scholarly journals Incidence and risk factors for retinopathy of prematurity at a medical college hospital in rural Tamil Nadu, India

2020 ◽  
Vol 7 (11) ◽  
pp. 2119
Author(s):  
Sengodi Elumalai ◽  
Rajasekaran Kathavarayan ◽  
Venkatesh Govindasamy
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Blood Transfusion ◽  
Retinopathy Of Prematurity ◽  
Tamil Nadu ◽  
Care Center ◽  
Tertiary Care ◽  
Significant Risk ◽  
College Hospital

Background: The objective of the research was to evaluate the incidence of retinopathy of prematurity (ROP), association of prenatal and postnatal risk factors, pattern of ROP and treatment outcomes among infants admitted to neonatal intensive care unit (NICU) of tertiary care center located in Thiruvannamalai, Tamil Nadu.Methods: A retrospective study done in all infants admitted between April 2019 and March 2020 who met the criteria for ROP screening with gestational age (GA) less than or equal to 36 weeks or birth weight less than 2000 grams or with GA more than 36 weeks and birth weight more than 2000 gram with significant risk factors like intrauterine growth restriction, respiratory distress syndrome, sepsis, long term oxygen use, phototherapy, blood transfusion and maternal anemia. Treatment was offered to infants with stage 3 ROP and stage 2 in zone 2 with or without plus disease. Qualified infants were treated with argon laser photocoagulation within 72 hours of diagnosis. They were followed until the disease was successfully treated.Results: Out of total 3121 neonates, 717 neonates met the screening criteria. Incidence of ROP was found to be 33% (n=237). 46.4% (n=110) of ROP belongs to 32-36 weeks GA. 42.6% (n=101) of ROP belongs to 1500-2000 gm birth weight.Conclusions: Incidence of ROP is quite high in high risk neonates in our unit. Significant risk factors are long term oxygen use, blood transfusion and sepsis.

scholarly journals Incidence and risk factors of retinopathy of prematurity in Goa, India: a report from tertiary care centre

2019 ◽  
Vol 6 (3) ◽  
pp. 1228
Author(s):  
Sarvesh Kossambe ◽  
Shilpa Joglekar ◽  
Annely D'lima ◽  
M. P. Silveira
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Retinopathy Of Prematurity ◽  
Neonatal Intensive Care ◽  
Laser Photocoagulation ◽  
Very Low Birth Weight ◽  
Care Center ◽  
Tertiary Care ◽  
Preterm Neonates ◽  
Tertiary Care Centre

Background: To report the incidence and risk factors leading to the development of retinopathy of prematurity (ROP) from a tertiary care center in the western Indian state of Goa, India.Methods: This was a prospective observational study carried out in a level II neonatal intensive care unit (NICU) for a period of 18 months. Babies born at < 34 weeks’ gestation and having a birth weight of <1500gm were screened for ROP and laser photocoagulation was done for those who developed threshold ROP. Group differences between any ROP and threshold ROP were analysed using the chi-square test.Results: Out of the 244 preterm neonates screened, 37 developed ROP (15.16%), and 14 out of them (5.73%) developed threshold ROP requiring laser photocoagulation. Very low birth weight, prematurity, apnea, anemia, sepsis, respiratory distress syndrome, bronchopulmonary dysplasia, blood transfusions, exchange transfusions and days taken to reach full enteral feeds and regain birth weight were significantly associated with the development of ROP.Conclusions: This is the first report of ROP from Goa where less than 1 in 5 babies developed ROP. This is similar to that reported across the rest of the country. Judicious oxygen use, ventilation strategies, transfusions guidelines, control of sepsis, early enteral feeds and adequate nutrition may help prevent the development of ROP in the future.

scholarly journals Retinopathy of prematurity: Postnatal weight gain and risk factors profile; a hospital-based study from a tertiary care center

2021 ◽  
Vol 8 (9) ◽  
pp. 324-328
Author(s):  
Pooja Subramanya ◽  
G C M Pradeep ◽  
M Sharanabasavesh ◽  
M V Krithika
Keyword(s):  
Risk Factors ◽  
Weight Gain ◽  
Birth Weight ◽  
Retinopathy Of Prematurity ◽  
Care Center ◽  
Tertiary Care ◽  
Preterm Neonates ◽  
Tertiary Care Center ◽  
Significant Difference ◽  
Postnatal Weight Gain

Background: Premature infants often develop blindness in one or both eyes due to disparity in retinal growth. This condition is termed as retinopathy of prematurity (ROP). Aim: The aim of the study is to study the postnatal weight gain pattern of preterm infants (Age < 32 weeks) and risk factors of ROP in a tertiary care center and to validate the lower birth weight and gestational age (GA) for ROP. Methods: Hospital-based study on 110 preterm neonates admitted in the neonatal intensive care unit (NICU) who fulfilled the criteria for ROP screening. On screening, 55 neonates were identified to have ROP and 55 neonates identified to have no ROP. The profiles of ROP and risk factors were documented according to the International Classification for ROP recommendations. The data were analyzed for GA, birth weight, and risk factors predisposing to ROP. Results: A total of 110 preterm neonates were screened, out of which, 55 had ROP. The mean GA (P = 0.002), Apnea (P = 0.001), ventilation (P = 0.001), and surfactant (P = 0.001) were observed a significant difference. Further, a significant difference in weight gain pattern in the two groups (P < 0.05) was also observed. The group without ROP had a better weight gain pattern than the group with ROP. Conclusion: Our study revealed prematurity, low birth weight, and birth weight increasing patterns were found to be strong predictors of ROP. GA, apnea, ventilation, and surfactant were found to be statistically significant factors associated with ROP.

scholarly journals A retrospective study on the risk factors for retinopathy of prematurity in NICU of tertiary care hospital

2018 ◽  
Vol 5 (4) ◽  
pp. 1447
Author(s):  
Sundar K. C. ◽  
Devi Meenakshi K. ◽  
Aruna B. Patil
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Birth Weight ◽  
Retinopathy Of Prematurity ◽  
Oxygen Therapy ◽  
Tertiary Care ◽  
Care Hospital ◽  
College Hospital ◽  
Medical College ◽  
The Mean

Background: Retinopathy of prematurity (ROP) affects developing retinal vasculature in premature infants. The risk factors for ROP are prematurity, low birth weight, oxygenation, respiratory distress, infection and frequent blood transfusion. Identification of risk factors leading to ROP may help in planning preventive strategies.Methods: A retrospective analysis of records of preterm babies less than 34 weeks of gestation or birth weight less than 1750 grams and between 34 -36 weeks gestation or 1750-2000 grams birth weight associated with risk factors for ROP admitted to NICU of Kilpauk Medical college hospital from August 2015 to July 2016 were evaluated.Results: Out of a total of 166 babies who were screened for ROP, 37 babies were detected to have ROP (22.3 %). Of these 20 (54%) were female and 17 (46%) were male. The mean birth weight of babies with ROP identified in our study was 1480 grams. The mean gestational age of babies with ROP was 32 weeks. By logistic regression analysis for mode of oxygen therapy as a risk factor for ROP it was found that prongs alone showed the strong risk factor towards ROP which was statistically significant. Sepsis, transfusion and shock requiring inotropes individually and statistical significantly contributed to the risk of ROP.Conclusions: ROP was more common in babies <34 weeks. Sepsis, transfusion and shock requiring inotropes significantly contributed to the risk of ROP. Analysis of the mode of oxygen therapy showed that use of prongs significantly increased the risk of ROP.

scholarly journals A prospective study to determine the incidence of retinopathy of prematurity at a tertiary care centre in Western Rajasthan and delineate its risk factors

2017 ◽  
Vol 4 (4) ◽  
pp. 1193 ◽  
Author(s):  
Anoop Mantri ◽  
Mohan Makwana ◽  
Vishnu Goyal ◽  
Vikas Payal ◽  
Harish Mourya ◽  
...  
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Retinopathy Of Prematurity ◽  
Oxygen Therapy ◽  
Tertiary Care ◽  
Significant Risk ◽  
Medical College ◽  
Incidence Studies ◽  
Wide Range

Background: Retinopathy of Prematurity (ROP) is one of the most common causes of preventable blindness in children. Recent advances in the neonatology have increased preterm survival and so has the ROP incidence. Studies all over the world and across the country have shown a wide range for incidence of ROP and so it is difficult to gauge the exact incidence, especially in our region.Methods: This prospective observational study was conducted in neonatal units of the Department of Paediatrics, Dr. S. N. Medical College, Jodhpur for a duration of six months. All newborns delivered in hospitals associated with Dr S. N. Medical College with gestation age at birth <34weeks and 34-36weeks associated with risk factors subjected to ROP screening by indirect ophthalmoscope by a trained ophthalmologist. Neonates with congenital cataract, hazy cornea, abnormal anterior chamber and those who expired or lost to follow up before sufficient examination could be done were excluded.Results: Out of 250 newborns screened, 34 (13.6%) were found positive for ROP and out of these 34, 18 (52.94%) had stage I, 11 (32.35%) had stage II, 5 (14.7%) had stage III and none for stage IV and V. Prolonged oxygen therapy, low birth weight, apnoea and sepsis were found to be significant risk factor (p<0.05) with the relative risk of 12.49, 3.71, 3.03 and 1.91 respectively.Conclusions: ROP is a preventable cause of blindness in children. Thus, its screening is indispensable and it has to be intensified in presence of risk factors such as prolonged oxygen therapy, low birth weight, apnoea and sepsis. 

scholarly journals Retinopathy of Prematurity in A Tertiary Care Hospital in Eastern Nepal

2008 ◽  
Vol 47 (169) ◽  
Author(s):  
Srijana Adhikari ◽  
B P Badhu ◽  
N K Bhatta ◽  
R S Rajbhandari ◽  
B K Kalakheti
Keyword(s):  
Risk Factors ◽  
Intensive Care ◽  
Birth Weight ◽  
Gestational Age ◽  
Retinopathy Of Prematurity ◽  
Neonatal Intensive Care ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Screening Criteria

World Health Organization’s Vision 2020 program has recognized Retinopathy of Prematurity(ROP) as an important cause of childhood blindness in industrialized and developing countries. Inthe last few years, it has been identifi ed in many under developed countries as well, as a result ofimproved neonatal intensive care. In Nepal, ROP screening is carried out in a few tertiary hospitalsbut there is no published data on this disease. The purpose of this study was to fi nd out the incidence,severity and risk factors of ROP among infants screened in a tertiary care hospital in the EasternRegion of Nepal.A prospective cohort study was carried out in neonates with gestational age of 34 weeks or less and,or birth weight of 1700 gm or less born over the period of one year. Dilated fundus examination ofall babies was done by indirect ophthalmoscopy between 2-4 weeks after birth and followed up tillthe retinal vascularization was complete. Classifi cation of ROP was done according to internationalclassifi cation (ICROP). Maternal and neonatal risk factors were also noted.A total of 55 babies fulfi lled the screening criteria. ROP was present in 25.45% (n=14) of the babies.Threshold disease was noted in 5.45% (n=3) of the babies screened. Low birth weight (p<0.01)and low gestational age (p<0.01) was signifi cantly associated with the incidence of ROP. Oxygensupplementation (p=<0.01) was an independent risk factor.ROP screening should be performed in all preterm low birth weight infants where there is availabilityof good neonatal intensive care units. The examination should be intensifi ed in those having riskfactors like oxygen. Further studies in the other tertiary care hospitals in Nepal would help toestablish the screening criteria for Nepalese infants.Key words: Retinopathy of prematurity, Eastern Nepal, screening

Comparison of incidences and indications of multi primary caesarean with primi caesarean mothers in a tertiary care teaching hospital

2017 ◽  
Vol 6 (10) ◽  
pp. 4263
Author(s):  
M. Sujatha Alagesan ◽  
M. Meena
Keyword(s):  
Birth Weight ◽  
Caesarean Section ◽  
Teaching Hospital ◽  
Tamil Nadu ◽  
Caesarean Section Rate ◽  
Tertiary Care ◽  
Foetal Distress ◽  
College Hospital ◽  
Medical College ◽  
Clinical Profiles

Background: The incidences and indications of caesarean sections between the primary caesarean multies and caesarean primies were comparable in respect of their demographical and clinical variables of mothers and their foetal outcomes. Aim and objective of the study was to analyze the incidences and indications of primary caesarean multies and caesarean primies. To compare the incidences and indications of mothers between the primary caesarean multies and caesarean primies. To compare the demographic and clinical profiles of the mothers and babies.Methods: During January to June 2016 total of 3583 deliveries were conducted in Tiruneleli Medical College Hospital, Tamil Nadu, India. Among them 89 and 1168 were primary caesarean multies and caesarean primies respectively. They had been compared according to the objectives.Results: The caesarean incidences were 62.5% among the primies and 4.8% among the multies as Primary. The primary caesarean incidences among the multies were statistically significantly lesser in the 15-24 ages than the primi (P<0.05). 25-29 age bracket the incidences were not differed significantly (P>0.05). After 30 years of age, the incidences were statistically significantly increased among the multies (P<0.05). The birth weight of babies did not show any statistically significant indications between the two groups (P>0.05). The indications of Foetal distress, Severe Oligo hydration and others did not show any statistically significantly difference between the groups (P>0.05). Mal presentation and Ante Partum hemorrhage were significantly more among the multies than primies (p<0.05) and Failed indication and CPD were the significantly lesser indication than the primies (P<0.05).Conclusions: Without reducing the caesarean section rate in primi we cannot bring down the overall caesarean rate of delivery.

scholarly journals Anemia in relation to severity of retinopathy of prematurity in preterm babies born in tertiary care centre in South India

2020 ◽  
Vol 7 (10) ◽  
pp. 2005
Author(s):  
Hrishikesh S. Pai ◽  
Rojo Joy ◽  
Varghese Cherian ◽  
Preethy Peter
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Bronchopulmonary Dysplasia ◽  
Gestational Age ◽  
Retinopathy Of Prematurity ◽  
Tertiary Care ◽  
Oxygen Requirement ◽  
Tertiary Care Centre ◽  
Potential Risk Factors ◽  
Preterm Babies

Background: Retinopathy of prematurity (ROP) is a vaso proliferative disorder of retina among preterm infants. Significant cause of blindness in children with increased survival of premature infants with improved neonatal care. Potential risk factors for development of ROP include low gestational age, low birth weight, bronchopulmonary dysplasia, sepsis, acidosis, oxygen therapy. Anemia as a cause for retinopathy of prematurity has been postulated but there are very few studies addressed the effect of anemia on incidence and severity of ROP. The objective of this study was to determine the effect of anemia on incidence and severity of retinopathy of prematurity and to determine other factors associated with development of retinopathy of prematurity.Methods: Retrospective descriptive study of 120 babies born premature less than 34 weeks for the development of Retinopathy of prematurity and its severity and for associated conditions. All babies screened for retinopathy of prematurity at 3 weeks of age and further followed up for progression of ROP. Factors analysed included hemoglobin levels at 3 weeks of life, number of blood transfusions, days on ventilator, gestational age, birth weight, duration of oxygen requirement, bronchopulmonary dysplasia for the development of retinopathy of prematurity. Findings described in simple descriptive manner.Results: Anemia and increased requirement for blood transfusion are associated with higher incidence and severity of ROP. Low gestational age, birth weight, prolonged oxygen requirement, intraventricular hemorrhage (IVH), sepsis are other risk factors.Conclusions: It is significant to screen preterm babies for ROP and to anticipate in the background of these risk factors. Minimise oxygen duration and blood loss for sampling to prevent anemia and reduce transfusions.

TO STUDY THE INCIDENCE AND RISK FACTORS OF RETINOPATHY OF PREMATURITY IN A TERTIARY CARE HOSPITAL IN NORTHERN INDIA

2021 ◽  
pp. 48-50
Author(s):  
Kajaldeep Kaur ◽  
Gursharn Singh
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Gestational Age ◽  
Retinopathy Of Prematurity ◽  
Neonatal Intensive Care ◽  
Tertiary Care ◽  
Preterm Neonates ◽  
Care Hospital ◽  
Northern India ◽  
Retinal Examination

BACKGROUND: Retinopathy of prematurity (ROP) is a multifactorial retinal vaso-proliferative disorder which remains a leading cause of childhood blindness worldwide despite improvements in neonatal care and management guidelines. This study was conducted to determine the incidence of ROP among preterm neonates and to determine the risk factors. METHODS: All preterm infants with birth weight <1750 gm and gestation <34 weeks were screened for ROP at 4 weeks of birth for rst screening. Prenatal and postnatal risk factors, neonatal problems, treatment given, procedures and interventions done during stay in neonatal intensive care unit were recorded as per the proforma. The data from the study was systematically collected, compiled and statistically analyzed with SPSS Statistics-26 version to draw relevant conclusions. RESULTS: The incidence of ROP in 89 infants who were screened was 44%. The mean gestational age of babies with ROP was 32 weeks. In our study, pneumonia, apnea, sepsis, thrombocytopenia, NEC, shock, acidosis, IVH, BPD, the use of Bubble CPAP, Venti-CPAP and mechanical ventilator, the vasopressor use and blood transfusion were signicant risk factors. CONCLUSIONS: The incidence of ROP was signicantly higher in babies <34 weeks. It was observed in our that lower the birth weight and lower the gestational age, higher is the risk for the development of ROP. Careful and timed retinal examination of all at risk infants will minimize the development of ROP and later on blindness.

PREVALENCE, RISK FACTORS AND TREATMENT OUTCOMES IN NEONATES WITH RETINOPATHY OF PREMATURITY (ROP) WITH BIRTH WEIGHT <1750 GRAMS AND ≥ 1750 GRAMS

2021 ◽  
pp. 56-58
Author(s):  
Monisha SP ◽  
Prempal Kaur ◽  
Karamjit Singh ◽  
Ashwani Kumar ◽  
Upasna Ajmani
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Treatment Outcomes ◽  
Retinopathy Of Prematurity ◽  
Very Low Birth Weight ◽  
Tertiary Care ◽  
High Concentration ◽  
Tertiary Care Centre ◽  
Northern India ◽  
Oxygen Administration

Retinopathy of prematurity (ROP) is one of the major cause of the preventable childhood blindness worldwide. One year prospective interventional study was conducted in a tertiary care centre in Northern India. All neonates with birth weight ≤ 2000 grams with gestational age ≤35 weeks were screened for ROP and divided into two groups, infants with birth weight <1750 grams (Group A) and ≥1750 grams (Group B). Prevalence of ROP, risk factors and laser treatment outcomes were compared between two groups. Of 191 neonates screened, 61(31.93%) developed ROP, out of which Infants with very low birth weight were at signicantly higher risk of developing severe ROP requiring treatment. In addition, high concentration and uctuating oxygen administration, sepsis, shock, intravenous uids >10 days were observed to be statistically signicant risk factors in infants <1750 grams. Timely screening and early treatment of threshold ROP results in desirable structural and functional outcome.

TO STUDY THE CONSEQUENCES OF TEENAGE PREGNANCY- MATERNAL AND PERINATAL OUTCOME IN TERTIARY CARE CENTER

2021 ◽  
pp. 22-25
Author(s):  
Yogesh Thawal ◽  
Meenal M. Patvekar ◽  
Prashant Suryarao ◽  
Dipak Suresh Kolate ◽  
Shayari Jain ◽  
...  
Keyword(s):  
Birth Weight ◽  
Teenage Pregnancy ◽  
Post Partum ◽  
Care Center ◽  
Tertiary Care ◽  
First Trimester ◽  
Tertiary Care Center ◽  
College Hospital ◽  
Live Births ◽  
Normal Birth

Background: Teenage pregnancies are associated with high degree of maternal and neonatal complications. As many adolescents are neither physically nor psychologically ready for pregnancy or childbirth, this reproductive event makes them more vulnerable to complications resulting in devastating health sequences for them. Objectives: Our objective is to study feto-maternal outcomes in teenage pregnancy for betterment of society & for abetting economic burden on country. This observational Materials & Methods: study was done over 2 years at our tertiary care center - Dr DY Patil Medical College, Hospital and Research Institute, Pimpri, Pune. A total of 205 participants were included in the study after obtaining informed consent from the patients who satised the inclusion of age more than or equal to 18 years and lesser than 20 years. Operative interventions like D&E Results : , LSCS were increased in teenage pregnancies with emergency LSCS in 36.58% of the participants. First trimester & Antepartum complications were common in teenage pregnancies. Even Intrapartum & Post partum complications were contributed signicantly to feto-maternal morbidity & mortality . 54.04% had low birth weight and only 40.91% had normal birth weight. A total 64 NICU admissions were needed from 193 live births. Of these 12 expired in early neonatal period (<7 days) whereas 7 expired between 7 to 28 days. Among those who survived, almost 40 % had perinatal hypoxia. There were 96.98% live births whereas 3.01% IUD. Conclusion : Teenage pregnancy is a condition which gives rise to further complications and affects both the maternal as well as the neonatal health. Hence it is important that at every level of the society there is awareness regarding sexual education, use of contraceptives and the ill effects of teenage pregnancy.

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