scholarly journals Role of Fetal Serum Prolactin in Pregnancy

2015 ◽  
Vol 3 (2) ◽  
Author(s):  
DR. SAYESHA VIRK ◽  
DR SHIKHA JOSHI ◽  
DR AMRITA BHADAURIA ◽  
DR. C. HARIHARAN
Keyword(s):  
Prolactin Level ◽  
Serum Prolactin ◽  
Medical Sciences ◽  
Serum Prolactin Level ◽  
Cord Serum ◽  
Fetal Serum ◽  
Group A ◽  
Group B ◽  
A Prospective Study

<p>In our study we have tried to to study the comparison of fetal cord serum prolactin level in normal and abnormal pregnancies and correlate the cord serum prolactin level with occurrence of HMD and to establish the fact that If cord serum prolactin is less, then there might be the chances of neonate developing HMD .study was conducted in Department of Obstetrics and Gynaecology, Datta Meghe Institute Of Medical Sciences, Sawangi (Meghe), Wardha (1st September 2005 to 31st August 2007: on 160 randomly selected booked and unbooked women GROUP A 80 women with normal pregnancies GROUP B 80 women with abnormal pregnancies.</p><p><br />In a prospective study umbilical cord serum prolactin level was found to be lower in women with abnormal pregnancy.</p>

scholarly journals Prolactin level in umbilical cord blood of newborn and its relation to respiratory distress syndrome

2017 ◽  
Vol 6 (2) ◽  
pp. 433 ◽  
Author(s):  
Namrata V. Padvi ◽  
Hemraj R. Narkhede ◽  
Amol P. Pawar ◽  
Pravin N. Mhatre
Keyword(s):  
Birth Weight ◽  
Cord Blood ◽  
Prolactin Level ◽  
Distress Syndrome ◽  
Normal Pregnancy ◽  
Serum Prolactin ◽  
Serum Prolactin Level ◽  
Maternal Complications ◽  
Group A ◽  
Group B

Background: Production of lower concentrations of prolactin in fetus is considered as one of the major contributor for the development of respiratory distress syndrome (RDS) in newborns considerably in pregnants with maternal complications. Hence the present study was conducted with the objective to measure the serum level of cord blood prolactin in normal pregnancy and in pregnancy with maternal complications and its association with development of RDS in newborn.Methods: In this prospective study of 100 women, 28 with normal pregnancy (Group A) and 72 with abnormal pregnancies (Group B) were included in the study. Umbilical cord blood was collected and serum prolactin level was estimated using radio-immuno assay. The obtained values were correlated with prevalence of RDS in neonates and maternal complications.Results: The average age of pregnant women participated in Group A was 26 years and Group B was 27 years. In Group A 2 babies with birth weight of 2001-3000 gm had a cord serum prolactin level of 216±137.8 ng/mL developed RDS. In Group B the level of prolactin was 285±276 and 326±132 ng/mL in 4 RDS babies with birth weight of <1000 gm and 1000-2000 gm respectively. It was observed that cord serum prolactin levels had no correlation with the mode of delivery, sex of newborn, steroid therapy. In Group A, 2 neonates developed RDS which were of gestational age between 32-35 weeks with mean prolactin level of 216 ng/ml, while in Group B, 1 neonate with gestational age less than 32 weeks and mean prolactin level of 480 and 4 neonates of 32-35 weeks with mean prolactin level of 266 ng/mL developed RDS. Out of 27 mothers with complications of PIH, 3 developed RDS. 1 case each from IUGR and twins developed RDS respectively.Conclusions: The risk of RDS is less in newborn with high prolactin level than in newborns with low prolactin levels. So prolactin might have a role in fetal lung maturation.

“A PROSPECTIVE STUDY: ROLE OF TRACTION ON FOLEY’S CATHETER IN TURP PATIENTS”

2021 ◽  
pp. 27-29
Author(s):  
Prashant Lavania ◽  
Ankush Gupta ◽  
Rahul Chaudhary
Keyword(s):  
Blood Loss ◽  
Early Discharge ◽  
Common Condition ◽  
Medical College ◽  
Duration Of Hospital Stay ◽  
Group A ◽  
Foley’S Catheter ◽  
Group B ◽  
A Prospective Study

INTRODUCTION: Benign prostatic hyperplasia (BPH) is the most common condition affecting men those are 50 years of age and above.TURP is still the widely used technique for management of BPH. TURPwith advent of newer technologies in diathermy and visual scope, has turned into a relatively safe one. AIM:To study role of catheter traction on blood loss and complications in patients with TURP. MATERIALS AND METHODS: This study was done among patients of BPH admitted in the Department of Surgery at S.N. Medical College, Agra during the period from January 2019 to February 2020. Total 60 cases were enrolled in the study and divided into two groups. Group A(30 patients) with traction on catheter after TURPand Group B(30 patients) without traction on catheter. DISCUSSION: Blood loss and irrigation uid was signicantly less in the group with traction on foley's catheter. Duration of hospital stay and complications were also lesser in group with traction. CONCLUSION: Traction on foley's catheter post TURP is effective in managing BPH with the merits of higher safety due to less blood loss and early discharge.

scholarly journals A prospective study of diathermy versus scalpel skin incision in abdominal surgery

2019 ◽  
Vol 6 (10) ◽  
pp. 3554
Author(s):  
Arun Kumar Gupta ◽  
Tejinder Singh Dall ◽  
Darpan Bansal
Keyword(s):  
Prospective Study ◽  
Harmonic Scalpel ◽  
Skin Incision ◽  
Recent Past ◽  
Medical Sciences ◽  
Power Set ◽  
Group A ◽  
Group B ◽  
A Prospective Study ◽  
Time Of Administration

Background: Various methods of skin incision have been identified in the recent past. Traditional skin incisions were made with stainless steel scalpel but recently electrocautery instruments like harmonic scalpel are also in use. With rise of seropositive cases, we aimed to evaluate whether the electrocautery can replace scalpel in operation theater, to avoid unfortunate injury to surgeons with scalpel. So we compared the usefulness of diathermy skin incision vs. scalpel skin incision in general surgical patients.Methods: This prospective study designed to include 120 patients admitted in the Department of General Surgery, Sri Guru Ram Das Institute of Medical Sciences and Research, Vallah, Sri Amritsar and who were undergoing elective abdominal surgical procedures namely cholecystectomy, appendectomy and inguinal hernia repair etc. Patients were randomly allocated into 2 groups of 60 patients each. In Group A, incision were made with electrocautery on cut mode and power set to 60-70. In group B, skin incisions were made with scalpel.Results: No statistical difference was found between group A and group B with regard to time of administration of pain killer injection, seroma formation, discharge being noticed from wound in both groups. Moreover the results were statistically non-significant for vascularity, pigmentation and pliability of wound observed.Conclusions: We concluded that electrocautery can effectively and efficiently replace scalpel in operation theater.

scholarly journals Role of hydrocortisone and pheniramine as prophylaxis against adverse drug reaction to snake antivenom

2021 ◽  
Vol 8 (11) ◽  
pp. 1714
Author(s):  
Arjimand Yaqoob ◽  
Showkat A. Mufti ◽  
Sharika Ashraf
Keyword(s):  
Adverse Reaction ◽  
Adverse Reactions ◽  
Primary Treatment ◽  
Medical Sciences ◽  
Snake Envenomation ◽  
Group A ◽  
Prospective Comparative Study ◽  
Pre Treatment ◽  
Group B

Background: Antivenom remains the primary treatment for any patient with serious snake envenomation and in most patients should be used whenever indicated. Reactions to most antivenom preparations are common. Evidence does not support routine pre-treatment with either antihistamines or corticosteroids.Methods: This hospital based retrospective and prospective comparative study was conducted at Sher-i-Kashmir Institute of Medical Sciences, Srinagar. In our study 108 patients were studied. Patients in group A received premedication with injection hydrocortisone 100 mg and injection pheniramine 25 mg intravenous (IV) stat before anti-snake venom (ASV). Patients in group B did not receive any premedication. Adverse reactions to ASV was compared in two groups.Results: Out of 108 patients, 105 (97.22%) required ASV. Fifty nine were retrospective cases (group A) who had received premedication with hydrocortisone and pheniramine. Forty six patients were studied prospectively, who received ASV (group B) with no premedication. In group A, no patient developed adverse reaction to ASV. 3 patients (6.52%) in group B developed adverse reaction to ASV.Conclusions: Premedication with hydrocortisone and pheniramine do not prevent adverse reactions to ASV significantly. Adverse reactions to ASV were low in our study to comment fully on role of premedication to prevent these reactions.

scholarly journals Outcome of manual hemorrhoidopexy in the management of hemorrhoids

2014 ◽  
Vol 9 (2) ◽  
pp. 15-19
Author(s):  
Sujit Kumar ◽  
P Kafle ◽  
SJ Shrestha ◽  
S Agrawal ◽  
BN Patowary
Keyword(s):  
Medical Sciences ◽  
Analgesic Requirement ◽  
Conventional Hemorrhoidectomy ◽  
Significant Difference ◽  
Internal Hemorrhoids ◽  
Group A ◽  
Male Patients ◽  
A New Technique ◽  
Group B ◽  
A Prospective Study

Background: Manual hemorrhoidopexy is a new technique of treating second degree hemorrhoids. In contrast to the conventional resectional techniques (Milligan-Morgan), manual hemorrhoidopexy is a novel technique as described by T Carlo. It does not involve excision but plication with fixation of the prolapsing hemorrhoid. Objective: To study the outcome of manual hemorrhoidopexy and to compare manual hemorrhoidopexy with the traditional hemorrhoidectomy. Methods: This is a prospective study conducted over 16 months (January 2012 to April 2013) in the College of Medical Sciences Teaching Hospital (COMS-TH), Bharatpur, Chitwan, Department of Surgery. The patients who presented with third degree internal-hemorrhoids on a random basis, and underwent either conventional hemorrhoidectomy (Group A) or Manual hemorrhoidopexy (Group B) by senior consultant surgeons were included. The patients who had external hemorrhoids in addition to internal were excluded. Preoperative, intraoperative, and postoperative characteristics were evaluated. Results: Twenty five patients with median age group 42.5 years underwent conventional (Milligan-Morgan) hemorrhoidectomy (Group A) and 25 patients with mean age of 40.1 years underwent manual hemorrhoidopexy (Group B). Male patients were predominant in both groups. The patients in group A had more postoperative pain as compared to group B (as assessed by the visual analogue scale and requirement of post-operative analgesic) and this was statistically significant (p<0.001). There was no significant difference among the other post-operative urinary retention. Twelve percent (n=3) patients in group A had post-operative bleeding and only 4% (n=1) in group B which was statistically significant (p<0.001). Mean duration of hospital stay in group A was 2.5 days as compared to 1.5 day in group B. Median follow up in both the study group was 3 (2-4) months. Conclusion: Manual hemorrhoidopexy has comparable outcomes in term of postoperative analgesic requirement, and post operative complications. Journal of College of Medical Sciences-Nepal, 2013, Vol-9, No-2, 15-19 DOI: http://dx.doi.org/10.3126/jcmsn.v9i2.9682

scholarly journals Is there any role of post operative antibiotics in reducing secondary haemorrhage after tonsillectomy

2012 ◽  
Vol 18 (2) ◽  
pp. 166-170
Author(s):  
Mohammad Shah Kamal ◽  
Rubina Farzana ◽  
Ahmed Tariq ◽  
Abu Hena Mohammad Parvez Humayun
Keyword(s):  
Intervention Group ◽  
Control Group ◽  
Antibiotic Group ◽  
Group A ◽  
Secondary Haemorrhage ◽  
Group B ◽  
A Prospective Study ◽  
Haemorrhage Rate

Objective: To compare with and without the antibiotic therapy in reducing post-tonsillectomy secondary haemorrhage.Method: A prospective study was conducted at Shaheed Shamsuddin Ahmed Hospital, Sylhet from April 2010 to April 2012. 170 patients who underwent tonsillectomy divided into two groups randomly each consisting of 85 patients. In group A (intervention group) - antibiotic was given post-operatively, while in group B (control group) - no antibiotic was given. Postoperative follow-up was done till the tonsillar fossa healed.Results: Among 170 patients 61.18% were female and 38.82% were male, mean age was 21.58 years. One patient from antibiotic group had secondary haemorrhage (1.18%), while no haemorrhage was observed in non- antibiotic group. Secondary haemorrhage rate was 0.59% in total study population.Conclusion: The study showed that antibiotic did not have any significant role in reducing the post-tonsillectomy secondary haemorrhage DOI: http://dx.doi.org/10.3329/bjo.v18i2.12009 Bangladesh J Otorhinolaryngol 2012; 18(2): 166-170

scholarly journals A comparative study of negative pressure dressing and conventional dressing in lower limb ulcers

2021 ◽  
Author(s):  
Vishal S. Shah ◽  
Narendra K. Prajapati ◽  
Dhruven H. Ponkiya
Keyword(s):  
Wound Healing ◽  
Negative Pressure ◽  
Lower Limb ◽  
Common Disease ◽  
Medical Sciences ◽  
Group A ◽  
Group B ◽  
A Prospective Study ◽  
And Control ◽  
Pressure Dressing

Background: Lower limb ulcer is a common disease among the Indian population with a prevalence of approximately 1% to 2% which is slightly higher in the older population. There are various modalities of treatment with the main aim being early wound healing. This study is done to compare the results of negative pressure dressing and conventional dressing in lower limb ulcers.Methods: This study, done at the Department of Surgery, G. K. General Hospital and Gujarat Adani Institute of Medical Sciences, Bhuj, from October 2017 to September 2018 is a prospective study. A total of 120 patients were randomly divided in two group comprising of 60 patients each. The patients in Group A were treated with negative pressure dressing while those in Group B were treated with conventional dressing. The patients were assessed, in both test and control groups, with parameters like appearance of granulation tissue, bacterial clearance and wound healing.Results: 80% of the patients belonged to the age group of 41-60 years while others were less than 40 years. We observed that in Group A majority of the patients had wound healing in 11-40 days while in Group B majority patients took 31-60 days for their wounds to be healed.Conclusions: We conclude that negative pressure dressing is more efficient as compared to conventional dressing for healing of lower limb ulcers, enabling a shorter hospital stay and early resumption of daily activities to the patient. 

SERUM PROLACTINE LEVEL IN PATIENTS OF PSORIASIS VULGARIS AND ITS CORRELATION WITH DISEASE SEVERITY: A CASE-CONTROL STUDY

2019 ◽  
Vol 3 (6) ◽  
Author(s):  
Pawan Kumar Saini ◽  
Devendra Yadav ◽  
Rozy Badyal ◽  
Suresh Jain ◽  
Arti Singh ◽  
...  
Keyword(s):  
Disease Severity ◽  
Prolactin Level ◽  
Case Control Study ◽  
Statistical Significance ◽  
Case Control ◽  
Serum Prolactin ◽  
P Value ◽  
Serum Prolactin Level ◽  
R Value ◽  
Control Study

Background: Psoriasis is an autoimmune chronic inflammatory disorder affecting the skin mediated by T-lymphocytes resulting in production of cytokines which cause hyperproliferation of keratinocytes.  Several factors and hormones like Prolactin have an action similar to these cytokines in promoting the multiplication of keratinocytes and other cells like lymphocytes and epithelial cells may have a role on the etiopathogenesis of psoriasis. Aim:-The aim of study is to compare the serum Prolactin levels in patients of psoriasis with a control group. Setting and study design: This is a case-control study conducted in the department of Dermatology, Venereology and Leprosy GMC, Kota over a period of 1year from July 2017 to June 2018 Material and method: The study included 100 cases of psoriasis (60 males and 40 females) and 100 controls similar for age and sex. Serum Prolactin levels were measured by ECLIA and results were obtained. Statistical analysis: Mean and standard deviation were calculated for each variable. Statistical significance of the results was analyzed using correlation analysis (Pearson correlation coefficient) and independent samples t-test. Statistical significance was assumed at p value<0.05. Result: Serum Prolactin level was significantly higher in cases of psoriasis compared to controls (p-value <0.001). PASI score and serum Prolactin levels were found to have a positive correlation (r value = 0.337; p-value: 0.001). No significant  correlation was found between serum levels of Prolactin and duration of disease r value= -0.034, P value =0.733). Serum Prolactin level was higher in male patients compared to females patients. Conclusion:- High serum Prolactin may be a biological marker of disease severity in psoriasis and may have a role in the pathogenesis of psoriasis. Further studies with large sample size are required to confirm this hypothesis.

The Role of Vitamin B6 in Reducing Serum Prolactin in Comparison to Cabergoline

2019 ◽  
Vol 10 (01) ◽  
Author(s):  
Suha J. Witwit
Keyword(s):  
Prolactin Level ◽  
Vitamin B6 ◽  
Reproductive Age ◽  
Serum Prolactin ◽  
Polycystic Ovaries ◽  
Endocrine Disorder ◽  
Hypothalamic Pituitary Axis

Hyperprolactinemia is a common endocrine disorder of hypothalamic-pituitary axis. It affect about 4-17% of women in reproductive age and about 3-10% of patients with polycystic ovaries. Vitamin B6 is an effective prolactin inhibitor that is extremely cheap and safe.it exerts hypothalamic dopaminergic effect which causes a significant reduction in prolactin level. The aim of the study is To evaluate the effectiveness of vitamin B6 in reducing serum prolactin in Hyperprolactinemic patient. Compare this effect to that of cabergoline.

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