgeries in breast cancers. Objectives:To study pattern and presentation of benign breast lesions over a period of 1 year in a tertiary care hospital of Lucknow, Uttar Pradesh. Material and Methods: This study of 180 cases of histologically diagnosed benign breast lesions was carried out in the Department of Pathology, at tertiary care teaching hospital with attached peripheral hospitals in a metropolitan city of western India from August 2018 to July 2019. Results: Out of 180 benign lesions, 175 (97.2%) were found in females and 05 (2.8%) were found in males. Commonest benign breast lesion was broadenoma (86.1%), followed by brocystic disease (2.2%) and gynaecomastia (2.8%). Conclusion: Fibroadenoma is the most common benign breast disease. Most of the patients presented with painless lump in the breast in upper outer quadrant of the breast. Histopathology plays an important role in the diagnosis of benign breast diseases.


2018 ◽  
Vol 7 (2) ◽  
pp. 50-57
Author(s):  
Bishwa Nath Adhikari ◽  
Pramod Sharma Gautam ◽  
Binod Bekoju ◽  
Sadhana Basnet ◽  
Himlal Bhandari

Introduction: Abnormalities in serum lipid and lipoprotein levels are recognized as major modifiable risk factors for cardiovascular disease and essential hypertension and retinopathy. So this study was conducted to evaluate the role of dyslipidemia on development of retinopathy in hypertensive patients and to establish the association of parameters of serum lipid profile with hypertensive retinopathy. Materials and Methods: A cross-sectional study was conducted in Ophthalmology Department among 135 patients in Nobel Medical College and Teaching Hospital (NoMCTH), Biratnagar who were diagnosed with essential hypertension. Patients having diabetes mellitus, myopia, hazy ocular media and other posterior segment disorders were excluded from the study. The detailed ophthalmic examination was carried out in department of ophthalmology, NoMCTH, Biratnagar and all the study population were investigated for fasting serum lipid profile. Result: Out of 135 patients with essential hypertension, 65.44% had retinopathy and remaining had no signs of retinopathy. Mean age of patients were 60.24 (±15.14) years. Although no gender preponderance was found with retinopathy but this study showed that hypertensive retinopathy increases significantly with increase in age and its incidence increases after the age of 60 years. Conclusion: The duration of hypertension was found to be strongly associated with development of hypertensive retinopathy. The increase in all the lipid profile parameters (Serum TG, TC, and LDL and LDL:HDL) and the obesity were found to be strongly associated with retinopathy in hypertensive patients.


Author(s):  
Hymavathi K. Reddy ◽  
Vineela P. ◽  
Bhargavi M. Chowdary

Background: A comparative study of serum lipid profile and magnesium levels in normal pregnancy versus preeclampsia (PE).Methods: A prospective study done for 2 years (October 2014 to October 2016) in the Department of Obstetrics and Gynecology, Narayana medical college and hospital, a tertiary care centre, Nellore, Andhra Pradesh, India. A sample size of 200 pregnant women, recruited and divided into group A and B. group A being women with PE and group B is normal pregnant women.A10ml of venous blood was collected in the fasting state and serum collected from clotted blood to measure lipid profile, magnesium, Apo lipoprotein A-I and Apo lipoprotein B 100.Serum Lipid profile  measured by enzymatic method using commercially available kit Human (GmbH Germany) using humastar 600 chemistry analyzer (Human GmbH Germany). Serum magnesium measured by dye binding method using commercially available kit Human (GmbH Germany) using Humastar 600 chemistry analyzer (Human GmbH Germany). Serum ApoA-I and ApoB were measured by immune-turbidometry using commercial kits from Spinreact Spain. Urine albumin done by dipstick method.Results: Serum total cholesterol (TC), Triglyceride (TG), low density lipoprotein (LDL), very low-density lipoprotein (VLDL), Apo lipoprotein B 100 (Apo B100) were high and serum Magnesium, high density lipoprotein (HDL) and Apo lipoprotein A1(Apo A1) were low in the study group (group A) compared to controls (group B).Conclusions: Abnormal lipid profile (low HDL and increased TG concentration) and serum hypomagnesaemia may be contributing etiologies of preeclampsia, having good predictive value as a screening procedure for PE in high risk pregnant population.


Author(s):  
Dr. Nanu Ram Jat ◽  
Dr. Ritu Gupta ◽  
Dr. Ayushi Gupta

Only one group was investigated for serum lipid profile in third trimester of pregnancy in which included all PIH patients admitted in labor room in Department of Obstetrics in Jhalawar Medical College and was substantially compared with the normal values of Lipids in women. In this study we investigate the role of lipid profile in PIH. LDL value increase, HDL value decrease, TG value increase and VLDL value increase in PIH patients and also TG : HDL ration increased significantly in PIH patients. Dyslipidemia mediated activation of endothelial cells to placentally derived endothelial disturbing factors like lipid peroxides and trophoblastic components as possible contributors for pathogenesis of PIH. Thus assessment of blood lipids may be helpful in preventions of complications in PIH. Key Words: Bloodlipids, PIH, Dyslipidemia, Triglycerides, Low Density Lipoprotiens, High Density Lipoprotiens.


2013 ◽  
Vol 2 (2) ◽  
pp. 24-29
Author(s):  
Shrawan Kumar Yadav ◽  
Niraj Nepal ◽  
Dilliram Niroula

Journal of Nobel Medical College Vol. 2, No.2 Issue 4 May-October 2013 Page 24-29 DOI: http://dx.doi.org/10.3126/jonmc.v2i2.8801


2017 ◽  
Vol 4 (10) ◽  
pp. 3317
Author(s):  
Anand Kumar Jaiswal ◽  
Rakesh Saxena ◽  
Shesh Kumar

Background: Benign breast disease can be defined to include all those breast diseases which are not malignant. The diagnostic dilemma is for the disease like atypical ductal hyperplasia, mammary intra epithelial neoplasia, ductal carcinoma in situ and lobular carcinoma in situ.Methods: An epidemiological study of 78 patients of benign breast diseases who attend the surgery OPD or admitted as indoor patients in the department of general surgery, B.R.D. Medical College Gorakhpur during a period of one year.Results: Benign breast diseases were most common in third decade (51.28%) following fourth decade (23.07%) of life. Most of the patients belongs to middle (37.1%) and higher (32.5%) socioeconomic status. Fibroadenosis (34.61%) was found to be commonest lesion followed by fibroadenoma (26.92%) and mastitis (24.35%).Conclusions: In our study of benign breast disease, breast pain was the commonest presenting symptom (64.01%) followed by lump in the breast (42.3%). The final diagnosis of benign breast lesion in descending order was fibroadenosis (34.6%), fibroadenoma (26.9%), mastitis (24.4%), duct ectasia (3.8%) and dermatitis of nipple, gynaecomastia 2.56% each. Only one case each (1.2%) of cystosarcoma phyllode, duct papilloma, tuberculosis and galactocele was seen.


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