scholarly journals A comparative study of negative pressure dressing and conventional dressing in lower limb ulcers

2021 ◽  
Author(s):  
Vishal S. Shah ◽  
Narendra K. Prajapati ◽  
Dhruven H. Ponkiya
Keyword(s):  
Wound Healing ◽  
Negative Pressure ◽  
Lower Limb ◽  
Common Disease ◽  
Medical Sciences ◽  
Group A ◽  
Group B ◽  
A Prospective Study ◽  
And Control ◽  
Pressure Dressing

Background: Lower limb ulcer is a common disease among the Indian population with a prevalence of approximately 1% to 2% which is slightly higher in the older population. There are various modalities of treatment with the main aim being early wound healing. This study is done to compare the results of negative pressure dressing and conventional dressing in lower limb ulcers.Methods: This study, done at the Department of Surgery, G. K. General Hospital and Gujarat Adani Institute of Medical Sciences, Bhuj, from October 2017 to September 2018 is a prospective study. A total of 120 patients were randomly divided in two group comprising of 60 patients each. The patients in Group A were treated with negative pressure dressing while those in Group B were treated with conventional dressing. The patients were assessed, in both test and control groups, with parameters like appearance of granulation tissue, bacterial clearance and wound healing.Results: 80% of the patients belonged to the age group of 41-60 years while others were less than 40 years. We observed that in Group A majority of the patients had wound healing in 11-40 days while in Group B majority patients took 31-60 days for their wounds to be healed.Conclusions: We conclude that negative pressure dressing is more efficient as compared to conventional dressing for healing of lower limb ulcers, enabling a shorter hospital stay and early resumption of daily activities to the patient. 

scholarly journals A Comparative Study of Efficacy and Safety Between Tamsulosin and Terazosin in the Treatment of Symptomatic Benign Prostatic Hyperplasia

2016 ◽  
Vol 15 (1) ◽  
pp. 17-21
Author(s):  
Sakhawat Mahmud Khan ◽  
Md Matiar Rahaman Khan ◽  
Shahin Akhter ◽  
Md Mizanur Rahman
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Prostatic Hyperplasia ◽  
Common Disease ◽  
Efficacy And Safety ◽  
College Hospital ◽  
Symptomatic Benign Prostatic Hyperplasia ◽  
Group A ◽  
Group B ◽  
A Prospective Study

Background: Lower urinary tract symptoms suggestive of symptomatic Benign Prostatic Hyperplasia (BPH) are a very common disease in elderly men .The incidence of benign prostatic hyperplasia is age related.Objectives: To compare the efficacy and safety of Tamsulosin and Terazosin in the treatment of symptomatic Benign Prostatic Hyperplasia.Methods: This was a prospective study carried out in the Department of Urology, Chittagong Medial College Hospital, Chittagong, Bangladesh during the period of July to December 2014. Total 40 patients of 45-80 years of age were consequently selected according to inclusion criteria. After completion of baseline clinical evaluation and investigations, participants were divided into two groups, group A and group B. Group A (n=20) was given Terazosin 1mg daily for 3 days at bed time and then 2 mg daily at bed time for 2 months. Group B (n=20) was given Tamsulosin, 0.4 mg per day for 2 months. Efficacy was evaluated of each group after 2 month follow up and lastly a comparison was made between them. The parameters monitored were International Prostate Symptoms Score (IPSS) Maximum urine flow rate (Qmax) and Post Voidal Residual Volume (PVR). Tamsulosin 0.4 mg and Terazosin 2 mg once daily for 8 weeks both are effective in relieving symptoms of BPH but Tamsulosin is superior to Terazosin in improvement of total IPSS (p<0.001) and Qmax (p<0.01) PVR (p<0.01) at the end point.Results: Outcome of parameters at follow up after 2 months. Tamsulosin group showed significant improvement of IPSS (p<0.05) PVR (p<0.001) and Qmax (p<0.001) than Terazosin. The incidence of adverse events by administration of Tamsulosin was less than that by Terazosin.Conclusion: Tamsulosin appears to have more efficacy and safety than Terazosin in symptomatic BPH.Chatt  Shi Hosp Med Coll J; Vol.15 (1); Jan 2016; Page 17-21

scholarly journals A Comparative Study of Efficacy of Povidone Iodine Versus Super Oxidized Solution in Lower Limb Ulcers

2021 ◽  
Vol 10 (37) ◽  
pp. 3220-3224
Author(s):  
Nyna Sindhu Akula ◽  
Navaneeth Krishna ◽  
Sreedhar Sathu
Keyword(s):  
Comparative Study ◽  
Lower Limb ◽  
Povidone Iodine ◽  
Wound Care ◽  
Wound Management ◽  
Average Percentage ◽  
Wound Size ◽  
Group A ◽  
Group B ◽  
A Prospective Study

BACKGROUND Wounds and their management are important in the practice of surgery. Super oxidised solution is a recent concept in wound management. It is an aqueous solution which is electrochemically processed which is non-toxic, non-irrigating and is having a neutral pH. Povidone iodine is the most common topical wound care product used in surgical practice. Both are affordable solutions for the patients. There are very few studies comparing the efficacy. In this study, we wanted to compare the efficacy of super oxidised solution and povidone iodine in the management of lower limb ulcers. METHODS A prospective study was conducted on 100 patients who were randomized into two groups. Group A was treated with super oxidized solution and Group B were treated with povidone iodine. Assessments of wounds were done on various days (1, 3, 5, 7, 9, 12, 15, 18, 21). Various outcomes of data were analysed using statistical analysis. RESULTS The average percentage reduction in wound size on day 21 was 47 % in Group A compared to 24 % in Group B. Early appearance of granulation tissue, disinfection, decrease in wound size, and less duration of hospital stay was achieved in Group A. CONCLUSIONS The results were more favourable towards super oxidised solution than povidone iodine. In this comparative study, super oxidized solution had faster efficacy and wound healing in patients than povidone iodine. KEY WORDS Super Oxidized Solution, Ulcer, Povidone Iodine.

scholarly journals A prospective study of diathermy versus scalpel skin incision in abdominal surgery

2019 ◽  
Vol 6 (10) ◽  
pp. 3554
Author(s):  
Arun Kumar Gupta ◽  
Tejinder Singh Dall ◽  
Darpan Bansal
Keyword(s):  
Prospective Study ◽  
Harmonic Scalpel ◽  
Skin Incision ◽  
Recent Past ◽  
Medical Sciences ◽  
Power Set ◽  
Group A ◽  
Group B ◽  
A Prospective Study ◽  
Time Of Administration

Background: Various methods of skin incision have been identified in the recent past. Traditional skin incisions were made with stainless steel scalpel but recently electrocautery instruments like harmonic scalpel are also in use. With rise of seropositive cases, we aimed to evaluate whether the electrocautery can replace scalpel in operation theater, to avoid unfortunate injury to surgeons with scalpel. So we compared the usefulness of diathermy skin incision vs. scalpel skin incision in general surgical patients.Methods: This prospective study designed to include 120 patients admitted in the Department of General Surgery, Sri Guru Ram Das Institute of Medical Sciences and Research, Vallah, Sri Amritsar and who were undergoing elective abdominal surgical procedures namely cholecystectomy, appendectomy and inguinal hernia repair etc. Patients were randomly allocated into 2 groups of 60 patients each. In Group A, incision were made with electrocautery on cut mode and power set to 60-70. In group B, skin incisions were made with scalpel.Results: No statistical difference was found between group A and group B with regard to time of administration of pain killer injection, seroma formation, discharge being noticed from wound in both groups. Moreover the results were statistically non-significant for vascularity, pigmentation and pliability of wound observed.Conclusions: We concluded that electrocautery can effectively and efficiently replace scalpel in operation theater.

scholarly journals Effectiveness of negative pressure wound therapy for the wound of ileostomy closure: a multicenter, phase II randomized controlled trial

BMC Surgery ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Koichiro Kojima ◽  
Mayu Goto ◽  
Yasuo Nagashima ◽  
Yoko Saito ◽  
Masaya Kawai ◽  
...  
Keyword(s):  
Wound Healing ◽  
Negative Pressure ◽  
Negative Pressure Wound Therapy ◽  
Reduction Rate ◽  
Small Sample ◽  
Ileostomy Closure ◽  
Wound Therapy ◽  
Group A ◽  
American Society ◽  
Group B

Abstract Background The American Society of Surgery and American Society for Surgical Infections issued guidelines for surgical site infections (SSIs) in December 2016. These guidelines recommend a purse-string suture (PSS) for stoma closure as it facilitates granulation and enables open wound drainage. This study investigated the effect of using negative pressure wound therapy (NPWT) along with standard PSS and aimed to determine the optimal period of NPWT use. Methods The patients were divided into three groups as follows: Group A, postoperative wound management alone with gauze exchange as the representative of conventional PSS; Group B, the performed management was similar to that of Group A plus NPWT for 1 week; and Group C, the performed management was similar to that of Group A plus NPWT for 2 weeks. Regarding objective measures, the wound reduction rate was the primary outcome, and the incidence of SSIs, length of hospital stay, and wound healing duration were the secondary outcomes. Results In total, 30 patients (male: 18, female: 12) were enrolled. The average age was 63 (range: 43–84) years. The wound reduction rate was significantly higher in Group B than in Group A on postoperative days (PODs) 7 (66.1 vs. 48.4%, p = 0.049) and 10 (78.6 vs. 58.2%, p = 0.011), whereas no significant difference was observed on POD 14. Compared with Group A, Group C (POD 7: 65.9%, POD 10: 69.2%) showed an increase in the wound reduction rate on POD 7, although the difference was not significant (p = 0.075). SSIs were observed in Groups B (n = 2) and C (n = 2) (20%) but not in Group A (0%). Conclusions The most effective duration of NPWT use for ileostomy closure with PSS in terms of the maximum wound reduction rate was from PODs 3 to 10. However, NPWT did not shorten the wound healing duration. NPWT may reduce the wound size but should be used with precautions for SSIs. The small sample size (30 cases), the use of only one type of NPWT system, and the fact that wound assessment was subjective and not blinded were the limitations of this study. Further studies are needed to confirm our findings. Trial registration: UMIN Clinical Trials Registry; UMIN000032174 (10/04/2018).

Evaluation of autologous and homologous platelet rich plasma as a surgical wound healing promoter in rabbits

2018 ◽  
Author(s):  
Muhammad Shahid Tahir ◽  
Uzma Farid Durrani ◽  
Asim Khalid Mahmood ◽  
Raheela Akhtar ◽  
Rashid Hussain ◽  
...  
Keyword(s):  
Wound Healing ◽  
Platelet Rich Plasma ◽  
Skin Grafting ◽  
Treated Group ◽  
Surgical Wound ◽  
Cosmetic Appearance ◽  
Tissue Proliferation ◽  
Group A ◽  
Group B ◽  
And Control

The present study compared the efficacy of autologous and homologous platelet rich plasma (PRP) as a surgical wound healing promoter in rabbits. Sixteen adult healthy rabbits were divided into two groups i.e. A and B. Group A was treated with autologous platelet rich plasma (APRP) and group B was treated with homologous platelet rich plasma (HPRP). Both groups were operated for skin grafting (auto grafting) at two (PRP treated experimental and control) sites. Clinical evaluation of PRP was performed by using macroscopic (edema, exudation, coloration, temperature, cosmetic appearance and healing status) and microscopic (acute inflammation, fibroblast proliferation and granulation tissue proliferation) parameters. The healing status, coloration and cosmetic appearance of APRP treated group were more satisfactory than HPRP treated group. APRP group also showed less inflammation, edema and more granular tissue proliferation as compare to HPRP group. It was concluded that autologous PRP is an efficient surgical wound healing promoter in rabbits.

scholarly journals Outcome of manual hemorrhoidopexy in the management of hemorrhoids

2014 ◽  
Vol 9 (2) ◽  
pp. 15-19
Author(s):  
Sujit Kumar ◽  
P Kafle ◽  
SJ Shrestha ◽  
S Agrawal ◽  
BN Patowary
Keyword(s):  
Medical Sciences ◽  
Analgesic Requirement ◽  
Conventional Hemorrhoidectomy ◽  
Significant Difference ◽  
Internal Hemorrhoids ◽  
Group A ◽  
Male Patients ◽  
A New Technique ◽  
Group B ◽  
A Prospective Study

Background: Manual hemorrhoidopexy is a new technique of treating second degree hemorrhoids. In contrast to the conventional resectional techniques (Milligan-Morgan), manual hemorrhoidopexy is a novel technique as described by T Carlo. It does not involve excision but plication with fixation of the prolapsing hemorrhoid. Objective: To study the outcome of manual hemorrhoidopexy and to compare manual hemorrhoidopexy with the traditional hemorrhoidectomy. Methods: This is a prospective study conducted over 16 months (January 2012 to April 2013) in the College of Medical Sciences Teaching Hospital (COMS-TH), Bharatpur, Chitwan, Department of Surgery. The patients who presented with third degree internal-hemorrhoids on a random basis, and underwent either conventional hemorrhoidectomy (Group A) or Manual hemorrhoidopexy (Group B) by senior consultant surgeons were included. The patients who had external hemorrhoids in addition to internal were excluded. Preoperative, intraoperative, and postoperative characteristics were evaluated. Results: Twenty five patients with median age group 42.5 years underwent conventional (Milligan-Morgan) hemorrhoidectomy (Group A) and 25 patients with mean age of 40.1 years underwent manual hemorrhoidopexy (Group B). Male patients were predominant in both groups. The patients in group A had more postoperative pain as compared to group B (as assessed by the visual analogue scale and requirement of post-operative analgesic) and this was statistically significant (p<0.001). There was no significant difference among the other post-operative urinary retention. Twelve percent (n=3) patients in group A had post-operative bleeding and only 4% (n=1) in group B which was statistically significant (p<0.001). Mean duration of hospital stay in group A was 2.5 days as compared to 1.5 day in group B. Median follow up in both the study group was 3 (2-4) months. Conclusion: Manual hemorrhoidopexy has comparable outcomes in term of postoperative analgesic requirement, and post operative complications. Journal of College of Medical Sciences-Nepal, 2013, Vol-9, No-2, 15-19 DOI: http://dx.doi.org/10.3126/jcmsn.v9i2.9682

scholarly journals Role of Fetal Serum Prolactin in Pregnancy

2015 ◽  
Vol 3 (2) ◽  
Author(s):  
DR. SAYESHA VIRK ◽  
DR SHIKHA JOSHI ◽  
DR AMRITA BHADAURIA ◽  
DR. C. HARIHARAN
Keyword(s):  
Prolactin Level ◽  
Serum Prolactin ◽  
Medical Sciences ◽  
Serum Prolactin Level ◽  
Cord Serum ◽  
Fetal Serum ◽  
Group A ◽  
Group B ◽  
A Prospective Study

<p>In our study we have tried to to study the comparison of fetal cord serum prolactin level in normal and abnormal pregnancies and correlate the cord serum prolactin level with occurrence of HMD and to establish the fact that If cord serum prolactin is less, then there might be the chances of neonate developing HMD .study was conducted in Department of Obstetrics and Gynaecology, Datta Meghe Institute Of Medical Sciences, Sawangi (Meghe), Wardha (1st September 2005 to 31st August 2007: on 160 randomly selected booked and unbooked women GROUP A 80 women with normal pregnancies GROUP B 80 women with abnormal pregnancies.</p><p><br />In a prospective study umbilical cord serum prolactin level was found to be lower in women with abnormal pregnancy.</p>

CLINICAL OUTCOME AND COST COMPARISON OF CARPAL TUNNEL WOUND CLOSURE WITH MONOCRYL® AND ETHILON®: A PROSPECTIVE STUDY

Hand Surgery ◽  
2013 ◽  
Vol 18 (02) ◽  
pp. 189-192 ◽  
Author(s):  
Anis Dosani ◽  
Sameer K. Khan ◽  
Sheila Gray ◽  
Steve Joseph ◽  
Ian A. Whittaker
Keyword(s):  
Carpal Tunnel ◽  
Wound Closure ◽  
Unit Cost ◽  
Cost Effective ◽  
Cost Comparison ◽  
Absorbable Suture ◽  
Significant Difference ◽  
Group A ◽  
Group B ◽  
A Prospective Study

This prospective non-randomised two-cohort study compares the use of an absorbable suture (Poliglecrapone [Monocryl]: Group A) and a non-absorbable suture (Polyamide [Ethilon]: Group B) in wound closure after elective carpal tunnel decompression. The primary outcome was scar cosmesis as assessed by the Stonybrook Scar Evaluation Scale (SBSES); the financial cost of wound closure was compared as a secondary outocome. All fifty patients completed follow-up. At six weeks, there was no significant difference in the two groups regarding scar tenderness (p = 0.5), although residual swelling was more evident in the absorbable group (p = 0.2). The mean SBSES score at six weeks was 4.72 in Group A, and 4.8 in Group B (p = 0.3). The unit cost per closed wound of Monocryl was three times than Ethilon (p < 0.05). Ethilon is thus cost-effective without compromising the cosmetic outcome, and we recommend using this as the preferred suture for closure of carpal tunnel wounds.

Does laryngopharyngeal reflux affect healing and recovery after tonsillectomy?

2007 ◽  
Vol 122 (6) ◽  
pp. 603-608 ◽  
Author(s):  
S Elwany ◽  
Y A Nour ◽  
E A Magdy
Keyword(s):  
Wound Healing ◽  
Laryngopharyngeal Reflux ◽  
Ph Monitoring ◽  
Control Group ◽  
Study Group ◽  
Pain Scores ◽  
Blinded Study ◽  
Group A ◽  
Group B ◽  
Control Group Group

AbstractIntroduction:Laryngopharyngeal reflux is increasingly being implicated in several otolaryngological disorders.Aims:To study a potential correlation between pre-operative laryngopharyngeal reflux and wound healing and recovery after tonsillectomy, based on subjective and objective findings.Materials and methods:A prospective, blinded study was undertaken, including 60 patients scheduled for tonsillectomy, divided into two equal groups: a study group (group A) with pre-operative laryngopharyngeal reflux documented using ambulatory 24-hour pH monitoring; and a control group (group B) without laryngopharyngeal reflux.Results:Group A had significantly higher pain scores on the seventh and 14th post-operative days (p = 0.022 and p = 0.000, respectively) and took a significantly longer time to return to normal eating (p = 0.013), compared with group B. Group A also showed significantly slower healing on the seventh and 14th post-operative days, as estimated by assessing the grade of post-operative slough formation (p = 0.016 and p = 0.029, respectively). A significant correlation between the number of pharyngeal reflux episodes and the degree of post-operative slough was also found.Conclusions:Laryngopharyngeal reflux can significantly decrease wound healing following tonsillectomy. Therefore, pre-operative recognition and management of this condition is desirable in order to eliminate its negative post-operative effect.

Resorbable Collagen Barrier Impeding the Extrusion of Obturating Material in Primary Molars Undergoing Resorption – A Randomized Clinical Trial

2021 ◽  
Vol 45 (5) ◽  
pp. 312-316
Author(s):  
Mishra Neha Sanjeev ◽  
Harsimran Kaur ◽  
Sandeep Singh Mayall ◽  
Rishika ◽  
Ramakrishna Yeluri
Keyword(s):  
Test Group ◽  
Primary Molars ◽  
Control Group ◽  
Chi Square ◽  
Significance Level ◽  
Significant Difference ◽  
Chi Square Test ◽  
Group A ◽  
Group B ◽  
And Control

Objective: To evaluate the effectiveness of placing a resorbable collagen barrier in impeding the extrusion of obturation material in primary molars undergoing resorption. Study design: All the 94 canals in 47 mandibular molars were allocated to 2 groups- Group ‘A’- 47 canals with collagen barrier (Test group) and Group ‘B’- 47 canals without collagen barrier (Control group) based on randomization protocol. Pulpectomy was performed and obturation of both test and control canals were radiographically assessed. Pearson’s chi – square test was applied to analyze the results. The significance level was predetermined at p &lt; 0.05. Results: Among the test group, 93.6% of the canals showed no extrusion while, 6.4% showed visible extrusion of the material outside the apex. In the control group, 83% showed no extrusion whereas 17% of the canals showed visible extrusion outside the apex. But no significant difference was noted (p&gt;0.05). Conclusion: The placement of resorbable collagen barrier in the apical third of the canal prevented the extrusion of obturating material beyond the apex in resorbing primary molars.

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